Stimulants

Applications Bromantane is an adamantane derivative used as an anxiolytic agent.
References Reznikov, A., et al.: Endokrinologie, 73, 11 (1979), Grekhova, T., et al.: Bull. Eksp. Biol. Med., 119, 302 (1995),

Applications CRL-40,941 is a wakefulness-promoting agent. It was found to produce antiaggressive effects in animals.
References Lafon, L.: US4489095 (A) (1984)

Applications Caffeidine Acid is a potential degradation product from the hydrolysis of Caffeine (C080100) under alkaline environment.
References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);

Applications Ethylphenidate Hydrochloride is the transesterification metabolite of Methylphenidate (M325880) and ethanol.
References Patrick, K.S., et al.: J. Med. Chem., 48, 2876 (2005); Naito, T., et al.: Chem. Pharma. Bull., 12, 588 (1964);

Stability Hygroscopic
Applications Fencamfamine is a CNS stimulant. This is a controlled substance (stimulant).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hotovy, R., et al.: Arzneim.-Forsch., 11, 20 (1961), DeLucia, R., et al.: Gen. Pharmacol., 21, 161 (1990), Planeta, C., et al.: Pharmacol. Biochem. Behav., 50, 35 (1995),

Applications Controlled substance. CNS stimulant. The more potent isomers of Methylphenidate. The threo enantomers have shown that the pharmacological activity residues predominantly in the d-threo enantiomer.
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981), Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

Applications Intermediate in the preparation of D-threo-Methylphenidate (Ritalin)

Applications A tobacco smoke-derived nitrosamine which is activated by multiple human cytochrome P 450s including the polymorphic human cytochrome P 4502D6.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Castonguay, A., et al.: Cancer Lett., 46, 93 (1989), Crespi, C.L., et al.: Carcinogenesis, 12, 1197 (1991),

Applications Higenamine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.
References Ha, Y. et al.: Apoptosis., 17, 463 (2012);

Applications This is a controlled substance (stimulant). Anorexic.
References Netter, P., et al.: Arzneim.-Forsch., 28, 1310 (1978); Rendic, S., et al.: Eur. J. Drug Metab. Pharmacokinet., 19, 107 (1994);

Applications The erythro isomers have been shown to exhibit very little therapeutic effect and contribute mainly to the toxic hypertensive effects of this drug.Controlled substance.
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981), Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

Applications Prolintane is a CNS stiumlant used as an analeptic drug. Prolintane acts as a norepinephrine-dopamine reuptake inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hucker, H.B. et al.: Experientia, 28, 430 (1972); Hollister, L.E. et al.: J. Clin. Pharmacol. J. New Drugs, 10, 103 (1970); Kuitunen, T. et al.: Meth. Find. Exp. Clin. Pharmacol., 6, 265 (1984):

Applications A major metabolite of Methylphenidate.
References Redalieu, E., et al.: Drug Metab. Dispos., 10, 708 (1982), Brewer, E., et al.: J. Pharm. Sci., 87, 395 (1998), Shah, V., et al.: Pharm. Res., 17, 1551 (2000), Tanaka, N., et al.: Anal. Chem., 73, 420 (2001),

Stability: Hygroscopic
Applications: (1R,2S)-Norephedrine Hydrochloride is a hydrochloride salt of (1R,2S)-Norephedrine (N674400), a metabolite of Phenmetrazine, an ephedrine alkaloid and a nervous system stimulant.
References Jian, Z., et al.: Planta Med., 54, 69 (1988);Tanaka, T., et al.: Nat. Med., 49, 418 (1995);Marchei, E., et al.: J. Pharm. Biomed. Anal., 41, 1633 (2006)

Applications: D-(-)-Pseudoephedrine, is an enantiomer of (+)-Pseudoephedrine Hydrochloride (P839350), a non-selective adrenergic agonist, used as nasal decongestant.Controlled precursor.
References Fairchild, M.D., et al.: J. Pharmacol. Exp. Ther., 158, 135 (1967); Hughes, D.T.D., et al.: J. Clin. Hosp. Pharm., 8, 315 (1983); Gurley, B.J., et al.: J. Pharm. Sci., 87, 1547 (1998);

Applications dl-threo-Ritalinic Acid Isopropyl Ester Hydrochloride is an analog of Methylphenidate (M325880), a controlled substance (stimulant). CNS stimulant.
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

Applications O-Desmethyl Methylphenidate Carboxylic Acid is a derivative of Methylphenidate Hydrochloride (M325880), controlled substance (stimulant). CNS stimulant. Methylphenidate Carboxylic Acid Hydrochloride is a 4:1 Mixture of R533105 (DL-erythro Ritalinic Acid Hydrochloride) and R533110 (DL-threo-Ritalinic Acid Hydrochloride)
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

Applications (±)-Cotinine-2,4,5,6-d4 (pyridine-d4) (CAS# 350818-68-7) is a useful isotopically labeled research compound.

Applications Sodium 4-Hydroxybutyrate-2,2,3,3-d4 (CAS# 1251763-08-2) is a useful isotopically labeled research compound.