Carboxylic Acids

Applications Cyclopentylacetic acid is a reagent the synthesis of Cyclopentamine (C988355), which is a vasoconstrictor that acts as a releasing agent of the neurotransmitters norepinephrine, epinephrine and dopamine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schmidt, J.L. et al.: J. Pharmacol. Exp. Ther., 145, 83 (1964); Iversen, L.L.: J. Pharm. Pharmacol., 16, 435 (1964);

Applications 4-(Benzyloxy)butanoic acid

Applications 2-Ethylheptanoic Acid is used in the preparation of prostaglandin which is for for promoting bone growth
References Barrett, S., et al.: PCT Int. Appl., 331 (2015)

Applications N,N'-Bis(2,6-diisopropylphenyl)-1,6,7,12-tetraphenoxy-3,4,9,10-perylenetetracarboxylic Diimide has applications in the photosensors and optical detectors.
References Wang, Shaojun, et al.: ACS Photonics, 5(6), 2478-2485 (2018);Wang, Hanlin, et al.: Adv. Mat., 29(32), n/a. (2017)

Applications 4-Hydroxy-3,5-dimethylbenzoic Acid is used in the synthesis of Mexiletine (M340800) derivatives as orally bioavailable inhibitors. Also, used as a chemical reagent in the preparation of potent transthyretin (TTR) amyloidogenesis inhibitors affecting thyroid hormone.
References Frederickson, M. et al.: J. Med. Chem., 51, 183 (2008); Johnson, S. et al.: J. Med. Chem., 51, 260 (2008);

Applications A reagent used in the synthesis of glycidol, a stabilizer in manufacturing of vinyl polymers; intermediate in synthesis of glycerol, glycidyl ethers, and amines; additive for oil and synthetic hydraulic fluids; epoxy resin diluent.
References Palomo, J.M. et al.: Tetrahedron Asymm., 16, 869 (2005); Hiles, R.A., et al.: Food Cosmet. Toxicol., 19, 347 (1981); Thompson, E.D., et al.: Food Chem. Toxicol., 22, 665 (1984);

Applications 1,2,3,4-Cyclobutanetetracarboxylic Acid is a reagent used in the preparation of cobalt cyclobutanetetracarboxylate polymer.
References Diaz-Gallifa, P., et al.: Inorg.Chem., 53, 5674 (2014)

Applications Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester is used in the discovery of a potent, selective and orally bioavailable dual CCR2 and CCR5 antagonist.
References Zheng, C., et al.: Bioorg. Med. Chem. Lett., 21, 1442-1446 (2011)

Applications 4-Ethylsulfonylphenylboronic acid is used in the discovery of small molecular RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis.
References Harris, P. A,, et al.: ACS Med. Chem. Lett., 4, 1238 (2013)

Applications 1-Butenylboronic Acid is a reagent used in the synthesis of polyene natural products.
References Lee, S. J., et al.: J. Am. Chem. Soc., 130, 466-468 (2008)

Applications 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid is a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.
References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)

Applications 6-cyano-2-oxaspiro[3.3]heptane-6-carboxylic acid (cas# 1934971-05-7) is a useful research chemical.

Applications 1,2,4-Benzenetricarboxylic acid 1,2-Dihexyl Ester is a useful reagent for organic synthesis.

Applications 4'-Hydroxybiphenyl-3-carboxylic Acid is a biaryl compound that can be prepared via palladium bis[(dipiperidinylphosphino)amino]phenyl-catalyzed Suzuki-Miyaura cross coupling reactions of organoboronic acids or trifluoroborates and aryl bromides and can also be synthesized by simultaneous hydroxylation and carboxylation of biphenyls. 4'-Hydroxybiphenyl-3-carboxylic Acid is a useful building block with applications in various syntheses.
References Shibahara, F., et al.: Org. Lett., 6, 2437 (2004); Bolliger, J., Frech, C.: Adv. Synth. Catal., 352, 1075 (2010);

Applications 1,2,4,5-BENZENETETRACARBOXYLIC ACID (cas# 89-05-4) is a useful research chemical.

Stability Moisture Sensitive
Applications 5,5-Dibromobarbituric Acid (cas# 511-67-1) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Dibromoacetic Acid is a halogenated disinfection byproduct. Dibromoacetic Acid was found to induce apoptotic changes and hydroxyl radical formation in human peripheral blood mononuclear cells (PBMCs). Dibromoacetic Acid also found to exhibit carcinogenic activity in which mice and rats were exposed to drinking water containing different concentrations of Dibromoacetic Acid that resulted in increased incidences of mononuclear cell leukemia, malignant mesothelioma, hepatocellular neoplasms, and hepatoblastoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Michalowicz, J., et al.: Toxicol. In Vitro 29, 1416 (2015); Natl Toxicol Program Tech Rep Ser. 537, 1 (2007)

Applications 3-Amino-4-(carboxymethyl)benzoic acid

Applications tert-Butyl 3-Cyanomorpholine-4-carboxylate is used as a reactant for the synthesis of HIV integrase inhibitors.
References Gardelli, C., et. al.: J. Med. Chem., 50, 4953 (2007); Pace, P., et. al.: J. Med. Chem., 50, 2225 (2007); Summa, V., et. al.: J. Med. Chem., 49, 6646 (2006)

Applications 3-(9H-carbazol-9-yl)propanoic acid (cas# 6622-54-4) is a useful research chemical.

Applications An intermediate of Rosuvastatin.

Applications 4,4'-Dithiobisbenzoic Acid Dimethyl Ester (cas# 35190-68-2) is a compound useful in organic synthesis.

Applications 9-Ethyl-9H-carbazole-3-carboxylic Acid is a useful reagent for the preparation of an oxime ester photoinitiator.
References Hu, C., & Yu, P.: Faming Zhuanli Shenqing (2020), CN 111320714 A

Applications Dihydroxyfumaric Acid Dimethyl Ester is used in the reactions involving of β-sheet formation.
References Kemp, D. et al.: J. Org. Chem., 55, 4650 (1990);

Applications 3,4-Bis(phenylmethoxy)-benzoic Acid is a useful synthetic intermediate. It is an intermediate used to synthesize Jaboticabin (J210370) which is minor bioactive depside potent to treat chronic obstructive pulmonary disease.
References Wu, S., et al.: J. Agri. Food Chem., 61, 4035 (2013); Reynertson, K., et al.: J. Nat. Prod., 69, 1228 (2006)

Applications 5-Ethyl-2-fluorophenylboronic acid

Applications Ethyl 2-Isopropylacetoacetate is a reactant in the preparation of nonracemic arylhydroxymethylpyrrolidinylmethylphenyl thiazoleacetamides and cyclopentathiazolecarboxamides as conformationally restricted β3-adrenoceptor agonists as a potential treatment for overactive bladder.
References Moyes, C.R., et. al.: J. Med. Chem., 57, 1437 (2014)

Applications 5-Aminononane-5-carboxylic Acid is a reagent used in the synthesis of Fmoc-α-​dialkylamino acids.
References Suresh B. et al.: Indian J. Chem. Section B: Chem. Inc. Med., 40B, 70 (2001);

Applications 2-(Aminosulfonyl)benzoic Acid can be used as reactant/reagent in synthesis and pharmacological activity of γ-(phenyloxamido)- and γ-(phenylsulfonyloxamido)butanoic acids.
References Georgiyants, V. A., et al.: Farmatsevtichnii Zhurnal, 2, 34 (2010);

Applications Methyl 5-chlorothiophene-2-carboxylate (cas# 35475-03-7) is a useful research chemical.