Ethers

<p>Intermediate in the synthesis of osimertinib (AZD9291)</p>

<p>Candesartan is a selective angiotensin II receptor antagonist that inhibits the binding of angiotensin II to its receptors, which in turn decreases the activity of angiotensin-converting enzyme. Candesartan cilexetil is an ester prodrug that has been shown to be effective in the treatment of high blood pressure. In the crystalline form, candesartan cilexetil is a white powder with a melting point of 130–135 °C and a solubility in water of &gt;1 g/L. The molecular weight of candesartan cilexetil is 393.8 g/mol and it has a molecular formula C17H21NO2S. The chemical structure consists of two benzimidazole rings coupled together through an ethyl-2-ethoxy linker and attached to a carboxylate group on one end and an amide group on the other</p>

<p>1-(3-Chloro-4-methoxyphenyl)acetone is a white solid with a melting point of 60-61°C. It is a versatile building block that can be used in the synthesis of complex compounds and as a reaction component for the preparation of speciality chemicals. 1-(3-Chloro-4-methoxyphenyl)acetone has been studied extensively as an intermediate for the synthesis of pharmaceuticals, including acetaminophen and amoxicillin. This compound also has uses in research laboratories and as a reagent in organic synthesis.</p>

<p>2-Amino-5-methoxypyridine (2AM5MP) is a synthetic compound that is used to study the nicotinic acetylcholine receptor. It has been shown that 2AM5MP can be used as an agonist for the nicotinic acetylcholine receptor, which may be due to its ability to act as a substrate for amine oxidase. This compound has been shown to have anti-cancer properties and fluoresce when exposed to positron emission tomography (PET) scans. The anti-cancer effects of 2AM5MP are thought to be due to its ability to inhibit cancer cell proliferation and induce cancer cell apoptosis.</p>

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<p>Methyl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate is a natural compound, which belongs to the group of ferulate esters. It has been shown that methyl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate inhibits the activity of esterases, which are enzymes that hydrolyze esters. This inhibition leads to an accumulation of ferulic acid in the blood, which is associated with bowel disease. Methyl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate has been shown to be effective against murine hepatoma cells and polymorphonuclear leucocytes, which are white blood cells that can be found in the blood and other tissues. The inhibitory effect on these cells may be due to its ability to bind to ferulic acid and caffeic acids.</p>

<p>Used in treatment of nonspecific ulcerative colitis</p>

<p>3'-Hydroxy-4'-methoxyacetophenone is a chemical compound with the molecular formula CHO and it belongs to the group of bisbenzylisoquinoline alkaloids. It is a white crystalline powder that has a dry weight of 155.2g/mol and melting point of 154-158°C. 3'-Hydroxy-4'-methoxyacetophenone is used as an intermediate in the synthesis of other chemicals, such as methyl transferase inhibitors like metronidazole or oxidative stress agents like benzoquinones. 3'-Hydroxy-4'-methoxyacetophenone can be found in bowel disease patients, where it may be produced by bacteria in the gut. This chemical also has UV absorption properties and can be used as a sample preparation agent for hydroalcoholic samples.</p>

<p>Methyl 3,5-dichloro-4-methoxybenzoate is a fine chemical and useful building block for research chemicals. It belongs to the class of speciality chemicals and can be used as a reagent in organic synthesis. Methyl 3,5-dichloro-4-methoxybenzoate is a versatile building block that has been reported in the synthesis of many complex compounds. This compound can also be used as an intermediate or scaffold for medicinal chemistry applications.</p>

<p>5-Chloro-2,4-dimethoxyaniline (5-CDA) is a crystalline solid that belongs to the amine class of chemical compounds. It is used in the production of polyhalogenated anilines and nitrosamines, which are known carcinogens. 5-CDA has been shown to be toxic to animals at high doses and can cause health effects such as irritation of the eyes, skin, and respiratory tract; central nervous system depression; and gastrointestinal disturbances. The toxicity of this compound is related to its ability to form nitrosamines when it comes into contact with nitrite or other N-nitroso compounds. 5-CDA is also present in wastewater effluents from paper mills and agricultural runoff from triticum aestivum fields.</p>

