Amines

<p>4-Amino-3-methoxypyridine (4AMMP) is a naturally occurring amino acid that can be found in the nuclei of innervated tissues. It is an inhibitor of the enzyme tyrosine hydroxylase and inhibits the synthesis of catecholamines. The concentration of 4AMMP in blood was measured by radioactivity. This agent has been used for studies on the thalamic nucleus and cortex, as well as for measuring catecholamine levels in tissue homogenates.</p>

<p>DDAVP is an analogue of vasopressin, which belongs to the class of inositol phosphates. It is a potent agonist for the V1 receptor and has a higher affinity for this receptor than vasopressin. DDAVP also has antagonist properties at the V2 receptor. The biological activity of DDAVP is mediated by its ability to increase phospholipase A2 activity and cause the release of arachidonic acid from membrane phospholipids. This activation causes an increase in prostaglandin synthesis, leading to increased vascular permeability and hypotension. DDAVP may also have antidiuretic effects due to its antagonism of oxytocin receptors.</p>

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<p>Desmopressin is a synthetic analogue of vasopressin, which is used to treat disorders associated with insufficient secretion of vasopressin. It has been shown that desmopressin binds to the vasopressin V2 receptor subtype and stimulates the release of arginine-vasopressin in corticotropin-releasing hormone (CRH)-treated rat pituitary cells. This stimulation was mediated by a residue on the Cys1,b-cyclohexyl residue. The binding of desmopressin to this site was demonstrated in vitro using binding experiments on rat brain synaptosomes. Desmopressin has also been shown to stimulate ovulation in rats and humans, and it has been shown to be effective for treating nocturnal enuresis in children.</p>

<p>O-(2-Aminoethyl)-O’-(2-azidoethyl)triethylene glycol is a programmed cell death inducer that belongs to the family of adp-ribose signaling molecules. It is active in inducing apoptosis and cellular death in both cancer cells and noncancerous cells. This molecule has been shown to be cytotoxic against breast cancer cells from MDA-MB-231 cell lines and also induces apoptosis in these cells.</p>

<p>Pyrithiamine is an antimicrobial agent that inhibits the growth of bacteria by disrupting the disulfide bond between two cysteine residues. It has been shown to inhibit the formation of bacterial spores, which are resistant to many antibiotics. Pyrithiamine also has antioxidant properties and can reduce oxidative stress in neurons, leading to neuronal death. This drug also has a strong effect on energy metabolism and may be used as a treatment for mitochondrial diseases.</p>

<p>3-(Boc-amino)pyridine is a glycine derivative with a trigonal, chelate ring. It can be hydrolyzed by acid to form 3-aminopyridine. 3-(Boc-amino)pyridine has been shown to react with trimethyltin chloride to form an intramolecular complex in the presence of alkyllithiums. This reaction proceeds through lithiation and methylation of the carboxyl group of 3-(Boc-amino)pyridine. The interaction between 3-(Boc-amino)pyridine and trimethyltin chloride forms an antiaromatic six membered ring that resembles a benzene molecule.</p>

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<p>2-Amino-6-(trifluoromethyl)benzothiazole is a new, optimised insecticide with alkylthio, halogen and alkoxy groups. It is highly toxic to insects and has been shown to be active against various species of Lepidoptera, Coleoptera and Diptera. 2-Amino-6-(trifluoromethyl)benzothiazole is also a broad spectrum contact insecticide that exhibits systemic properties. This insecticide can be used on plants, crops, livestock and pets.</p>

<p>Tetra-n-propylammonium hydrogen sulfate (TPAS) is a pharmaceutical dosage that consists of tetra-n-propylammonium ions and hydrogen sulfate anions. It has a diameter of about 2 nm, and can be detected by fluorescence techniques. TPAS has shown to have pharmacologic activities, including the ability to react with hydrogen fluoride in solution to form a precipitate that can be used as a sample preparation reagent. TPAS also has been shown to produce dehydrating effects on chloride in an alicyclic system.</p>

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<p>1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a lipid molecule that can induce phase transition in aqueous solutions. DLPE is an active ingredient in nonsteroidal anti-inflammatory drugs and has been shown to inhibit the activity of enzymes such as cyclooxygenase and lipoxygenase. DLPE also inhibits the growth of infectious organisms such as Escherichia coli and HIV by inhibiting receptor activity. DLPE binds to receptors on the surface of cells, which prevents these cells from releasing inflammatory cytokines.</p>

<p>RR,R)-(-)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine is a coordination compound that is used as a catalyst in organic chemistry. It has been shown to catalyze the reaction of benzaldehyde with nitroethane to give phenylamine. RR,R)-(-)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine also catalyzes the reaction of cyclohexanol with nitroethane to give phenylethylene. The selectivity of this catalyst depends on the site of adsorption and the ligand. This compound has been shown to be electrocatalytic by promoting the oxidation of anilines at a platinum electrode in water solution with an applied potential.</p>

<p>Intermediate in the synthesis of tofacitinib</p>

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