Building Blocks
Subcategories of "Building Blocks"
- Boronic Acids & Boronic Acid Derivatives(5,780 products)
- Chiral Building Blocks(1,241 products)
- Hydrocarbon Building Blocks(6,100 products)
- Organic Building Blocks(61,024 products)
Found 205297 products of "Building Blocks"
(1-Methylpiperidin-4-yl)methanol
CAS:(1-Methylpiperidin-4-yl)methanol is a potent inhibitor of the kinases vegfr-2 and vesicular glutamate transporter 2 (vglut2). It is also active against human tumor xenografts. The inhibitory activity was determined to be due to its ability to bind and covalently modify tyrosine residues in the kinase domain. The inhibitory potency of (1-Methylpiperidin-4-yl)methanol was found to be constant, regardless of oxygenation status. This suggests that the inhibition is not due to the binding of oxygenated metabolites. In vitro experiments showed that it inhibits cellular proliferation by blocking protein synthesis and arresting cells at G1 phase. This drug has potential as an antitumor agent because it inhibits tumor growth without affecting normal tissue or causing significant toxicity in animal models.
Formula:C7H15NOPurity:Min. 95%Color and Shape:Colourless to yellow liquid.Molecular weight:129.2 g/molL-Pyroglutamyl-L-histidyl-L-prolinamide
CAS:L-Pyroglutamyl-L-histidyl-L-prolinamide (PGC) is a pyrrolidine that is used for the treatment of neurologic disorders. It has been shown to be effective in treating depression and a number of other neurologic disorders, including Parkinson's disease, Alzheimer's disease, and epilepsy. PGC has also been shown to have an antidepressant effect in women with depression who are pregnant or have recently given birth. In addition, it has been found to be clinically effective in the treatment of symptoms associated with Parkinson’s Disease. PGC is not absorbed into the bloodstream and must be injected directly into muscle tissue or fat cells in order to produce its therapeutic effects.Formula:C16H22N6O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:362.38 g/molL-5-Methyltetrahydrofolate calcium
CAS:L-5-Methyltetrahydrofolate calcium is also known as calcium levomefolate; N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, calcium salt; and L-5-MTHF. L-5-Methyltetrahydrofolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.Formula:C20H23CaN7O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:497.52 g/mol6-Methyluracil
CAS:6-Methyluracil is an antimetabolite that inhibits protein synthesis and is therefore used in the treatment of infectious diseases. 6-Methyluracil has two hydroxyl groups, which are located in adjacent positions on the ring. The optimum concentration for this drug is 3-10 μM, which can be achieved with a malonic acid buffer solution at pH 7.4. 6-Methyluracil reacts with sodium succinate to form an acid complex, which may have antiinflammatory activity. 6-Methyluracil has been shown to inhibit prostaglandin synthesis and exhibits a reaction with radiation to produce photoproducts that can be detected by analytical chemistry.Formula:C5H6N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:126.12 g/mol6-Mercaptopurine hydrate
CAS:6-Mercaptopurine is a purine analog that suppresses the production of white blood cells by inhibiting the enzyme thiopurine methyltransferase. It has been used to treat bowel disease and also for long-term suppression of the immune system in patients with autoimmune diseases. 6-Mercaptopurine is metabolized to 6-mercaptopurine, which is then converted to dinucleotide phosphate (dNTP) by group P2 enzymes. This conversion allows 6-mercaptopurine to inhibit dNTP synthesis and cell division. The effects of 6-mercaptopurine are potentiated when given in conjunction with azathioprine, another drug that inhibits purine metabolism. 6-Mercaptopurine is not active against human serum albumin or erythrocytes because it cannot be cleaved into an active form by these proteins. However, it does inhibit enzyme activities such as DNA polymerase, RNA polymerase, and proteinFormula:C5H4N4S•H2OPurity:Min. 97 Area-%Color and Shape:Yellow PowderMolecular weight:152.18 g/mol6-Methoxyindole-2-carboxylic acid methyl ester
CAS:6-Methoxyindole-2-carboxylic acid methyl ester is a pyrroloquinoline alkaloid with cytotoxic and antiproliferative activities. It inhibits the growth of cancer cells in culture by inducing apoptosis and cell cycle arrest. 6-Methoxyindole-2-carboxylic acid methyl ester has been shown to be effective against breast cancer cell lines in vitro and to inhibit the proliferation of breast cancer cells in vivo. This compound also inhibits the growth of a number of other cancer cell lines such as prostate, colon, lung, liver, stomach, and leukemia. The mechanism of action for this compound is thought to be due to its ability to act as an intramolecular quencher of reactive oxygen species (ROS) or as an inhibitor of DNA synthesis through inhibition of ribonucleotide reductase activity.
