Building Blocks

<p>Applications 10-Undecen-1-ol (cas# 112-43-6) is a useful research chemical.<br></p>

<p>Applications DL-Leucine-d10-N-FMOC is a useful isotopically labeled compound<br></p>

<p>Applications DL-Leucine-d10 (CAS# 29909-01-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-Leucine-2-d1 (CAS# 89836-93-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-Leucine-3,3-d2 (CAS# 362049-59-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Leucic Acid is an intermediate used to prepare aryl-substituted indazole derivatives as modulators and inhibitors of protein kinases in the treatment of tumor growth, cellular proliferation, and angiogenesis.<br>References Kania, R., et al.: PCT Int. Appl., WO 2001002369 A2 20010111 (2001)<br></p>

<p>Stability Hygroscopic<br>Applications 3-Bromo-1-(trimethylsilyl)-1-propyne is a reactant used in the preparation of a novel lipid mediator with anti-inflammatory activity. Also used in the preparation of (+)-Rubriflordilactone A, a natural nortriterpenoid.<br>References Goto, T. et al.: Tetrahedron., 71, 8320 (2015); Goh, S. et al.: Angew. Chem. Int. Ed., 54, 12618 (2015);<br></p>

<p>Applications 2-Cyclopropylethyl-1,1,2,2-d4-amine (CAS# 1219795-00-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methylacetamide-N-d1 (CAS# 3669-70-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methyl-d3-acetamide (CAS# 3669-71-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methylacetamide-2,2,2-d3 (CAS# 3669-69-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-Bromo-1-pentene (cas# 1119-51-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Thymine-alpha,alpha,alpha,6-d4 Glycol (mixture of diastereomers) (CAS# 132523-94-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentane-4,4,5,5,5-d5 (CAS# 83418-34-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentane-1-d1 (CAS# 148404-92-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-(3-Methylbutyryl)glycine-2,2-d2 (CAS# 1219795-09-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications B-1-Naphthalenyl-boronic Acid is a useful synthetic intermediate. It is a reagent used to synthesize potassium aryltrifluoroborates which is a convenient precursor of arylboron difluoride lewis acids. It can also be used to prepare high yields of biaryls via Suzuki coupling.<br>References Vedejs, E., et al.: J. Org. Chem., 60, 3020 (1995); Larhed, M., et al.: Tetrahedron Lett., 37, 8219 (1996); Singh, R., et al.: 7, 1829 (2005)<br></p>

<p>Applications 1-Bromopentane-1,1-d2 (CAS# 77734-75-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentane is a chemical reagent used in a multitude of organic syntheses. It is used iron-catalyzed alkylations of aromatic Grignard reagents via cross coupling. It is used in the synthesis of α,γ-diketo acids as reversible inhibitors of Hepatitis C virus NS5b RNA polymerase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cahiez, G. et al.: Angew. Chem. Int. Ed., 46, 4364 (2007); Summa, V. et al.: J. Med. Chem., 47, 14 (2004);<br></p>

<p>Applications 1-Bromopentane-1,1,2,2-d4 (CAS# 1219803-61-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentane-5,5,5-d3 (CAS# 75736-50-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Bromo-2-nitroaniline is used for the synthesis of reagents such as ethyltriphenylphosphonium tribromide;<br>References Jamir, L., et al.: Synthetic. Comm., 41, 147 (2011); Reuter, R., et al.: Euro. J. Org. Chem., 32, 5647 (2009);<br></p>

<p>Applications 1-Aminonaphthalene-d9 (CAS# 78832-56-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Benzene-1,4-d2 (CAS# 1684-46-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 6-Heptynoic Acid is used as a reagent in organic synthesis, inlcuding that of some novel triazole derivatives which display antiproliferative activity and also of acetylenic fatty acids and their esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pertino, M., et al.: Molecules, 19, 2523 (2014); Nakatani, M., et al.: B. Chem. Soc. Jpn., 59, 3535 (1986);<br></p>

<p>Applications 3-​Methylbutyryl-​d9 Chloride is an intermediate for the synthesis of Isovaleryl L-Carnitine-d9 Chloride (I917582), which is labelled Isovaleryl L-Carnitine Chloride (I917580), and it is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>

<p>Applications 1-Naphthalenemethanol (cas# 4780-79-4) is a useful research chemical.<br></p>

<p>Applications Quinoxaline-5,6,7,8-d4 (CAS# 64252-08-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.<br>References Sun, L. et al.: Cell, 148, 213 (2012);<br></p>

<p>Applications p-Xylene-d4 (ring-d4) (CAS# 16034-43-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,1,1-Trifluoro-2-iodoethane (cas# 353-83-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Nefiracetam improves post-ischemia evoke-nonconvulsive seizure by altering pro-inflammatory cytokines.<br>References Fu, C. et al: Cell. Phys. Biochem., 37, 2023 (2015);<br></p>

<p>Applications ethyl (4-aminophenyl)carbamate (cas# 57399-97-0) is a useful research chemical.<br></p>

<p>Applications Undecanoic-11,11,11-d3 Acid (CAS# 1219802-11-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Undecanoic-2,2-d2 Acid (CAS# 64118-43-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isophytol was used to study the acidities and acidity-catalytic activity relationships for sulfonic acid-functionalized ionic liquids with pyridinium cations.Regioselective condesation of trimethylhydroquinone with isophytol produced (±)​-​α-​tocopherol (vitamin E; Tf= CF3SO2)​.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xing, H., et al.: J. Mol. Catal. A: Chem., 264, 53 (2007); Hasegawa, A., Angew. Chem. Int. Ed., 42, 5731 (2003).<br></p>

