Biochemicals and Reagents

Asapiprant is a metabolic product of the drug asacol. It has been shown to have anti-inflammatory effects and has been used in studies to determine its efficacy in treating humans infected with covid-19 pandemic. Asapiprant has also been shown to be an effective diagnostic agent for detecting the presence of eicosanoids in nasal fluid. This compound has not yet been tested on animals or humans.

2-((5-Chloropyridin-2-yl)amino)-N-(3,5-difluorophenethyl)acetamide is a small molecule that inhibits the ion channels TRPM8 and TRPA1. It is an inhibitor of TRPM8 and has been shown to inhibit the activity of TRPA1 in vitro. It may be used as a research tool for studying protein interactions, receptor pharmacology, peptides, activator ligands, ion channels and ligand binding.

4-(3-(Methylsulfonyl)phenyl)-1-propylpiperidine is an analog that has shown promising results as an anticancer agent. It works by inhibiting protein kinases, which are enzymes involved in the growth and spread of tumors. This compound has been found to be effective against a variety of cancer cells, including those from human urine and Chinese medicinal plants. It induces apoptosis, or programmed cell death, in cancer cells by blocking the activity of specific kinases. This inhibitor shows great potential for the development of new cancer treatments.

SGI 1027 is an enteric-coated, citric acid-resistant, sensor-activated tablet that contains a liquid crystal material that changes color in response to pressure. The tablet is energized by pressing on the sensor and utilizes a frequency of 120Hz. It is designed for recording and pressurization of the stomach and intestines in order to diagnose motility disorders. SGI 1027 has been shown to be effective against symbol-resistant bacteria, such as Clostridium difficile.

Parathyroid hormone (PTH) is a peptide hormone that regulates the calcium and phosphate concentrations in the blood. It is produced by the parathyroid gland, located near the thyroid gland in the neck. PTH has three forms: amino-terminal proparathyroid hormone (PTH 1-34), amino-terminal parathyroid hormone fragment 34-84 (PTH 1-34 amide), and carboxy-terminal parathyroid hormone fragment 84-120 (PTH 1-84). The receptor for PTH is called the parathyroid hormone receptor (PTR). The binding of PTH to its receptor leads to activation of adenylate cyclase, which increases levels of intracellular cAMP.

Please enquire for more information about Ethyl p-(6-bromohexyloxy)benzoate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Desacetylcolchicine is a research tool used in the study of ion channels. It has been shown to be an activator of acetylcholine receptors, a ligand for nicotinic acetylcholine receptors, and a receptor for desacetylcolchicine. This compound has been shown to interact with cell biology by activating protein kinase C, phospholipase A2, and tyrosine kinase. Desacetylcolchicine also inhibits the activity of voltage-gated potassium channels, leading to an increase in excitability. Desacetylcolchicine is a high purity compound that is available as a white powder or crystalline solid.

AR 420626 is an advanced molecular sieve catalyst, which is derived from a robust zeolitic framework with precise pore architecture. Its mode of action is centered on facilitating selective adsorption and catalysis by exploiting the molecular dimensions within its crystalline structure. This enables the catalyst to achieve enhanced specificity and efficiency in molecular transformations.

AMT Hydrochloride is a synthetic tryptamine compound, which is derived from chemical synthesis methods. It is an analogue of alpha-methyltryptamine (AMT), specifically the hydrochloride salt form, enhancing its stability and solubility for laboratory settings. The mode of action involves acting as a non-selective agonist at serotonin receptors, primarily targeting the 5-HT2C and 5-HT2A receptors. This interaction results in psychoactive effects through the modulation of neurotransmitter systems, impacting serotonin pathways.

6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide is a research tool that can be used to study the function of ion channels. This compound has been shown to activate ligand receptors and bind to cell biology and antibody. 6-(3-(Cyclobutyl(2,3,4,5-tetrahydrobenzo[b]azepin-7(8H)yl)oxy)-Nmethylpyridinecarboxamide is an inhibitor of the protein interactions in cells. It can also be used as a pharmacology reagent for peptides and proteins. The CAS number for this compound is 945493-87-8.