<p>3-(2-(3,4-Dimethoxybenzoyl)-4,5-dimethoxyphenyl)pentan-2-one is an alkylene that is produced by the reaction of hydrazine with 2,3,4-trimethoxybenzoic acid. This molecule has been shown to have anxiolytic properties in animal studies and hydrolyzes to form ethylene glycol. 3-(2-(3,4-Dimethoxybenzoyl)-4,5-dimethoxyphenyl)pentan-2-one also has a hydrolysis product of tofisopam. Tofisopam is an organic acid that has been used as an antidepressant for the treatment of anxiety disorders.</p>

<p>2-Amino-a-(methoxyimino)-4-thiazoleacetic acid is a reaction product of cefotaxime and n-dimethyl formamide. It has been shown to be an effective agent for the treatment of wastewater with a high organic content. 2-Amino-a-(methoxyimino)-4-thiazoleacetic acid also reacts with chloride ions to form cleavage products that are soluble in water, making it an ideal choice for wastewater treatment. This compound is not toxic and can be used as a drug to treat patients with infections caused by bacteria resistant to other antibiotics. 2-Amino-a-(methoxyimino)-4-thiazoleacetic acid binds to mismatched base pairs in DNA, inhibiting DNA synthesis and causing cell death by apoptosis.</p>

<p>6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carbolin-1-one is a β-carboline alkaloid that is structurally related to harmaline and tetrahydroharmine. It has been shown to have antidepressant activity in animals. 6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carbolin-1-one was analyzed by GC/MS and found to be present in the leaves of plants from the genus Tetraclinis. 6MHBC was also identified as a metabolite of diazepam in rat urine after administration of a single oral dose of 10 mg/kg diazepam. The observed β carboline metabolite was determined to be 6MHBC.</p>

<p>4-Methoxyphenyl boronic acid is a molecule with a hydroxyl group and a boronic acid. It is synthesized by reacting biphenyl with trifluoroacetic acid in the presence of sodium carbonate and palladium-catalyzed coupling. 4-Methoxyphenyl boronic acid has shown to bind to the receptor for fatty acids, which may be due to its structural similarity to p-hydroxybenzoic acid. The protonated form of this molecule has been shown to react with an electrophilic carbon atom and an electron-deficient alkyl or vinyl halide, resulting in ring formation. This reaction is known as the Suzuki coupling reaction.</p>

<p>Potassium 4-methoxycinnamate is a fine chemical that is used as a versatile building block in the synthesis of complex compounds. It can be used in research and as a reagent or speciality chemical. It is also a useful building block for high quality, useful intermediate, and reaction component. Potassium 4-methoxycinnamate can be used as a scaffold to synthesize compounds with diverse applications such as pharmaceuticals, polymers, and agrochemicals.</p>

<p>5-Methoxy-3,4-dihydro-2H-pyrrole is a chemical compound that contains a pyrrole ring. It can be found in the form of dehydrogenation and intramolecular hydrogen. 5-Methoxy-3,4-dihydro-2H-pyrrole has been shown to have antibacterial effects against Mycobacterium tuberculosis and other bacteria. 5-Methoxy-3,4-dihydro-2H-pyrrole also reacts with nitroacetate to form an aziridine, which is an intermediate in the synthesis of several pharmaceuticals. This chemical compound is used in the preparation of bipyrrole compounds such as naphthalene and alicyclic compounds such as nitrophenols.</p>

<p>3-(3,5-Dimethoxyphenyl)propionic acid methyl ester is a reagent that is used as a reactant in organic synthesis. It is also useful as a scaffold for the synthesis of heterocycles and other complex compounds. 3-(3,5-Dimethoxyphenyl)propionic acid methyl ester is used in research chemical synthesis and as a versatile building block for the production of fine chemicals. This chemical can be used to create products such as pharmaceuticals, pesticides, and cosmetics.</p>

<p>N-(2-Aminoethyl)-3-(trimethoxysilyl)propylamine (NAP) is a cationic surfactant that is used as a fluorescent probe to study the binding of proteins to cell surface integrin receptors. The adsorption mechanism is based on the interaction between the hydrophobic parts of the protein and the hydrophobic parts of NAP. This interaction leads to an increase in the concentration of NAP at the interface and thus an increase in fluorescence. NAP has been shown to bind human serum albumin, fatty acids, and monoclonal antibodies with high affinity. It also has been shown to bind to plasma proteins through hydrogen bonding. The optimum concentration for NAP adsorption is 1mM.</p>

