Amines

<p>Applications Tetrabutylammonium Hydroxide is used in biological studies for the detection of counter-anion effect on antimicrobial activity of tetrabutylammonium salts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ingalsbe, M.L., et al.: Bioorg. Med. Chem., 19, 4984 (2009)<br></p>

<p>Applications (S)-3-Aminobutan-1-ol can be used as an intermediate in the preparation of compounds having HIV integrase inhibitory activity.<br>References Johns, B. et al.: J. Med. Chem., 56, 5901 (2013);<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Applications 6-Bromohexyltriethylammonium Bromide (cas# 161097-76-3) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications N-Benzyl-bis(2-chloroethyl)amine hydrochloride (cas# 10429-82-0) is a useful research chemical.<br></p>

<p>Applications (S)-tert-butyl 4-aminoazepane-1-carboxylate (cas# 878630-84-3) is a useful research chemical.<br></p>

<p>Applications Tetrabutylammonium Dibromochloride (cas# 64531-21-1) is a useful research chemical.<br></p>

<p>Applications 2,5-Bis(aminomethyl)tetrahydrofuran<br></p>

<p>Applications 5-Chloropyridazin-3-amine is an intermediate used to prepare aminopyrazines as novel, potent Nav1.7 antagonists.<br>References Bregman, H., et al.: Bioorg. Med. Chem. Lett., 22, 2033 (2012)<br></p>

<p>Applications Methyl 4-(Methylamino)picolinate is a pyridinyl building block and a useful synthetic intermediate.<br></p>

<p>Stability Hygroscopic<br>Applications 2-(2,5-diaminophenyl)ethanol Sulfate (cas# 93841-25-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Amino-6-oxo-4,5,6,7-tetrahydrobenzothiazole, is an intermediate in the synthesis of pharmaceutical and biologically active compounds including therapeutic agents. It is an intermediate for the synthesis of Pramipexole (P700755).<br>References Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)<br></p>

<p>Applications 4-(Methylamino)benzoic Acid (cas# 10541-83-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 4'-Dimethylaminophenyl acetylene<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications Lonidamine<br></p>

<p>Applications Tetrabutylammonium Diphenylphosphinate is used as a reagent in the synthesis of the potent antiviral agent (-)-Macrolactin A and its related compounds, (+)-Macrolactin E and (-)-Macrolactinic Acid, via a Stille cross-coupling reaction.<br>References Smith, A.B., et al.: J. Am. Chem. Soc., 120, 3935 (1998)<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications 2-cyclohexylpropan-1-amine (cas# 103254-49-5) is a useful research chemical.<br></p>

<p>Applications Tetramethylammonium Hydroxide is used to prepare a new family of silicate/aluminosilicate mesoporous molecular sieves.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beck, J., et al.: J. Am. Chem. Soc., 114, 10834 (1992).<br></p>

<p>Applications Used in the preparation of (R)-Sulforaphane (S699105).<br></p>

<p>Stability Light Sensitive<br>Applications A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aslan, K., et al.: J. Fluoresc., 14, 391 (2004), Gole, A., et al.: Langmuir, 20, 7117 (2004), Cavalcante, A., et al.: Biochem. Eng. J., 29, 258 (2006),<br></p>

<p>Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.<br></p>

<p>Applications DL-3-aminoisobutyric acid hydrate is a useful research chemical for organic synthesis and other chemical processes.<br>References Saito, N., et al.: Bunseki Kagaku, 63, 909 (2014)<br></p>

<p>Applications 4-Amino-1,3-benzenedisulfonic Acid is used as a reagent in the synthesis of arylazopyridoxal phosphate and phosphonate derivatives as P2 receptor antagonists.<br>References Kim, Y., et al.: Drug Develop. Res., 45, 52 (1998)<br></p>

<p>Applications tert-Butyl (3-(2-(2-(3-Aminopropoxy)ethoxy)ethoxy)propyl)carbamate is used as a reactant in the synthesis of gallium-labeled PET imaging agents for CXCR4 for potential cancer diagnosis.<br>References Poty, Sophie, et al.: Bioconjugate Chem., 27(3), 752-761 (2016)<br></p>

<p>Applications 5-(Aminomethyl)furan-2-carboxylic Acid Hydrochloride is a useful reagent in the preparation of novel heteroaromatic substrates of GABA aminotransferase.<br>References Hawker, D. D., et al.: Bioorg. Med. Chem., 20, 5763 (2012)<br></p>

<p>Applications Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutylpiperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy.<br>References Chezal, J.M., et al.: J. Medn. Chem., 51, 3133 (2008); Heinrich, T., et al.: J. Medn. Chem., 47, 4684 (2004);<br></p>

<p>Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Aminomethylbenzoic acid<br></p>

<p>Applications 3-Amino-3-(3-(p-tolyloxy)phenyl)propanoic Acid is a useful chemical reagent.<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications Tetramethylammonium Chloride is used as a reagent in the synthesis of β-Triglycidyl Isocyanurate (T793805); a crosslinker and neoplasm inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vargha, V., et al.: J. Therm. Anal. Calorim., 83, 199 (2006); Spreafico, F., et al.: Cancer Chemoth. Pharm., 5, 103 (1980)<br></p>

