Toxicology

<p>Applications Used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gulcan, H., et al.: Chem. Res. Toxicol., 21, 1503 (2008), Toropov, A., et al.: Bioorg. Med. Chem., 16, 5999 (2008), Franco, A., et al.: Envir. Toxicol. Chem., 28, 2018 (2009), Jensen, S., et al.: J. Agric. Food Chem., 57, 5872 (2009),<br></p>

<p>Applications Ethiprole is a phenylpyrazole based insecticide used in rice ecosystem on Trichogramma japonicum, and egg parasitoid of rice lepidopterans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, X.P., et al.: J. Economic. Entomol., 105, 92 (2012); Gomez-P. M.L., et al.: J. Chromatograph. A., 1248, 130 (2012);<br></p>

<p>Applications Tianeptine Sodium Salt is a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.<br>References Malen, C., et al.: Experientia, 28, 811 (1972),<br></p>

<p>Applications Labelled trichloroethylene metabolite<br>References Werner, M., et al.: Chem. Res. Toxicol., 9, 41 (1996), Bruning, T., et al.: Toxicol. Sci., 41, 157 (1998), Newman, D., et al.: Drug Metab. Disposition, 35, 43 (2007),<br></p>

<p>Applications Methyclothiazid, is derivative of Hydrochlorothiazide (H714560), which is a diuretic used in the hospital or for personal use to promote excess fluid associated with congestive heart failure. It is also used as an antihypertensive.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981),<br></p>

<p>Applications Broflanilide is a pesticide for controlling animals and microbial pests such as unwanted insects. Broflanilide is a prominent insecticide because of it’s effective against pests with resistance to cyclodienes and fipronil. Broflanilide is metabolized to desmethyl-broflanilide that acts as a noncompetitive resistant-to-dieldrin (RDL) γ-aminobutyric acid (GABA) receptor antagonist.<br>References An, X., et al.: J. Sep. Sci., 41, 4515 (2018); Zhao, P., et al.: Nongyao Kexue Yu Guanli, 36, 23 (2015); Jeanmart, S., et al.: Bioorg. Med. Chem., 24, 317 (2016); Nakao, T., et al.: Bioorg. Med. Chem., 24, 372 (2016)<br></p>

<p>Applications A new antitumor derivative of Vinblastine; a dimeric Vinca alkaloid for cancer therapy.<br>References Chakravarty, et al.: J. Med. Chem., 26(5), 638 (1983), Christensson., et al.: Eu.r J. Biochem., 194, 755 (1990), Mayer, et al.: J. Med. Chem., 34, 3029 (1991), Yu, H., et al.: Clin. Biochem., 27, 75 (1994)<br></p>

<p>Applications An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>

<p>Applications 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide-d3 is the isotope labelled analog of 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide (D453415); a compound that has been shown to be one of the potential novel biomarkers of peroxisome proliferation in the rat.<br>References Ringeissen, S., Biomarkers, 8, 240 (2003); Shibata, K., et al.: Biosci. Biotech. and Biochem., 77, 2105 (2013)<br></p>

<p>Applications Harpagoside is an iridoid glycoside along with with Harpagide (H105270), the potential to be strong anti-inflammatory agents providing the bulk of the observed effects from their plant origins.<br>References Zhang, L. et al.: Bioorg Med. Chem., 19, 4882 (2011); Wen, B. et al.: J. Ethnopharm., 147, 503 (2013);<br></p>

<p>Applications Androsterone glucuronide (ADT-G) is one of the major circulating C19-steroid metabolites in humans. Exaggerated Androsterone (A637535) metabolism is observed in hyper-androgenic as well as in some normo-androgenic women with acne and androsterone glucuronide could be a marker in differentiating acne and hirsutism in hyperandrogenic women.<br>References Thompson, D.L. et al.: Clin. Endocrinol., 32, 283 (1990); Stener-Victorin, E. et al.: J. Clin. Endocrinol. Metab., 95, 810 (2010);<br></p>

<p>Applications Dicamba is a herbicide. Dicamba functions by increasing plant growth rate. At sufficient concentrations, the plant outgrows its nutrient supplies and dies. Dicamba has been approved by the EPA for use on genetically modified soybeans and cotton.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br>References Oehler, D.D., et al.: J. Agric. Food Chem., 28, 685 (1980); Griffin, J., et al.: Weed Techno., 27, 696 (2013); Chem. and Eng. News, Nov. 14, 2016, p. 17<br></p>

