6-membered Rings

<p>Applications 3-Phenylcyclohexanone (cas# 20795-53-3) is a useful research chemical.<br></p>

<p>Applications 6-(4-Phenylbutoxy)-1-hexanamine is an intermediate in the synthesis of salmeterol (S090100), a structural analog of Albuterol (A514500).<br>References Goswami, J., et al.: Tetrahedron. Asym., 12, 3343 (2002);<br></p>

<p>Applications Di-[2-(2,3-dichlorophenyl)aminoethyl]amine is prepared from 1-Bromo-2,3-dichlorobenzene(B687435) and Diethylenetriamine (D444255). 1-Bromo-2,3-dichlorobenzene is a reagent used in the preparation of selective nonpeptidic inhibitors of striatal-enriched protein tryosine phosphatase.<br>References Baguley, T.D., et al.: J. Med. Chem., 56, 7636 (2013)<br></p>

<p>Applications N-(3,4-dimethylphenyl)acetamide (cas# 2198-54-1) is a useful research chemical.<br></p>

<p>Applications 4-Amino-1,3-benzenedisulfonic Acid is used as a reagent in the synthesis of arylazopyridoxal phosphate and phosphonate derivatives as P2 receptor antagonists.<br>References Kim, Y., et al.: Drug Develop. Res., 45, 52 (1998)<br></p>

<p>Applications 5-Chloro-2-fluorobenzoic Acid (cas# 394-30-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,3-DIPHENYLPROPANOL (cas# 20017-67-8) is a useful research chemical.<br></p>

<p>Applications b-Phenylethyl Furoate (cas# 7149-32-8) is a useful research chemical.<br></p>

<p>Applications 1,4-Dicyanobenzene is used in the preparation of aryl nitriles.<br>References Lee, H.G., et. al.: J. Am. Chem. Soc., 137, 648 (2015)<br></p>

<p>Applications 4-Acetamidobenzyl Alcohol is a useful research chemical, a metabolites of a blocked chloramphenicol producer.<br>References Lewis, E. A., et al.: J. Nat. Prod., 66, 62 (2003)<br></p>

<p>Applications ethyl 3-(4-chlorophenyl)-3-oxopropanoate (cas# 2881-63-2) is a useful research chemical.<br></p>

<p>Applications 3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylic acid (cas# 134997-87-8) is a useful research chemical.<br></p>

<p>Applications (2-Decyl)benzene is a linear alkylbenzene used to synthesize aryl olefins.<br>References Faghihian, H., et al.: App. Surface. Sci., 264, 492 (2013);<br></p>

<p>Applications Ethyl α-Bromo-β-phenylpropionate 90% (cas# 39149-82-1) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Benzylformamide is a useful synthetic intermediate. It is used to prepare thiadiazolidinone derivatives as possible glycogen synthase kinase 3 inhibitors. It can also be used to synthesize selective antitubercular agents.<br>References Martinez, A., et al.: J. Med. Chem., 48, 7103 (2005); Karabanovichi, G., et al.: Eur. J. Med. Chem., 82, 324 (2014)<br></p>

<p>Applications N-Benzylaniline is a major metabolite of the antihistaminic Antazoline and other N-substituted benzylanilines.<br>References Ali, H.M. et al.: J. Chrom., 202, 287 (1980); Kucukguzel, I. et al.: J. Fac. Pharm. Istan. Univ., 32, 69 (1998);<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(2-oxopropyl)-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione (cas# 57384-79-9) is a useful research chemical.<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications tert-Butyl 2-(3-Aminophenyl)acetate can be used as anti-heparanase to treat diseases and disorders associated with heparanase activity.<br>References Giannini, G., et.al.: PCT Int. Appl., 103, (2018);<br></p>

<p>Stability Store in freezer at -20°C<br>Applications A synthetic intermediate<br></p>

<p>Applications 2,3-Dimethylphenylacetic Acid (cas# 30981-98-7) is a compound useful in organic synthesis.<br></p>

<p>Applications hexyl 4-aminobenzoate (cas# 13476-55-6) is a useful research chemical.<br></p>

<p>Applications 4-Acetylphenylboronic acid4-Acetylphenylboronic Acid is used in several metal catalyzed cross-coupling reaction studies.<br>References Saito, S., et al.: J. Org. Chem., 2, 8024 (1997); Sakai, M., et al.: Organomet., 16, 4229 (1997); Molander, G., et al.: J. Org. Chem., 68, 4302 (2003);<br></p>

