6-membered Rings

<p>Applications 3-(Cyclopropylaminocarbonyl)phenylboronic acid<br></p>

<p>Applications 3-Acetylphenylboronic acid<br></p>

<p>Stability Volatile<br>Applications Cyclohexyl Propionate (cas# 6222-35-1) is a useful research chemical.<br></p>

<p>Applications N-Carbobenzoxy-1,4-diaminobutane HCl is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia.<br>References Teranishi, H.; et al.: PCT Int. Appl. 215 pp. Patent 2004 CODEN:PIXXD2<br></p>

<p>Stability Hygroscopic<br>Applications Diphenylphosphinodithioic acid is used in the extraction of rhodium from nitrate media using phosphinic acids. It also functions as a new materials for microelectronic and molecular electronic devices.<br>References Samuels, A. C., et al.: Solvent Extraction and Ion Exchange, 33, 418 (2015)<br></p>

<p>Applications (3,5-Dimethoxyphenyl)acetonitrile (cas# 13388-75-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-N,N-Diphenylamino-ß-phenylstilbene (cas# 89114-90-9) is a compound useful in organic synthesis.<br></p>

<p>Applications trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.<br>References Dossetter, A.G., et al.: J. Med. Chem., 55, 6363 (2012); Shao, P.P., et al.: Bioorg. Med. Chem. Lett., 15, 1901 (2005)<br></p>

<p>Applications Butyl Benzenesulfonate is an aryl-sulfonic acid ester found in drug substances. Butyl Benzenesulfonate is also used as a plasticizer in concrete preparation.<br>References Taylor, G.E. et al.: J. Chrom. A, 1119, 231 (2006); Gentsler, I.V. et al.: Izvest. VOZOV Stroit. Arkhit., 1, 67 (1970);<br></p>

<p>Applications 4'-Hydroxyazobenzene-4-carboxylic acid hydrate<br></p>

<p>Applications Hydrobromide salt of Triphenylphosphine, used in the preparation of uridine derivatives as substrate donor analogs of UDP-sugars for glycosyltransferases. Also used in the preparation of tensioactive and antibacterial deoxyglycoside compounds via catalysis.<br>References Wandzik, I. et al.: Bioorg. Chem., 37, 211 (2009); Martins, A. et al.: Eur. J. Org. Chem., 2014, 1448, 2013<br></p>

<p>Applications 4-(Cyanophenyl)boronic Acid Pinacol Ester is used to prepare arylparacyclophanes via Suzuki aryl cross-coupling of bromoparacyclophane with arylboronic acid and arylboronates. It’s also used to prepare tyrosine-modified analogs of α4β7 integrin inhibitor biotin-R8ERY.<br>References Roche, A., et al.: Org. Biomol. Chem.,, 3, 515 (2005); Papst, S., et al.: Bioorg. Med. Chem., 20, 5139 (2012)<br></p>

<p>Applications Methyl 2-Amino-3,4,5-trimethoxybenzoate could be a constituent contributing to the aroma of green tea leaves.<br>References Hasegawa, T., et al.: J. Food Eng., 4, 10 (2014)<br></p>

<p>Applications N-BENZYLBENZAMIDE (cas# 1485-70-7) is a useful research chemical.<br></p>

<p>Applications 2-Ethoxy-4-ethoxysulfonylbenzoic Acid is a derivative of Methyl 2-Ethoxybenzoate (M220113), a useful chemical reagent, used in the synthesis and antibacterial triazoles and oxadiazoles, as well as sulfonamide compounds.<br>References Shi, Z. et al.: Compt. Rend. Chim., 18, 1320 (2015);<br></p>

<p>Applications 2-[6-(Acetylphenylamino)-1,3,5-hexatrienyl]-1,1-dimethyl-3-sulfobutyl-1H=-benz[e]indolium Inner Salt is a reactant used in the preparation of indocyanine green as an infrared probe.<br>References Suganami, A. et al.: Bioorg. Med. Chem. Lett., 22, 7481 (2012); Doi, T. et al.: Synlett., 23, 306 (2012);<br></p>

<p>Applications 4-(Acetamidomethyl)benzoic acid<br></p>

<p>Applications 4-Formylbenzenesulfonic Acid is used in preparation method for 3-Phenyl-L-serine derivatives.<br>References Xu, W., et al.:PCT Int. Appl., (2020):<br></p>

<p>Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.<br>References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides &amp; Nucleotides, 2, 21 (1983)<br></p>

<p>Applications Methyl 3-(Hydroxymethyl)benzoate is used in the synthetic preparation of N-acylhydrazone derivatives as lactate dehydrogenase A inhibitors.<br>References Rupiani, S., et al.: J. Med. Chem., 101, 70 (2015)<br></p>

<p>Applications 4-benzylcyclohexan-1-one (cas# 35883-77-3) is a useful research chemical.<br></p>

