Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>5-Methyl-N-{6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl}-6-(trifluoromethyl)-2,3-dihydro-1H-indole-1-carboxamide dihydrochloride is a serotonin receptor antagonist. It is structurally related to the prototypical 5HT2CR agonist, 8-(3-(4-(2,5-dimethoxyphenyl)-1-[1,2,4]triazol--5-- yl)phenoxy)octanoic acid (8OCPA). This drug has been shown to be an effective and selective 5HT2CR antagonist in animal studies. 5HT2CR antagonists have been shown to be effective in treating disorders such as depression and anxiety.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3,5-Dinitrobenzenesulfonyl chloride is a sulfonyl chloride that is used as a precursor in the synthesis of dendrimers. 3,5-Dinitrobenzene-1-sulfonyl chloride has been used to synthesize dendrimers with sulfonate groups on their surface. The sulfonate groups can be used to attach other molecules to the dendrimer and provide functionality. This compound can also be used to form tetranitrochloride by reacting it with sodium chlorite in aqueous solution.

<p>5-Chloro-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione is a dipole that has a geometry of an equilateral triangle with a dihedral angle of 120°. It has two hydrogen bonds and one intermolecular hydrogen bond. The molecule is photodimerized in low concentration and can form dimers by stacking interactions at low concentrations. This compound also interacts with uracils and has been shown to be stable when exposed to light. 5-Chloro-1,3-dimethylpyrimidine-2,4-dione has been shown to have interactions with the ftir spectra of other compounds.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Chloromethyl)pyrrolidin-2-one is a synthetic molecule that is used as an ion exchanger. It has been shown to be effective for the removal of chlorides, phosphates, and sulfates from solutions. This compound can also be used as a reagent in organic synthesis and can be used to prepare other compounds with higher molecular weights. 1-(Chloromethyl)pyrrolidin-2-one has been shown to interact with silicon and form a number of stable complexes. This molecule is labile and undergoes ring opening under acidic conditions to release chloride ions. X-ray diffraction studies have shown that 1-(chloromethyl)pyrrolidin-2-one adopts a planar conformation in the solid state.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methyl-1,10-phenanthroline (4MP) is a functional molecule that has been extensively studied for its use as an anticancer agent. 4MP is a racemic mixture of 4-methyl and 1,10-phenanthroline enantiomers. It has shown anticancer activity in the L1210 murine leukemia model and cisplatin-resistant human ovarian cancer cells. The binding constants of 4MP to DNA depend on the orientation of the molecule with respect to the DNA helix. The cis configuration binds more tightly than the trans configuration, which may be due to steric hindrance. 4MP inhibits luminescence by interacting with micelles and forming aggregates in water.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 5-amino-3-methyl-1-benzothiophene-2-carboxylate is a drug that inhibits the activity of 2,4-dichlorobenzoic acid, an enzyme involved in energy metabolism. It has been shown to bind to and inhibit a number of other enzymes, including carboxylase, decarboxylase, and transferase. This drug is used as an antimicrobial agent against pandemic influenza and other respiratory infections. The drug binds to the carboxylate group of the enzyme's active site and coordinates with the metal ion via its benzoate moiety. The coumarin derivative may be responsible for the observed inhibition by binding to a different site on the enzyme or by interacting with a second molecule of ethyl 5-amino-3-methyl-1-benzothiophene-2-carboxylate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Aminoquinoline-3-carboxylic acid is a heterocyclic compound that contains a carboxylic group and a cyano group. It is used in research as a trackable cation. 2-Aminoquinoline-3-carboxylic acid has been shown to inhibit the binding of chloride ions to the cytoplasmic membrane, which decreases the permeability of the membrane to chloride ions, thus inhibiting its transport into cells. This compound also inhibits nitric oxide synthase and exhibits anti-inflammatory effects by suppressing cytokine release from macrophages. 2-Aminoquinoline-3-carboxylic acid may be synthesized from 2 amino quinolines and chlorides.</p>

