
Toxicology
Found 13565 products of "Toxicology"
Naloxone-d5 3-β-D-Glucuronide
CAS:Controlled ProductApplications Naloxone-d5 3-β-D-Glucuronide is a labelled metabolite of Naloxone ((N285000). Narcotic antagonist.
References Scheurer, U., et al.: J. Pharmacol. Exp. Ther., 252, 1324 (1990), Yuan, C., et al.: Clin. Pharmacol. Ther., 59, 469 (1996), Ulens, C., et al.: Biochem. Pharmacol., 62, 1273 (2001), Comert, M., et al.: Eur. J. Pharmacol., 511, 183 (2005),Formula:C25H24D5NO10Color and Shape:NeatMolecular weight:508.53Benzyldecyldimethylammonium Chloride
CAS:Controlled ProductApplications Benzyldecyldimethylammonium Chloride is a biocide.
References Lee, M., et al.: Appl. Micro. Biotech., 87, 1109 (2010); Campanac, C., et al.: Antimicrob. Agents Ch., 46, 1469 (2002); Shen, J., et al.: Anal. Chem., 62, 116 (1990)Formula:C19H34N·ClColor and Shape:Off-WhiteMolecular weight:311.93(S)-Haloxyfop-methyl
CAS:Controlled ProductFormula:C17H19NO4Color and Shape:NeatMolecular weight:301.337O-Desethyl Dapagliflozin (>80%)
CAS:Applications O-Desethyl Dapagliflozin is derivative of antidiabetic drug Dapagliflozin (D185370), which is sodium-glucose transporter 2 inhibitor.
References Kasichayanula, S., et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Xu, G., et al.: J. Med. Chem., 57, 1236 (2014);Formula:C19H21ClO6Purity:>80%Color and Shape:Off-White To Light YellowMolecular weight:380.82trans-Permethrin
CAS:Controlled ProductApplications trans-Permethrin is the trans isomer of Permethrin (P288500) which is a common synthetic pyrethoid insecticide with low mammalian toxicity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Itaya, N., et al.: ACS Sym. Ser., 42, 45 (1977); Elliott, M., et al.: Nature, 246, 169 (1973);Formula:C21H20Cl2O3Color and Shape:Light BrownMolecular weight:391.29Sitagliptin Phosphate
CAS:Controlled ProductApplications Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
References Kim, D., et al.: J. Med. Chem. 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)Formula:C16H15F6N5O·H3O4PColor and Shape:NeatMolecular weight:505.31Cloxacillin-13C4 Sodium Salt
CAS:Controlled ProductStability Hygroscopic
Applications Labelled analogue of Cloxacillin, an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
References Gibbs, D.L. et al.: Curr. Microbiol., 2, 239 (1979); Dmitrova, D. et al.: Farmat., 48, 28 (2001); Craven, N. et al.: Res. Vet. Sci., 29, 57 (1980);Formula:C15C4H17ClN3NaO5SColor and Shape:Off-WhiteMolecular weight:461.83Mandestrobin
CAS:Controlled ProductApplications Mandestrobin is a novel fungicide having a methoxyacetamid structure. Mandestrobin also shows safer profiles for human health and the environment.
References Hirotomi, D., & Kiguchi, S.: PCT Int. Appl., WO 2017026526 A1 20170216 (2017)Formula:C19H23NO3Color and Shape:WhiteMolecular weight:313.394-Bromo-2-chlorophenol
CAS:Applications 4-Bromo-2-chlorophenol
Formula:C6H4BrClOColor and Shape:NeatMolecular weight:207.45Ropinirole-d7 Hydrochloride
CAS:Controlled ProductApplications Ropinirole-d7 Hydrochloride is the labeled analogue of Ropinirole Hydrochloride (R641000), an antiparkinsonian agent. A selective dopamine D2-receptor agonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eden, R.J., et al.: Pharmacol. Biochem. Behav., 38, 147 (1991); Rascol, O., et al.: Mov. Disord., 13, 39 (1998),Formula:C162H7H17N2O·ClHColor and Shape:NeatMolecular weight:303.88N-Desacetyl 5-Azido Oseltamivir
CAS:Controlled ProductApplications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.
References Williams, M., et al.: Bioorg. Med. Chem. Lett., 7, 1837 (1997),Formula:C14H24N4O3Color and Shape:NeatMolecular weight:296.372'-Deoxyadenosine Monohydrate-13C5
CAS:Controlled ProductApplications Used in the synthesis of labelled 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.
