Amines

<p>Applications (2R)-2-(dimethylamino)propan-1-ol (cas# 55197-05-2) is a useful research chemical.<br></p>

<p>Applications Used in the antileishmanial activity of lipidic amino alcohols.<br>References Coimbra, E.: Chem. Biol. Drug Des. 75, 233 (2010).<br></p>

<p>Applications 1-Decylamine is an intermediate forming the phosphatidylcholine-decylamine liposomal membranes.<br>References Kotynska, J., et al.: J. Bioenerget. Biomembrane., 40, 637 (2008);<br></p>

<p>Applications 9-(2-(Benzyloxy)ethyl)-2-((2-(benzyloxy)ethyl)amino)-1H-purin-6-(9H)-one is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>

<p>Applications 3-AZIDOPROPAN-1-AMINE (cas# 88192-19-2) is a useful research chemical.<br></p>

<p>Applications 6-Amino-1,3-dimethyl-5-nitrosouracil (cas# 3346-61-0) is a compound useful in organic synthesis.<br>References Varma, R., et al.: J. Ocular Pharmacol. Ther., 16, 571 (2000),<br></p>

<p>Applications Ethyl (1S,3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxycyclohexane-1-carboxylate, is a building block used in various chemicla synthesis. It can be used for the preparation of six stereoisomers of diaminocyclohexane carboxamide as key intermediates for synthesis of factor Xa inhibitors.<br>References Wang, X. et al.: Tetrahedron, Vol.73, Iss.11, P1381-1388 (2017);<br></p>

<p>Applications Tetrabutylammonium Hydroxide is used in biological studies for the detection of counter-anion effect on antimicrobial activity of tetrabutylammonium salts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ingalsbe, M.L., et al.: Bioorg. Med. Chem., 19, 4984 (2009)<br></p>

<p>Applications 3-(3-Butyn-1-yl)-3H-diazirine-3-ethanamine can be used as reactant/reagent in minimalist cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling.<br>References Li, Z., et al.: J Am Chem Soc, 136, 9990 (2014)<br></p>

<p>Applications 5-Amino-1,2,3-thiadiazole, as a thiadiazole derivative, is a privileged structure in medicinal chemistry and has been investigated for anticonvulsant and antimicrobial activities.<br>References Matsumoto, T., et al.: Masakuni; PCT Int. Appl. (2006), WO 2006054652 A1 20060526; Gommaa, A., et al.: Alexandria J. Pharm. Sci., 5, 153 (1991)<br></p>

<p>Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.<br>References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);<br></p>

<p>Applications 2,2-DIMETHOXY-1-PROPANAMINE (cas# 131713-50-3) is a useful research chemical.<br></p>

<p>Applications 1,4-Cyclohexanediamine<br></p>

<p>Applications tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate has been used as a reactant in the preparation of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 with potential use in osteoarthritis therapy.<br>References Durham, T.B., et. al.: J. Med. Chem., 57, 10476 (2014)<br></p>

<p>Applications [4-(Cyclopropylmethyl)phenyl]methanamine Hydrochloride is a useful research chemical for organic synthesis.<br></p>

<p>Applications 3-(methylamino)butan-1-ol (cas# 2704-55-4) is a useful research chemical.<br></p>

<p>Applications 5,6-Diaminouracil sulfate is an intermediate in the synthesis of Paraxanthine (P192500) and Paraxanthine analogs.<br>References Mueller, C.E., et al.: J. Med. Chem., 36, 3341 (1993),<br></p>

<p>Applications (S)-tert-butyl 4-aminoazepane-1-carboxylate (cas# 878630-84-3) is a useful research chemical.<br></p>

<p>Applications Clavulanic Acid 2-Amino-2,4,4-trimethylpentane Salt is an intermediate in the synthesis of Clavulanic Acid Potassium Salt (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reading, C. and Cole, M.: Antimicrob. Ag. Chemother., 11, 852 (1977); Ball, A.P., et al.: Lancet, 1, 620 (1980); Brogden, R.N., et al. Drugs, 22, 337 (1981)<br></p>