<p>Applications Antitussive. Chain between 6 and 17 units of ethylene glycol with the major product containing 10 units.<br>References Scholtissek, C., et al.: Antiviral Res., 38, 213 (1998), McGovern, S., et al.: J. Med. Chem., 45, 1712 (2002), Regenthal, R., et al.: Hum. Exp. Toxicol., 21, 343 (2002),<br></p>

<p>Applications Etoricoxib-d6 is the labelled analog of Etoricoxib (E934100), a specific inhibitor of COX-2 .<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>

<p>Applications Spirotetramat-​keto-​hydroxy can be used in analytical study and biological study multi-​residue method for the determination of pesticides and pesticide metabolites in honeybees by liquid and gas chromatography coupled with tandem mass spectrometry-​Honeybee poisoning incidents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kiljanek, T., et al.: J Chromtagr A, 1435, 100 (2016)<br></p>

<p>Applications Alanycarb is a oxime carbamate inseciticide with acetylcholinesterase inhibitor activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dulin, F., et al.: Ecotoxicol. Environ. Safety., 90, 183 (2013); Kawazu,K., et al.: J. App. Entomol. 135, 647 (2011);<br></p>

<p>Applications Mofebutazone is an anti-inflammatory drug used on the gastrointestinal and renal tissues.<br>References Khayyal, M.T., et al.: Int. J. Clin. Pharmacol. Res., 15, 145 (1995); Safwat, S.M., et al.: Drug. Deve. Indust. Pharm., 15, 2605 (1988);<br></p>

<p>Applications A fluorimetric substrate for cytochrome P450 IAI. Inhibits vasorelaxant responses to acetylcholine.<br>References Donato, M.T., et al.: Anal. Biochem., 213, 29 (1993), Oyekan, A.O., et al.: J. Pharmacol. Exp. Ther., 268, 262 (1994)<br></p>

<p>Applications N-Octanoyl-d15-glycine is labelled N-Octanoylglycine (O239735) which is a derivative of Glycine (G615990) and is an amphiphilic lipoamino acid commonly used in cosmetics for its antibacterial properties. N-Octanoylglycine is the active ingredient in products designed to treat seborrheic dermatitis on the scalp and acne prone skin.<br>References Georgalas, A.: Cosmet. Toiletries, 127, 96 (2012); Nakamura, S.: Frag. J., 39, 36 (2011)<br></p>

<p>Stability Hygroscopic<br>Applications Zoledronic-d3 Acid is the labeled analogue of Zoledronic Acid (Z623500), a biphosphonate bone resorption inhibitor.<br>References Green, J.R., et al.: J. Bone Min. Res., 9, 745 (1994); Risser, F., et al.: J. Pharm. Biomed. Anal., 15, 1877 (1997); Body, J.J., Cancer, 80, 1699 (1997)<br></p>

<p>Applications Labelled xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978), Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005), Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005),<br></p>

<p>Applications Labelled racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.<br>References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);<br></p>

<p>Applications Chenodeoxycholic Acid 24-Acyl-β-D-glucuronide is a glucuronide metabolite of Chenodeoxycholic Acid (CDCA) (C291900).<br>References Alme, B., et al.: J. Steroid Biochem., 13, 907 (1980), Goto, J., et al.: Steroids, 63, 186 (1998), Barbier, O., et al.: J. Steroid Biochem. Mol. Biol., 85, 235 (2003),<br></p>

<p>Applications A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>

<p>Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>

<p>Applications A metabolite of Aniline. Arylamines are predominantly conjugated by constitutive enzyme forms in the liver.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Axelrod, J., et al.: J. Biol. Chem., 232 835 (1958), Lilienblum, W., et al.: Biochem. Pharmacol., 33, 2041 (1984),<br></p>

<p>Applications Bisoctyl Dimethyl Ammonium Chloride is used in the precipitation of silver ions and may be applied to the novel formation if nanoprecipitations using single reverse micellar system.<br>References Husein, M. et al.: Langmuir, 19, 8467 (2003);<br></p>