<p>5-Phenylpyrimidin-2-amine is a synthetic chemical that is an intermediate in the production of other chemicals. It can be used to produce sulfate, nucleophilic amines, or active methylene compounds. 5-Phenylpyrimidin-2-amine can also be used as a starting material for the production of triethyloxonium chloride and 13C NMR spectroscopy reagents. 5-Phenylpyrimidin-2-amine has a nucleophilic nature and is capable of reacting with a variety of functional groups. This chemical can undergo demethylation reactions with sulfate, chlorides, and cyanamide, which are all reactive with the methyl group on this chemical. 5-Phenylpyrimidin-2-amine is an isomeric compound that exists in two forms: one with substituents at positions 2 and 6 (syn) and one with substituents at positions 3</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Chroman-8-carboxylic acid is a phenolic compound that has biological activity. It is found in many plants, including crop plants like sugarcane and rice. Chroman-8-carboxylic acid can be isolated from the tannins of these plants, as well as from the bark of trees such as oak and chestnut. Chroman-8-carboxylic acid has been shown to have significant antibacterial activity against Gram positive bacteria such as Staphylococcus aureus. This compound also shows low activity against Gram negative bacteria such as Escherichia coli. The potential use for this compound is in fungal control because it is found in many types of fungi and has been shown to inhibit the growth of some species.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl carbamate is a diluent that can be used to reconstitute fatty acids at high concentrations. It is also used in pharmaceutical preparations and conjugates. It has been shown to have an antiviral effect against chlamydia and has been used as a pharmaceutical dosage for the diagnosis of radiation exposure. The diluent can also be used in pharmaceutical preparations and conjugates, but it is not active against viruses or bacteria.</p>

<p>4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzonitrile is a versatile research chemical with various applications. It contains fluorine and is commonly used in the synthesis of copolymers, phenolic acids, and hydrocarbons. This compound also finds application in the field of medicine, where it has been studied for its potential as an antioxidant and for its activity on dopamine receptors. Additionally, 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzonitrile has been found to exhibit surface energy properties and can be used in interfacial processes or as an electrolyte. Its wide range of characteristics makes it a valuable compound for researchers across different fields.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-3-carboxylic acid is a broad spectrum inhibitor of human herpesvirus 1 (HSV-1) and human herpesvirus 2 (HSV-2). It is a non-nucleoside inhibitor of DNA polymerases. The compound binds to the active site of the enzyme, preventing the formation of an active complex with the template strand. 2-Chloro-3-carboxylic acid inhibits both DNA polymerases and RNA polymerases. This antiviral drug has been shown to inhibit HSV replication in culture by 95%. 2C3CA has been shown to have high specificity for HSV type 1 and type 2, as well as for all other human DNA viruses, including adenoviruses and cytomegalovirus.<br>2C3CA is not active against other animal DNA viruses or bacterial DNA viruses.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-phenylpropanoate is the product of a lipase-catalyzed reaction between methanol and phenylacetic acid. The hydrolysis of the ester bond releases methanol, which can then react with another molecule of phenylacetic acid to form methyl 2-phenylpropanoate. Methyl 2-phenylpropanoate is a key intermediate in the synthesis of beta blockers, such as propranolol. It can also be used as an alternative to cyclopentane for synthesizing stereoisomers of cyclohexane. The reaction mechanism involves an activation energy that is kinetically favorable and has an asymmetric synthesis. The stereoselectivity of this reaction is due to the use of an acid catalyst and a chiral ligand.</p>

<p>Versatile small molecule scaffold</p>

<p>5,6-Dihydro-4H-pyran-2-carboxylic acid is a diluent that is used in the manufacture of dry powders. It is also used as a diluting agent for influenza vaccines. 5,6-Dihydro-4H-pyran-2-carboxylic acid is one of the most commonly used diluents for vaccines and other biological products. This compound has been approved by the FDA for use in both injectable and nasal flu vaccine preparations. The particle size of this compound ranges from microns to millimeters. 5,6-Dihydro-4H-pyran-2-carboxylic acid can be mixed with water or saline to produce a solution with a pH between 3 and 8.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Carboxymethyl)-1H-indole-2-carboxylic acid is an intramolecular cyclization reaction that involves the amination of a propanoic acid and a ring system. This reaction is analogous to the synthesis of 2,5-diaminopentane, which is also a cyclization of an amine to form a five-membered ring. The nmda receptor complex has been shown to be efficient in binding 3-(carboxymethyl)-1H-indole-2-carboxylic acid and other analogues of this compound. In addition, 3-(carboxymethyl)-1H-indole-2-carboxylic acid has shown affinity for the glycine site on the nmda receptor complex. The chemistry behind this drug is not well understood due to its complexity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methoxyethyl)aniline is a chemical compound with the chemical formula CH3OCH2NHCH2CH2SCl. It is a colorless, water-soluble liquid and has a pungent odor. 2-(2-Methoxyethyl)aniline reacts with trimethylamine to form trimethylammonium chloride. It also reacts with dimethyl sulfate to form dimethyl sulfate and methylamine. The reaction with hydrazine yields anilinohydrazide and methylated aniline, which can then be converted into borohydride or chlorotrimethylsilane by reacting it with lithium borohydride or chlorotrimethylsilane respectively.<br> 2-(2-Methoxyethyl)aniline is used in the synthesis of various organic compounds such as pharmaceuticals, dyes, pesticides, and perfumes.</p>

<p>Versatile small molecule scaffold</p>