PSB 0739 is a potent and selective adenosine receptor antagonist. It binds to the p2 receptor, which is a G-protein coupled receptor involved in cell signaling. PSB 0739 has been shown to inhibit contractility of bladder cells and granule cells, as well as inhibiting the release of noradrenaline from adrenergic nerve terminals. This compound also inhibits the activation of cardiac myocytes by increasing cytosolic calcium concentrations. PSB 0739 also blocks the clopidogrel-induced platelet aggregation in vitro and reduces platelet thrombus formation in vivo. PSB 0739 has been shown to block the binding of adenosine to A1 and A2A receptors, but does not bind to other adenosine receptors such as A3 or A4 receptors.

CC-115 is a small molecule that inhibits transcriptional regulation. It binds ATP-binding cassette transporters and blocks the export of fatty acids from the cell, which leads to increased levels of intracellular fatty acids and autophagy. CC-115 has shown efficacy in prostate cancer treatment, as well as squamous carcinoma. This drug has a potent inhibitory effect on gene expression and is currently undergoing clinical trials for use in high-risk disease.

2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid compound with a wide range of characteristics and applications. It has been found to have various effects on the body, including interactions with capsicum, electrolytes, and dopamine receptors. Additionally, it has shown potential in research related to Gaucher disease, chemokine signaling, glucosylceramide metabolism, and cancer studies.

Atosiban is a drug that is used to prevent preterm labor in pregnant women. It works by inhibiting the release of oxytocin from the hypothalamus, which decreases contractions and relaxes the uterus. Atosiban has been shown to be effective in decreasing the incidence of preterm birth in women with bacterial vaginosis who are at high risk for preterm delivery (e.g., those with a history of preterm labor). Clinical trials have shown that it may also be useful as an adjunct therapy in treating women with unexplained infertility and recurrent pregnancy loss. The drug binds to receptors on cells, which inhibits the release of intracellular calcium, thus preventing contraction of uterine muscle cells. This effect can be reversed by administration of estradiol benzoate or other drugs that affect receptor activity. It is not known whether atosiban affects fetal development during pregnancy or if it causes any effects on the mother's heart rate or body mass index after childbirth.

This Thyroglobulin VIF Light Tryptic Peptide Standard is useful in protein identification and quantitation studies such as liquid chromatography-tandem mass spectrometry (LC-MS/MS). The use of tryptic peptides overcomes the challenges of quantifying serum thyroglobulin levels using immunoassays through removing the risk of interferences from Thyroglobulin antibodies. Thyroglobulin is a thyroid hormone production substrate and thus an important biomarker for differentiated thyroid cancer.

Antithrombin III heavy tryptic peptide standard for protein identification and quantitation studies. Antithrombin III is a glycoprotein found in blood plasma and is involved in the regulation of the coagulation process.

IL-1 beta is a cytokine, which belongs to the IL-1 family of cytokines. It is a proinflammatory cytokine that induces fever and pain, and stimulates the immune system. IL-1 beta binds to the IL-1 receptor, which is a member of the class 1 cytokine receptor family. The binding activates phospholipase A2 and protein kinase C, which leads to an increase in prostaglandin production by cyclooxygenase 2. IL-1 beta also has been shown to inhibit ion channel activity and calcium uptake in cells.

Portion of EBV

CAY10685 is a peptide that has been shown to activate the protein receptor for angiotensin II. This receptor is found in many tissues, including brain, kidney, and heart. CAY10685 has also been shown to have an inhibitory effect on ion channels and ligand-gated ion channels. It may be used as a research tool or a pharmaceutical agent.

(6R)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydrobenzo[A]quinolizine-3-carboxylic acid binds to the GABAA receptor. It inhibits the binding of GABA and benzodiazepines and thus prevents the opening of chloride channels. This results in an increase in the neuronal activity of these neurons. (6R)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo - 6,7 - dihydrobenzo[A]quinolizine - 3 - carboxylic acid can be used as a research tool for studying protein interactions and activators as well as a ligand for receptors.

