Ketones

<p>Applications Cyclohexyl-1-cyclohexenyl Ketone is used in the preparation of enones by nickel-catalyzed carbonylative Negishi cross-coupling.<br>References Wang, Q., et al.: Tetrahedron Lett., 49, 2916-2921 (2008)<br></p>

<p>Applications Cyclopentyl Phenyl Ketone is used in the preparation of ortho-arylated compounds and phenanthrones by palladium-catalyzed chelation-assisted C-H activation of Cyclopentyl Phenyl Ketone.<br>References Gandeepan, P., et al.: J. Am. Chem. Soc, 132, 8569 (2010)<br></p>

(11β)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione is a chemical compound that can be used as a building block in the synthesis of other chemicals. It is structurally related to progesterone and has been found to have antiandrogenic properties. This product can also be used as a reagent or speciality chemical in research. It is high quality and versatile. (11β)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna 1,4,16 triene 3,20 dione has been shown to have an effect on the body's reproductive system by binding to the androgen receptor.

14H-Benz[4,5]isoquino[2,1-a]perimidin-14-one is an organic compound with a molecular weight of 296.26 g/mol. It has a terminal alkynes group and two anthracene groups that are joined by a cyclic hydrocarbons skeleton. This molecule can be used as a polymerization monomer to produce polymers with high thermal expansion coefficients in the range of 10–30 ppm/°C. 14H-Benz[4,5]isoquino[2,1-a]perimidin-14-one has been shown to have an active oxygen species that reacts with metal surfaces at elevated temperatures. It also undergoes reactions with other molecules in the presence of light or radiation and is soluble in organic solvents such as acetone or cyclohexane. The melting point of this molecule is between 220–230 °C and its boiling point is between 260–270

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<p>1-(4-Morpholin-4-ylphenyl)ethanone is a compound that has been shown to interact with the cox-1 enzyme. This interaction can be seen in the functional theory, which states that the rate of intramolecular hydrogen transfer is dependent on the temperature and cox-1 concentration. This inhibition of cox-1 by 1-(4-morpholin-4-ylphenyl)ethanone leads to an antibacterial effect and may be due to its ability to inhibit bacterial growth by disrupting DNA replication. The molecular modeling technique was used to determine the relationship between 1-(4-morpholin-4-ylphenyl)ethanone and cox-1. The dipole moment of this molecule was determined using various alkyl substituents, which have been found to have an inhibitory effect on cox-1. These results are consistent with those obtained from an experiment using carrageenan, which also showed</p>

p-Nitrobenzyl 6-(1'-hydroxyethyl)-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate is a drug substance that is used in the manufacture of carbapenem antibiotics. It can be detected by a chloride ion chromatographic method, and the detection limit is 0.5 mg/L in the presence of zinc powder as a modifier. This material is used to prepare carbapenems using an analytical method that includes reaction monitoring by optical rotation, diastereomer chromatography, and transfer.

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<p>Spiro[4.5]decan-6-one is a spirocyclic compound that belongs to the class of dienones. It is postulated to be synthesized from the condensation reaction of an imidazole and a cyclic ketone. This compound was originally isolated as a product in the crystallization process of zirconium dichloride, which was used in the immobilization of enzymes for biofuel production. Spiro[4.5]decan-6-one has been shown to be catalysed by trifluoride, which may be due to its natural products activity.</p>

<p>2,2,5,5-Tetramethyldihydrofuran-3(2H)-one is an organic compound that is classified as a heterocyclic compound. This substance has been shown to be a good mercurial reagent and can be used for the synthesis of polycyclic compounds. 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one has been shown to form a dimer with sulfuric acid in the presence of polyphosphoric acid. It also reacts with ethers to form sulfates and furans.</p>

<p>4-Hydroxy-3-methoxyphenylacetone is a natural compound that is found in lignin and has been studied as a potential treatment for congestive heart failure. The compound has been shown to inhibit the activity of enzymes involved in the transfer reactions of bacterial cells. It also reduces the production of acetate, which is used by bacteria for growth. 4-Hydroxy-3-methoxyphenylacetone has been found to be nontoxic to mice at doses up to 10 g/kg. This study also showed that 4-hydroxy-3-methoxyphenylacetone had no effect on enzyme activities in rat liver mitochondria or rat brain synaptosomes.</p>