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<p>2-[2-Trifluoroethoxyphenoxy]ethyl methanesulfonate is a research chemical that is commonly used in the synthesis of enantioselective compounds. It has been clinically studied for its potential use in the treatment of prostatic hyperplasia, a condition characterized by an enlargement of the prostate gland. This compound has shown promising results in inhibiting the growth of prostatic cells and reducing symptoms associated with hyperplasia. Its enantioselective properties make it an ideal candidate for targeted therapy, allowing for more precise and effective treatment options. Researchers continue to explore the potential applications of 2-[2-Trifluoroethoxyphenoxy]ethyl methanesulfonate in various fields, including medicine and pharmaceuticals.</p>

<p>4-Chloro-2-(trifluoromethoxy)aniline is a fine chemical that is used as a building block in the synthesis of other chemicals, such as pharmaceuticals and agrochemicals. It is also used in research as a reagent for organic synthesis and as a speciality chemical. 4-Chloro-2-(trifluoromethoxy)aniline has versatile applications in the manufacture of complex compounds, intermediates, and scaffolds.</p>

<p>Please enquire for more information about 1-(2,4-Dihydroxy-5-methoxyphenyl)-2-(4-hydroxyphenyl)-3,3-dimethoxy-1-propanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>4-Amino-3-methoxypyridine (4AMMP) is a naturally occurring amino acid that can be found in the nuclei of innervated tissues. It is an inhibitor of the enzyme tyrosine hydroxylase and inhibits the synthesis of catecholamines. The concentration of 4AMMP in blood was measured by radioactivity. This agent has been used for studies on the thalamic nucleus and cortex, as well as for measuring catecholamine levels in tissue homogenates.</p>

<p>Bexagliflozin is a drug that is used to treat type II diabetes in adults. It helps to control blood sugar levels by inhibiting the enzyme DPP-IV and increasing insulin release from the pancreas. Bexagliflozin has been shown to be effective in lowering blood sugar levels in patients with chronic kidney disease and cancer, as well as those with a body mass index (BMI) of 30 or higher. This drug is an oral hypoglycaemic agent that can be used for diagnostic purposes. It has also been shown to be clinically effective for the treatment of diabetic nephropathy and diabetic retinopathy. The enantiomers of bexagliflozin can be differentiated according to their pharmacological properties, which may allow for more targeted therapy.</p>

<p>3,5-Diiodo-4-methoxybenzhydrazide is a high quality chemical that is useful in the preparation of complex compounds. This compound has been shown to be an excellent reagent and useful intermediate for the synthesis of various fine chemicals. It has been used as a precursor for the production of the antiviral drug Tamiflu, among other pharmaceuticals. 3,5-Diiodo-4-methoxybenzhydrazide is also a versatile building block that can be used in research or as a reaction component in organic synthesis.</p>

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<p>2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide is a drug that has been used to treat a variety of diseases and conditions. It is an alpha adrenergic agonist that works by stimulating the alpha receptors in the body, which increase blood pressure and improve blood flow. This drug also has significant effects on energy metabolism, including the production of ATP. 2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide is used to treat patients with congestive heart failure who are taking low doses of midodrine hydrochloride or nonsteroidal antiinflammatory drugs.</p>

<p>Please enquire for more information about 2-Chloromethyl-4-(3-methoxypropoxy)-3-methylpyridine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-(3-Bromo-4-hydroxy-5-methoxyphenyl)acrylic acid is a polyphenol that can be found in plants and food. It has been shown to have antimicrobial properties against certain bacteria and fungi, such as Staphylococcus aureus, Clostridium perfringens, and Candida albicans. 3-(3-Bromo-4-hydroxy-5-methoxyphenyl)acrylic acid is synthesized by means of the condensation of p-coumaric acid with acrylic acid in the presence of a base catalyst. This compound undergoes biotransformations such as hydroxylation and oxidation to form 3-(3,4′-dihydroxyphenyl)acrylic acid (DHPAA). The compound is also able to react with other phenolic compounds such as cinnamic acid under certain conditions.</p>