<p>Applications S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are often used as ligands in homogeneous catalysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Landau, O. et al.: Cancer Lett., 69, 203 (1993); Gant, T.G. et al.: Tetrahedron, 50, 2297 (1994);<br></p>

<p>Applications S-(3-((4-Aminophenyl)amino)-3-oxopropyl) Methanesulfonothioate is an intermediate used in the synthesis of (E)-S-(3-((4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)amino)-3-oxopropyl) methanesulfonothioate (H895230), which a useful research chemical.<br></p>

<p>Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ammonium Bromide is used as a bromide activated chloramine biocide for effective control of volatile fatty acids and catalase and biofilm elimination in paper making industry. Also applied in biopharmaceuticals and dosage form designs.<br>References Bharati, S., et al.: Appita J., 56, 426 92003); Torosian, G., et al.: Am. J. Hosp. Pharm., 30, 716 (1973)<br></p>

<p>Applications 2,4,6-Trimethyl-1,3-benzenediamine is a compound used in the synthesis of various polymers.<br>References Fritsch, D., et al.: Macromolec. Chem. Phys., 197, 701 (1996)<br></p>

<p>Applications 2-Amino-N,N-dimethylbenzenesulfonamide is an intermediate used to prepare LDK378 as potent and selective anaplastic lymphoma kinase inhibitor.<br>References Marsilje, T., et al.: J. Med. Chem., 56, 5675 (2013)<br></p>

<p>Applications tert-Butyl 2-(3-Aminophenyl)acetate can be used as anti-heparanase to treat diseases and disorders associated with heparanase activity.<br>References Giannini, G., et.al.: PCT Int. Appl., 103, (2018);<br></p>

<p>Applications 6-(4-Phenylbutoxy)-1-hexanamine is an intermediate in the synthesis of salmeterol (S090100), a structural analog of Albuterol (A514500).<br>References Goswami, J., et al.: Tetrahedron. Asym., 12, 3343 (2002);<br></p>

<p>Stability Hygroscopic<br>Applications Cyclobutylmethylamine Hydrochloride<br></p>

<p>Stability Hygroscopic<br>Applications Bis(3-chloropropyl)amine Hydrochloride is used in silica studies, and is grafted onto a silica support to evaluate CO2 adsorption.<br>References Yoo, C. et al.: Ind. Eng. Chem. Res., 59, 7061 (2020);<br></p>

<p>Applications (1S,2S)-1,2-Diphenyl-1,2-ethanediamine (cas# 29841-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyldibutylamine is a useful reagent for organic synthesis.<br></p>

<p>Applications 2-(Phenylamino)nicotinic Acid (cas# 16344-24-4) is a useful research chemical.<br></p>

<p>Applications 4-amino-3-hydroxybenzenesulfonamide (cas# 3588-76-9) is a useful research chemical.<br></p>

<p>Applications N4-Aminocytidine (cas# 57294-74-3) is a useful research chemical.<br></p>

<p>Applications 2-((tert-bButoxycarbonyl)amino)-2-(hydroxymethyl)-4-(4-octylphenyl)butyl Acetate is the intermediate in the synthesis of Mono-O-acetyl Fingolimod TFA (F524600), which is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001). Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002). Mtaloubian, M., et al.: Nature, 427, 355 (2004)<br></p>

<p>Applications An intermediate of Synergistin. Antibacterial.<br></p>

<p>Applications 4-(3-aminopropyl)-N,N-dimethylaniline (cas# 112103-97-6) is a useful research chemical.<br></p>

<p>Applications (benzyloxy)(methyl)amine (cas# 22513-22-0) is a useful research chemical.<br></p>

<p>Applications 5-chloro-2,1,3-benzoxadiazol-4-amine (cas# 80277-04-9) is a useful research chemical.<br></p>

<p>Applications (S)-(+)-Z-4-Amino-2-hydroxybutyric Acid is used in the synthesis of aminoglycoside antibiotics.<br>References Rai, R. et al.: Org. Lett., 8, 887 (2006); Li, Jie. et al.: J. org. Chem., 72, 4055 (2007);<br></p>

<p>Applications DL-2-Amino-1-pentanol is a useful intermediate for organic synthesis. It is used in the preparation of amino-substituted pyrimidine derivatives and other aminoethanethiol derivatives with potential antiradiation properties.<br>References Yoo, K. H., et al.: Korean J. Med. Chem., 9, 83 (1999); Fernandez, S., et al.: Synthesis, 9, 713 (1991)<br></p>

<p>Applications cyclopent-2-en-1-amine hydrochloride (cas# 91469-54-4) is a useful research chemical.<br></p>

<p>Applications ethyl (4-aminophenyl)carbamate (cas# 57399-97-0) is a useful research chemical.<br></p>

<p>Applications Cyclopentylmethanamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-Carbobenzoxy-1,4-diaminobutane HCl is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia.<br>References Teranishi, H.; et al.: PCT Int. Appl. 215 pp. Patent 2004 CODEN:PIXXD2<br></p>

<p>Applications Tetramethylammonium Tetrafluoroborate (cas# 661-36-9) is a useful research chemical.<br></p>

<p>Applications 2-(Tributylstannyl)-2-propen-1-amine (cas# 155258-22-3) is a compound useful in organic synthesis.<br></p>