Amines

<p>Applications 3-Amino-3-(3-(p-tolyloxy)phenyl)propanoic Acid is a useful chemical reagent.<br></p>

<p>Applications Methyl 2-Aminothioazole-4-carboxylate (cas# 118452-04-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications 2-(methylamino)octanoic acid (cas# 101080-67-5) is a useful research chemical.<br></p>

<p>Applications 2-(3-Aminopropylamino)ethanol is the hydroxy analogue of WR-1065 (A576820), a metabolite of Amifostine (A576810). Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2-(3-Aminopropylamino)ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Antonadou, D., et al.: Int. J. Rad. Oncol. Biol. Phys., 52, 739 (2002); Kemp, G., et al.: J. Clin. Oncol., 14, 2101 (1996)<br></p>

<p>Applications 4-Aminophenethyl Alcohol, is a building block that can be used in the synthesis of various compounds, such as in synthesis of 4-aminostyrene, and in functionalization of graphene nanoplatelets.<br>References Li L, et al.Polymer Journal 33(4), 364-370; Hagiwara T, et al. Macromolecules 24(26), 6856-6858, (1991);<br></p>

<p>Applications A reactant used in the preparation of (-)-Amathaspiramide F.<br>References Sakaguchi, K. et al.: Tetrahedron, 65, 10355 (2009); Sakaguchi, K. et al.: Org. Lett., 10, 5449 (2008)<br></p>

<p>Applications 6-Aminohexanenitrile (cas# 2432-74-8) is a compound useful in organic synthesis.<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine (N490150), a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine (F232370), a calcium entry blocker that has antihypertensive properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. &amp; Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980)<br></p>

<p>Applications [2-(aminocarbonyl)phenoxy]acetic acid (cas# 25395-22-6) is a useful research chemical.<br></p>

<p>Applications Ammonium Bromide is used as a bromide activated chloramine biocide for effective control of volatile fatty acids and catalase and biofilm elimination in paper making industry. Also applied in biopharmaceuticals and dosage form designs.<br>References Bharati, S., et al.: Appita J., 56, 426 92003); Torosian, G., et al.: Am. J. Hosp. Pharm., 30, 716 (1973)<br></p>

<p>Applications trans-4-(Dimethylamino)-3-buten-2-one is an reagent used in the synthetic preparation of various substances.<br>References Maggiulli, C.A., et al.: Org. Prep. Pro. Int., 16, 31 (1984); Afarinkia, K., et al.: Sci. Syn., 14, 275 (2003);<br></p>

<p>Applications Ammonium 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonate (CAS# 29081-56-9) is a fluorosurfactant used as an additive to increase heat stability and resistance of materials.<br>References Gloeckner, V.; et al.: Tenside, Surfactants, Detergents, 26, 376 (1989).<br></p>

<p>Applications 2-Amino-N,N-dimethylbenzenesulfonamide is an intermediate used to prepare LDK378 as potent and selective anaplastic lymphoma kinase inhibitor.<br>References Marsilje, T., et al.: J. Med. Chem., 56, 5675 (2013)<br></p>

<p>Applications Azido-PEG1-amine (cas# 464190-91-8) is a useful research chemical.<br></p>

<p>Applications N-Benzoylcarbonylaminoacetamidine Hydrochloride (cas# 50850-19-6) is a compound useful in organic synthesis.<br>References Kitagawa, H., et al.: Bioorg. Med. Chem. Lett., 17, 4982 (2007),<br></p>

<p>Applications 1-(9H-Purin-6-ylamino)propan-2-ol is a reagent used for organic synthesis and also functions as a plant growth regulator.<br>References Gao, Y., et al.: J. Heterocyclic Chem., 53, 579 (2016); Oda, A., et al.: From Faming Zhuanli Shenqing (2016), CN 105503875 A 20160420; Lira, E. P.: J. Org. Chem., 33, 3355 (1968)<br></p>

<p>Applications 4-amino-N-(2,6-dimethylphenyl)benzamide (cas# 787-93-9) is a useful research chemical.<br></p>

<p>Applications N1,N1,N2,N2-Tetrakis(2-aminoethyl)-1,2-ethanediamine is used in the preparation of strong circularly polarized luminescence of rare earth complexes<br>References Petoud, S. et al.: J. Am. Chem. Soc., 129, 77 (2007); Xu, J., et al.: J. Am. Chem. Soc., 133, 19900 (2011);<br></p>

<p>Applications Amino-peg1-t-butyl Ester is a reagent used in the preparation of β2 adrenergic receptor agonists and muscarinic receptor activity antagonists.<br>References Donald, D. K., et al.: PCT Int. Appl., WO 2011048409 A1 WO2010-GB51751 (2011)<br></p>