<p>7-Methoxy-4-(trifluoromethyl)coumarin is a potent and selective aromatase inhibitor. It inhibits the activity of the enzyme, which converts testosterone to estradiol. The inhibition of this enzyme may be beneficial in the treatment of breast cancer. This compound has also been shown to inhibit the activity of P450 enzymes and coumarin derivatives, which are involved in drug metabolism and detoxification.</p>

<p>N-(4-Methoxybenzylidene)-4-butylaniline is an organic compound that belongs to the group of liquid crystals. It has been used in the study of phase transitions and thermal properties. The melting point of N-(4-methoxybenzylidene)-4-butylaniline is between -80 and -90 °C, depending on the solvent. This compound has a low proton affinity, but it can be oxidized to form a radical cation.</p>

<p>2-Methoxy-6-picolinic acid (2MPA) is a picolinate that has been shown to be an effective catalyst for the conversion of alcohols into allylic alcohols. 2MPA is able to catalyze the reaction by abstracting hydrogen from the carbonyl group, and then adding it to the adjacent carbon. This reaction can produce peroxide as a byproduct, which is subsequently hydrolyzed to form water and alcohol. The β-unsaturated carbonyl group of 2MPA provides additional stability for this catalytic process.<br>2MPA can also be used as a catalyst in other reactions, such as the oxidation of benzylic alcohols with hydrogen peroxide to form benzylic carbonyl compounds.</p>

<p>N-Methoxymethyl-N-(trimethylsilylmethyl)benzylamine is a chiral, electron deficient reagent that reacts with aldehydes and boronic esters to form products with high chemical yields. This compound can be used as a catalyst for acylation reactions, such as the synthesis of p-nitrophenol. N-Methoxymethyl-N-(trimethylsilylmethyl)benzylamine is synthesized by the reaction of trifluoroacetic acid and an amine, followed by chloroformate displacement. The product is then reacted with acylating agents in the presence of catalysts.</p>

<p>Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzylpyrrolidinium is a natural compound that has been isolated from the Indian Ocean sea hare Dolabella auricularia. It has shown significant cytotoxicity against cancer cells as well as significant immunosuppressive activities in animals. Dolastatin 15 is an analog of dolastatin 10 and has been shown to be active against hepatitis B and C virus. It also has antiinflammatory properties and may be effective in combating autoimmune diseases. The synthesis of this compound is an asymmetric synthesis with a hydroxyl group on one side of the molecule and an amide on the other side.</p>

<p>2-Amino-2-oxoethoxy)acetic acid is a product that can be used as a transport agent in the process of extracting glycosides. It has been shown to have strong adsorption properties and is able to extract glycosides from plant material. 2-Amino-2-oxoethoxy)acetic acid has a high affinity for calcium, which is an important component in the adsorption mechanism.</p>

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<p>Tetrakis(methoxymethyl)glycoluril is a cross-linking agent that can be immobilized on various surfaces, including polyvinyl and magnesium oxide. Tetrakis(methoxymethyl)glycoluril is a water soluble molecule that has been used to coat the surface of optical fibers in order to prevent light scattering. This molecule has also been used as a coating for photomasks in order to control the patterning of thin films, such as polymers or photoresists. Tetrakis(methoxymethyl)glycoluril can be synthesized by reacting magnesium oxide with chloromethyl ethers at high temperatures in the presence of phosphorus pentoxide. The reaction produces an intermediate which reacts with deionized water to yield tetrakis(methoxymethyl)glycoluril.</p>

<p>P-Methoxybenzylmercaptan is an inhibitor of protein synthesis. It binds to the active site of the enzyme ribonuclease A, which is involved in the processing of messenger RNA. P-Methoxybenzylmercaptan also inhibits other enzymes such as alkaline phosphatase and esterases. It has been shown to be effective against HIV infection. This compound can be used for chemical ligation reactions and as a cell culture medium additive, as it protects cells from oxidation and provides a more acidic environment. P-Methoxybenzylmercaptan has been shown to bind to amines and is being investigated for its use in drug development.</p>

