Building Blocks

Applications 5,6,7,8-tetrahydroquinazoline-6-carboxylic acid (cas# 1369096-46-7) is a useful research chemical.

Applications 2-methyl-2-(morpholin-4-yl)propanoic Acid hydrochloride (cas# 375397-37-8) is a useful research chemical.

Stability Hygroscopic
Applications Imidazo[5,​1-​b]​thiazole-​3-​carboxylic Acid Hydrochloride is a useful research chemical.

Applications 6-Fluoro-4-methyl-2-pyridinamine can be synthesized from 2,6-Dichloro-4-methylpyridine (39621-00-6).

Applications 2,3,5,6-Tetramethylpyrazolo[1,2-a]pyrazole-1,7-dione (cas# 68654-22-8) is a compound useful in organic synthesis.

Applications A useful synthetic intermediate.

Applications 1-Ethyl-3-piperidinone Hydrochloride used in preparation of Aminoimidazoles.
References Sabbasani, Venkata R., et al.: Angewandte Chemie, 58, 18913-18917 (2019);

Applications Tetramethyl-d12-urea (CAS# 51219-89-7) is a useful isotopically labeled research compound.

Applications 4-Fluoro-3-nitrobenzoic Acid (cas# 453-71-4) is a compound useful in organic synthesis.

Applications 2-Fluoro-5-nitrobenzoic Acid (cas# 7304-32-7) is a compound useful in organic synthesis.

Applications 6-Fluoronicotinic acid

Applications 1,2,3-Trichloropropane-d5 (CAS# 203578-27-2) is a useful isotopically labeled research compound.

Applications Labelled Malonamide (M158000). Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.
References Katagi T., et al.: Chem. Pharm. Bull., 33, 4878 (1985),

Applications Glyceryl Tri(octanoate-d15) (CAS# 352431-24-4) is a useful isotopically labeled research compound.

Applications Trichloroacetyl Isocyanate is used as an in situ derivatizing reagent for characterization of alcohols, glycols, phenols, and amines by nuclear magnetic resonance (NMR).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bose, A.K., et al.: Tetrahedron, 31, 3025 (1975); Goodlett, V.W.: Anal. Chem., 37, 431 (1965); Stokker, G.: J. Org. Chem., 48, 2613 (1983)

Applications Trichloroisocyanuric Acid is a disinfectant and anti-bacterial. It can also be used in the synthesis of napthols.
References Yang, L.: J. Chem., 9, 2424 (2012); Chaidez, C. et al.: Int. J. Environ. Health Res., 13, 295 (2003);

Stability Volatile
Applications 1,1,1-Trifluoroacetone is a general chemical reagent used in the synthesis of glucokinase-glucokinase regulatory protein) GK-GKRP disruptors which may act as potential targets for type II diabetics. Reactant for enantioselective cycloadditions.
References Nishimura, N. et al.: J. Med. Chem., 57, 3094 (2014); Davies, A. et al.: Chem. A Eur. J., 21, 18944 (2015);

Applications 1,2,4-Triazin-3-amine can be used as integrade inhibiting antiviral agents.
References Kiyama, R., et.al.: PCT Int. Appl.WO 2003016275 A1, 663, (2003);

Applications 3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine (cas# 706757-05-3) is a useful research chemical.

Applications Glyceryl Tri(dodecanoate-11,11,12,12,12-d5) (CAS# 1219805-25-0) is a useful isotopically labeled research compound.

Applications (3,4,5-Trimethoxyphenyl)acetic-alpha,alpha-d2 Acid (CAS# 344299-45-2) is a useful isotopically labeled research compound.

Applications 2,4,6-Triisopropylbenzenesulfonyl Azide is a useful synthetic intermediate. It is used in the synthesis of Antidote to anthrax lethal factor intoxication, bacterial RNA polymerase inhibitors and bicyclic extended dipeptide surrogates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, S., et al.: Bioorg. Med. Chem. Lett., 21, 2030 (2010); Pronin, S., et al.: J. Am. Chem. Soc., 132, 14394 (2010); Ranatunga, S., et al.: J. Org. Chem., 75, 5113 (2010)

Applications Tetrahydropyran-2-methanol (cas# 100-72-1) is a useful research chemical.

Applications 2,4,6-Triisopropylbenzenesulfonyl Chloride, is a building block used for the synthesis of various pharmaceutical compounds, such as derivatives of Valproic Acid (V094750). It can also be used for the synthesis of glycerophospholipids as a condensing agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Aneja, R., et al.: Biochimica et Biophysica Acta, 218, 102 (1970); Loscher, W., Prog. Neurobiol., 58, 31 (1999);

Applications 2-Iodo-2-methylpropane-d9 (CAS# 61207-61-2) is a useful isotopically labeled research compound.