<p>Applications Methyl-2-bromo-4-bromomethylbenzoate<br></p>

<p>Applications m-Xylene-2,4,6-triol is a reagent used to synthesize a series of flavanone derivatives that show anti-tumor activities.<br>References Shi, L., et al.: Biorgan. Med. Chem. Lett., 20, 5466 (2010)<br></p>

<p>Applications Perphenylcyclopentasilane is an intermediate in the synthesis of Cyclopentasilane (C988380), a reagent used for depositing silicon on surfaces for electronics applications.<br>References Morisaki, Y., et al.: Chem. Lett., 38, 498 (2009);<br></p>

<p>Applications 1-​(3-​Hydroxyphenyl)​-​1-​propanone is a reactant used to synthesize tricyclic fused pyridines, a family of alkaloids with antimalarial activity.<br>References Zheng, L., et al.: J. Org. Chem., 81, 8911-8919 (2016)<br></p>

<p>Applications A hydroxy derivative of dibenzothiophene. Coal model compound used in chemical coal cleaning studies with molten hydroxides.<br>References Nowak, M.A. et al.: Coal Prep., 7, 29 (1989); Nishioka, M. et al.: Anal. Chem., 57, 1327 (1985);<br></p>

<p>Applications N-{2-[(4-Hydroxyphenyl)sulfanyl]ethyl}acetamide (cas# 91281-32-2) is a useful compound for use as a skin-lightening agent; cosmetic applications.<br>References Parvez, S., et al.: Phytother. Res., 20, 921 (2006)<br></p>

<p>Applications o-Iodochlorobenzene is a building block that has been used as a reactant for the synthesis of biaryl derivatives of seasamol used for their antioxidant activity against DPPH radical.<br>References Rodriguez, S.A., et. al.: Australian J. Chem., 66, 1334 (2013)<br></p>

<p>Applications 4'-Hydroxybiphenyl-3-carboxylic Acid is a biaryl compound that can be prepared via palladium bis[(dipiperidinylphosphino)amino]phenyl-catalyzed Suzuki-Miyaura cross coupling reactions of organoboronic acids or trifluoroborates and aryl bromides and can also be synthesized by simultaneous hydroxylation and carboxylation of biphenyls. 4'-Hydroxybiphenyl-3-carboxylic Acid is a useful building block with applications in various syntheses.<br>References Shibahara, F., et al.: Org. Lett., 6, 2437 (2004); Bolliger, J., Frech, C.: Adv. Synth. Catal., 352, 1075 (2010);<br></p>

<p>Applications 4-Nitrobenzyl Acetoacetate acts as a reagent in the preparation of panipenem via esterification of nitrobenzyl alcohol followed by substitution, cyclizations and hydrogenation. Panipenem I is a new carbapenem antibiotic for the treatment of inflammation.<br>References Fang, H., et al.: hongguo Yaowu Huaxue Zazhi, 21, 216 (2011)<br></p>

<p>Applications 3-Hydroxybenzyl Alcohol, is shown to have antioxidant and free radical scavenging activity.<br>References Dhiman, S., et al.: Chemi-Bio. Interac., 182, 119 (2009); Alfaro, C., et al.: Mutation Res., 539(1-2), 187 (2003);<br></p>

<p>Applications N-(4-Chlorophenyl)-2,6-Difluorobenzamide (cas# 122987-01-3) is a useful research chemical.<br></p>

<p>Applications 4-(Morpholin-4-yl)cyclohexanone is a useful synthetic intermediate. It was used to synthesize diastereomeric 3,6-diaminobicyclo[3.1.0]hexane derivatives.<br>References Vilsmaier, E., et al.: Synthesis, 12, 1142 (1991)<br></p>

<p>Applications Diphenyl Diselenide is an organoselenium compound with pharmacological properties, including antioxidant, glutathione peroxidase-mimetic, and neuroprotective effects. Studies show that Diphenyl Diselenide has demonstrated anxiolytic effects in rodents and can inhibit biofilm formation by Candida albicans, increasing both ROS production and membrane permeability.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hassan, W., et al.: Eur. J. Pharmacol., 761, 341 (2015); Rosseti, I.B., et al.: J. Trace Elem. Med. Bio., 29, 289 (2015); Ibrahim, M., et al.: Prog. Neuro-Psychoph., 54, 187 (2014)<br></p>

<p>Applications Benzenecarbothioic Acid is used in the preparation of anti-leishmanial activity. Also used in the preparation of agents for the treatment against Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andrews, P. et al.: Aus. J. Chem., 66, 1297 (2013); Linning, P. et al.: Org. Biomol. Chem., 10, 8216 (2012);<br></p>

<p>Applications 4-(2-Hydroxy-1,1-dimethylethyl)benzenesulfonamide (cas# 374067-96-6) is a compound useful in organic synthesis.<br>References Morimoto, H., et al.: J. Med. Chem., 44, 3369 (2001),<br></p>

<p>Applications A useful building block for oligoribonucleotide synthesis.<br>References Shestopalov, I., et al.: Nat. Chem. Biol., 3, 650 (2007),<br></p>

