Heterocycles with Nitrogen (N)

Please enquire for more information about 3-(N-(2-(3,4-dimethoxyphenyl)ethyl)carbamoyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about 5-Methyl-3-(4-phenylpiperazinyl)cyclohex-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications 4-Ethylpyridine is a general chemical reagent used in the synthesis of substituted pyridines as well as diverse azacyclic compounds.<br>References Gandhamsetty, N. et al.: J. Am. Chem. Soc., 137, 15176 (2015); Chen, X. et al.: J. Coord. Chem., 68, 2835 (2015);<br></p>

<p>Applications N-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]Amine (cas# 147225-68-1) is a useful research chemical.<br></p>

<p>Applications 2-Aminopyrimidine-5-boronic Acid Pinacol Ester is used in the preparation of phosphoinositide-3-kinases (PI3K) inhibitors.<br>References Burger, M.T. et al.: ACS Med. Chem. Lett., 2, 774 (2011); Heffron, T.P. et al.: J. Med. Chdem., 55, 8007 (2012);<br></p>

<p>Applications Methyl 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboximidate is a useful reactant to study metabolites of orally active NO-independent pyrazolopyridine stimulators of soluble guanylate cyclase.<br>References Straub, A., et al.: Bioorg. Med. Chem., 10, 1711 (2002);<br></p>

<p>Applications Reagent used in Guanidino transfers.<br></p>

<p>Applications 2,2,6,6-Tetramethylpiperidine-1,4-diol is related to 4-Hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (H956500), which is a free radical scavenger. 2,2,6,6-Tetramethylpiperidine-1,4-diol has also been shown to be an in vitro and in vivo radioprotector. It is used as a reagent in stereoselective preparation of tetrasubstituted triarylated olefins via Pd-catalyzed sequential oxidative Heck arylation of alkenes with arylboronic acids using nitroxides as oxidants.<br>References Flather, M., et al.: Lancet, 355, 1575 (2000); Sasso, F., et al.: Metabolism, 52, 675 (2003); Kass, D., et al.: Circ. Res., 94, 1533 (2004); Murdoch, C., et al.: Cardiovasc Res., 71, 208 (2006); Hahn, M., et al.: Free Radic. Biol. Med., 28, 953 (2000); He, Z., et al.: Angew. Chem. Int. Ed., 51, 3699 (2012);<br></p>

<p>Applications 2-(5-Ethylpyridin-2-yl)prop-2-en-1-ol is a key intermediate in the synthesis of pioglitazone hydrochloride.<br>References Mohanty, S., et al.: Org. Process Res. Dev., 18, 168 (2014)<br></p>

<p>Applications 2-Chloro-4-(trifluoromethyl)pyrimidine (cas# 33034-67-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An intermediate for the synthesis of Alpidem.<br></p>

<p>Stability Moisture Sensitive, Hygroscopic<br>Applications 1,2-dimethyl-1H-imidazole-4-sulfonyl chloride (cas# 137049-02-6) is a useful research chemical.<br></p>

<p>Applications A labelled imidazole, a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);<br></p>

<p>Applications 6-bromo-5-iodopyridine-3-carboxylic acid (cas# 1200130-82-0) is a useful research chemical.<br></p>

<p>Applications N-Tosylpyrrole (cas# 17639-64-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-​Hydrazinyl-​4-​methylbenzoxazole is a useful research chemical.<br></p>

<p>Applications 6-Chloro-2,3-dimethoxypyridine (cas# 1087659-30-0) is a useful research chemical.<br></p>

<p>Applications 2-[4-(3-Pyrrolidinyl)1,3-thiazol-2yl]guanidine is a reagent which is used in biological studies as antiulcer agent.<br>References Gupta, S., et al.: J. Chem. Info. Comp. Sci, 39, 272 (1999)<br></p>

<p>Applications Pyridine-2,6-d2 (CAS# 17265-96-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Piperonyl Isobutyrate (cas# 5461-08-5) is a useful research chemical.<br></p>

