Carboxylic Acids

<p>Phenylacetylglutamine (NSC 203800)is a normal constituent of human urine, but other mammals such as the dog, cat, rat, and horse do not excrete this compound.</p>

<p>L-Homoserine is a reactive serine variant with an extra CH2, forms a 5-membered ring, not in proteins, and is made after cyanogen bromide cleavage.</p>

<p>N-Acetyl-L-arginine dihydrate (N-Ac-L-arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic)</p>

<p>L-Cysteic acid monohydrate inhibits bacterial AspT, used in surfactants, brain studies, and as an mGluRs agonist.</p>

<p>2,3-Diaminopropanoic acid hydrochloride (3-Amino-DL-alanine monohydrochloride) is used as a substrate for studying the action of aminopeptidase enzyme.</p>

<p>3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) is a plant-derived compound first extracted from roots of Asparagus officinalis and</p>

<p>D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1</p>

<p>Acetyl-L-lysine: N-acetylated amino acid, normally found in trace urine amounts, elevated in aminoacylase I deficiency.</p>

<p>N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA (N-Methyl-D-aspartic acid) receptor subtype of glutamate</p>

<p>DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen. </p>

<p>1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene and protects against neuron cell death in vivo models of ischemia.</p>

<p>D-Galacturonic acid hydrate is used in the synthesis of N-(D-galacturonoyl) amino acids and dipeptides.</p>

<p>DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth.</p>

<p>Applications 2-Amino-2-phenylbutyric acid 96% (cas# 5438-07-3) is a useful research chemical.<br></p>

<p>Applications 3-(4-Hydroxy-3,5-dimethoxyphenyl)propanoic Acid (cas# 14897-78-0) is a useful research chemical.<br></p>

<p>Applications 2,2-dimethyl-4-oxo-4-(propan-2-yloxy)butanoic acid (cas# 1803601-41-3) is a useful research chemical.<br></p>

<p>Applications 4,4'-(ETHYNE-1,2-DIYL)DIBENZOIC ACID (cas# 16819-43-5) is a useful research chemical.<br></p>

<p>Applications 5-(3-hydroxyphenyl)pentanoic acid (cas# 31129-95-0) is a useful research chemical.<br></p>

<p>Applications Acetic propionic anhydride<br></p>

<p>Applications 4-(2-Amino-ethyl)-benzoic Acid is a useful reagent for the preparation of amino acid derivatives with anticancer activity.<br>References Kim, S., et al.: PCT Int. Appl. (2020), WO 2020204548 A1<br></p>

<p>Stability Hygroscopic<br>Applications 3-Sulfanylhexyl Acetate is a precursor of 3-mercaptohexan-1-ol (M225270) found in grape juice.<br>References Harsch, M.J., et al.: J. Agri. Food. Chem., 61, 3703 (2013); Makhotkina, O., et al.: Food. Chem., 135, 486 (2012);<br></p>

<p>Applications D-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity.<br>References He, W. et al.: Comp. Biochem. Phys. Part A: Mol. Int. Phys., 166, 308 (2013)<br></p>

<p>Applications 2-Amino-4-(methylsulfonyl)benzoic Acid is a reagent used in the synthesis of anthranilic diamides containing fluorinated groups as potential ryanodine receptors activators.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, C. et al.: Chem. Lett., 28, 1248 (2017);<br></p>

<p>Applications 2-(4-Hydroxycyclohexyl)acetic acid (cas# 99799-09-4) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxyhexanedioic Acid gets excreted in increased amounts in the human urine under conditions of medium-chain triglyceride (MCT) feeding, abnormal fatty acid oxidation (FAO) and fasting.<br>References Duran, M., et al.: Eur. J. Pediatr., 150, 190 (1991); Svendsen, J. S., et al.: J. Chromatogr. B., 337, 9 (1985); Tserng, K. Y., et al.: Metabolism, 40, 676 (1991); Tserng, K. Y., et al.: Metabolism, 445, 162 (1996)<br></p>