The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a Proteomics Tools product that has been designed to support the identification of biologically active peptides in proteomics. The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a tryptic peptide derived from human serum albumin and can be used as a precursor for the identification of other tryptic peptides in proteomic samples. The New England Peptide Company offers this product at a competitive price and with high quality.

CM 1 is a synthetic derivative of the natural compound apigenin. It inhibits the activity of matrix metalloproteinase-9 (MMP-9) and has been shown to suppress allergic symptoms in animal models. CM 1 has also been shown to be effective against some types of skin cancer, such as squamous carcinoma, when applied topically. CM 1 induces autophagy in vivo and has been shown to have biological properties that are similar to those of apigenin. This compound also promotes autophagy in cultured human cells by inhibiting mitochondrial membrane potential and increasing levels of reactive oxygen species (ROS).

MK-7246-d3 is a pancreas-selective β-cell receptor agonist that has been shown to have efficacy in the treatment of type 1 diabetes. The compound is able to inhibit the release of histamine from eosinophilic cells, which may be due to its ability to bind to histamine H1 receptors and inhibit calcium influx. MK-7246-d3 has also been shown to decrease acid secretion and increase bicarbonate secretion. These effects on the pancreas may be due to its ability to act as a potent antagonist at the gastric histamine H2 receptor. MK-7246-d3 has not yet been tested in humans but has shown promising results in vitro and in vivo animal models. This drug is also being evaluated for use in other diseases, such as chronic obstructive pulmonary disease, asthma, and rhinosinusitis.

L-asparaginase is a drug that inhibits the production of asparagine, which is an amino acid that is used in the synthesis of proteins. It has been shown to be effective against T-cell lymphomas, as well as other cancers such as leukemia and colorectal cancer. L-Asparaginase has been shown to inhibit mitochondrial functions in blood samples from patients with prostate cancer. This inhibition may lead to cell death. L-Asparaginase binds to the sephadex G-100 column in a similar manner to sodium citrate and prevents the formation of polymers when it combines with ATP. The enzyme can also be found in primary cells and liver cells, where it causes hypoglycemia by inhibiting glucose production. L-Asparaginase also inhibits dna synthesis by binding to DNA polymerases, preventing their attachment to nucleotide triphosphates (e.g., ATP).

Binds to microtubules

Obestatin is a neuropeptide that was first isolated from the mouse and rat hypothalamus. The Obestatin (Mouse, Rat)-EIA Kit is an in-house ELISA assay for the detection of mouse and rat obestatin. This kit can be used to detect obestatin in serum, plasma, or cell culture supernatant samples. It is a useful tool for studying the role of this peptide in various biological processes.

QL9 is a peptide that binds to light and has been shown to activate cells in the immune system. QL9 is a specific agonist for both CD4+ and CD8+ T cells and can be used as an adjuvant in a cell vaccine. The binding of this peptide to light activates T cells, which then produce cytokines such as IFN-γ, IL-2, and IL-12. It has been shown that QL9 can activate CD4+ T cells in the absence of antigen stimulation or antibody co-stimulation. This peptide also selectively binds to lipids, which are necessary for its function.

CCT 241533 is a Chinese herb that has been shown to have anti-cancer properties. It has been demonstrated to inhibit the growth of HL-60 cells and induce apoptosis in these cells. CCT 241533 also inhibits the proliferation of epidermal growth factor (EGF) and induces cell death in response to radiation. This drug also binds to toll-like receptors, which are proteins on the surface of cells that detect pathogens and initiate an immune response. CCT 241533 has been shown to inhibit polymerase chain reactions by competitive inhibition or by binding to DNA, preventing transcription or replication. CCT 241533 may be useful for the treatment of infectious diseases, such as tuberculosis, because it can bind to bacterial 16S ribosomal RNA and inhibit protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.
CCT 241533 has been shown in animal studies to be effective against cervical cancer due to its ability to bind