References Gordon, C., et al.: J. Med. Chem., 48, 1 (2005), Ikejiri, M., et al.: Bioorg. Med. Chem., 15, 6882 (2007),Formula:C513C5H13N5O3•H2OColor and Shape:Off-WhiteMolecular weight:274.22Triflusulfuron-methyl
CAS:Controlled ProductApplications Triflusulfuron-methyl, is a widely used sulfonylurea herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Song, N., et al.: Huanjing Kexue, 33, 4400 (2012);Formula:C17H19F3N6O6SColor and Shape:WhiteMolecular weight:492.43Pyridaben
CAS:Controlled ProductApplications Pyridaben is a pyridazinone derivative used as an insecticide and acaricide. In the European Union, Pyridaben has been authorized for use as an insecticide and acaricide from 1 May 2011. In Germany, Austria and Switzerland, no plant protection products containing this active substance are authorized. Pyridaben is a colorless solid that is practically insoluble in water. Useful in cannabis testing kits as a component of pesticide mixes (P698235).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wadleigh, R., et al.: J. Chem. Ecol.,14, 1279 (1988), Hirata, K., et al.: J. Pestic. Sci., 20, 177 (1995), Chen, F., et al.: J. Entomol. Sci., 42, 296 (2007),Formula:C19H25ClN2OSColor and Shape:BeigeMolecular weight:364.93Ceftizoxime Sodium Salt (Mixture of Diastereomers)
CAS:Controlled ProductFormula:C13H12N5O5S2·NaColor and Shape:NeatMolecular weight:405.38Rutin
CAS:Stability Hygroscopic
Applications Found in many plants, especially the buckwheat plant. Identity with Ilixanthin. Capillary protectant. Rutin is colored brown by tobacco enzyme under experimental conditions.
References Harrison, et al.: J. Am. Pharm. Assoc., 39, 557 (1950), Humphreys, et al.: Econ. Bot., 18, 195 (1964), Khalifa, T.I., et al.: Anal. Profiles Drug Subs., 12, 623 (1983).Formula:C27H30O16Color and Shape:BeigeMolecular weight:610.52Tembotrione
CAS:Applications Tembotrione is one of the pesticides found in surface waters. It can also be found as pesticide residues in fruits and vegetables.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Moschet, C., et al.: Environ. Sci. Technol., 48, 5423 (2014); Wang, J., et al.: J. Agric. Food Chem., 62, 10375 (2014);Formula:C17H16ClF3O6SColor and Shape:Light Yellow To Light BeigeMolecular weight:440.82(rac-trans)-Bifenthrin-d5
CAS:Controlled ProductApplications The labelled trans-isomer of the third generation synthetic pyrethroid insecticide, Bifenthrin (B383000).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Plummer, E.L., et al.: Pestic. Sci., 14, 560 (1983), Trumble, J.T., et al.: J. Econ. Entomol., 81, 608 (1988), Ross, M., et al.: Biochem. Pharmacol., 71, 657 (2006), Hillegass, J., et al.: Toxicol. Sci., 102, 413 (2008),Formula:C23D5H17ClF3O2Color and Shape:Off-WhiteMolecular weight:427.899Carboxine
CAS:Controlled ProductApplications Carboxine is an fungicide used for the control of fruit rot of custard apple.
References Kosiada, T., et al.: J. Plant. Protect. Res,, 51, 342 (2011); Goswami, S., et al.: J, App. Natural. Sci., 4, 264 (2012);Formula:C12H13NO2SColor and Shape:Off-WhiteMolecular weight:235.3tau-Fluvalinate (Mixture of Diastereomers)
CAS:Applications τ-Fluvalinate is a synthetic pyrethroid aracacide. τ-Fluvalinate is commonly used to control Varroa jacobsoni (a parasitic mite) in honey bee colonies.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Delaplane, K.S. et al.: J. Econ. Entomol., 88, 1206 (1995); Ferrer-Dufol, M. et al.: J. Apicul. Res., 34, 147 (1995); Lindberg, C.M. et al.: J. Econ. Entomol., 93, 189 (2000);Formula:C26H22ClF3N2O3Color and Shape:Light YellowMolecular weight:502.91Mefenpyr-diethyl
CAS:Applications Mefenpyr-diethyl is used in herbicidal and herbicide-safener combinations as a resistant breaking solution for modern agriculture.
References Lindell, S., et al.: ACS Symposium Series, 1204, 219 (2015); Taylor, V. L., et al.: Environ. Exper. Bot., 88, 93 (2013)Formula:C16H18Cl2N2O4Color and Shape:BeigeMolecular weight:373.23Acipimox-d4
CAS:Controlled ProductApplications Labelled antilipemic.