<p>Applications 4-(Benzyloxy)butanoic acid<br></p>

<p>Applications A metabolite of pyrethroid insecticides such as: Deltamethrin, Permethrin, Cypermethrin, Fenvalerate, Decamethrin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Woollen, B., et al.: Xenobiotica, 22, 983 (1992), Saito, K., et al.: Toxicol. Sci., 57, 54 (2000), Fang, H., et al.: Chem. Res. Toxicol., 14, 280 (2001), Andersen, H., et al.: Toxicol. Appl. Pharmacol., 179, 1 (2002),<br></p>

<p>Applications 9-Oxo-10(9H)-acridineacetic acid is a reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC and it is also a building block in pharmaceutics.<br></p>

<p>Applications Isostearic Acid may be a useful reagent in the regioselective preparation of alkenes via photoredox/cobaloxime dual-catalytic decarboxylative elimination of carboxylic acids,<br>References Cartwright, K. C., et al.: Chem. Eur. J., 26, 12454 (2020)<br></p>

<p>Applications 3,5-DINITRO-4-HYDROXYBENZOIC ACID (cas# 1019-52-9) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications Thioglycolic Acid is an organic compound containing both a thiol and a carboxylic acid. Thioglycolic Acid is a precursor to ammonium thioglycolate, a chemical used for permanents. Thioglycolic Acid is used in organic synthesis as a nucleophile in thioglycolysis reactions and is used as a S transfer agent for sulfonyl chloride synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, T.R. et al.: Bull. Kor. Chem. Soc., 3, 162 (1982); Badr, M.Z.A. et al.: Bull. Chem. Soc. Jap., 56, 326 (1983); Langler, R.F. et al.: Can. J. Chem., 57, 3193 (1979);<br></p>

<p>Applications Ethyl Cyano(hydroxyimino)acetate is used in peptide synthesis and has shown to suppress racemiztion, has high coupling efficiency in both solution and solid phase synthesis and is a non-explosive alternative to 1-hydroxybenzotriazole (HOBt) and 1-hydroxy-7-azabenzotriazole (HOAt).<br>References Khattab, S.N.: Bull. Chem. Soc. Jpn., 83, 1374 (2010)<br></p>

<p>Applications 4-(4,6-Bis(4-((2-ethylhexyloxy)carbonyl)phenylamino)-1,3,5-triazin-2-ylamino)benzoic Acid is an impurity in the synthesis of Ethylhexyl Triazone (E918810), used in sunscreen formulations as a UV filter to block out harmful ultraviolet light.<br>References Potard, G. et al.: Int. J. Pharm., 189, 249 (1999); Couteau, C. et al.: J. Pharm. Biomed. Anal., 44, 270 (2007);<br></p>

<p>Applications Formamidine Sulfuric Acid is a reagent used in reduction and synthesis reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ma, Q. et al.: Carbon, 54, 36 (2013);<br></p>

<p>Applications 2-aminobenzene-1,4-disulfonic acid (cas# 98-44-2) is a useful research chemical.<br></p>

<p>Applications Methyl (S)-N-Tritylaziridine-2-carboxylate (cas# 75154-68-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Ethylbutyric Acid is used in biological studies as a possible descriptor for toxicity prediction through electrophilicity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roy, D.R., et al.: Bioorg. Med. Chem., 13, 3405 (2005); Parthasarathi, R., et al.: J. Phys. Chem. A., 107, 10346 (2003)<br></p>

<p>Applications Isotope labelled 1,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid is a widely used and often incorporated in plasticizer for PVC for a higher molecular weight.<br>References Jones, C., et al.: Int. J. Artificial. Organs., 12, 466 (1989); Khang, G., et al.: Bio-Med. Mater. Engineer., 12, 135 (2002);<br></p>

<p>Applications 1,3-Adamantanedicarboxylic acid, is a monomer that can be used in polymer science, self assembly and lithography.<br></p>

<p>Stability Volatile<br>Applications Methyl Acetate is used as an organic chemical solvent for a multitude of organic processes. Also used in the production of biodiesel.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, Y. et al.: J. mol. Cat., 32, 241 (2005); Ogino, H. et al.: J. Biosci. Bioeng., 89, 451 (2000);<br></p>

<p>Applications 2-(carboxymethyldisulfanyl)acetic acid (cas# 505-73-7) is a useful research chemical.<br></p>