<p>Applications Methyl 4-(trifluoromethyl)benzoate<br></p>

<p>Applications Methyl 5-chloro-2-nitrobenzoate<br></p>

<p>Applications sec-Butylbenzene is used as the starting material in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000). sec-Butylbenzene is also used as the sole carbon and energy source for certain Pseudomonas bacteria strains (1,2). Environmental pollutant.Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Baggi, G. et al.: Biochem J. 1972 Mar;126(5):1091-7.2. Yang, S. et al.: Environ Technol. 2016;37(9):1045-53.<br></p>

<p>Applications Methyl 3-hydroxy-4,5-dimethoxybenzoate (cas# 83011-43-2) is a useful research chemical.<br></p>

<p>Applications 2-Dibenzyloxyphosphanylacetic acid (cas# 53243-58-6) is a useful research chemical.<br></p>

<p>Applications Used as a building block for the preparation of 4H-pyrans, 2-pyridones, furans and carbocyclics.<br>References Herschhorn, A., et al.: J. Med. Chem., 50, 3402 (2007),<br></p>

<p>Applications Methyl phenyl sulfone (cas# 3112-85-4) is a useful research chemical.<br></p>

<p>Applications Phenylacetyl disulfide (cas# 15088-78-5) is a useful research chemical.<br></p>

<p>Applications 4,4'-Dithiobisbenzoic Acid Dimethyl Ester (cas# 35190-68-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-[3-(Hydroxymethyl)phenoxy]benzonitrile can be synthesized from 4-(3-Formylphenoxy)benzonitrile (90178-72-6).<br></p>

<p>Applications 2-(Aminosulfonyl)benzoic Acid can be used as reactant/reagent in synthesis and pharmacological activity of γ-(phenyloxamido)- and γ-(phenylsulfonyloxamido)butanoic acids.<br>References Georgiyants, V. A., et al.: Farmatsevtichnii Zhurnal, 2, 34 (2010);<br></p>

<p>Applications Phenyl Cyanate (Stabilized with PPE) (cas# 1122-85-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Bromodifluoromethyl Phenyl Sulfone can be used to prepare difluoromethyl ethers via difluoromethylation of alcohols.<br>References Xie, Q., et.al.:Angew. Chem. Int., 56, 3206-3210, (2017);<br></p>

<p>Applications 2-PHENYLQUINAZOLIN-4(3H)-ONE (cas# 1022-45-3) is a useful research chemical.<br></p>

<p>Applications 2-Amino-5,5-dimethyl-5,6-dihydro-4h-benzothiazol-7-one<br></p>

<p>Applications Dibenzoylmethane is a compound known to inhibit tumorigenesis in mice.<br>References Lin, C. C., et al.: Cancer Lett., 168, 125 (2001)<br></p>

<p>Applications Ethyl 4-acetylbenzoate is used as a reagent to synthesize pyrazoles (e.g. 1H-Pyrazole [P842195]). Ethyl 4-acetylbenzoate is also used as a reagent to synthesize chiral hydrazines (e.g. (S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde [B288000]) from the catalytic enantioselective hydrogenation of N-alkoxycarbonyl hydrazones.<br>References Heller, S. &amp; Natarajan, S.: Org. Lett., 8, 2675 (2006); Yoshikawa, N., et al.: Org. Lett., 12, 276 (2010)<br></p>

<p>Applications 4,4'-(1,3-Phenylene)dibutanoic Acid is a useful research chemical for organic synthesis and other chemical processes.<br>References Di R., et al.: Science, 356, 426 (2017), Schimelpfenig, C. W., et al.: J. Org. Chem., 40, 1493 (1975)<br></p>

<p>Applications 1,2,4-Triacetoxybenzene, can be used in preparation of two marine aminated hydroxynaphthazarins, echinamines A and B.<br>References Pokhilo N. D., et al.: Journal of natural products, 69(8), undefined (2006-8-29);<br></p>

<p>Stability Hygroscopic<br>Applications Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Pfefferkorn, J., et al.: J. Med. Chem., 51, 31 (2008);<br></p>

<p>Applications 4-Hydroxy-3,5-dimethylbenzoic Acid is used in the synthesis of Mexiletine (M340800) derivatives as orally bioavailable inhibitors. Also, used as a chemical reagent in the preparation of potent transthyretin (TTR) amyloidogenesis inhibitors affecting thyroid hormone.<br>References Frederickson, M. et al.: J. Med. Chem., 51, 183 (2008); Johnson, S. et al.: J. Med. Chem., 51, 260 (2008);<br></p>