<p>Stability Hygroscopic<br>Applications Diquat-d8 Dibromide (dipyridine-d8) is a useful isotopically labeled compound of Diquat Dibromide Monohydrate (D492900(M)), which is a contact herbicide used also to produce desiccation and defoliation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brian, et al.: Nature, 181, 446 (1958), Gaines, T.B., et al.: Fundam. Appl. Toxicol., 7, 299 (1986),<br></p>

<p>Applications A compound used in products for promoting skin cleanliness and health.Water content not determined.<br>References Lin, J., et al.: Biotechnol. Bioeng., 83, 168 (2003), Gabriel, M., et al.: Bioconjug. Chem., 17, 548 (2006),<br></p>

<p>Stability Hygroscopic<br>Applications Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),<br></p>

<p>Applications Methoxyphenone is a pesticidal compound, and it is used in preparation of Nitrones as herbicides.<br>References Campbell, Matthew J., et al:. PCT Int. Appl., (2018); Garizi, N., et al:.U.S. Pat. Appl. Publ., (2014);<br></p>

<p>Applications (R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3 is labelled (R)-10-Monohydroxy-10,11-dihydro Carbamazepine which is the metabolite of Oxcarbazepine (OXC) and Eslicarbazepine acetate, (BIA 2-093, ESL), novel central nervous system drugs.<br>References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),<br></p>

<p>Applications Metconazole is a conazole based fungicide used for the control of black sigatoka disease on bananas. Metconazole acts primarily as an inhibitor of ergosterol biosynthesis which interferes with the synthesis of fungal cell membranes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cools, H.J., et al.: Pest. Manage. Sci., 68, 1034 (2012); Nam, M.H., et al.: Res. Plant. Disease., 17, 295 (2011);<br></p>

<p>Applications Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996),<br></p>

<p>Applications KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor. Studies show that KU-0058948 is a potent agonist that activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells. KU-0058948 induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro<br>References Klevernic, I.V. et al.: FEBS Lett., 583, 680 (2009); Gaymes, T.J. et al.: Haematologica, 94, 638 (2009);<br></p>

<p>Applications Cacodylic acid is used for dermatologic treatment in cronic eczema, anemia and as a tonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mandal, B., et al.: Talanta, 58, 201 (2002), Naranmandura, H., et al.: Chem. Res. Toxicol., 20, 616 (2007), Naranmandura, H., et al.: Toxicol. Appl. Pharmacol., 227, 390 (2008), Violin, J., et al.: J. Biol. Chem., 283, 2949 (2008),<br></p>

<p>Applications Apremilast is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.<br>References Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 (2013);<br></p>

<p>Applications Dinosam is used in preparation of Chitosan gel and application thereof in shampoo for preventing alopecia.Also, used in methods and formulations for preventing downward migration of agricultural materials.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Qiu, Y., et al.: Faming Zhuanli Shenqing, (2020); Shieh, A., et al.: PCT Int. Appl., (2020);<br></p>

<p>Applications tert-Butyl Pitavastatin is used to prepare hemicalcium salt.<br>References Van Der Schaaf, P., et al.: PCT Int. Appl. (2004), WO 2004072040 A1 20040826.<br></p>

<p>Applications Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable.<br>References Choudhary, S., et al.: Chem. Biol. Drug. Des., 80, 693 (2012); Ejim, L., et al.: Nature. Chem. Biol., 7, 348 (2011); Giorgetti, S., et al.: J. Biol. Chem., 286, 2121 (2011);<br></p>

<p>Applications (2S,3S)-Hydroxybupropion hydrochloride (CAS# 106083-71-0) is a useful research chemical compound.<br></p>

<p>Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>

<p>Applications Labelled Dacarbazine (D101400). Dacarbazine is used as an antineoplastic for treatment of malignant melanoma and sarcomas.<br>References Shealy, et al.: Biochem. Pharmacol., 11, 674 (1962), Carter, et al.: Eur. J. Cancer, 8, 85 (1972),<br></p>

