Carboxylic Acids

<p>Please enquire for more information about 2-(4-Tolylamino-3,5-thiazolyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(N-(2-(3,4-dimethoxyphenyl)ethyl)carbamoyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((4-(2-Fluorophenyl)piperazinyl)carbonyl)cyclohexanecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(Benzylamino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-((2-bromophenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((3-(Trifluoromethoxy)phenyl)amino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-((5,5-Dimethyl-3-oxocyclohex-1-enyl)amino)benzoic acid (DMACBA) is a channel inhibitor that blocks the voltage-gated sodium channels in neurons. It has been shown to be effective against malignant brain tumors. DMACBA inhibits the conformational changes of the channel caused by glycols and microwave irradiation. It also stabilizes the open state of the channel, preventing it from closing again after being opened by an action potential. This agent is stable in water and forms dimers with benzoic acid. DMACBA binds to pyrimidine in DNA, inhibiting bacterial replication and transcription.</p>

<p>Please enquire for more information about 3-((2-Nitrilo-4,4-dimethyl-3-oxopent-1-enyl)amino)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-((3,5-bis(Trifluoromethyl)phenyl)amino)-3,5-thiazolyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-((3-(trifluoromethyl)phenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5,5-dimethyl-2-(3-phenoxyphenyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about methyl 2-((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)carbonylamino)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cholesterol Phenylacetate is a fatty acid that has been shown to inhibit the synthesis of phosphatidylethanolamine, an important component in cell membranes. This leads to a decrease in the rate of malignant tumor growth and death protein production. Cholesterol Phenylacetate also inhibits the expression of pro-inflammatory genes, which may be due to its ability to inhibit fatty acid synthesis. This compound is effective in reducing atherosclerotic lesions and hyperproliferative diseases, such as cancer.</p>

<p>Please enquire for more information about 2-(2-(N-(4-(Trifluoromethoxy)phenyl)carbamoyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((2,5-dichlorophenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(Prop-2-enylamino)-5-methyl-2,4-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2,4-Dibromophenoxy)acetic acid is a chemical compound with an empirical formula of C7H4Br2O4. The crystalline form of this compound has been analysed and optimised for surface analysis and crystallography. This molecule is also a model compound for coordination chemistry studies. Experimental data has been collected from bioassays that demonstrate the ligand's ability to bind to metal ions. X-ray crystallography has shown the molecular structure of (2,4-dibromophenoxy)acetic acid as a ligand in coordination with a metal ion in which the bromine atom is bonded to two oxygen atoms on the metal ion, forming a trigonal bipyramidal geometry.</p>

<p>Please enquire for more information about 4-(2,6,6-Trimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-oxo-7-(benzyloxy)hydroquinoline-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4,5-Dimethoxy-2-(thiomorpholin-4-ylsulfonyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(3,4-Dimethoxyphenyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((3,4-dimethoxyphenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-[(4-Nitrophenyl)thio]benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-(3-pyridylamino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Camphorquinone-10-sulfonic acid hydrate is a soybean trypsin inhibitor that is used as a preparative agent in organic synthesis. It reacts with histidine, lysine residues, and other molecules to form a light-chain kinase that inhibits the action of the enzyme trypsin. Camphorquinone-10-sulfonic acid hydrate has been shown to be resistant to proteolysis by gastrointestinal enzymes. This agent also has diabetogenic properties by inhibiting the activity of membrane potential and chloride channels in pancreatic β cells. Camphorquinone-10-sulfonic acid hydrate forms an ion pair with choline, which can inhibit the enzyme acetylcholinesterase, leading to accumulation of acetylcholine at nerve endings.</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(((4-(trifluoromethyl)phenyl)amino)sulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid (3CFP) is a phenoxy carboxamide that is an anticonvulsant. 3CFP has been shown to be effective in animal models of seizure and has a potency that exceeds that of phenobarbital. It also has potent anticonvulsant activity against seizures induced by pentylenetetrazole and electroshock. 3CFP binds to the GABA receptor, which is important for the regulation of neuronal excitability and is the target for many types of antiepileptic drugs. The chlorine atom in 3CFP may contribute to its pharmacological properties because it can form a covalent bond with amino acids like cysteine, which are important for protein synthesis.</p>