<p>7,9-Dimethoxycarbonyl-2-ethoxycarbonyl-1H-pyrrolo-[2,3-f]quinoline-4,5-dione is a chemical compound that is used as an intermediate for research chemicals. It has a CAS number of 80721-47-7 and is classified as a fine chemical with the Chemical Abstracts Service (CAS) classification code of 3272. This compound is a versatile building block that can be used in the synthesis of other compounds. 7,9-Dimethoxycarbonyl-2-ethoxycarbonyl-1H-pyrrolo-[2,3f]quinoline 4,5dione can be used to produce high quality products.</p>

<p>2-Bromo-4,5-dimethoxybenzoic acid is a synthetic compound that belongs to the group of anticancer drugs. It is a potent inhibitor of mitochondrial membrane depolarization and has been shown to inhibit tumor growth in vivo. 2-Bromo-4,5-dimethoxybenzoic acid also induces cell death by demethylation and hydroxylation of DNA, leading to apoptosis. This compound is synthesized by reacting 3,4-dihydroxybenzoic acid with bromine and potassium hydroxide. Surrogates such as amides are used for this synthesis because the original product is not stable enough. Protocatechuic acid can be produced from 2-bromo-4,5-dimethoxybenzoic acid through hydrolysis.</p>

<p>2-Fluoro-6-methoxybenzonitrile (2FMN) is a compound that is used as a starting material for the synthesis of other pharmaceuticals. It has been shown to bind to the acetylcholine receptor by using vibrational spectroscopy and functional theory. It also has been shown to be an effective chemokine inhibitor. Computational methods were used to optimize 2FMN's binding affinity for the acetylcholine receptor, and it was found that 2FMN binds with a dipole orientation in order to increase its binding affinity.</p>

<p>2-(2-Ethoxyphenoxy)ethyl bromide is a substance that is found as an impurity in the drug sulphonamide. It has been shown to be an optical isomer of methanol and ethanol, which have base form. The substance crystallizes in the form of white needles and its base form is tamsulosin hydrochloride. It has been used as a reagent for organic chemistry reactions, such as recrystallization, and as an impurity in organic solvents.</p>

<p>Methoxyacetaldehyde diethyl acetal is a viscous liquid with a low vapor pressure. This substance is stable at high temperatures and has a high resistance to chemical interactions. It is also hydrophobic in nature. Methoxyacetaldehyde diethyl acetal has been shown to interact with the aminoglycoside antibiotics, erythromycin, streptomycin, and neomycin. The interaction of this substance with these antibiotics may be due to the fact that it has proton resonances similar to those of amino acids, as well as its ability to form hydrogen bonds with the antibiotic molecules. Methoxyacetaldehyde diethyl acetal also interacts with triethyl orthoformate, which can lead to the formation of an ester bond between them.</p>

<p>4-Chloro-6,7-dimethoxyquinoline (4C6DMQ) is a potent inhibitor of the growth of prostate cancer cells. 4C6DMQ is an analog of chloropropyl chloride, which inhibits the growth of epidermal growth factor receptor (EGFR). The binding site for 4C6DMQ on EGFR is the same as that for chloropropyl chloride. 4C6DMQ inhibits EGFR by preventing the activation of downstream signaling cascades, leading to a decrease in cell proliferation and tumor size. The IC50 values for 4C6DMQ are approximately 10 times higher than those for chloropropyl chloride. This drug has been shown to be more potent than other inhibitors of EGFR such as erlotinib and gefitinib.</p>

<p>5-Fluoro-2-methoxyphenylacetone is a chemical with a wide array of applications in research and industry. It is a versatile building block, useful intermediate, and reagent for organic synthesis. This compound has been used as a starting material in the synthesis of other compounds. CAS No. 1017082-10-8</p>

<p>5-(Difluoromethoxy)-2-mercaptobenzimidazole is an organic solvent that is used in the crystallization process of pantoprazole, a benzimidazole derivative. It is also used as a corrosion inhibitor and pump inhibitor in analytical chemistry. The purity of 5-(difluoromethoxy)-2-mercaptobenzimidazole can be determined by chromatographic methods or by the use of analytical chemistry. Impurities may be genotoxic and include reactive impurities such as thiourea and 2-thiouracil. These impurities are removed during the synthetic process to produce 5-(difluoromethoxy)-2-mercaptobenzimidazole. This drug substance has been found to inhibit DNA polymerase activity in vitro, but its effects on human cells have not been studied.</p>

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