<p>5b-Pregnan-3a-ol-20-one is a natural product that belongs to the group of steroids. It has been shown to inhibit the polymerase chain reaction in animals. The drug also inhibits pain and has been shown to be effective in models of epilepsy. 5b-Pregnan-3a-ol-20-one binds to DNA, preventing transcription and replication. It also stabilizes the surface of cells, which may be important for its uptake by cells. This compound interacts with Tlr4, which may activate immune cells and lead to seizures. 5b-Pregnan-3a-ol-20-one is oxidized by cytochrome P450 enzymes, leading to the production of hydrogen peroxide and formation of a carbonyl group on the molecule.</p>

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<p>3-Phenylacetylamino-2,6-piperidinedione is a trifluoroacetate analog of the amino acid phenylalanine. It has been shown to be effective against cancer cells. 3-Phenylacetylamino-2,6-piperidinedione inhibits protein synthesis in tumor cells and is used as an antiestrogen in clinical studies. The hydroxyl group on the 3rd carbon atom makes this compound more acidic than its parent compound, 2,6-piperidinedione. This analog also has a high affinity for cancer tissues and urine samples. Treatment with this drug inhibits the growth of carcinoma cell lines MCT7 and MCF7.</p>

Vanillylideneacetone (VDA) is a natural compound that belongs to the class of phenylethanoids. It has been shown to have anti-inflammatory properties, which may be due to inhibition of prostaglandin synthesis. VDA also exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as some fungi and yeast. In vitro antifungal activity has been observed in human serum, cell lysis with the presence of trypsin, and cytotoxicity in carcinoma cell lines. Toxicological studies have shown no adverse effects on locomotor activity or carcinogenicity at high doses.

1,5-Bis(4-hydroxyphenyl)pentane-1,5-dione is a fine chemical that can be used as an intermediate in the synthesis of other compounds. It is also a useful building block for the synthesis of complex compounds. This compound can be used as a reagent for research purposes or as a reaction component in the synthesis of speciality chemicals. 1,5-Bis(4-hydroxyphenyl)pentane-1,5-dione has been shown to have high purity and quality.

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<p>4-Chloro-1,3-dioxolan-2-one is a reactive functional group that can be classified as a carbonyl compound. It has been shown to react with hydroxyl groups and methyl ethyl groups. 4-Chloro-1,3-dioxolan-2-one is also a strong nucleophile and can also be used in transfer reactions. <br>The reaction solution of 4-chloro-1,3-dioxolan 2 one contains constant pressure and electrochemical impedance spectroscopy (EIS). The carbonate anion reacts with hydrogen fluoride to release CO2 gas, which was observed by particle tracking velocimetry (PTV) and PTV analysis. The nitrogen atoms in the molecule are low energy and react with HCl at room temperature to produce NH4Cl. <br>4 Chloro 1,3 dioxolan 2 one is not soluble in water but it is soluble in hydrochloric</p>

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<p>Clioquinol is a topical corticosteroid that is used to treat skin disorders such as pemphigoid, psoriasis, and eczema. It is also used to treat the inflammation associated with acne. Clioquinol has been shown to be effective in treating bacterial infections of the skin by inhibiting the growth of bacteria. This drug also has anti-inflammatory properties and can be used for the treatment of various inflammatory skin conditions. Clioquinol is not absorbed through the skin and does not affect the blood's ability to clot.</p>

(+)-(1R,2R,5R)-2-Hydroxy-3-pinanone is an organic compound that can be prepared by a kinetic resolution of the racemic mixture of (+)-(1S,2S,5S)-2-hydroxy-3-pinanone. This reaction is performed in two steps: first the racemic mixture is converted to the corresponding chiral acetylacetonate by reaction with acetic anhydride followed by hydrolysis with sodium hydroxide. The pentane reacts with the ring opening of the acetylacetonate to give (+)-(1R,2R,5R)-2-hydroxypinanone and its enantiomer. The nature of this preparative method means that it is not possible to recover (+)-(1R,2R,5R)-2-hydroxypinanone from the reaction products.

1,4-Dihydroxy-2-butanone is a synthetic organic compound, often described as an intermediate or precursor in various biochemical processes. It is primarily derived from chemical synthesis methods involving the manipulation of butanone derivatives. Its chemical stability and reactivity make it a valuable compound in laboratory settings.The mode of action of 1,4-Dihydroxy-2-butanone involves its participation as a key intermediate in the biosynthesis of riboflavin, or vitamin B2, in microorganisms. Within this pathway, it undergoes several enzymatic transformations, contributing to the formation of complex structures necessary for riboflavin synthesis.The uses and applications of 1,4-Dihydroxy-2-butanone are predominantly found in research environments, where it serves as a critical component in studies focused on understanding and synthesizing riboflavin. Additionally, its role in elucidating enzyme mechanisms and exploring metabolic pathways makes it an essential compound for scientists working in the fields of biochemistry and metabolic engineering. This compound's contribution to fundamental research provides insights into potential biotechnological applications and innovations in vitamin production.