<p>Please enquire for more information about 3-(N-(4-(Dimethylamino)phenyl)carbamoyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-(N-(3-Nitrophenyl)carbamoyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((4-fluorophenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ethyl 2-(4-(4-fluorophenylamino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(4-Bromophenyl)-2-indol-3-yl-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(morpholin-4-ylsulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-(benzylamino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(2-(4-Bromophenyl)-6,6-dimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-(N-(4-(Isopropyl)phenyl)carbamoyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-(3,5-Dichlorophenylamino)-3,5-thiazolyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4,5-Dimethoxy-2-(((4-methoxyphenyl)amino)sulfonyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5,5-Dimethyl-2-(3-pyridyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-((4-(trifluoromethoxy)phenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Phenylamino-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(N-prop-2-ynylcarbamoyl)prop-2-enoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((4-Bromophenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-((3,5-bis(trifluoromethyl)phenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications 2-(bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid (cas# 171557-31-6) is a useful research chemical.<br></p>

<p>Applications cis-10-Pentadecenoic Acid is a monounsaturated fatty acid, that can inhibits IFN-γ-induced production of kynurenine in Thp-1 cells by 16%.<br>References Costabile M. et al.: Prostaglandins Leukot. Essent. Fatty Acids 122, 7-15 (2017).;<br></p>

<p>Applications 2-Isopropoxy-2-phenylacetic acid<br></p>

<p>Applications 4-​(Dimethyloxidoamino)​butanoic Acid Hydrochloride, is a metabolite of Lauramine Oxide (L178530), which is a frequently used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases.<br>References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006); Turan, T.S., et al.: Xenobiotica, 11, 447 (1981)<br></p>

<p>Stability Light, Temperature and Moisture sensitive<br>Applications trans-N-(1E)-1,3-Butadien-1-yl-carbamic Acid 2,2,2-Trichloroethyl Ester (cas# 77627-82-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl Oxirane-2-carboxylate is an intermediate used in the synthesis of DL-Indole-3-lactic Acid-d5 (I627102), which is the isotope labelled analog of DL-Indole-3-lactic Acid (I627100); a reagent in the synthesis of 2-hydroxy-1-(1H-indol-3-yl)-4-methylpentan-3-one which has weak antibacterial activity against 16 bacterial strains, including Escherichia coli, Bacillus subtilis and Staphylococcus aureus. DL-Indole-3-lactic Acid is also used in the preparation of Monatin, a natural sweet peptidomimetic.<br>References Nguyen, S.T., et al.: Bioorg. Med. Chem. Lett., 20, 5739 (2010); Nakamura, K., et al.: Peptide Sci., 40, 61 (2003)<br></p>

<p>Applications 3-Oxohexanedioic Acid Diethyl Ester is an intermediate used to prepare CMPF (C595000) which is a drug-binding inhibitor which is also a constituent of urine. CMPF can inhibit specific T4 binding in serum by increasing the free concentration of direct competitors.<br>References Mabuchi, H., Nakahashi, H.: Nephron, 44, 277 (1986); Lim, C.F., et. al.: Metabolism Clin. Exp., 42, 1468 (1993)<br></p>

<p>Applications Benzenecarbothioic Acid is used in the preparation of anti-leishmanial activity. Also used in the preparation of agents for the treatment against Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andrews, P. et al.: Aus. J. Chem., 66, 1297 (2013); Linning, P. et al.: Org. Biomol. Chem., 10, 8216 (2012);<br></p>

<p>Applications 4-Hydroxy-3-nitrobenzoic acid<br></p>

<p>Applications 4,4'-Dithiobisbenzoic Acid Dimethyl Ester (cas# 35190-68-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 4-Chloroacetoacetate (cas# 638-07-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl 3-(bromomethyl)cyclobutanecarboxylate (cas# 89892-95-5) is a useful research chemical.<br></p>

<p>Applications 2-CYCLOPENTYL-2-PHENYLACETIC ACID (cas# 3900-93-4) is a useful research chemical.<br></p>

<p>Applications 2,4,5-TRIMETHOXYBENZOIC ACID (cas# 490-64-2) is a useful research chemical.<br></p>

<p>Applications An intermediate of Rosuvastatin.<br></p>

<p>Stability Very Very Moisture sensitive<br>Applications Chloroformic Acid Chloromethyl Ester is used as a reagent in the synthesis of carbamates and carbonates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Safadi, M. et al.: Pharm. Res. 10, 1350 (1993); Loren, J.C. et al.: Synlett, 18, 2847 (2005);<br></p>