<p>Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.<br>References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides &amp; Nucleotides, 2, 21 (1983)<br></p>

<p>Applications methyl amino(2-bromophenyl)acetate hydrochloride (cas# 1219408-44-2) is a useful research chemical.<br></p>

<p>Applications 5-Aminononane-5-carboxylic Acid is a reagent used in the synthesis of Fmoc-α-​dialkylamino acids.<br>References Suresh B. et al.: Indian J. Chem. Section B: Chem. Inc. Med., 40B, 70 (2001);<br></p>

<p>Applications 2-Amino-4,5-dimethylthiophene-3-carbonitrile is a useful research chemical for organic synthesis and other chemical processes.<br>References Rahman, K. M. M., et al.: Pakistan J. Sci. Ind. Res., 46, 95 (2003); Madhavi, K., et al.: Res. J. Pharm. Biol. Chem. Sci., 8, 387 (2017)<br></p>

<p>Applications N-Hydroxybenzylamine Hydrochloride, is a versatile intermediate for the synthesis of various pharmaceutical compounds. It is used for the preparation of Ticagrelor (T437700) derivatives as novel antiplatelet agents.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007);<br></p>

<p>Applications Methyl 2-Amino-3,4,5-trimethoxybenzoate could be a constituent contributing to the aroma of green tea leaves.<br>References Hasegawa, T., et al.: J. Food Eng., 4, 10 (2014)<br></p>

<p>Applications Tris(N,N-dimethylaminopropyl)amine has been used in the synthesis of nickel(II) and cobalt(II) complexes with the propylene-bridged tripod ligand tris(3-dimethylaminopropyl)amine (donor set N4).<br>References Morassi, R., Dei, A.: J. Chem. Soc., 12, 2024 (1971)<br></p>

<p>Applications 2-(Tributylstannyl)-2-propen-1-amine (cas# 155258-22-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Cyclopentylmethanamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Aminothiophen-3-ol, is a heterocyclic building block used for the synthesis of various pharmaceutical compounds.<br></p>

<p>Applications DL-2-Amino-1-pentanol is a useful intermediate for organic synthesis. It is used in the preparation of amino-substituted pyrimidine derivatives and other aminoethanethiol derivatives with potential antiradiation properties.<br>References Yoo, K. H., et al.: Korean J. Med. Chem., 9, 83 (1999); Fernandez, S., et al.: Synthesis, 9, 713 (1991)<br></p>

<p>Applications 5-chloro-2,1,3-benzoxadiazol-4-amine (cas# 80277-04-9) is a useful research chemical.<br></p>

<p>Applications (benzyloxy)(methyl)amine (cas# 22513-22-0) is a useful research chemical.<br></p>

<p>Applications 4-(3-aminopropyl)-N,N-dimethylaniline (cas# 112103-97-6) is a useful research chemical.<br></p>

<p>Applications 2-((tert-bButoxycarbonyl)amino)-2-(hydroxymethyl)-4-(4-octylphenyl)butyl Acetate is the intermediate in the synthesis of Mono-O-acetyl Fingolimod TFA (F524600), which is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001). Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002). Mtaloubian, M., et al.: Nature, 427, 355 (2004)<br></p>

<p>Applications 4-amino-3-hydroxybenzenesulfonamide (cas# 3588-76-9) is a useful research chemical.<br></p>

<p>Applications 2-(Phenylamino)nicotinic Acid (cas# 16344-24-4) is a useful research chemical.<br></p>

<p>Applications (1S,2S)-1,2-Diphenyl-1,2-ethanediamine (cas# 29841-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(p-Fluorophenyl)-hydroxylamine, is a reactant used in various chemical synthesis, such as in preparation of spiro-isoxazoline and spiro-isoxazolidine derivatives of tomentosin.<br>References Zaki, M., et al.: RSC Advances, Vol. 7, Iss 11, P: 6523-6529 (2017);<br></p>