2,6-Dimethyl-2,5-heptadien-4-one is an organic compound that belongs to a class of compounds called reactive oxygen species (ROS). It is produced by the oxidation of 2,6-dimethyl-2,5-heptadienoic acid. ROS are formed in the mitochondria and have been shown to be involved in many cellular processes including mitochondrial function. ROS can induce oxidative stress leading to cell death. This compound has been shown to enhance the antibacterial efficacy of other antibiotics such as gentamycin and vancomycin. The mechanism of action is not fully understood but appears to involve intracellular glutathione depletion and damage to mitochondrial membrane potential.

<p>3-Methyl 2H-furo[2,3-c]pyran-2-one (3MHFP) is a plant hormone that belongs to the group of butenolides. It is a karrikin and has been shown to have a variety of physiological effects in plants. 3MHFP binds to specific receptors on the plasma membrane, which causes an increase in Ca++ and K+ ion flow through cell membranes. This leads to inhibition of enzymes such as dehydrocostus lactone oxidase, which are involved in the production of reactive oxygen species (ROS). 3MHFP also affects seed germination, stimulating it at low concentrations and inhibiting it at high concentrations. The mechanisms underlying these effects are not fully understood, but may be due to its ability to regulate metabolism.</p>

(2,3,4-Trimethoxyphenyl)acetone is a high quality chemical reagent that is used as a complex intermediate for the synthesis of various fine chemicals. It is also a useful scaffold and building block for the synthesis of speciality chemicals or research chemicals. (2,3,4-Trimethoxyphenyl)acetone can be used as a versatile building block in organic syntheses and has been used as a reaction component in the synthesis of substituted phenols. It is also listed on the Chemical Abstracts Service registry with CAS No. 102119-67-5.

<p>2H-1,4-Benzoxazine-2,3(4H)-dione is an organic compound that has a catalytic lactonization reaction. It has been used to form acyl groups from carboxylic acids and amides from alcohols in the presence of an acid catalyst. The cyclic lactam formed can be hydrolyzed to a linear amide by heating with water. 2H-1,4-Benzoxazine-2,3(4H)-dione is also used in the hydrogenation of nitro compounds and haloalkanes. This compound can be prepared by refluxing isatin with hydroxamic acid or solvents such as methylene chloride. This compound also undergoes hydroxamic acid reactions to form hydroxamic acids.</p>

<p>3-Thioxo-1,2,4-triazin-5-one is a chemical compound that has been shown to inhibit the growth rate of various bacteria. It inhibits the enzyme hydroxyproline hydroxylase in plants and fungi. The tautomeric form of 3-thioxo-1,2,4-triazin-5-one is found in triticum aestivum (wheat) and glyoxylate. In the presence of thiosemicarbazide or carbazone this compound undergoes a base catalyzed cyclization reaction that leads to the formation of orotic acid. 3-Thioxo-1,2,4-triazin-5-one also inhibits viral replication by blocking the synthesis of nucleobases and can be used as an antiviral agent against herpes virus.</p>

<p>Please enquire for more information about 4-(Indol-3-ylmethylene)-1,3-diphenyl-2-pyrazolin-5-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

5beta-Pregnan-3alpha,21-diol-11,20-dione (5beta-pregnan) is a fine chemical used in research and development as a building block or intermediate. It has many uses, including as a useful scaffold for complex compounds. This chemical is also an excellent reagent for the synthesis of new organic compounds. It is a versatile building block that can be used in the production of high quality speciality chemicals. 5beta-pregnan may be used to synthesize many different types of building blocks and intermediates that are useful for the synthesis of other compounds.

<p>4-Propylpyrrolidin-2-one is a chemical compound. It is the product of the condensation of two molecules of butyric acid and one molecule of hexanoic acid. The cyclization reaction occurs at the 4 position, forming a six-membered ring. This reaction can be catalyzed by bromine or UV light. Brivaracetam is a drug that belongs to the class of antiepileptic drugs and was developed as an analog of levetiracetam, which inhibits voltage-gated sodium channels in neurons. It has been shown to have only weak affinity for benzodiazepine binding sites and does not cause sedation or memory impairment.</p>