<p>Applications 2-Hydroxybutanoic Acid is an analyte used in the diagnoses of colorectal cancer as well as Type II diabetes. It is also used in the purification of the major Vibrio autoinducer and the study of its role in virulence factor production for cholera.<br>References Qiu, Y. et al.: J. Proteome Res., 8, 4844 (2009); Salek, R.. et al.: Phys. Genom., 29, 99, (2007); Higgins, D. et al.: Nature, 450, 883 (2007);<br></p>

<p>Applications (E)-Cyano(methoxyimino)-acetic Acid is a degradation product of Cymoxanil (C988995), which is a fungicide applied as a seed treatment or as a foliar application to the plants to control late blight.<br>References Morrica, P., et al.: J. Agric. Food Chem. 52, 99 (2004); Dhingani, J. C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Bakirici, G.T., et al.: Food. Chem., 135, 1901 (2012)<br></p>

<p>Stability Moisture Sensitive<br>Applications Phosphoric Acid Tributyl Ester is used as a solvent in the solvent-detergent method for production of immunoglobulin for inactivation of viruses with lipid envelope on the model of duck hepatitis B virus. It is also used as a ligand in the extraction of lanthanide ions from solid and liquid materials by supercritical CO2.This compound is a contaminant of emerging concern (CECs).<br>References Zubkova, N., et al.: Bull. Exp. Biol. Med., 155, 821 (2013); Lin, Y., et al.: Anal. Chem., 66, 1971(1994)<br></p>

<p>Applications Glyoxylic Acid is used as a reagent in the synthesis of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine, a novel nonpeptide chemotype selective for neurotensin receptor 2. Also used as a reagent in the synthesis of elemonic acid derivatives as Pin1 inhibitors.<br>References Thomas, J.B., et al.: Bioorg. Med. Chem. Lett., 25, 292 (2015); Li, X., et al.: Bioorg. Med. Chem. Lett., 24, 5612 (2014)<br></p>

<p>Applications 3-Oxohexanedioic Acid is a degradation product of catechol in the presence of hydrogen peroxide; Also, it is derived from 3-Oxohexanedioic Acid Diethyl Ester (O856830), which is an intermediate used to prepare CMPF (C595000) which is a drug-binding inhibitor which is also a constituent of urine. CMPF can inhibit specific T4 binding in serum by increasing the free concentration of direct competitors.<br>References Gogoi, A., et al.: Chem. Eng. J., 311, 153-162 (2017); Mabuchi, H., Nakahashi, H.: Nephron, 44, 277 (1986); Lim, C.F., et. al.: Metabolism Clin. Exp., 42, 1468 (1993)<br></p>

<p>Applications Fendizoic Acid is a reagent in the synthesis of fluorinated polyphthalazinone ethers containing perfluorophenylene moieties.<br>References Lu, Z., et al.: J. Polym. Sci. A1, 42, 925 (2004)<br></p>

<p>Applications Phosphoric acid, ammonium salt (1:1) is a useful reagent for organic synthesis.<br></p>

<p>Applications 7-Bromoheptanoic Acid is a reagent that is used in the synthesis of N-Heptanoic Acid Tianeptine Disodium Salt (H281500) which are metabolite of Tianeptine (T436800), having psychostimulant, anti-ulcer and anti-emetic properties.<br>References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),<br></p>

<p>Applications Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate (cas# 144172-24-7) is a useful research chemical. It is an intermediate in the synthesis of IN-KG 433 (I627995). IN-KG 433 is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>

<p>Applications 2-(7-Amino-2-oxo-2H-chromen-4-yl)acetic acid (cas# 85157-21-7) is a useful research chemical.<br></p>

<p>Applications Crotonic Acid is found in water extracts from carrot seeds (Daucus carota L.) and is shown to have strong herbicidal properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jasicka-Misiak, I., et al.: Phytochemistry, 66, 1485 (2005)<br></p>

<p>Applications Trimellic Acid is a reagent used in the preparation of coordination polymers containing various luminescent properties.<br>References Zhang, Z. et al.: Crys. Grow. Des., 13, 4338 (2013); Qin, L. et al.: Trans. Met. Chem., 38, 627 (2013);<br></p>

