Carboxylic Acids

Applications 3-(3-THIENYL)ACRYLIC ACID (cas# 102696-71-9) is a useful research chemical.

Applications (6,7-dimethoxy-4-oxoquinazolin-3(4H)-yl)acetic acid (cas# 877140-09-5) is a useful research chemical.

Applications 2-(Diphenylphosphoryl)acetic acid (cas# 1831-63-6) is a useful research chemical.

Applications 2,5-Dimethylthiophene-3-boronic acid

Applications 2-(chroman-4-yl)acetic acid (cas# 5655-26-5) is a useful research chemical.

Applications Methyl (3α,5β,6α)-3-(Acetyloxy)-6-bromo-7-oxo-cholan-24-oic Acid Ester is an intermediate used in the synthesis of ω-Muricholic Acid (M732760), which is used in the regulation of weight gain and lipid metabolism by bacterial bile acid modification in gut for the control of obesity and hypercholesterolemia.
References Joyce, Susan A., et al.: Proc. Natl. Acad. Sci. USA, 111, 7421 (2014)

Stability Hygroscopic
Applications 2,​2-​Bis(hydroxymethyl)​propionic Acid is a reagent used in the synthesis of disulfide monomers for cross-linked poly(urethane-urea) coatings.
References Nevejans, S. et al.: Polym., 166, 229 (2019);

Applications S-Acetylthioacetic Acid (cas# 1190-93-8) is a compound useful in organic synthesis.
References Fox, M., et al.: J. Microbiol. Methods, 56, 221 (2004),

Applications Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutylpiperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy.
References Chezal, J.M., et al.: J. Medn. Chem., 51, 3133 (2008); Heinrich, T., et al.: J. Medn. Chem., 47, 4684 (2004);

Applications 4-Amino-1,3-benzenedisulfonic Acid is used as a reagent in the synthesis of arylazopyridoxal phosphate and phosphonate derivatives as P2 receptor antagonists.
References Kim, Y., et al.: Drug Develop. Res., 45, 52 (1998)

Applications Ethyl 4,4-Difluoroacetoacetate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.
References Qi, J.L., et al.: Euro. J. Medn. Chem., 46, 934 (2011); Schirlin, D., et al.: J. Enzymes. Inhibition., 1, 243 (1987);

Stability Moisture Sensitive, Air Sensitive
Applications As-Methyl Arsonothioic Acid is used as a standard for arsenic inspection. It is used as an aid to help in determining the level of toxicity in humans. Metabolite in some mammals and microbiota.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Naranmandura, H. et al.: Chem. Res. Toxicol., 24, 1586 (2011); Bu, N. et al.: Metallom., 3, 1064 (2011);

Applications (1-acetyl-2,3-dihydro-1H-indol-5-yl)boronic acid (cas# 905971-97-3) is a useful research chemical.

Applications 5-Formylfuran-2-boronic Acid Neopentyl Glycol Ester is a useful reagent in lapatinib synthesis.
References Radl, S., et al.: PCT Int. Appl. (2014), WO 2014059956 A1

Applications Methyl 5-Chloro-3-(Chlorosulfonyl)Thiophene-2-Carboxylate (cas# 126910-68-7) is a useful research chemical.

Stability Store in Freezer
Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.

Applications m-Tolylacetic acid is used as a reactant in the diastereoselective preparation of arylmethylene-isoindolinones.
References Anamimoghadam, Ommid, et al.: Beilstein J. of Org. Chem., 13, 2833-2841 (2017)

Applications 4-hydroxy-2-nitrobenzoic acid (cas# 74230-08-3) is a useful research chemical.

Applications 2-Acetylthioisobutyric Acid (cas# 135937-96-1) is a compound useful in organic synthesis.
References Souers, A., et al.: Bioorg. Med. Chem. Lett., 8, 2297 (1998), Deaton, D., et al.: Bioorg. Med. Chem. Lett., 18, 732 (2008),

Applications Methyl Propionylacetate is used in the synthesis of anti-Perol stereospecific reductases that can be used in the asymmettric and environmentally friendly reduction of ketones.
References Nie, Y. et al.: Org. Biomol. Chem., 11, 4070 (2011);

Applications 4,4'-(1,3-Phenylene)dibutanoic Acid is a useful research chemical for organic synthesis and other chemical processes.
References Di R., et al.: Science, 356, 426 (2017), Schimelpfenig, C. W., et al.: J. Org. Chem., 40, 1493 (1975)

Applications A caged, photolabile Nitric Oxide donor that is useful for delivering nitric oxide into intracellular compartments in microsecond time scale without any cytotoxic effects.
References Namiki, S., et al.: Bioorg. Med. Chem., 7, 1695 (1999),

Applications Used for production of peptide thioester.
References Gaeta, A., et al.: Bioorg. Med. Chem. Lett., 20, 4649 (2010),

Applications 5-Chlorohexanoic acid CAS#: 112176-22-4 is a building block used in organic synthesis.
References Liang, S., et al., Green Chemistry., 20, 680 (2018)

Applications Allylboronic acid pinacol ester
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications tert-Butyl 2-(3-Aminophenyl)acetate can be used as anti-heparanase to treat diseases and disorders associated with heparanase activity.
References Giannini, G., et.al.: PCT Int. Appl., 103, (2018);

Impurity Mesna EP Impurity C
Applications 2-Acetylthioethanesulfonic Acid (Mesna EP Impurity C) is an impurity in the synthesis of Mesna (M225750), used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.
References Tekeres, M., et al.: Clin. Ther., 4, 56 (1981), Brock, N., et al.: Eur. J. Cancer Clin Oncol., 18, 1377 (1982), James, C.A., et al.: Br. J. Clin. Pharmacol., 23, 561 (1987);

Applications 5-Chloronicotinic Acid is used as reagent/reactant luminescence and hydrothermal preparation of cobalt/cadmium/lead chloronicotinate phenanthroline MOF.
References Gao, Z.Q., et al.: J. Solid State Chem., 241, 121-130 (2016)

Applications A redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide. A useful synthetic intermediate for the preparation of novel antiinflammatory agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gough, J.D., et al.: JACS, 124 (15), 3885 (2002)

Applications Used in the preparation of herbicides.

Applications 2-PHENYLNICOTINIC ACID (cas# 33421-39-5) is a useful research chemical.

Applications 6-Fluoronicotinic acid

Applications Intermediate in the preparation of nitro substituted quinazolones.
References Sirisoma, N., et al.: J. Med. Chem., 52, 2341 (2009), Zeng, X., et al.: Bioorg. Med. Chem. Lett., 20, 6282 (2010),

Applications 3-Furoic Acid, is metabolized by Corynebacterium fascians from soil, limonoid metabolism based on a biological studies.
References Hasegawa, S., et al.: J. Arg. Food Chem., 31, 807 (1983)