<p>5-Amino-1,3-dimethyl-1,3-dihydro-2H-benzimidazol-2-one dihydrochloride (5ADMB) is a high quality reagent that is used as a complex compound. It has been shown to be useful in the synthesis of various compounds and is a fine chemical that can be used as a building block. 5ADMB has also been shown to be an excellent scaffold for the synthesis of benzo[b]thiophenes. This compound is also useful as a research chemical or specialty chemical. 5ADMB can be used in organic syntheses as a versatile building block and it reacts with nucleophiles such as alcohols and amines to form substituted derivatives. It has an appearance of white solid powder and its CAS number is 1986846-08-5.</p>

<p>Please enquire for more information about 3-(tert-butyl)indeno[3,2-c]isoxazol-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Phosphodiesterase type 3 inhibitor; positive inotropic agent; vasodilatory</p>

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<p>2-Nitrophenylacetone is a polycyclic compound with an alkyl group, phenyl group, and a diterpenoid substituent. It is acylated with an acetate group on the 2-nitrophenyl group. The skeleton of this molecule contains a ketone (C=O) framework. The hydrogen atom in the molecule constitutes its chemistry. This molecule has been expressed in E. coli and purified to homogeneity. It constitutes the first example of a ketone containing framework for which biomolecular chemistry has been studied.</p>

2-Bromophenylacetone is a reagent that is used to synthesize sulfonamides. It can be prepared by the reaction of phenylacetic acid with bromine in the presence of sodium hydroxide. The product can then be treated with sulfuric acid and hydrochloric acid to give 2-bromophenylacetone. This compound has been shown to have bacteriostatic activity against Gram-positive bacteria, as well as being an efficient method for synthesizing thiosemicarbazide.

<p>Please enquire for more information about 3-(4-ethoxyphenyl)-5-indol-3-yl-1H,4H,5H-1,2-diazin-6-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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(2R,3S,4S,5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone is a fine chemical that is used as a versatile building block in the synthesis of complex compounds. It has been shown to be an intermediate in the synthesis of some useful chemicals and it is one of the most commonly used reagents for organic chemistry reactions. The compound has a CAS number of 115250-38-9 and is soluble in various organic solvents such as dichloromethane or chloroform.

1,2,4-Dithiazolidine-3,5-dione is a disulfide bond compound that contains a nucleophilic cysteine residue. It is oxidized to the corresponding sulfoxide or sulfone by reaction with hydrochloric acid. 1,2,4-Dithiazolidine-3,5-dione has been shown to react with amines to form adducts. The nucleophilic attack of the sulfur atom on the carbonyl carbon generates an intermediate thioketal and leaves the original disulfide intact. The nucleophilic attack leads to a number of possible products including dithioesters and dithioimidates. Both these products are stable in water and can be used in organic synthesis reactions such as DNA duplex formation.

Progesterone is a hormone that regulates the menstrual cycle and plays a key role in pregnancy. It is produced by the corpus luteum, the placenta, and the ovaries. Progesterone is also involved in regulating other functions such as cell growth, fat metabolism, blood clotting, and water balance. The level of progesterone in urine has been shown to be a good indicator of follicular growth during ovulation. In women with metabolic disorders or lactogenic hormone deficiencies, low levels of progesterone can lead to infertility.

<p>1,1,1-Trifluoro-5-hydroxy-2-pentanone is a versatile building block that has been used extensively in the synthesis of complex compounds. It is an important reagent for the preparation of speciality chemicals and reactive intermediates. 1,1,1-Trifluoro-5-hydroxy-2-pentanone is also a useful intermediate for the synthesis of other compounds. This compound can be reacted with various groups to produce valuable scaffolds for drug discovery research.</p>

The compound is a chiral molecule, meaning that it has two different structures. One side of the molecule is the mirror image of the other. The translation and conformation of this molecule are asymmetric because the carbon atoms in its chain are not lined up in a straight line. The hydrogen bonds that form between these chains are also asymmetric, as one side of the molecule has more than one hydrogen bond while the other side only has one hydrogen bond.

<p>3b,5-Dihydroxy-15b,16b-methylene-5b-androst-6-en-17-one is a steroid hormone that has been shown to have antihypertensive properties. It has been shown to reduce the production of angiotensin II by inhibiting the enzyme angiotensin converting enzyme (ACE). 3b,5-Dihydroxy-15b,16b-methylene-5b-androst-6-en 17 one has also been shown to be a potent inhibitor of the enzyme 3beta hydroxysteroid dehydrogenase type 1 (3betaHSD1) and 5alpha reductase type 2 (5alphaRD2), which are enzymes that convert cortisone to cortisol and dihydrotestosterone to testosterone respectively. These effects on steroidogenesis may account for its observed antihypertensive activity.</p>