References Fuccella, L.M., et al.: Clin. Pharmacol. Ther., 28, 790 (1980), Lovisolo, P.P., et al.: Pharmacol. Res. Commun., 13, 151 (1981), Aktories, K., et al.: Arzneim.-Forsch., 33, 1525 (1983), Boatman, P., et al.: J. Med. Chem., 51, 7653 (2008), Rigazio, S., et al.: Am. J. Physiol., 295, E413 (2008),Formula:C6H2D4N2O3Color and Shape:Off-White To BeigeMolecular weight:158.15Isoxaflutole
CAS:Controlled ProductApplications Isoxaflutole is an pesticide used to selectively control both grass and broad-leaved weeds in maize and sugar cane. Isoxaflutole is known to work by inhibiting the enzyme 4-Hydroxyphenylpyruvate dioxygenase (HPPD) which results in the disruption of pigment biosynthesis.
References Fillosls, E.F., et al.: Int. Sugar. J., 115, 135 (2013); Laini, A., et al.: Sci. Total. Environ., 438, 312 (2012);Formula:C15H12F3NO4SColor and Shape:NeatMolecular weight:359.32Glufosinate Ammonium
CAS:Stability Hygroscopic
Applications Used as a herbicide.
References Abbas, H., et al.: J. Agric. Food Chem., 50, 5246Formula:C5H11NO4P·H4NColor and Shape:White To BeigeMolecular weight:198.16Fenclorim
CAS:Controlled ProductApplications Herbicide safener.
References Lee, H., et al.: Eur. J. Med. Chem., 40, 862 (2005), Wright, S., et al.: Bioorg. Med. Chem. Lett., 17, 5638 (2007), Brazier-Hicks, M., et al.: J. Biol. Chem., 283, 21102 (2008), Vinggaard, A., et al.: Chem. Res. Toxicol., 21, 813 (2008),Formula:C10H6Cl2N2Color and Shape:BeigeMolecular weight:225.07Quinmerac
CAS:Applications Auxin-type herbicide.
References Ecker, J., et al.: Science, 268, 667 (1995), Grossmann, K., et al.: Pestic. Sci., 52, 111 (1998), Martin, P., et al.: Environ. Toxicol. Chem. 19, 2987 (2000), Grossmann, K., et al.: J. Exp. Bot., 52, 1811 (2001), van Eerd, L., et al.: Weed Res., 44, 355 (2004),Formula:C11H8ClNO2Color and Shape:ColourlessMolecular weight:221.64Ibogaine Hydrochloride
CAS:Controlled ProductApplications Ibogaine Hydrochloride is a naturally occurring psychoactive substance. It is a β-carboline derivative that cause both hallucinations and tremor.
References O’Hearn, E., et al.: Neurosci., 55, 303 (1993)Formula:C20H26N2O·ClHColor and Shape:WhiteMolecular weight:346.89Tecloftalam Imide
CAS:Controlled ProductApplications Tecloftalam Imide is a derivative of Tecloftalam (T013700), an agrochemical fungicide. Tecloftalam is used for the control of rice bacterial leaf blight.
References Nakagami, K. et al.: Nip. Noyak. Gak., 5, 511 (1980); Kirkpatrick, D. et al.: J. Agric. Food Chem., 29, 608 (1981); Takahi, Y. et al.: Jap. Past. Info., 46, 25 (1985);Formula:C14H3Cl6NO2Color and Shape:NeatMolecular weight:429.9Chlorpyrifos
CAS:Controlled ProductApplications Insecticide; acaricide.This compound is a contaminant of emerging concern (CECs).Useful in cannabis testing kits as a component of pesticide mixes (P698230).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smith, G.N., et al.: J. Agric. Food Chem., 15, 132 (1967), Schafer, et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972)Formula:C9H11Cl3NO3PSColor and Shape:ColourlessMolecular weight:350.59Fluasterone
CAS:Controlled ProductApplications A synthetic derivative of Dehydroepiandrosterone. The reduced androgenicity of Fluasterone may obviate toxicities associated with the androgenicity of the parent compound. Antitumor agent. Used in clinical trials for prostate cancer prevention.
References Bentley, P., et al.: Food Chem. Toxicol., 31, 857 (1993), Rao, K., et al.: Cancer Res., 59, 3084 (1999), Masuzaki, H., et al.: Science, 294, 2166 (2001), Osawa, E., et al.: Life Sci., 70, 2623 (2002),Formula:C19H27FOColor and Shape:White To Off-WhiteMolecular weight:290.42Tiazofurin
CAS:Controlled ProductStability Very Very Hygroscopic
Applications Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5'-monophosphate (IMP) dehydrogenase.