<p>Applications 1-Bromopentadecane-d31 (CAS# 349553-93-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromopentadecane-1-13C is a useful isotopically labeled compound of 1-Bromopentadecane (B686155)<br></p>

<p>Applications 3-Isopropylbenzoic acid<br></p>

<p>Applications 4-Nitrobenzeneazomalononitrile (cas# 1080-02-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,10-Phenanthroline-d8 (CAS# 90412-47-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Nitrobenzenemethanol is a potential building block in the synthesis of various pharmaceuticals.<br>References Misra, K., et al.: J. Molec. Catalys. Enzymatic., 82, 92 (2012); Ashauer, R., et al.: Environ. Sci. Technol., 46, 4682 (2012);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Nitrobenzenesulfonyl Chloride is used in the preparation of N-Nosyl-α-amino acid for peptide synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leggio, A. et al.: Tetrahedron, 63, 8164 (2007); Di Gioia, M.L. et al.: J. Org. Chem., 68, 7416 (2003);<br></p>

<p>Applications A protein advanced glycosylation inhibitor.<br>References Cantrell, C., et al.: J. Agric. Food Chem., 53, 5948 (2005), Jaenson, T., et al.: J. Med. Entomol., 43, 731 (2006),<br></p>

<p>Applications 4-Nitrobenzyl Bromide is used in the synthesis of di and tri-substituted azoles. Also used in the preparation of N6-Benzyladenosine-5’-uronamides as selective A3 adenosine agonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gallo-Rodriguez, C. et al.: J. Med. Chem., 37, 636 (1994); Appukkuttan, P. et al.: Org. Lett., 6, 23 (4223);<br></p>

<p>Applications 4-Bromophenetole is a non-irritant used to verify ocular irritability tests.<br>References Abraham, M., et al.: Toxicol. Sci., 76, 384 (2003); Cruz-Monteagudo, M., et al.: B. Math. Bio., 68, 1555 (2006)<br></p>

<p>Applications 5-Bromovaleric Acid used in the synthesis of inhibitors for aminoglycoside resistant bacteria. Also used in the preparation of sequence specific base pair mimics as topoisomerase IB inhibitors.<br>References Vong, K. et al.: ACS Chem. Biol., 7, 470 (2012); Vekhoff, P. et al.: Biochem., 52, 43 (2012);<br></p>

<p>Applications 4-Nitrobiphenyl-d9 (CAS# 350818-59-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-​Bromopentyl Acetate is used to model the toxicity of haloesters on marine bacterium such as Vibrio fischeri.<br>References Cornin, M.T.D, et. al.: SAR QSAR Environ. Res., 11, 301 (2000)<br></p>

<p>Applications 3-Chlorotoluene-2,4,6-d3 (CAS# 1219803-79-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Chlorotoluene-d7 (CAS# 1219804-88-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromonaphthalen-2-ol<br></p>

<p>Applications 2-Chloro-1,1,1-trimethoxyethanen is a reactant in the synthesis of α-chloro-β-aminosulfinyl imidates as chiral building blocks<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Col0paert, F., et. al.: J. Org. Chem., 76, 2204 (2011)<br></p>

<p>Applications Nitroethane-d5 (CAS# 57817-88-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Chlorotoluene-2,3,5,6-d4 (CAS# 85577-24-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications TRIS Maleate-d15 (CAS# 1219806-43-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Bromonaphthalene<br></p>

<p>Applications m-Nitrobenzoic Acid is a reagent used in the coupling of allyl acetate to allylic, aliphatic and benzylic alcohols. It is also used as a chemoattractant against Pseudomonas strains.<br>References Parales, R.: App. Environ. Microbiol., 70, 285 (2004); Kim, I. et al.: J. Am. Chem. Soc., 8, 1378 (2008);<br></p>

<p>Applications 2-Bromo-4'-methoxyacetophenone is a α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.<br>References Taylor, W., et al.: Bioorg. Med. Chem., 4, 1515 (1996), Elchelby, M., et al.: Science, 283, 1544 (1999), Shen, K., et al.: J. Biol. Chem., 276, 47311 (2001), Wang, P., et al.: Biochemistry, 41, 6202 (2002),<br></p>

<p>Applications Tri-iso-propyl-d21-phosphine Carbon Disulfide Complex (CAS# 1219798-41-0) is a useful isotopically labeled research compound.<br></p>

<p>Stability Moisture Sensitive<br>Applications Propylphosphonic Anhydride is used to prepare aryloxybenzylmorpholines as dual serotonin and noradrenaline reuptake inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fish, P., et al.: Bioorg. Med. Chem. Lett., 18, 2562 (2008)<br></p>

<p>Applications 4-Chlorotoluene-d7 (CAS# 84344-06-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5alpha-Cholestane-3,3-d2 (CAS# 122241-86-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Choline-d13 Bromide (cas# 203645-64-1) is a useful research chemical.<br></p>

<p>Applications Hydrocinnamic-alpha,alpha-d2 Acid (CAS# 19136-97-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Phenoxy-2-propanone is a general chemical reagent used in the preparation of α-arylthio ketones via DL-proline.<br>References Vaquer, A. et al.: RSC Adv. 5, 96695 (2015);<br></p>

<p>Applications 2-Chloro-3-hydroxybenzoic acid (cas# 51786-10-8) is a useful research chemical.<br></p>

<p>Applications 2-Chloro-3-nitropyridine (cas# 5470-18-8) is a useful research chemical.<br></p>