<p>Applications A caged, photolabile Nitric Oxide donor that is useful for delivering nitric oxide into intracellular compartments in microsecond time scale without any cytotoxic effects.<br>References Namiki, S., et al.: Bioorg. Med. Chem., 7, 1695 (1999),<br></p>

<p>Applications tert-Butyl 2-Aminobenzoate is a useful reagent for preparing alkylamino quinazolinones.<br>References Lu, C., et al.: J. Org. Chem., 83, 1154 (2018)<br></p>

<p>Applications 3-DI-N-PROPYLAMINO-1-PROPYNE (cas# 6323-79-1) is a useful research chemical.<br></p>

<p>Applications (2S,2aR,2aS,8aR)-2a-(2-((Cyclopropylmethyl)(methyl)amino)ethyl)-2,4,8a-trihydroxy-2,2a,8a-tetrahydro-1H-indeno[1,7,6-bcd]benzo-2-carboxylic Acid is an intermediate used in the synthesis of (4R,4aS,6S,6aR,11bS)-6-Carboxy-3-(cyclopropylmethyl)-1,2,3,4,4a,5,6,6a-octahydro-4a,6,8-trihydroxy-3-methyl-4,11-methanobenzofuro[3',2':2,3]cyclopenta[1,2-c]pyridinium, Inner Salt (C176953), which is an impurity/degradation of N-methyl Naltrexone (M320350), a metabolite of Naltrexone (N285750).<br>References Wall, M., et al.: Drug Metab. Dispos., 12, 677 (1984), Jones, D., et al.: .: Bioorg. Med. Chem., 13, 6727 ( 2005), Chen, T., et al.: Drugs Future, 32, 771 (2007); Chem. and Eng. News p.4 Jan. 23, (2017)<br></p>

<p>Applications 2-Amino-2-cyclopropylpropanenitrile, is an enamine building block that can be used in the synthesis of various chemical compounds, such as in synthesis of 5-substituted hydantoins, and Ketone-Derived Enamides.<br>References Murray, R. G. et al.: Organic &amp; Biomolecular Chemistry, Vol: 6, P: 988-99 1 (2008); Coussanes, G. et al.: euro. J. Org. Chem, Vol 2016, P: 4176-4188 (2016);<br></p>

<p>Applications 2,2-Diethoxy-N-ethylethanamine is used in the preparation of 1-substituted-2-mercaptoimidazoles with antithyroid activity.<br>References Jones, R.G.J. Am. Chem. Soc., 71, 4000 (1949)<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Applications (1R)-2,3-Dihydro-N-2-propen-1-yl-1H-inden-1-amine Ethanedioate is an intermediate used in the synthesis of propargylated aminoindan derivatives via allylation, bromination, dehalogenation sequence.<br>References Phull, M., et al.: PCT Int. Appl., WO 2009081148 A1 20090702 (2009)<br></p>

<p>Applications Used for the preparation of dihydrouracils as anti-ictogenic or anti-epileptogenic agents.<br>References Akoulitchev, S., et al.: Nature, 377, 557 (1995), Marshall, N., et al.: J. Biol. Chem., 270, 12335 (1995), Marshall, N., et al.: J. Biol. Chem., 271, 27176 (1996), Shapiro, G., et al.: J. Clin. Oncol., 24, 1770 (2006),<br></p>

<p>Applications 3-Aminocyclohexanol_x000D_(cis/trans mixture) (cas# 6850-39-1) is a compound useful in organic synthesis.<br></p>

<p>Applications N-aminomorpholine-4-carbothioamide (cas# 6499-15-6) is a useful research chemical.<br></p>

<p>Applications 1-Decylamine is an intermediate forming the phosphatidylcholine-decylamine liposomal membranes.<br>References Kotynska, J., et al.: J. Bioenerget. Biomembrane., 40, 637 (2008);<br></p>

<p>Applications 5-Aminopentanenitrile Hydrochloride is a useful research chemical.<br></p>

<p>Applications 9-(2-(Benzyloxy)ethyl)-2-((2-(benzyloxy)ethyl)amino)-1H-purin-6-(9H)-one is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>

<p>Applications N,N-Dimethyl-p-phenylenediamine (DMPD) has been used to n-dope bilayer graphene (BG) along with p-dope of tetracyanoethylene bilayer graphene to increase the band gap of DMPD/BG. N,N-Dimethyl-p-phenylenediamine (DMPD) has been shown to inhibit corrosion of mild steel in a sulphuric acid medium.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, T.H., et. al.: J. Phys. Chem. C., 117, 12873 (2013); Singh, K.U., Dubey, R.S.: Int. J. Chem., 1, 366 (2012)<br></p>