<p>Applications 4,6-Dichloro-2-(methylthio)pyrimidine-5-carbonitrile (cas# 33097-13-1) is a compound useful in organic synthesis.<br></p>

<p>Applications An aromatic intermediate compound useful for the preparation of substituted melamine, ammelides, and ammelines.<br>References Sunaga, S., Bioorg. Med. Chem., 14, 4217 (2006),<br></p>

<p>Applications 2-(3,5-Dichlorophenyl)-imidazo[1,2-a]pyridine is derived from Ethyl Bromoacetate (E900140), which is used in the synthesis of metabolites of carcinogenic PAHs. Also it is used in the preparation of steroidal antiestrogens through cyclic condensation. A reactant in the preparation of antimicrobial and antioxidant coumarinyloxymethyl-thiadiazolone.<br>References Wu, A. et al.: Tetrahedron, 68, 7217 (2012); Clark, E. et al.: J. Med. Chem., 20, 1096 (1977); Al-Amiery, A. et al.: Chem. Nat. Comp., 48, 950 (2013);<br></p>

<p>Applications 1-(Phenylmethyl)-2-imidazolidinone (cas# 2385-38-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(tert-Butylamino)-4-chloro-6-cyclopropylamino-1,3,5-triazine (cas# 26737-71-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-(1H-imidazol-4-yl)propanoic acid (cas# 1074-59-5) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-N-(methyl-d3)pyridine-2-carboxamide (cas# 1189858-48-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,6-Dimethoxy-2-(methylsulfonyl)pyrimidine was used to prepare nonpeptidic endothelin-A receptor antagonists.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996); Venu, T., et al.: Bioorg. Med. Chem. Lett., 18, 4409 (2008)<br></p>

<p>Applications Tetrazolo[1,5-a]pyridin-7-amine is a chemical intermediate for the synthesis of pharmaceutical goods.<br></p>

<p>Applications 1-Phenyl-2-(4-N-Cbz-phenylamino-piperidin-1-yl)-propan-1-one (cas# 936498-12-3) is a useful research chemical.<br></p>

<p>Applications 1-Ethyl-2-piperazinone is used in the synthesis of piperidine and piperazine derivatives as cognition enhancers.<br>References Bioorg, Med. Chem., 16, 1431 (2008);<br></p>

<p>Applications 1,3-Dimethyl-2-imidazolidone, is a solvent used in various synthetic organic transformations. Studied in the formation of functionally stabilized hydrosilanediyl-transition metal complexes produced photochemically from arylsilanes.<br>References Mukaiyama, T., et al.: Chem. Lett., 1507 (1980); Seebach, D., et al.: Chem. Ber., 115, 1705 (1982);<br></p>

<p>Applications 4-Aminothieno[3,2-d]pyrimidine is a useful research intermediate<br>References Robba, M., et al.: Tetrahedron, 27, 487 (1971); Park, J. H., et al.: Heterocycles, 91, 835 (2015)<br></p>

<p>Applications An intermediate in the preparation of Pipradrol Hydrochloride<br></p>

<p>Applications Pyrrolidine-3-carboxylic acid (cas# 59378-87-9) is a useful research chemical.<br></p>

<p>Applications A product from the pyrolysis of phenylalanine.<br>References Kim, D., et al.: Bioorg. Med. Chem. Lett., 15, 2129 (2005), Che, W., et al.: Env. Toxicol. Pharmacol., 24, 11 (2007), Heitman, L., et al.: J. Med. Chem., 51, 4724 (2008),<br></p>

<p>Applications 2-Acetyl-6-bromopyridine is used in the synthesis of some embedded chalcones and pyrazoles as angiotensin converting enzyme (ACE) inhibitors.<br>References Kantevari, S. et al.: Bioorg. Med. CHem., 19, 4772 (2011);<br></p>

