Ethers

<p>Applications 4-(2-(Methoxycarbonyl)phenoxy)benzoic Acid is an intermediate in the synthesis of Balsalazide (B116300) related compounds.<br></p>

<p>Applications 5-[3-(Trifluoromethoxy)phenyl-2-Furancarboxylic Acid is the structural analogue of 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid (T790925), a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.<br>References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)<br></p>

<p>Applications (3,3-diethoxypropyl)dimethylamine (cas# 16851-30-2) is a useful research chemical.<br>References Choi, G., et al.:Angew. Chem. Int. Ed., 57,6166(2018)<br></p>

<p>Stability Volatile<br>Applications Methoxytrimethylsilane (cas# 1825-61-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl 2-Acetamido-2-(Dimethoxyphosphoryl)Acetate (cas# 89524-99-2) is a useful research chemical.<br></p>

<p>Applications [(Methoxy)methyl]triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment.<br>References Sells, M., et al.: J. Virol., 62, 2836 (1988), Kaneko, S., et al.: J. Clin. Microbiol., 27, 1930 (1989), Baba, Y., et al.: Bioorg. Med. Chem., 13, 5164 (2005), Romero, M., et al.: Antiviral Res., 68, 75 (2005); Hirai, S. et al.: Tetrahedron Lett., 54, 1888 (2013); Xing, P. et al.: Synth., 45, 596 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Stability Hygroscopic<br>Applications [3-(3,4-dimethoxyphenyl)propyl](methyl)amine hydrochloride (cas# 83979-31-1) is a useful research chemical.<br></p>

<p>Applications Ethoxyacetic acid<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications o-Carbomethoxybenzyl Sulfonamide is a useful reactant in organic synthesis.<br>References Jiang, Lin, et al.: Youji Huaxue, 26(2), 203-206 (2006)<br></p>

<p>Applications 4,5-DIMETHOXY-2-NITROBENZAMIDE (cas# 4959-60-8) is a useful research chemical.<br></p>

<p>Applications 3,4-Dimethoxytoluene is a volatile flavor compound found is many substances such as boiled buckwheat flour, wild rice grain and tar of hickory wood smoke.<br>References Yajima, I., et. al.: Agr. Bio. Chem. 47, 729 (1983); Withycombe, D.A., et. al.: J. Agr. Food Chem., 26, 816 (1978); Hruza, D.E., et. al.: J. Agr. Food chem., 22, 123 (1974)<br></p>

<p>Stability Hygroscopic<br>Applications Ethyl 3,3-diethoxypropionate<br></p>

<p>Applications Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optically degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.<br>References Calderon, M. et al.: Macromol. Sym., 258, 53 (2007); Kostiainen, M.A. et al.: Chem. Eur. J., 16, 6912 (2010); Klein, E. et al.: Angew. Chem. Int. Ed., 44, 298 (2005);<br></p>

<p>Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.<br>References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)<br></p>

<p>Applications 1,3-Diacetoxy-2-(acetoxymethoxy)propane is a compound involved in the synthesis of Ganciclovir (G235000), an antiviral nucleoside analog structurally related to Acyclovir (A192400).<br>References Halloran, P.J. and Fenton, R.G.: Cancer Res., 58, 3855 (1998), Rubsam, L.Z., et al.: Cancer Res., 59, 669 (1999), Yamasaki, H., et al.: C.R. Acad. Sci. III, 322, 151 (1999)<br></p>

<p>Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.<br></p>

<p>Applications An intermediate for the preparation of (+/-)-Taxifolin.<br></p>

<p>Applications N-ethyl-3,4-dimethoxyaniline (cas# 32953-13-2) is a useful research chemical.<br></p>

<p>Applications 1-[2-Hydroxy-4,6-bis(ethoxymethoxy)phenyl]ethanone (cas# 128837-25-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Ethoxymethyl)furan (cas# 6270-56-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications B-[3-[[2-Hydroxy-3-[3-(triethoxysilyl)propoxy]propyl]amino]phenyl]boronic acid was prepared for the use as porous polymeric monolith for the specific capture of cis-​diol-​containing flavone under neutral condition.<br>References Pan, J., et al.: Chem. Eng. J., 317, 317-330 (2017);<br></p>

<p>Applications 2-(1,1-Dimethylethoxy)-1-propanol is a useful reagent for organic synthesis.<br></p>

<p>Applications An intermediate for the preparation of Terbutaline.<br></p>

<p>Applications Tetramethoxymethane has application within an electrolyte solution for the use of rechargeable lithium batteries. It has also been used as a reactant in the synthesis of novel anti-HIV-1 compounds.<br>References Cadger, T.G. et al.: Proc. Electrochem. Soc., 88, 699 (1988); Kazmierski, W.M. et al.: J. Med. Chem., 54, 3756 (2011);<br></p>

