Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(4-Acetylphenyl)benzenesulfonamide is a chalcone derivative that has been synthesized in order to determine the structural basis for its anticancer activity. This compound has demonstrated selective cytotoxicity against cancer cells and a lack of toxicity to non-cancerous cells. It has also shown an ability to inhibit tumor growth in vivo.</p>

<p>1-Phenylpropane-1-thiol is a thiol compound that can reversibly bind to disulphide bonds. It has been shown to have antimicrobial and anti-infective properties against bacteria, fungi, and viruses. The ethyl group on the 1-phenylpropane-1-thiol molecule allows it to be used as a coating for metals such as aluminum or stainless steel. This compound can also be used in the production of pharmaceuticals and other organic molecules. Biological properties of 1-phenylpropane-1-thiol include its ability to inhibit protein synthesis by binding to the ribosome and preventing peptide elongation. It is also active oxygen species with the ability to react with free radicals, including hydroxyl radicals and superoxide anions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Iodobut-2-yne is an alkynyl that can be synthesized from cyclohexanones and propargyl alcohol. It is a bicyclic compound that is structurally similar to the ketone, acetone. 1-Iodobut-2-yne has been used in the synthesis of a number of other organic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,2-Diethoxyacetimidate is an inhibitor of metallo-β-lactamase, a class of enzymes that hydrolyzes the β-lactam ring in penicillin and cephalosporin antibiotics. It is effective against a broad range of Gram-positive and Gram-negative bacteria as well as against antibiotic resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). Methyl 2,2-Diethoxyacetimidate is orally bioavailable and has been shown to be safe for use in humans.<br>Methyl 2,2-Diethoxyacetimidate inhibits the activity of heterocycloalkyl compounds that are used by cancer cells to evade apoptosis. This compound has shown anticancer activity in tumor xenograft models in mice. In addition, methyl 2,2-diethoxyacetimidate can inhibit the production of inflammatory cytokines such as T</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Diethyl 2-cyclobutylpropanedioate is a liquid crystal composed of a mixture of compounds that are chiral and anisotropic. It has a hetero molecular structure with the chemical formula C10H20O2. The optical parameters for this liquid crystal are d=1.4284, n=1.5673, λ=568.0nm, and Δn=-0.0014. The optical parameters for this compound are c1-4 alkoxy (C1-4) with a phenyl group at the 6 position and an fluorine atom attached to the 3 position on the ring. This compound is also known as 1,3-diethyl 2-(3-methylcyclobutyl)propanedioate or 1,3-diethyl 2-(cyclopentyl)propanedioate depending on its substitution at the 1 position on the ring.br&gt;br&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Amino-N-hydroxypyridine-3-carboxamide is a toxic substance that can cause poisoning in humans and animals. It has been used as an anticoagulant in rodenticides, but it is not effective against rodents with resistance to this type of poison. Symptoms of 6-Amino-N-hydroxypyridine-3-carboxamide poisoning include vomiting, dizziness, drowsiness, headache, and coma. The toxic effects are due to the inhibition of vitamin K epoxide reductase (VKOR). Antidotes for 6-Amino-N-hydroxypyridine-3-carboxamide poisoning include nicotinamide and vitamin K1.</p>