<p>Applications Amino-peg1-t-butyl Ester is a reagent used in the preparation of β2 adrenergic receptor agonists and muscarinic receptor activity antagonists.<br>References Donald, D. K., et al.: PCT Int. Appl., WO 2011048409 A1 WO2010-GB51751 (2011)<br></p>

<p>Applications 6-(4-Phenylbutoxy)-1-hexanamine is an intermediate in the synthesis of salmeterol (S090100), a structural analog of Albuterol (A514500).<br>References Goswami, J., et al.: Tetrahedron. Asym., 12, 3343 (2002);<br></p>

<p>Applications Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optically degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.<br>References Calderon, M. et al.: Macromol. Sym., 258, 53 (2007); Kostiainen, M.A. et al.: Chem. Eur. J., 16, 6912 (2010); Klein, E. et al.: Angew. Chem. Int. Ed., 44, 298 (2005);<br></p>

<p>Applications 7-Amino-alpha-tetralone<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-(4-Bromophenyl)-[1,1-biphenyl]-4-amine is a useful reagent for preparing carbazole and dibenzofuran-linked tertiary arylamine compounds, which may improve electroluminescent properties.<br>References Ito, H., et al.: Jpn. Kokai Tokkyo Koho (2020), JP 2020093979 A<br></p>

<p>Applications 3-Aminomethylbenzoic acid<br></p>

<p>Applications n-Dipropylamine is a useful reagent for the preparation of perylene derivatives for photosensitive fluorescent resins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jang, H., et al.: PCT Int. Appl. (2021), WO 2021010703 A1<br></p>

<p>Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-(Aminomethyl)furan-2-carboxylic Acid Hydrochloride is a useful reagent in the preparation of novel heteroaromatic substrates of GABA aminotransferase.<br>References Hawker, D. D., et al.: Bioorg. Med. Chem., 20, 5763 (2012)<br></p>

<p>Applications 3-[benzyl(methyl)amino]propane-1,2-diol (cas# 60278-98-0) is a useful research chemical.<br></p>

<p>Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.<br></p>

<p>Applications N10-(Ethoxycarbonyl)tryptamine is an intermediate in the synthesis of N-Methyltryptamine-d3 (M331922), which is a labeled N-Methyltryptamine, a N-monomethylated derivative of tryptamine. N-Methyltryptamine, unlike its unmethylated counterpart, does not produce any psychoactive effects. High levels of N-Methyltryptamine have been found in cisternal cerebrospinal fluid of patients with acute paranoid schizophrenia.<br>References Schmid, C. et al.: J. Neurosci., 30, 13513 (2010); Uebelhack, R. et al.: Biomed. Biochim. Acta, 42, 1343 (1983);<br></p>

<p>Applications 3-​[[[3-​(Aminomethyl)​-​5-​methyl-​1-​oxohexyl]​amino]​methyl]​-​5-​methyl-hexanoic Acid is an intermediate in synthesizing 4,9-Diisobutyl-1,6-diazecane-2,7-dione (D456300), an impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>

<p>Applications In mammals, metabolism of 3-aminopropionitrile leads to release of cyanide ions. Metabolic activity is localized in the microsomal fraction of the liver, and is believed to proceed through a free-radical pathway.<br>References Fernandez, G., et al.: Vet. Human Toxicol., 33, 321 (1991)<br></p>

<p>Applications 2,3-Dimethyl-2H-indazol-6-ylamine is a reagent used in the synthesis of Pazopanib derivatives as antitumor agents.<br>References Jia, Y., et al.: Chem. Biol. Drug Design, 83, 306 (2014)<br></p>

<p>Applications 6-​Amino-​5-​nitrochromen-​2-​one is a reagent used in the synthesis of pyranopyridinediones.<br>References Khan, M. et al.: J. Pure App. Sci., 22, 37 (2004);<br></p>

<p>Applications 1,11-Diaminoundecane<br></p>

<p>Applications Azido-PEG1-amine (cas# 464190-91-8) is a useful research chemical.<br></p>

<p>Applications Trimethyl (2-N-t-Butoxycarbonylamino)ethylammonium Bromide is a compound useful in organic synthesis.<br></p>