<p>Stability Hygroscopic<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)-benzoic Acid is a useful synthetic intermediate. It is an intermediate used to synthesize Jaboticabin (J210370) which is minor bioactive depside potent to treat chronic obstructive pulmonary disease.<br>References Wu, S., et al.: J. Agri. Food Chem., 61, 4035 (2013); Reynertson, K., et al.: J. Nat. Prod., 69, 1228 (2006)<br></p>

<p>Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-(Dimethoxyphosphoryl)acetic acid<br></p>

<p>Applications 3,4-Dimethoxybenzylamine (cas# 5763-61-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-[2-(2-azidoethoxy)ethoxy]ethanamine (cas# 166388-57-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl 2-Acetyl-4,4-dimethoxybutanoate is a useful reagent for organic synthesis.<br>References Herrmann, J. L., et al.: Tetrahedron Lett., 47, 4711 (1973)<br></p>

<p>Applications Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester is used in the discovery of a potent, selective and orally bioavailable dual CCR2 and CCR5 antagonist.<br>References Zheng, C., et al.: Bioorg. Med. Chem. Lett., 21, 1442-1446 (2011)<br></p>

<p>Applications Tetramethoxypropane is a useful synthetic intermediate. It can be used to synthesize various compounds such as diiodonoradamantane and Salicylates[e.g. Salsalate(S095700)].<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ioannou, S., et al.: Tetrahedron Lett., 51, 2671 (2010); Sher, M., et al.: J. Org. Chem., 72, 6284 (2007)<br></p>

<p>Applications 4,4-Dimethoxybutan-1-ol is a reactant used in the preparation of tetrahydropyranols and hydropyranooxepans.<br>References Hoffmann, R.W., et. al.: New J. Chem., 25, 102 (2001)<br></p>

<p>Applications 3,3-Diethoxy-1-propanol is used as a reactant in the synthesis of nanoparticles.<br>References Sumitani, Shogo, et al.: Reactive &amp; Func. Polymers, 71(7), 684-693 (2011);Kanakubo, Yurie, et al.: Colloids and Surfaces, B, 78(1), 85-91 (2010)<br></p>

<p>Applications 2,4,5-TRIMETHOXYBENZOIC ACID (cas# 490-64-2) is a useful research chemical.<br></p>

<p>Applications 4,4-Diethoxy-N,N-diethyl-1-butanamine is a useful reagent for the synthesis of amino acetals.<br>References Keglevic, D., et al.: Croat. Chem. Acta, 35, 175(1963)<br></p>

<p>Applications (3,5-Dimethoxyphenyl)acetonitrile (cas# 13388-75-5) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(2-(1,3-Dioxoisoindolin-2-yl)ethoxy)benzamide is an intermediate in the synthesis of Fluvoxamine Maleate (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.<br>References Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977); Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996); Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997); Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)<br></p>

<p>Applications Methoxy4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzenemethanol, is prepared synthetically from vanillin (V097500) with an intermediate of methoxy-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzaldehyde (M269710).<br>References Gowravarm, S. et al.: Adv. Synth. Catal., 343, 169 (2001)<br></p>

<p>Applications tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate has been used as a reactant in the preparation of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 with potential use in osteoarthritis therapy.<br>References Durham, T.B., et. al.: J. Med. Chem., 57, 10476 (2014)<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)benzeneethanamine is an intermediate used in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), which belongs to the class of adrenergic inhalants, selective β-2-adrenoreceptor agonists. S-(-)-Tretoquinol is used in the treatment of obstructive airway diseases. S-(-)-Tretoquinol is a bronchodilator.<br>References Meshi, et al.: Biochem. Pharmacol., 19, 2937 (1970), Satoh, et al.: Chem. Pharm. Bull., 19, 667 (1971),<br></p>

<p>Applications (3-Aminopropyl)trimethoxysilane is used in the synthesis of aspirin imprinted polymer on silica gel surface and appreciation on drug sustained release. Fluorine-doped; lectin functionalized ZnO nanoarrays as 3D nano-biointerface for bacterial detection.<br>References Lu, P., et al.: Gaofenzi Cailiao Kexue Yu Gongcheng, 33, 130 (2017); Zheng, L., Talanta, 167, 600 (2017)<br></p>

<p>Applications (6,7-dimethoxy-4-oxoquinazolin-3(4H)-yl)acetic acid (cas# 877140-09-5) is a useful research chemical.<br></p>

<p>Applications 2-((Tetrahydrofuran-2-yl)methoxy)phenoxy)tetrahydro-2H-pyran is an intermediate used in the synthesis of Bufetolol (B689435), a β-adrenergic blocking agent and it inhibits the activation of adenyl cyclase.<br>References Ikegami, K., and Imamura, H.: Yakugaku Zasshi 96, 614 (1976); Yamaji, A., et al.: Yakugaku Zasshi 105, 1179 (1985)<br></p>