<p>Applications 5-Bromo-2-fluorobenzonitrile<br></p>

<p>Applications methyl 5-oxo-5-phenylpentanoate (cas# 1501-04-8) is a useful research chemical.<br></p>

<p>Applications Intermediate in the production of Gallic Acid derivatives.<br>References Dodo, K., et al.: Bioorg. Med. Chem., 16, 7975 (2008), Dodo, K., et al.: Chem. Pharm. Bull., 57, 190 (2009),<br></p>

<p>Applications A useful synthetic intermediate.<br></p>

<p>Applications N-Benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine D4 receptor. It is also a reagent for enantioselective synthesis of epoxides and piperazinones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mammoli, V., et al.: ChemMedChem 11, 1819 (2016); Meninno, S., et al.: Org. Lett. 17, 4348 (2015)<br></p>

<p>Applications 2,3-Dihydroxy-7-sulphamoyl-benzo[f]quinoxaline (cas# 118876-57-6) is a compound useful in organic synthesis.<br></p>

<p>Stability Air Sensitive<br>Applications 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one (cas# 569-77-7) is a useful research chemical.<br></p>

<p>Applications Benzyl Isocyanate is a general reagent used in the synthesis of complex bisindolylmethanes. Also used in the preparation of urea derivatives of thiazol-2-ethylamines for their anti-trypanosomal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Patrick, D. et al.: Bioorg. Med. Chem., 24, 2451 (2016);<br></p>

<p>Applications Intermediate in the preparation of various antidepressants and protein kinase inhibitors.<br>References Kojima, T., et al.: Chem. Pharm. Bull., 33, 3766 (1985), Jinbo, Y., et al.: J. Med. Chem., 37, 2791 (1994),<br></p>

<p>Applications Intermediate in the preparation of Trimebutine metabolites.<br></p>

<p>Applications Methyl Dimethylbenzeneacetate (cas# 57625-74-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Tetrahydro-4-pyranol is a building block of various organic compounds and pharmaceuticals.<br>References Chan, A.W., et al.: J. Med. Chem., 53, 3086 (2010); Desjardins, A.E.. et al.: Phytochem., 27, 767 (1988);<br></p>

<p>Applications (4-Ethynylphenyl)trimethylsilane (cas# 16116-92-0) is a useful research chemical.<br></p>

<p>Applications N2-Acetyl-O6-diphenylcarbamoylguanine is a reactant in the synthesis of 1',2'-oxetane-nucleosides bearing 2'-C-Me substituents with anti-HCV activity.<br>References Komsta, Z., et. al.: Tetrahedron Lett., 55, 6216 (2014)<br></p>

<p>Applications 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol is used in the preparation of fluorescent N/S acyl derivatives.<br>References 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)thio]ethanamine<br></p>

<p>Applications 4-(Cyclopropylcarbonyl)-α,α-dimethylbenzeneacetic Acid is used for the preparation of Terfenadine ((T114500) analogs.<br>References Uchida., et al.: Chem. Pharm. Bull., 37, 958 (1989),<br></p>

<p>Applications Ethyl (E)-Benzohydroximate is a synthetic intermediate and building block used in organic synthesis. It is used as a reactant in the preparation of N-functionalized oxyalkenes.<br>References Sartori, G., Maggi, R.: Science of Synthesis, 32, 783 (2008);<br></p>

<p>Applications Dibenzothiophene-2-boronic acid is a useful reagent for organic synthesis and other chemical processes.<br>References Duncton, M. A. J., et al.: Org. Lett., 10, 3259 (2008)<br></p>

<p>Applications Phenylmethyl ester N-[(3aS,4R,6S,6aR)-tetrahydro-6-hydroxy-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]-Carbamic acid is a useful chiral building block. It has been used in the synthesis of all-cis carbocyclic precursor of ticagrelor via oxidation/stereoselective reduction sequences.<br>References Wlodarczyk, J.; et al.: Tet. Lett., 56, 6093 (2015).<br></p>

<p>Applications N-(1-Chloro-2-oxo-2-phenylethyl)benzamide is an amidophenacylating reagent used in various organic reactions, e.g. in the synthesis of thiohydantoin derivatives.<br>References Balya, A.G., et al.: Russ. J. Gen. Chem., 78, 1427 (2008); Belyuga, A.G., et al.: Zhurnal Organichnoi ta Farmatsevtichnoi Khimii, 2, 25 (2004)<br></p>

<p>Applications BENZOYL CYANIDE (cas# 613-90-1) is a useful research chemical.<br></p>