<p>Applications β-oxo-Cyclohexanepropanenitrile is used in the preparation of pyrazoloquinazolinone derivatives as PARP-1 inhibitors. In addition, it is used in the preparation of benzoxazoyl amino cyanopyrimidines which act as negative allosteric mGlu5 modulators. Used in anxiety, depression and addiction treatment.<br>References Orvieto, F. et al.: Bioorg. Med. Chem. Lett., 19, 4196 (2009); Mueller, R. et al.: ChemMedChem., 7, 406 (2012);<br></p>

<p>Applications 5-Fluoro-2-mercaptobenzothiazole is used as a reagent in the synthesis of [[(benzothiazolyl)thio]methyl]phenyl]furanone derivatives with agrochemical fungicidal activities.<br>References Zhao, P., et al.: Youji Huaxue, 30, 1567 (2010);<br></p>

<p>Applications An intermediate in the preparation of Digallic Acid<br></p>

<p>Applications 2-Biphenylisocyanate (cas# 17337-13-2) is a useful research chemical.<br></p>

<p>Applications It can be used in the preparation of sanitizer for use in factories.<br>References Yuan, H., et al.: Sanitizer used in factory and preparation method thereof, CN 106038470 (2016)<br></p>

<p>Applications Benzyltriphenylphosphonium bromide is a useful reactant and reagent for organic reactions and synthesis.<br>References Hajra, S., et al.: Chem. Comm., 47, 3981-82 (2011); Smith, M.J., et al.: Org. Lett., 2011, 13, 3396-98;<br></p>

<p>Applications Dibenzosuberyl Chloride is used in the synthesis of atypical tricyclic antidepressant as well as dibenzosuberyl-substituted tropines as ligands for acetylcholine-binding protein. Dibenzosuberyl Chloride is also used in the preparation of amino protecting group for solid phase peptide synthesis.<br>References Gerdes, K. et al.: Int. Elec. Conf. Synth. Org. Chem., 596 (2004); Noda, M. et al.: Shim. Hyor., 54, 223 (1997); Edink, E. et al.: Bioorg. Med. Chem. Lett., 22, 1448 (2012);<br></p>

<p>Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.<br>References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)<br></p>

<p>Applications 1-Phenyl-2-(p-tolyl)ethylamine is an intermediate used to prepare γ-nitroaldehydes with quaternary stereogenic centers.<br>References Angewandte Chemie, International Edition, 52, 7228 (2013)<br></p>

<p>Stability Store FROZEN<br>Applications Material that was assayed to be approximately 80% pure was diluted to 5% in benzene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-(2-Benzyloxyphenoxy)ethylamine (cas# 72955-81-8) is a compound useful in organic synthesis.<br></p>

<p>Applications methyl 4-(bromomethyl)-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas# 1626407-50-8) is a useful research chemical.<br></p>

<p>Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.<br>References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);<br></p>

<p>Applications Ethyl Benzoylformate is a general chemical reagent used in the preparation of diaminoethanediyl bismethylpyridinium salts for designing recyclable organocatalysts.<br>References Lisnyak, V. et al.: J. Org. Chem., 80, 8570 (2015);<br></p>

<p>Applications 4-phenyloxolan-2-one (cas# 1008-73-7) is a useful research chemical.<br></p>

<p>Applications N-Benzyloxycarbonyl-5-(3-acetamido-6-benzyloxypenyl)cysteine Methyl Ester (cas# 37398-28-0) is a compound useful in organic synthesis.<br></p>

<p>Applications (Methyl)triphenylphosphonium Iodide is the precursor to a wittig reagent.<br></p>

<p>Stability Light Sensitive<br>Applications 1,3-Cyclohexadiene (cas# 592-57-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-(1-(Ethylamino)cyclohexyl)phenol is a useful synthesis intermediate.<br></p>

<p>Impurity Ketoprofen EP Impurity G<br>Applications 3-​(2-Hydroxyethyl)​benzoic Acid (Ketoprofen EP Impurity G) is an impurity in the synthesis of Ketoprofen (K200800), anti-inflammatory (1,2); analgesic.<br>References 1. Ueno, K. et al.: J Med Chem. 1976 Jul;19(7):941-6. 2. Jamali, F. et al.: Clin Pharmacokinet. 1990 Sep;19(3):197-217.<br></p>

<p>Applications 2-(diphenylacetyl)-3-hydrazino-1H-Inden-1-one is a useful chemical reagent.<br></p>

<p>Applications Ethyl 2-(2,6-Dichlorophenyl)acetate (cas# 90793-64-9) is a useful research chemical.<br></p>

<p>Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.<br></p>

<p>Applications BENZYL CYANOMETHYLCARBAMATE (cas# 3589-41-1) is a useful research chemical.<br></p>

<p>Applications 5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-Dioxide is used in the structure-based design of protein tyrosine phosphatase-1B inhibitors.<br>References Black, E. et al.: Bioorg. Med. Chem. Lett., 15, 2503 (2005);<br></p>