<p>Applications 1,2,3-Trimethoxybenzene can be used for RSM-optimised slow pyrolysis of rice husk for bio-oil production.<br>References Das, S., et.al.: Energy, 225, 120161, (2021);<br></p>

<p>Applications 4-(Methoxycarbonyl)phenylboronic Acid is used in the synthesis and evaluation of several organic compounds including that of 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate which is a potent inhibitor of intracellular NAAA activity. Also used in the design and synthesis of BMS-955176 which is a potent, orally active second generation HIV-1 maturation inhibitor.<br>References Nuzzi, A., et al.: Eur. J. Med. Chem., 111, 138 (2016); Rogueiro-Ren, A., et al.: ACS Med. Chem. Lett., 7, 568 (2016);<br></p>

<p>Stability Hygroscopic<br>Applications [3-(Ethoxycarbonyl)propyl]triphenylphosphonium Bromide is a reactant used in the preparation of maresin 1, a potent anti-inflammatory and pro-resolving lipid mediator.<br>References Tungen, J.E., et. al.: Tetrahedron Lett., 56, 1843 (2015)<br></p>

<p>Applications 2-(Methoxyimino)-3-oxo-butanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of Cefotaxime Bromoacetyl Analogue (C242940), which is an impurity of Cefotaxime (C242950), a broad spectrum third generation cephalosporin antibiotic.<br>References Wise, R., et al.: Antimicrob. Agents Chemother., 14, 807 (1978), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 11, 139 (1982),<br></p>

<p>Applications Tetraethyl Orthocarbonate is used in the synthesis of chemokine receptor-5 inhibitors against HIV-1. Also used in the synthesis of benzobisoxazoles used in the preparation of organic semiconductors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kazmierski, W. et al.: J. Med. Chem., 54, 3756 (2011); Mike, J. et al.: Org. Lett., 10, 4915 (2008);<br></p>

<p>Applications 2-Ethoxy-4-ethoxysulfonylbenzoic Acid is a derivative of Methyl 2-Ethoxybenzoate (M220113), a useful chemical reagent, used in the synthesis and antibacterial triazoles and oxadiazoles, as well as sulfonamide compounds.<br>References Shi, Z. et al.: Compt. Rend. Chim., 18, 1320 (2015);<br></p>

<p>Applications 4,4'-Dimethoxystilbene is an intermediate in the synthesis of nonsteroidal, selective estrogen receptor modulator (SERM), Raloxifene (R100000).<br>References Liu, H., et al.: Chem. Res. Toxicol., 18, 162 (2005); Chen, Z., et al.: J. Org. Chem., 65, 8811 (2000);<br></p>

<p>Applications 4,4'-Dimethoxydiphenylamine is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4'-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.<br>References Kel'man, G.Y. et al.: Kauch. Rez., 26, 28 (1967); Sofuni, T. et al.: Mutat. res. Gen. Toxicol. Test., 24, 175 (1990);<br></p>

<p>Applications 4,5-Dimethoxy-2-nitrobenzoic Acid (cas# 4998-07-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.<br>References Ye, X. et al.: Zhong. Yao. Xuax. Zaz., 20, 106 (2010);<br></p>

<p>Applications 1,4-Dimethoxybenzene is a useful chemical in organic synthesis.<br>References Digwal, Chander S., et al.: Asian J. of Org. Chem., 7(5), 865-869 (2018);Cai, Zhi-Bin, et al.: RSC Advances, 6(52), 46853-46863 (2016);Lin, Qi, et al.: Soft Matter, 13(39), 7222-7226 (2017)<br></p>

<p>Applications 2,2-Diethoxy-N-ethylethanamine is used in the preparation of 1-substituted-2-mercaptoimidazoles with antithyroid activity.<br>References Jones, R.G.J. Am. Chem. Soc., 71, 4000 (1949)<br></p>

<p>Applications 4,4'-Dimethoxybenzhydrol acts as a reagent in the preparation of aryloxyacetamide derivatives and their biological activity as neuroprotective agents. Preparation and anticancer activity of quebecol and analogs.<br>References Zhong, Y., et al.: Bioorg. Med. Chem. Lett., 26, 2526 (2016); Pericherla, K., et al.: Bioorg. Med. Chem. Lett., 23, 5329 (2013)<br></p>

<p>Impurity Lubiprostone Impurity VI<br>Applications 7-((1R,2R,3R)-3-(cyclohexylmethoxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid is a useful chemical reagent.<br></p>

<p>Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.<br>References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);<br></p>