References Streeter, D.G. et al.: Biochem. Biophys. Res. Comm., 115, 544 (1983); Boritzki, T. et al.: Biochem. Pharmacol., 34, 1109 (1985); Malek, K. et al.: Leuk. Res., 28, 1125 (2004);Formula:C9H12N2O5SColor and Shape:NeatMolecular weight:260.27Sumatriptan-d6 Succinate
CAS:Controlled ProductFormula:C142H6H15N3O2S·C4H6O4Color and Shape:NeatMolecular weight:419.53Artesunate-d4
CAS:Controlled ProductApplications Labelled derivative of Artemisinin. Antimalarial.
References Zhao, Y., et al.: J. Nat. Prod., 49, 139 (1986), Lin, A.J., et al.: J. Med. Chem., 30, 2147 (1987), Price, R. N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000),Formula:C19H24D4O8Color and Shape:NeatMolecular weight:388.45N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-d7 (Mixture of Diastereomers)
CAS:Controlled ProductStability Hygroscopic
Applications Metabolites of butadiene.
References Heavner, D., et al.: J. Pharm. Biomed. Anal., 40, 928 (2006), Carmella, S., et al.: Chem. Res. Toxicol., 22, 734 (2009),Formula:C92H7H10NO5SColor and Shape:Light YellowMolecular weight:258.34Telmisartan-d7
CAS:Controlled ProductApplications Labelled Telmisartan (T017000). Telmisartan is an angiotensin II receptor antagonist.
References Wienen, W. et al.: Br. J. Pharmacol., 110, 245 (1993); Neutel, J.M. et al: Adv. Therap., 15, 206 (1998);Formula:C33H23D7N4O2Color and Shape:NeatMolecular weight:521.6634-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol O-b-D-Glucuronide Sodium Salt(Mixture of Diastereomers) (>90%)
CAS:Controlled ProductFormula:C16H22N3O9·NaPurity:>90%Color and Shape:White To Dark OrangeMolecular weight:423.35Isoprinosine
CAS:Applications Isoprinosine is a new combination of active substances for the treatment of chronic systemic diseases such as cancer. Isoprinosine is an immunomodulator; antiviral. The ratio is between 1: 2 : 2 to 1 : 3 : 3
References Mastino, A., et al.: Int. J. Cancer, 50, 493 (1992), Kim, Y., et al.: Mol. Cancer Therap., 8, 469 (2009),Formula:C10H12N4O5·3C9H9NO3·3C5H13NOColor and Shape:White To Off-WhiteMolecular weight:1115.23Lurasidone
CAS:Controlled ProductApplications Lurasidone (cas# 367514-87-2) is a useful research chemical.
Formula:C28H36N4O2SColor and Shape:NeatMolecular weight:492.68(±)-Sibutramine
CAS:Controlled ProductApplications (±)-Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.
References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998)Formula:C17H26ClNColor and Shape:Off White SolidMolecular weight:279.854-Hydroxy Atorvastatin-d5 Hemicalcium Salt
CAS:Controlled ProductApplications di(4-Hydroxy Atorvastatin-d5) Calcium Salt is a labeled metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)Formula:C66H58D10CaF2N4O12Color and Shape:Beige SolidMolecular weight:1197.4Meropenem-d6 (>90%)
CAS:Controlled ProductStability Unstable in Solution
Applications Meropenem-d6 is the labeled analogue of Meropenem, a carbapenem antibiotic. Antibacterial.
References Adams, M.D., et al.: J. Bacteriol., 190, 8053 (2008); Pattanaik, P., et al.: J. Biol. Chem., 284, 945 (2009); Mendes, R., et al.: J. Antimicrob. Chemother., 63, 55 (2009)Formula:C17H19D6N3O5SPurity:>90%Color and Shape:White To Light YellowMolecular weight:389.5Oxamyl
CAS:Applications Oxamyl is a pesticide used in the treatment and protection of crops from parasites and insects. Oxamyl is also useful in cannabis testing kits as a component of pesticide mixes (P698240).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C7H13N3O3SColor and Shape:Off-WhiteMolecular weight:219.26trans-3'-Hydroxy Cotinine-d3 N-β-D-Glucuronide
CAS:Controlled ProductApplications A Nicotine metabolite. Carcinogen.
Formula:C16H17D3N2O8Color and Shape:NeatMolecular weight:371.36Quintrione
CAS:Controlled ProductApplications Quintrione is herbicidal compound comprising Heterocyclic Amide compound and use thereof.
References Wang, Z., et al.:PCT Int. Appl., (2020);Formula:C16H11Cl2NO3Color and Shape:Off-WhiteMolecular weight:336.17Nithiazine
CAS:Controlled ProductApplications Nithiazine is a useful building block and insecticide.
References Quaranta, L.; et al.: WO 2018149851 (2018).Formula:C5H8N2O2SColor and Shape:NeatMolecular weight:160.194