Formula:C11H11NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:205.21 g/mol6-Methoxyindole-2-carboxylic acid
CAS:6-Methoxyindole-2-carboxylic acid (6MI) is a potent inhibitor of the enzyme catechol-O-methyltransferase (COMT). This inhibition prevents the conversion of catecholamines, such as dopamine and norepinephrine, to their corresponding methylated products. COMT inhibitors are used clinically to treat Parkinson's disease and other diseases that result from excessive levels of these neurotransmitters. 6MI is also an effective inhibitor of tyrosinase activity in vitro. It has been shown to inhibit the synthesis of melanin by melanocytes and inhibits the production of eumelanin, which is responsible for black or brown skin pigments. The inhibitory potency of 6MI was found to be greater than that for kojic acid, arbutin, and hydroquinone. Optimization studies showed that 6MI was most potent at a concentration of 1 mM and had an IC50 value of 0.3 mM in
Formula:C10H9NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:191.18 g/mol3-(4-Fluorophenyl)cyclopentan-1-amine
CAS:Versatile small molecule scaffoldFormula:C11H14FNPurity:(%) Min. 80%Molecular weight:179.23 g/mol4-Mercaptoethylpyridine HCl
CAS:Used for antibody separation by hydrophobic charge induction chromatography
Formula:C7H9NS·HClPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:175.68 g/mol6-Methoxyindole
CAS:6-Methoxyindole is an acetate extract of the plant 5-methoxyindole. It has been shown to be a 5-HT1A receptor agonist in animals, and has been shown to have cardiac effects in rats. 6-Methoxyindole is also used as a precursor for the synthesis of diphenylacetylindoles. 6-Methoxyindole is one of the molecules that can be recombined to form a batcho-leimgruber indole (BLI).
Formula:C9H9NOPurity:Min. 99 Area-%Color and Shape:PowderMolecular weight:147.17 g/molMaleimide
CAS:Maleimide is a chemical compound that can be synthesized from maleic anhydride and hydrogen fluoride. It has been used as a fluorescent probe for the measurement of electrochemical impedance spectroscopy (EIS) in biological systems. Maleimide is also used to study the interaction with mouse monoclonal antibody, which can be used to detect the presence of specific proteins or antigens in blood. Maleimides are covalently linked to proteins and other macromolecules through their thiol groups, forming a stable linkage. Maleimide reacts with hydrogen gas at high temperatures, leading to a decrease in its redox potentials. The reaction solution can be analyzed by plasma mass spectrometry, which determines the concentration of maleimide and its reactants by measuring ions produced by ionization or fragmentation reactions.Formula:C4H3NO2Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:97.07 g/mol6-Methoxy-2-naphthol
CAS:6-Methoxy-2-naphthol is a synthetic compound. It has been shown to be an effective antibacterial agent against Gram-positive bacteria when tested in vitro. 6-Methoxy-2-naphthol also inhibits methyltransferase activity and can be used in the treatment of cancer. The optical properties of 6-Methoxy-2-naphthol have been studied extensively, and it has been found to have strong absorption bands at 350 nm and 575 nm, making it a potential candidate for photodynamic therapy.Formula:C11H10O2Purity:Min. 95%Color and Shape:Brown PowderMolecular weight:174.2 g/mol1H-Pyrrolo[2,3-c]pyridin-7-amine
CAS:Versatile small molecule scaffoldFormula:C7H7N3Purity:Min. 95%Color and Shape:PowderMolecular weight:133.15 g/molN1-(4,5-Dihydro-1H-imidazol-2-yl)benzene-1,4-diamine dihydrochloride
CAS:Versatile small molecule scaffoldFormula:C9H14Cl2N4Purity:Min. 95%Color and Shape:PowderMolecular weight:249.14 g/molMethyl 2-hydroxybutanoate
CAS:Versatile small molecule scaffoldFormula:C5H10O3Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:118.13 g/mol2-Methoxybenzene sulphonamide
CAS:2-Methoxybenzene sulphonamide is an anti-cancer drug that belongs to the class of hydroxylated aromatic compounds. It has been shown to inhibit the growth of cancer cells in culture and in animals, and to prevent the formation of metastases. 2-Methoxybenzene sulphonamide is also a vasodilator drug used for the treatment of congestive heart failure. This drug binds to dopamine receptors in humans and may inhibit phosphatase activity. It has been shown to act as an antihypertensive by inhibiting angiotensin II mediated hypertrophy of cardiac tissue.Formula:C7H9NO3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:187.22 g/mol4-Methoxyindole
CAS:4-Methoxyindole is a high-performance liquid chromatography (HPLC) solute that has been shown to interact with the fluoroquinolone antibiotic, 4-methoxyindole. The interaction of the two substances may be due to the formation of condensation products. 4-Methoxyindole can also react with monoamine oxidase inhibitors and form fluorescence as a result of chemical reactions. This compound is used in HPLC as a stationary phase for the separation of solutes by column chromatography. The density and bond cleavage properties of this substance make it suitable for use in this application.Formula:C9H9NOColor and Shape:PowderMolecular weight:147.17 g/molPivaldehyde
CAS:Intermediate in organic syntheses; stereoselective synthesisFormula:C5H10OPurity:Min. 95%Color and Shape:Colorless Clear LiquidMolecular weight:86.13 g/mol2-(4-Methylphenyl)piperidine
CAS:Versatile small molecule scaffold
Formula:C12H17NPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:175.27 g/molN-(3-Aminopropyl)-N-dodecylpropane-1,3-diamine
CAS:N-(3-Aminopropyl)-n-dodecylpropane-1,3-diamine, also called N,N-bis(3-aminopropyl)dodecylamine and laurylamine dipropylenediamine, is dodecylamine substituted with 2 propylamine units. Laurylamine dipropylenediamine is a non-ionic surfactant, antimicrobial agent, preservative, emulsifying agent, dispersing agent, corrosion inhibitor and an anti-static agent used in hair products.Formula:C18H41N3Purity:(¹H-Nmr) Min. 85 Area-%Color and Shape:Colorless Clear LiquidMolecular weight:299.54 g/mol