<p>Applications Can be used in the preparation of pyrrolylphenylsulfonates as dopamine D3 antagonists as well as in the preparation of substituted amidothiophene derivatives for use as 11-β-HSD1 inhibitors.<br></p>

<p>Applications 3-Chloro-2,5-difluoropyridine is an intermediate used to prepare selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases.<br>References Jimenez, J., et al.: J. Med. Chem., 56, 1799 (2013)<br></p>

<p>Applications Intermediate in the preparation of various enzymatic inhibitors<br>References Poeckel, D., et al.: Mol. Pharmacol., 70, 1071 (2006), Wigle, T., et al.: Bioorg. Med. Chem. Lett., 17, 3249 (2007),<br></p>

<p>Applications 3-Aminopicolinic Acid (cas# 1462-86-8) is a compound useful in organic synthesis.<br>References Dominguez, C., et al.: Bioorg. Med. Chem. Lett., 17, 6003 (2007), Stukenbrock, H., et al.: J. Med. Chem., 51, 2196 (2008),<br></p>

<p>Applications 2-(pyridin-3-yl)pyrido[2,3-d]pyrimidine has been used in the preparation of divalent transition metal aminonicotinaldehyde chloride complexes, antimicrobial, antioxidant and antitumor activities, electrochemical and molecular docking with EGFR protein.<br>References Konakanchi R., et al., Res. Chem. Intermed., 44, 27-53 (2018)<br></p>

<p>Applications 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.<br>References El-Gamal, M. I., et al.: Bull. Korean Chem. Soc., 33, 1571-1576 (2012); Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);<br></p>

<p>Applications 2-(1H-imidazol-2-yl)benzoic acid (cas# 67792-82-9) is a useful research chemical.<br></p>

<p>Applications dimethyl 4-hydroxy-1H-pyrazole-3,5-dicarboxylate (cas# 23705-85-3) is a useful research chemical.<br></p>

<p>Applications 4,4'-Diamino-2,2'-bipyridine is a bidendate chelator.<br></p>

<p>Applications DI-TERT-BUTYL 2-(HYDROXYMETHYL) PIPERAZINE-1,4-DICARBOXYLATE (cas# 143540-05-0) is a useful research chemical.<br></p>

<p>Applications 1-(cyclopropylsulfonyl)piperazine hydrochloride (cas# 1057385-13-3) is a useful research chemical.<br></p>

<p>Applications 7-(3-Bromophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (cas# 933054-30-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Amino-5-bromopyridine-2-carboxylic acid<br></p>

<p>Applications 2-Hydroxy-N-(pyridin-4-yl)butanamide is a useful synthetic intermediate.<br></p>

<p>Applications 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-Benzimidazole-2-thione is used in the preparation of triclabendazoles which are drugs used to treat liver fluke.<br>References Iddon, B., et al.:Journal of the Chemical Society 22, 3129 (1992);<br></p>

<p>Applications N-(4-Methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine (cas# 109912-28-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Reagent used in the synthesis of herbicides.<br>References Mekenyan, O., et al.: Chem. Res. Toxicol., 10, 994 (1997), Brown, T., et al.: Environ. Sci. Technol., 42, 5202 (2008),<br></p>

<p>Applications 3-(difluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (cas# 1394042-15-9) is a useful research chemical.<br></p>

<p>Applications 4-Amino-2-chloro-3-methylbenzonitrile is a reagent used in synthesis of imidazolin-2-ones, which is designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs).<br>References Li, J. J., et al.: J. Med. Chem., 50, 3015-3025 (2007)<br></p>

<p>Applications 5-(2-Pyridyl)-1,2-dihydropyridin-2-one is used in the synthesis of AMPA receptor antagonists in the treatment of neurological diseases causing dysfunction of glutamatergic neurotransmission.<br>References Hibi, S. et al.: J. Med. Chem., 55, 10584 (2012); McElhinny, C. et al.: Synthesis, 44, 57 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Bromopyrrolidine hydrobromide<br></p>