<p>Applications 4-(3-aminopropyl)-N,N-dimethylaniline (cas# 112103-97-6) is a useful research chemical.<br></p>

<p>Applications 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid is used for preparation of glutamic acid-containing acylating reagents for selective acylation of amino group(s) in peptides or proteins.<br>References Christensen, C., et al.: PCT Int. Appl. (2010), WO 2010084169 A2 20100729.<br></p>

<p>Applications 3-Amino-1,2-propandiol is used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Neugebauer, G. &amp; Neubert, P.: Eur. J. Drug. Metabol. Ph., 16, 257 (1991); Neugebauer, G. et al.: J. Cardiovasc. Pharm., 10, S85 (1987)<br></p>

<p>Stability Temperature Sensitive<br>Applications A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.<br></p>

<p>Applications tert-Butyl (2-((4-Aminophenyl)amino)-2-oxoethyl)carbamate is an intermediate in the synthesis of (E)-2-Formamido-N-(4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)acetamide (F792100), a compound useful in organic synthesis.<br></p>

<p>Applications (S)-(+)-Z-4-Amino-2-hydroxybutyric Acid is used in the synthesis of aminoglycoside antibiotics.<br>References Rai, R. et al.: Org. Lett., 8, 887 (2006); Li, Jie. et al.: J. org. Chem., 72, 4055 (2007);<br></p>

<p>Applications 2-Aminomethyl-1,4-benzodioxane is used in the synthesis of N-substituted (dihydrobenzodioxinyl)methylamine derivatives as D2 antagonists/5-HT1A partial agonists with potential as atypical antipsychotic agents in relation to affinity for α1 adrenoceptors.<br>References Birch, A. M., et al.: J. Med. Chem., 42, 3342 (1999);<br></p>

<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>

<p>Applications N-Carbobenzoxy-1,4-diaminobutane HCl is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia.<br>References Teranishi, H.; et al.: PCT Int. Appl. 215 pp. Patent 2004 CODEN:PIXXD2<br></p>

<p>Applications 2-[2-(2-azidoethoxy)ethoxy]ethanamine (cas# 166388-57-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Amino-2-chloroquinazolin-4(1H)-one is a synthetic reagent.<br></p>

<p>Applications 1,4-Phenylenediamine-13N2 is the isotope labelled analogue of 1,4-Phenylenediamine (P319845), an organic compound that is a derivative of aniline and a main ingredient for the production of polymers and hair dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, K., et al.: J. Med., 13, 131 (1982), Baud, F., et al.: J. Toxicol. Med., 4, 279 (1984), Ashraf, W., et al.: Human Exp. Toxicol., 13, 167 (1994),<br></p>

<p>Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.<br></p>

<p>Applications Tris(N,N-dimethylaminopropyl)amine has been used in the synthesis of nickel(II) and cobalt(II) complexes with the propylene-bridged tripod ligand tris(3-dimethylaminopropyl)amine (donor set N4).<br>References Morassi, R., Dei, A.: J. Chem. Soc., 12, 2024 (1971)<br></p>

<p>Stability Volatile<br>Applications 2-Furfurylamine is used in the synthesis of 2-Amino-N-(2-furylmethyl)propanamide, as a novel alanylglycine equivalent synthesized by bacilysin synthetase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mah, R., et al.: Appl. Microbiol., 15, 866 (1967), Faber, K., et al.: Pure Appl. Chem., 69, 1613 (1997), Marahiel, M., et al.: Chem. Biol. 4, 561 (1997),<br></p>

<p>Applications 2-Dimethylaminoethyl Benzilate is an intermediate in the synthesis of Propinox (P771500), an antispasmodic agent used in the treatment of moderate to severe colic pain of biliary origin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mishra, R., et al.: Pharma. Chemica., 2, 185 (2010);<br></p>

<p>Applications Methyl 4-aminosalicylate<br></p>

<p>Applications N-Hydroxybenzylamine Hydrochloride, is a versatile intermediate for the synthesis of various pharmaceutical compounds. It is used for the preparation of Ticagrelor (T437700) derivatives as novel antiplatelet agents.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007);<br></p>

<p>Applications 4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(3-(Dimethylamino)propyl)dodecanamide is used in the study of surface chemistry and colloids as a new surfactnt for hydrate anti-agglomeration in hydrocarbon flowlines and seabed oil capture.<br>References Sun, Minwei, Journal of Colloid and Interface Science, 402, 312-319, (2013)<br></p>