Applications 5-(Trifluoromethyl)indolin-2-one is a useful reagent for the preparation of 3-Chloro-α-carbolines.
References Tian, S., et al.: Synlett, 29, 949 (2018)

Applications 1,2-Dimethoxybenzene-d10 (CAS# 362049-43-2) is a useful isotopically labeled research compound.

Applications 1,2-Dimethoxybenzene-4,5-d2 (CAS# 203645-56-1) is a useful isotopically labeled research compound.

Applications 2-Chloro-3-nitropyridine (cas# 5470-18-8) is a useful research chemical.

Applications Isotope labelled analog of N-Nitrosobis(2-hydroxypropyl)amine (N525225), a compound that exhibits carcinogenicity in duct cells.
References Chang, P., et al.: Environ. Mol. Mutagen, 41, 43 (2003), Prohaska, J., et al.: Exp. Biol. Med., 228, 959 (2003), Abe, K., et al.: Biomed. Res., 26, 187 (2005), Abe, M., et al.: J. Toxicol. Pathol., 19, 129 (2006),

Applications Heterocyclic compound used in cosmetic compositions.
References Windheuser, J., et al.: J. Pharm. Sci., 71, 121 (1982), Davis, E., et al.: J. Med. Entomol., 22, 237 (1985), Osimitz, T., et al.: J. Toxicol., 35, 435 (1997), Ross, E., et al.: Drug Metab. Dispos., 32, 783 (2004),

Applications 1,2,3,4-Cyclobutanetetracarboxylic Acid is a reagent used in the preparation of cobalt cyclobutanetetracarboxylate polymer.
References Diaz-Gallifa, P., et al.: Inorg.Chem., 53, 5674 (2014)

Applications Isobutyryl chloride is a useful intermediate commonly used in synthetic chemistry. Isobutyryl chloride is also a potential inducer of pulmonary adenomas in strain A mice.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Theiss, J., et al.: Cancer Res., 39, 391 (1979)

Applications (1R,2R)-rel-trans-1,2-Cyclopentanediol is a building block for the synthesis of chiral phosphine ligands. It can also be used to prepare benzoquinolines and benzoindoles via heterocyclization of naphthylamines with diols catalyzed by iridium chloride/BINAP
References Kündig, E., et al.: Helv. Chim. Acta, 77, 421 (1994); Aramoto, H., et al.: J. Org. Chem., 74, 628 (2009)

Applications 4-Cyano-4'-n-pentyl-d11-biphenyl (CAS# 57078-20-3) is a useful isotopically labeled research compound.

Applications 2-Hydroxyimino-3-pentanone is an intermediate in the preparation of indole derivatives.
References Goya, P., et al.: J. Med. Chem., 35, 3977 (1992), Masaguer, C., et al.: Chem. Pharm. Bull., 47, 621 (1999), Wu, S., et al.: Bioorg. Med. Chem. Lett., 16, 5859 (2006),

Applications Cyclopentylamine is a useful synthetic intermediate. It was used to prepare chiral N-aminoacyl pyrrolidines and (adamantylamino)acetamides as selective and orally bioavailable dipeptidyl peptidase IV inhibitors with antihyperglycemic properties. It is also a reagent used to prepare dipeptidyl peptidase IV inhibitors as potent anti-diabetic agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Villhauer, E., et al.: J. Med. Chem., 46, 2774 (2003); Ahn, J., et al.: Bioorg. Med. Chem. Lett., 14, 4461 (2004)

Applications 2-Ethyl-d5-toluene is a useful isotopically labeled compound of 2-Ethyl Toluene (E926634)

Applications 2-​Aminoindan-​2-​carboxylic Acid can be used as a potential tyrosine hydroxylase inhibitor.
References Pinder, R., et al.: J. Med. Chem., 14, 892 (1971)

Applications Intermediate in the production of Isosafrole and Ethylone.
References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),

Applications N-Methyl-d3-form-d1-amide (CAS# 110505-55-0) is a useful isotopically labeled research compound.

Applications Ethyl-1,1-d2 Alcohol-OD (CAS# 22544-42-9) is a useful isotopically labeled research compound.

Applications 3,4-(Methylenedioxy)phenylacetic Acid (cas# 2861-28-1) is a compound useful in organic synthesis.
References Perez-Medrano, A., et al.: J. Med. Chem., 52, 3366 (2009), Moon, J., et al.: Bioorg. Med. Chem. Lett., 20, 734 (2010),

Applications N,N'-Bis(2-aminoethyl)-1,3-propanediamine-d20 is a useful isotopically labeled compound of N,N'-Bis(2-aminoethyl)-1,3-propanediamine (N497323)

Applications Methylboronic Acid is a methylated derivative of boronic acid, a building block towards various intermediates in suzuki coupling.
References Baker, J. O., et al.: Biochem.. 22, 2098 (1983); Garner, C.W., et al.: J. Biol. Chem., 255, 5064 (1980)

Applications (2,4-Dioxo-thiazolidin-3-yl)-acetic Acid is a useful compound for preparation of novel thiazolidinedione-​hydroxamates as Zmp1 inhibitors.
References Slachtova, V., et al.: Eur. J. Med. Chem., 185, 111812 (2020)

Applications 1-Phenyldodecane-d30 (CAS# 352431-29-9) is a useful isotopically labeled research compound.

