Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Pyridin-2-yloxy)aniline is a synthetic compound that is used as a potent inhibitor of the enzyme tyrosine hydroxylase. This enzyme catalyzes the conversion of tyrosine to L-3,4-dihydroxyphenylalanine and plays a key role in the synthesis of dopamine. 3-(Pyridin-2-yloxy)aniline has been shown to be effective in treating Parkinson's disease and other disorders that involve neuronal degeneration and cell death. This drug inhibits the production of dopamine by binding to tyrosine hydroxylase, thereby preventing it from converting tyrosine into L-3,4-dihydroxyphenylalanine. The compound also has significant inhibitory activity against cyclin dependent kinases (CDKs), which are enzymes that regulate the activity of protein kinases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzothiophene-6-carboxylic acid is a nicotinic acetylcholine receptor agonist that has been shown to have high oral bioavailability and efficacy in vivo. It binds to the α7 nicotinic acetylcholine receptor and activates the receptor, leading to increased neurotransmitter release. 1-Benzothiophene-6-carboxylic acid has been shown to be effective in vivo in models of neuropathic pain and Parkinson's disease. This drug also has a low affinity for other receptors, such as muscarinic acetylcholine receptors, which reduces the chance of adverse effects.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-4H,5H-naphtho[2,1-b]thiophene-1-carbonitrile is a dihydronaphthalene compound that has been shown to be active against influenza viruses. It inhibits the virus by binding to the pyrimidine ring of the virus's RNA polymerase. This inhibits viral replication and reduces plaque formation. 2-Amino-4H,5H-naphtho[2,1-b]thiophene-1-carbonitrile has antiviral activity against influenza A and is effective in inhibiting h5n1 virus replication.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Vinylnicotinic acid methyl ester belongs to the group of antimicrobial agents. It is a chemical compound that has been shown to be effective against cervical cancer and may have potential as an anticancer drug. 5-Vinylnicotinic acid methyl ester inhibits the growth of human chorionic gonadotropin (HCG) in women, which is a hormone necessary for ovulation and pregnancy. This compound also inhibits the growth of viruses, such as herpes simplex virus type 1 (HSV-1), and bacteria, such as dittrichia sp., which causes inflammation of the throat. 5-Vinylnicotinic acid methyl ester has also been shown to inhibit protein synthesis in human osteosarcoma cells at low concentrations, but not at high concentrations.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-3-methoxy-6-nitroaniline is a chemical compound that has been shown to have antimicrobial and anti-HIV activities. It is active against various bacteria, including methicillin resistant Staphylococcus aureus (MRSA). 2-Chloro-3-methoxy-6-nitroaniline has also been shown to have cytotoxic effects on MT4 cells, which are human lymphocytes. This drug may be useful as an HIV inhibitor because of its ability to inhibit HIV's reverse transcriptase enzyme activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,6,7-Trichloroquinoline is an anticancer drug that was first synthesized in the late 1950s. It is a type of 1,2-dihydroquinoline that has been modified by the addition of three chlorine groups. 4,6,7-Trichloroquinoline inhibits the growth of cancer cells by inducing DNA strand breaks and inhibiting DNA synthesis and protein synthesis. This drug also induces cell death through the release of reactive oxygen species. 4,6,7-Trichloroquinoline binds to tumor cells and inhibits their proliferation by binding to DNA molecules and preventing them from replicating. The hydrolysis process for this compound occurs in two steps: first it is hydrolyzed into diethylmalonate and ethoxymethylenemalonate; then it undergoes cyclization with condensation and decarboxylation to form a quinolinium salt.</p>

<p>Versatile small molecule scaffold</p>

<p>Tert-butyl (2S)-2-aminohexanoate is an intermediate that is used in the synthesis of glycine by the reaction of benzyl bromide and tert-butyl amine. The stereospecifically incorporated tert-butyl group has a high degree of enantioselectivity, which makes this intermediate useful in the synthesis of glycine. Tert-butyl (2S)-2-aminohexanoate can be synthesized using lithium diisopropylamide and a tertiary amine as an alkylating agent.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Iodoethyl)-2,3-dihydro-1H-isoindole-1,3-dione is a crystalline compound that is an n-substituted derivative of phthalimide. It has been shown to be effective for the treatment of tuberculosis. This drug binds to DNA and inhibits transcription and replication. 2-(2-Iodoethyl)-2,3-dihydro-1H-isoindole-1,3-dione also inhibits bacterial growth by binding to RNA polymerase.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>