<p>Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.<br></p>

<p>Applications 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid is a reagent used in the preparation of hapten and immunogen for the production of polyclonal antibodies, specific to Cypermethrin (C989000).<br>References Lee, N. et al.: J. Agri. Food Chem., 46, 520 (1998); Hongsibsong, S. et al.: Int. J. Agri. Biol., 14, 246 (2012);<br></p>

<p>Applications DL-CITRAMALIC ACID (cas# 2306-22-1) is a useful research chemical.<br></p>

<p>Applications Benzensulfonic Acid Monohydrate is used in the synthesis of HER2/EFGR dual inhibitors in the treatment of cancers and displaying potency towards anti-tumor activity.<br>References Kawakita, Y. et al.: Bioorg. Med. Chem. Lett., 20, 6171 (2012);<br></p>

<p>Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxyphenylacetic Acid (cas# 621-37-4) is a compound useful in organic synthesis.<br></p>

<p>Applications DL-2-aminobutyric acid<br></p>

<p>Applications Levulinic Acid is derived from the degredation of cellulose and is a potential precursor to biofuels. Levulinic acid is also a photosensitizer for photodynamic therapy.<br>References Serrano-Ruiz, J.C., et al.: Catalysis., 195, 162 (2012); Liedtke, A.J. et al.: Tetrahedron., 68, 10049 (2012);<br></p>

<p>Impurity Methyl Salicylate USP Related Compound A<br>Applications 4-Hydroxy-isophthalic Acid Dimethyl Ester (cas# 5985-24-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-hydroxy-2-nitrobenzoic acid (cas# 74230-08-3) is a useful research chemical.<br></p>

<p>Applications Bis(2,4,4-trimethylpentyl)phosphinic acid (cas# 83411-71-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Isopropyl Acetate is a widely used chemical solvent in organic and industrial syntheses. Also used in the dissolution of gallstones.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zakko, S. et al.: Gastroenterol., 113, 232 (1997); Loeser, E. et al.: J. Chromatogr. A., 1216, 3409 (2009);<br></p>

<p>Applications Bromochloroacetic acid is a halogenated disinfection byproduct commonly found in drinking water, fruit juice, and cheese. Bromochloroacetic acid has been shown to cause mesothelioma, fibroadenomas, and adenomas in rats<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hang, C., et al.: Sci Total Environ. 543, 425 (2016); Cardador, M. J. and Gallego, M.: Food Chem. 173, 685 (2015); Natl Toxicol Program Tech Rep Ser. 549, 1 (2009)<br></p>

<p>Impurity Sertraline EP Impurity E<br>Applications (R)-(-)-Mandelic Acid (Sertraline EP Impurity E) is an antiseptic (urinary).<br>References Pessela, B., et al.: Enzyme Microb. Technol., 40, 310 (2007), Carrasco-Lopez, C., et al.: J. Biol. Chem., 284, 4365 (2009),<br></p>

<p>Applications An intermediate of Montelukast.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1,1-Cyclohexanediacetic acid monoamide is an impurity of Gabapentin (G117250), an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Gabapentin is used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>

<p>Applications 2-Mercaptoisobutyric Acid, 90% (cas# 4695-31-2) is a compound useful in organic synthesis.<br>References McIntosh, J.M. and Siddiqui, M.A.: Can. J. Chem., 61, 1872-1875 (1983), Bienlarz, C. and Cornwall, M.J.: Tetrahedron Lett., 34 (6), 939-942 (1993)<br></p>

<p>Applications Butyl Acetate, can be used as a synthetic fruit flavoring in foods such as candy, ice cream, cheeses, and baked goods.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ullman's encyclopedia of industrial chemistry, 6th Ed., 1, 170 (2003);<br></p>

<p>Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.<br>References Kono, K. et al.: J. Antibiot., 53, 759 (2000);<br></p>

<p>Applications (R)-2-Hydroxybutanoic acid (cas# 20016-85-7) is a useful research chemical.<br></p>

<p>Applications Phthalanilic acid is a compound that is useful in the production of fertilizers.<br>References Liang, S., et al.: Faming Zhuanli Shenqing.,4 (2019)<br></p>