<p>Applications methyl 2,4-dichlorothiazole-5-carboxylate (cas# 861708-66-9) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications Vinylacetic Acid can be used as a reagent in the synthesis of 4-Phenyl-3-butenoic Acid which is an in vivo inhibitor of the peptide amidating enzyme peptidylglycine hydroxylase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bradbury, A.F., et al.: Eur. J. Biochem., 189, 33 (1990)<br></p>

<p>Applications Bis[2-​(1-​methylethyl)​phenyl] Ester Phosphorochloridic Acid is an intermediate in the synthesis of Bis(2-isopropylphenyl) Phenyl Phosphate (B451445), which is a triaryl phosphate used as plasticizers in polyvinyl chloride (PVC) as well as a flame retardant. Studies show that Bis(2-isopropylphenyl) Phenyl Phosphate inhibits the human androgen receptor.<br>References Duke, A.J.: Chimia, 32, 457 (1978); Honkakoski, P. et al.: Biochem. Pharmacol., 67, 97 (2004); Nobile, E.R. et al.: Bull. Environ. Contam. Toxicol., 25, 755 (1980);<br></p>

<p>Applications 5-Ethyl-2-fluorophenylboronic acid<br></p>

<p>Applications Hexahydro-4-oxo-1(2H)-azocinecarboxylic Acid 1,1-Dimethylethyl Ester is a chemical reagent used in organic synthesis.<br></p>

<p>Applications 3-(3-Furyl)acrylic Acid is a reactant in the preparation of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1.<br>References Hornberger, K.R., et. al.: Bioorg. Med. Chem. Lett., 23, 4517 (2013)<br></p>

<p>Applications Methyl Dimethoxyacetate is used as a reagent in the synthesis of benzimidazole derivatives for use as respiratory syncytial virus inhibitors.<br>References Cooymans, Ludwig Paul; D., et al. PCT Int. Appl. WO 2012080446 A1 20120621. Jun 21, 2012<br></p>

<p>Applications Methyl Isocyanoacetate, is used in the Cu-catalyzed, diastereoselective synthesis of oxazolines (O846550).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ideguchi, T., et al.: J. American Chem. Soc., 135, 12568 (2013);<br></p>

<p>Applications 5-(aminomethyl)-2-furoic acid hydrochloride (cas# 934-65-6) is a useful research chemical.<br></p>

<p>Applications 2-Ethoxy-4-ethoxysulfonylbenzoic Acid is a derivative of Methyl 2-Ethoxybenzoate (M220113), a useful chemical reagent, used in the synthesis and antibacterial triazoles and oxadiazoles, as well as sulfonamide compounds.<br>References Shi, Z. et al.: Compt. Rend. Chim., 18, 1320 (2015);<br></p>

<p>Applications 1-Hydroxycyclopentanecarboxylic Acid is a reagent used in the preparation of pyridone-conjugated monobactam antibiotics showing gram-negative activity.<br>References Brown, M. et al.: J. Med. Chem., 56, 5541 (2013); Rozhko, E. et al.: ChemCatChem., 5, 1998 (2013);<br></p>

<p>Applications 2,4-Xylenesulfonic Acid, is used for the preparation of 2,4,5,6-Tetrachloro-m-xylene (T291555). It is also an intermediate for the synthesis of Diphenylbismuth arenesulfonates.<br>References Sharutin, V. V., et al.: Russian J. Gen. Chem., 70, 687 (2000);<br></p>

<p>Applications 5-Aminononane-5-carboxylic Acid is a reagent used in the synthesis of Fmoc-α-​dialkylamino acids.<br>References Suresh B. et al.: Indian J. Chem. Section B: Chem. Inc. Med., 40B, 70 (2001);<br></p>

<p>Applications Dimethyl-1,3-acetonedicarboxylate is used in the preparation of optically active lycorane. It has also been substituted into bispidone derivatives for their use as ligands in PET imaging.<br>References Yoshizaki, H. et al.: J. Org. Chem., 60, 2016 (1995); Legdali, T. et al.: J. Org. Chem., 77, 11167 (2012);<br></p>

<p>Applications Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>