Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(4-Bromophenyl)-2-propen-1-ol is a biomolecule that is a stereoisomer of epoxypropane. It can be synthesized by the epoxidation of 3-bromobenzaldehyde with sodium hydroxide and tetrahydrofuran in the presence of catalysts such as FeCl3. This compound has been shown to have affinity for rat brain tissue and to inhibit the reuptake of noradrenaline, which is a neurotransmitter. The stereogenic center, which is located at the C3 position, can be substituted with other groups such as alcohols or cinnamyl. The bromohydrins formed during this reaction are nucleophiles that can also react with electrophilic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Diiodobicyclo[1.1.1]pentane is a derivatized molecule that can be used in a number of different ways. It has been used to study the conformation and strain of this molecule, as well as its reactivity with other molecules. 1,3-Diiodobicyclo[1.1.1]pentane has been shown to have an increased susceptibility to nucleophilic attack by amines, which may be due to the presence of the sulfoxide group on the ring system. This mechanistic study provides insight into how this molecule can be functionalized for different purposes.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-Amino-4-ethoxythiophene-3-carbonitrile is a chemical compound that contains an orthoacetate group, which is an acetyl group in the 2 position and an ethoxy group in the 4 position. It is used in organic synthesis as a building block for introducing orthoalkoxysubstituents into ring systems. This compound can be prepared by transesterification of trimethylorthoacetate with 2-aminoethanethiol followed by reduction of the nitrile to amine with zinc dust and hydrochloric acid. The trimethylorthoacetate can be prepared by reacting methyltriphenylphosphonium bromide with trimethyl orthoformate and potassium hydroxide. This reaction has been shown to be efficient and high yielding.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Propan-2-yl 3,4-dihydroxybenzoate is a chemoattractant protein that is reactive with hydrogen bonds. It has been shown to have anti-inflammatory properties and may be effective in the treatment of inflammatory diseases. Propan-2-yl 3,4-dihydroxybenzoate has been shown to cause apoptosis in microglia cells in vitro. This compound also activates toll-like receptor 4 and increases expression of proinflammatory cytokines such as tumor necrosis factor α (TNFα) and interleukin 1β (IL1β). In addition, it has been found to inhibit the growth of cancer cells through an effect on the mitogen activated protein kinase pathway.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

4,5-Diaminopentanoic acid dihydrochloride is a semialdehyde that can be used in the synthesis of α-amino acids. It is also an intermediate in the synthesis of 4,5-diaminopentanoic acid, which is a precursor to polyamides. This compound has been shown to inhibit glutarate dehydrogenase and semialdehyde dehydrogenase.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

4,6-Dimethoxy-1H-indole-2-carboxylic acid is an aralkyl compound that belongs to the group of vitamin E compounds. It is a natural component of linoleic acid and indole-2-carboxylic acid. This compound is used as an antioxidant in the preparation process for animal feed and stearic acid. 4,6-Dimethoxy-1H-indole-2-carboxylic acid has been shown to inhibit growth and/or stearic acid condition in mice.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methoxy-1,2-dimethyl-1H-indole-3-carboxylic acid is a compound that has been shown to inhibit the polymerization of polymers. This chemical can be used as a sealant due to its ability to form a protective film on surfaces. It is also an effective polymerization inhibitor for polymers such as polyvinyl chloride and polystyrene, which are both used in the production of solar cells. 5-Methoxy-1,2-dimethyl-1H-indole-3-carboxylic acid can also be used to enhance the performance of solar cells by preventing water vapor from degrading the polymers that they are made of. The optimal wavelength range for this chemical is between 200 and 400 nm.</p>