Applications 2,4-Dichlorotoluene-3,5,6-d3 (CAS# 1398065-47-8) is a useful isotopically labeled research compound.

Applications 1-(2-Methylpropyl)-4-piperidone had potential use in the manufacturing of medicament for promoting bone regrowth and repair.

Applications Methyl 2-Formyl-3-hydroxybenzoate can be used to treat sickle cell disease.
References Metcalf, B.W., et.al.: PCT Int. Appl. WO 2020072377 A1, 146, (2020);

Applications 4'-Methoxypropiophenone (cas# 121-97-1) is a compound useful in organic synthesis.
References Smith, H., et al.: Med. Chem., 3, 135 (2007), Trogden, B., et al.: Bioorg. Med. Chem. Lett., 19, 485 (2009),

Applications Dehydroacetic Acid Sodium is used as a food additive, preservative, and antimicrobial agent.
References Sakaguchi, Y., et. al.: J. Appl. Toxicol., 28, 524 (2008); Sipes, N.S., et. al.: Chem. Res. Toxicol., 26, 878 (2013);

Applications N-Methyl-d3-glycine-2,2-d2 HCl (CAS# 1219794-62-3) is a useful isotopically labeled research compound.

Applications Methyl 2-Cyclopentanonecarboxylate is used in the synthesis of functionalized ketones.
References Mashima, K. et al.: J. Org. Chem., 59, 3064 (1994); Hamashima, Y. et al.: J. Am. Chem. Soc., 124, 11240 (2002);

Applications 2-Amino-6-methoxybenzothiazole is an intermediate used to prepare novel series of Schiff bases and 4-thiazolidinones. It is also used in the synthesis of 2-cyano-6-methoxybenzothiazole.
References Patel, N., et al.: Saudi Pharma. J., 18, 129 (2010); Toya, Y., et al.: Bull. Chem. Soc. Jpn., 65, 392 (1992)

Applications Ethyl-1-d1 Alcohol (CAS# 1624-36-8) is a useful isotopically labeled research compound.

Applications 4-Isopropylphenylacetic acid (cas# 4476-28-2) is a useful research chemical.

Applications 1,2-Dibromobenzene-d4 (CAS# 1643577-34-7) is a useful isotopically labeled research compound.

Applications Malonic Acid-2-13C is labelled Malonic Acid (M158005) which is a small bioactive molecule, that can be used in variuos reactions. It is the classic example of a competitive inhibitor, which acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.
References Weiner, N., "Malonic acid", Org. Synth.; Coll. Vol. 2: 376;

Applications 1,6-Dibromohexane-d12 (CAS# 169397-96-0) is a useful isotopically labeled research compound.

Applications 1,5-Dibromopentane is used as an alkylating agent in organic synthesis. 1,5-Dibromopentane is also used as a reagent to synthesize benzo[b]xanthone derivatives, compounds that have potential anticancer activity.
References Luo, L., et al.: J. Serb. Chem. Soc., 78, 1301 (2013); Royer, G. & Klotz, I.: J. Am. Chem. Soc., 91, 5885 (1969)

Applications Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.
References Mazzocchi, P., et al.: J. Am. Chem. Soc., 106, 7567 (1984); Villagran, C., et al.: Ultrasonics Sonochemistry, 12, 423 (2005)

Applications 1,5-Dibromopentane-d10 (CAS# 1219802-90-0) is a useful isotopically labeled research compound.

Applications (E)-2-Heptylidenecyclopentanone, is a common substance that is found in fragrances.

Applications 1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty.
References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 695 (1974);

Applications B-1-Naphthalenyl-boronic Acid is a useful synthetic intermediate. It is a reagent used to synthesize potassium aryltrifluoroborates which is a convenient precursor of arylboron difluoride lewis acids. It can also be used to prepare high yields of biaryls via Suzuki coupling.
References Vedejs, E., et al.: J. Org. Chem., 60, 3020 (1995); Larhed, M., et al.: Tetrahedron Lett., 37, 8219 (1996); Singh, R., et al.: 7, 1829 (2005)

Stability Moisture Sensitive
Applications 3,4-Dimethoxybenzoyl Chloride is a benzoyl chloride derivative used in the preparation of a variety of biologically active compounds such as bronchodilators
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sharma, R.L. et al.: ARKIVOC, 10, 233 (2009);

Applications alpha,alpha'-Dibromo-p-xylene-d8 (CAS# 74903-77-8) is a useful isotopically labeled research compound.

Applications 1,3-Dibromo-5-fluorobenzene-d3 (CAS# 1219805-87-4) is a useful isotopically labeled research compound.