<p>Applications Perampanel is a novel, noncompetitive AMPA receptor antagonist for the treatment of epilepsy. Also in the treatment of primary generalized tonic-clonic seizures in idiopathic generalized epilepsy. Perampanel is a selective non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor antagonist that reduces neuronal excitation (1,2,3,4).<br>References (1) Shih, J., et al.: Therap. Clinical Risk Management, 9, 285 (2013)(2) Rogawski, M. A., et al.: Epilepsy Curr., 11, 56 (2011)(3) Franco, V., et al.: Ther Drug Monit. 38, 744 (2016) (4) Rudzinski, L. A., et al.: J Investig Med. 64, 1087 (2016)<br></p>

<p>Applications Carbocisteine is a mucolytic agent used in the treatment of respiratory disorders ranging from the influenza virus infection to chronic obstructive pulmonary disease (COPD).<br>References Stevenson, G.B. et al.: Eur. Resp. J., 27, 865 (2006); Suer, E. et al.: J. Infect. Chemother., 14, 333 (2008); Yamaya, M. et al.: Am. J. Physiol., 299, L160 (2010);<br></p>

<p>Applications Oxymatrine-d3, is a labeled analogue of Oxymatrine (O876300), an anti-tumor agent triggering apoptosis in human leukemia cells.<br>References Liu, J. et al.: Tumor Biol., 35, 5409 (2014); Wang, C. et al.: Am. J. Chinese Med., 42, 543 (2014);<br></p>

<p>Applications Selective pre-emergence herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viste, K.L., et al.: Science, 167, 280 (1970), Yoshii, K., et al.: J. Agric. Food Chem., 48, 2502 (2000), Paya, P., et al.: Anal. Bioanal. Chem., 389, 1697 (2007),<br></p>

<p>Applications Labelled (S)-Amphetamine. CNS stimulant; anorexic. More active isomer of Amphetamine. Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.Controlled substance (stimulant).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 85, 119 (1945), Behrendt, W.A, et al.: Arzneim.-Forsch., 13, 711 (1963), Seiden, L.S., Annu. Rev. Pharmacol. Toxicol., 32, 639 (1993),<br></p>

<p>Applications Cephalosporin Antibiotic.<br>References Murata, H., et al.: J. Hepatol., 38, 573 (2003), Osawa, M., et al.: Legal Med., 10, 143 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009),<br></p>

<p>Applications A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),<br></p>

<p>Applications Eszopiclone is the active stereoizomer of Zopiclone and belongs to the class of drug known as cyclopyrrones. It is a nonbenzodiazepine hypnotic agent used as a treatment for insomnia.This is a controlled substance (depressant) in the US but not in Canada.<br>References Gottesmann, C., et al.: Eur. J. Neurosci., 10, 409 (1998), Yoshimoto, M., et al.: Eur. Neuropsychopharmacol., 9, 29 (1999),<br></p>

<p>Applications Labelled Tryptamine (T894600). Occurs in plants.<br></p>

<p>Applications Tripamide is a diuretic.<br>References Ogihara, T., et al.: Hypert. Res., 32, 163 (2009)<br></p>

<p>Stability Light Sensitive<br>Applications S-Hydroprene, is an insect growth regulator used as an insecticide. It is used against cockroaches, beetles, and moths.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Environmental Protection Agency, Federal Register, 62, 61645 (1997); Bell, H. A., et al.: J. Stored Produc. Res., 35, 117 (1999);<br></p>

<p>Applications A labelled opioid analgesic. Used as a substitute to morphine for postoperative pain in children.<br>References Lundeberg, S. et al.: Acta Anaesthesiol. Scand., 54, 435 (2010); Christensen, T. et al.: Neurosci. Res. Comm., 26, 77 (2000);<br></p>

<p>Applications Calcitonin, Salmon is a calcium regulating hormone which exhibits hypocalcaemic and hypophosphatemic properties.<br></p>

<p>Applications Lofentanil is a very potent and long-acting opiate agonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lembeck, F., Donnerer, J.: Eur. J. Pharmacol., 114, 241 (1985)<br></p>

<p>Applications CP 1282 is the tautomer of the antibiotic Cefotetan (C242970) with similar degradation rates.<br>References Koshiro, A. et al.: Chem. Pharm. Bull., 37, 1864 (1989); Naber, K. et al.: Zeitsch. Antmickrob. Antineoplast. Chemother., 2, 161 (1984);<br></p>