<p>Applications Parabanic acid appears to be an important marker of free radical reactions in vivo and may be used to monitor free radical activity and to evaluate pharmacological therapy with radical scavengers.<br>References Koumoto, Y., et al.: J. Biol. Chem., 276, 29688 (2001), Gibon, Y., et al.: Plant Cell, 16, 3304 (2004), Kaplan, F., et al.: Plant J., 44, 730 (2005), Ishii, N., et al.: Science, 316, 593 (2007),<br></p>

<p>Applications (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl Acetate is an intermediate in the synthesis of JHSB3 (J211030). JHSB3 is an acyclic sesquiterpenoid that regulates many aspects of insect physiology. Juvenile Hormone regulate development, reproduction, diapause, and polyphenisms.<br>References Kotaki, T., et al.: Org. Let., 11, 5234 (2009); Riddiford, L.: Adv. Insect Physiol., 24, 213 (1994); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, 1 (1996); Nijhout, H.: Insect Hormones (Princeton Univ. Press, Princeton) (1994)<br></p>

<p>Applications Isotope labelled Trifluoroacetic Acid used as a solvent in a variety of organic synthesis and chemical processes. Used in the synthesis of anticancer agents as well as phospholipase D inhibitors.<br> E0<br>References Scott, S. et al.: Nat. Chem. Biol., 5, 108 (2009); Minko, T. et al.: Cancer. Chemother. Pharmacol., 50, 143 (2002);<br></p>

<p>Applications Sebacic Acid is a urinary metabolite that has been identified as an anti-fatigue biomarker.<br>References Ma, C. et. al.: J. Pharmaceut. Biomed. Anal. 105, 84 (2015)<br></p>

<p>Applications (S)-2-Amino-4-[(3-aminopropyl)amino]-butanoic Acid is used in the reaction of carboxynorspermidine decarboxylase of Vibrio alginolyticus.<br>References Nakao, H., et al.: J. Gen. Microbiol. 136, 1699-704 (1990)<br></p>

<p>Applications A redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide. A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gough, J.D., et al.: JACS, 124 (15), 3885 (2002)<br></p>

<p>Applications Octyl 3-Octyloxiraneoctanoic Acid (cas# 106-84-3) is a compound useful in organic synthesis.<br></p>

<p>Applications (2E)-3-Phenyl-2-propenoic Acid is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines. Also used in the N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>

<p>Applications ethyl 2-cyclopropyl-2-hydroxyacetate (cas# 1185387-66-9) is a useful research chemical.<br></p>

<p>Applications 1-Dodecanol Acetate can be used as a foaming agent in the purification process of quartz sand. Furthermore, it is a main component of the essential oil from the flowers of Etlingera elatior (Jack) R. M. Smith, which is found to be active against Staphylococcus aureus, Bacillus cereus, Candida albicans and Cryptococcus neoformans.<br>References Wang, W., et al.: Faming Zhuanli Shenqing, CN 103663469 A 20140326 (2014); Susanti, D., et al.: Journal of Essential Oil-Bearing Plants, 16, 294 (2013)<br></p>

<p>Applications Used in the synthesis of substituted terphenyls.<br>References Strukelj, M., et al.: Science, 267, 1969 (1995), Burroughes, J., et al.: Nature, 347, 589 (1990),<br></p>

<p>Applications 2,2,5-Trimethyl-1,3-dioxane-5-carboxylic Acid (cas# 16837-14-2) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications Eye irritant.<br>References Bagley, D. M. et al.; Toxicol. In Vitro 13, 505 (1999); Gilleron, L. et al.; Toxicol. In Vitro 11, 641 (1997)<br></p>

<p>Applications N-[4-(-Carboxycyclohexylmethyl)]maleamidic Acid (cas# 72748-87-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Reagent used to prepare Guanidine derivatives.<br>References Nozawa, D., et al.: Bioorg. Med. Chem. Lett., 11, 1481 (2001), Choudhury, A., et al.: Biochem., 46, 4066 (2007), Yuan, D., et al.: Bioorg. Med. Chem., 15, 265 (2007),<br></p>

<p>Applications Empagliflozin Tetraacetate is an Empagliflozin (E521510) impurity and is a reagent used to design and synthesize nitric oxide releasing derivatives of dapagliflozin which has potential antidiabetic and antithrombotic agents.<br>References Zheng, L., et al.: Bioorg. Med. Chem., 26, 3947 (2018)<br></p>