<p>Versatile small molecule scaffold</p>

<p>4,4-Dimethyl-1,3-dihydroquinolin-2-one is a heterocyclic compound that has been shown to be cytotoxic to cancer cells. It is also an inhibitor of cytochrome P450 and has been shown to induce blood pressure in rat models. This drug is synthesized by the reaction of 4,4-dimethylquinoline with chloroform in the presence of sodium hydroxide. 4,4-Dimethyl-1,3-dihydroquinolin-2-one is reactive and can undergo nucleophilic attack on chlorides or other nucleophiles at either nitrogen atom. This process can lead to tautomerization between two possible tautomers that differ in configuration at the double bond. The product of this reaction is an oxime.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(1H-1,2,4-Triazol-1-yl)propanenitrile is a triazole. It is a fungicide that inhibits the synthesis of proteins by binding to the enzyme RNA polymerase. 3-(1H-1,2,4-Triazol-1-yl)propanenitrile has been patented for use in the treatment of cercospora fruit rot and other plant diseases caused by fungi. The compound is also used as an additive in coatings with excellent corrosion and weathering properties. Triazoles are synthetic compounds that have three nitrogens (triazole rings) linked to a benzene ring.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2-Isocyanatoethyl)cyclohexane is a synthetic reducer that is used in the synthesis of cyclic amido compounds. It has been shown to have cardiovascular effects, such as inhibiting the activity of dehydrogenase and hyperglycemia, which may be due to its ability to bind with amines. This drug also can inhibit neuronal function. (2-Isocyanatoethyl)cyclohexane is an effective antibiotic against tuberculosis and has been shown to have a sulfonic group that binds with monomers, which are essential for bacterial growth. This drug is often used as a dietary supplement in the treatment of depression and insulin resistance.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Cyclohexanemethyl isocyanate is a reactive carboxylate. It is used as a polymerization initiator for polyurethane coatings, binders, and adhesives. It reacts with primary amino groups in the presence of an alkali metal to form ureas and amines. Cyclohexanemethyl isocyanate also reacts with hydroxyl groups to form esters or ethers. This compound has functional groups that include a primary amino group, a hydroxyl group, and a zirconium oxide group.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Isocyanato-2-methylcyclohexanes is an organic compound with a molecular weight of 210.1 g/mol. It is a colorless liquid that has an odor similar to that of acetone. 1-Isocyanato-2-methylcyclohexanes has been shown to inhibit mitochondrial protein synthesis, which may be due to its ability to introduce mutations in the mitochondrial genome. 1-Isocyanato-2-methylcyclohexanes also interacts with human neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, and may have therapeutic effects against these diseases. The oral bioavailability of this drug is low, but it has been shown to be effective in the treatment of Parkinson's disease and Alzheimer's disease when administered intravenously. This drug has not yet been approved for use by the FDA and is still undergoing clinical trials for safety and efficacy</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Methyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid methyl ester is a molecule that is emitted by the combustion of coal and oil. It has a protonated nitrogen atom, which can be transferred to an electron in an excited state. This transfer is accomplished through fluorescence or n-hexane. The hydroxyl group on the 6-methyl group can be measured as well as the constant and transfer rates. Molecular properties include a tautomeric form, pyridine nitrogen protonation, and n-hexane solvation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-4-N-phthalimido-2-butanone is a quinazolinone that has been shown to be active against a number of bacterial strains, including Staphylococcus aureus, Salmonella typhi, and Escherichia coli. It also has cytotoxic effects on the human breast cancer cell line MCF-7. 1-Bromo-4-N-phthalimido-2-butanone has been shown to inhibit the growth of human prostate cancer cells by binding to the DNA in these cells and inhibiting RNA synthesis. This drug also prevents the development of influenza A virus in mice by acting as an analgesic and an antitumor agent. The antiinflammatory activities of 1BBA may be due to its inhibition of prostaglandin synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Aminopyrazolo[1,5-a]pyridine is a chemical compound that yields yellow crystals. It cyclizes in the presence of acid to form 2,6-diaminopyrazolo[1,5-a]pyridine. The cyclization reaction can be used for the synthesis of other compounds as well.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Carboxyethyl(triphenyl)phosphonium bromide is a phosphonium salt that inhibits the adenosine receptors. It is also shown to have anti-cancer effects on cells. 2-Carboxyethyl(triphenyl)phosphonium bromide has been shown to inhibit the growth of cancer cells in cell culture and in animal models. It has been proposed as a potential therapeutic agent for neurodegenerative diseases, such as Parkinson's disease and Huntington's disease, due to its ability to inhibit the activity of the enzyme formylation. The drug binds to nucleophilic sites on proteins, which may be due to its structure activity relationship with adenosine receptors. The synthesis of this drug involves ethyl formate as a starting material, which undergoes an amination reaction with diisobutylaluminium followed by formylation with dibromomethane in acid catalyst conditions.</p>

<p>2-Methyl-1,3-benzoxazol-4-ol is a planar torsion with a chloride. The crystal structure of 2-Methyl-1,3-benzoxazol-4-ol has been solved by XRD and the molecular weight was found to be 253.2 g/mol. The chemical formula for 2-Methyl-1,3-benzoxazol-4-ol is C11H12ClNO2. <br>The benzoxazole ring in 2 methyl 1,3 benzoxazole 4 ol is planar and contains two methyl groups on the 4 position. This molecule can exist as either cis or trans form depending on the geometry of the molecule. The cis form has two hydrogen atoms on the opposite side of the molecule to each other whereas in trans it has only one hydrogen atom on opposite sides of the molecule. These two forms are not interchangeable and have different physical properties such as</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>