<p>Applications A metabolite of Mirtazapine (M365000). This compounds contains some of the alpha anomer.<br>References Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Dahl, M., et al.: Clin. Drug Invest., 13, 37 (1997),<br></p>

<p>Applications Dichlorodipropyltin is a diorganotin dihalide which has broad applications in both laboratory and industry. The Dichlorodipropyltin class of compounds can be used as a poly(vinyl chloride) stabilizers, fungicides and insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chandrasekaran, R.K. et al.: J. Organometallic Chem. 3, 215 (1981);<br></p>

<p>Applications Diuretic and antihypertensive.<br>References Twagirumukiza, M., et al.: Trop. Med. Int. Health, 15, 350 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Peters, R., et al.: Anal. Bioanal. Chem., 396, 2583 (2010),<br></p>

<p>Applications Pentachlorophenol Sodium Salt can be used in biological study of evaluation of interaction between pesticides and a cell membrane model by surface plasmon resonance spectroscopy analysis. One of the new POPs under the Stockholm Convention.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moriwaki, H., et al.: J Agr Food Chem, 65, 5390 (2017)<br></p>

<p>Applications The labeled version of Meclizine (M202700(P)), which is an antiemetic.<br>References Cohen, B., et al.: Arch. Neurol., 27, 129 (1972),<br></p>

<p>Applications Labelled Doxazosin (D537500). Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.<br>References Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),<br></p>

<p>Applications Bentazon-d7 is deuterium labelled Bentazon (B120580), which is a herbicide.<br>References Ghirardello, D., et al.: Environ. Sci. Technol., 44, 9010 (2010), Frihauf, J., et al.: Weed Technol., 24, 262 (2010), Rotroff, D., et al.: Toxicol. Sci., 117, 348 (2010),<br></p>

<p>Applications Zolmitriptan is a serotonin 5HTID-receptor agonist and used to treat migraine (1,2,3).<br>References (1) Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995)(2) Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996)(3) Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>

<p>Applications 4-(Trifluoromethyl)nicotinoyl Glycine-13C2,15N is the isotope labelled analog of 4-(Trifluoromethyl)nicotinoyl Glycine (T791375); a metabolite of Flonicamid (F405710), which is a novel insecticide with rapid inhibitory effect against aphid feeding.<br>References Lee, Sung Woo., et al.: J. Chrom. A., 1218(28), 4366-4377 (2011); Hengel, Matt J., et al.: J. Agr. Food Chem., 55(20), 8033-8039 (2007); Morita, M., et al.: Pest. Manag. Sci.,63, 969 (2007); Sabatino, L., et al.: Food. Additive. Contamin., 6, 11 (2013);<br></p>

<p>Applications Verapamil-d3 Hydrochloride is the labeled analogue of Verapamil Hydrochloride (V125000), which is a calcium channel blocker, antihypertensive, antianginal, and antiarrhythmic (class IV).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981); Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>

<p>Applications Novaluron is an insect growth regulator and shows killing effect against various larvae of genus Lepidoptera, Coleoptera, Hemiptera and Diptera. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lefebvre, M., et al.: J. Econmic. Entomol., 105, 866 (2012); Brock, T.C.M., et al.: Environ. Sci. Pollu. Res., 19 3610 (2012);<br></p>

<p>Applications Antilipemic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metz, G., et al.: Arzneim.-Forsch., 27, 1173 (1977), Hassan, A.M., et al.: Anal. Profiles Drug Subs., 11, 197 (1982),<br></p>

<p>Applications Phentermine is an appeitie suppressant used in the treatment of obesity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ryan D.H., et. al.: Obesity Research, 7, 313 (1999); Wadden, T.A., et. al.: Oesity Research, 5, 218 (1997)<br></p>

<p>Applications 2,4,5-Trichlorophenol is used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Amer, S. et al.: Cytologia, 39, 633 (1974); Xu, X. wt l.: Occup. Environ. Med., 68, 557 (2011); Sinclair, C.J. et al.: Environ. Sci. Technol., 37, 4617 (2003);<br></p>

<p>Applications Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>

<p>Applications 2-Hydroxy-5-(trifluoromethyl)pyridine (cas# 33252-63-0) is a compound useful in organic synthesis.<br></p>