Pharmaceutical Standards
Pharmaceutical standards are a comprehensive set of reference materials essential for ensuring the safety, efficacy, and quality of pharmaceutical products. This category includes standards for active pharmaceutical ingredients (APIs), which are the core components responsible for therapeutic effects. Additionally, it covers compounds and metabolites relevant to both the pharmaceutical and veterinary industries, providing benchmarks for the accurate measurement and analysis of these substances. Nitrosamine control standards are crucial for detecting and mitigating potentially harmful nitrosamines in drug formulations. Toxicology standards help assess the safety and potential adverse effects of pharmaceutical compounds. Furthermore, enzyme activators and inhibitors standards are vital for research and development, enabling precise studies of biochemical pathways and drug mechanisms. These pharmaceutical standards are indispensable tools for regulatory compliance, quality control, and research, ensuring that pharmaceutical products meet stringent safety and effectiveness criteria.
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(273,300 products)
- Enzyme Activators and Inhibitors(2,827 products)
- Nitrosamines(2,606 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,577 products)
- Toxicology(13,652 products)
Found 7836 products of "Pharmaceutical Standards"
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4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS:Controlled Product<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Formula:C23H26O3Color and Shape:NeatMolecular weight:350.453-Hydroxy-2-naphthoic acid
CAS:Controlled Product<p>Applications 3-Hydroxy-2-naphthoic acid<br></p>Formula:C11H8O3Color and Shape:NeatMolecular weight:188.18Inosine-5'-monophosphate Disodium Salt Hydrate
CAS:Controlled Product<p>Applications Inosine-5'-monophosphate Disodium Salt Hydrate is used in Raman spectra of alkali and alkaline earth metal salts of inosine 5'-monophosphoric acid.<br>References Carmona, P., et al.: J. Raman Spectrosc., 27, 817 (1996)<br></p>Formula:C10H11N4O8PNa·xH2OColor and Shape:NeatMolecular weight:392.17+144.122,2'-Dihydroxy-4,4'-dimethoxybenzophenone
CAS:Controlled Product<p>Applications 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (cas# 131-54-4) is a useful research chemical.<br></p>Formula:C15H14O5Color and Shape:NeatMolecular weight:274.27Cyanidin 3-O-β-D-Galactopyranoside Chloride
CAS:Controlled Product<p>Applications An anthocyanin responsible for red pigment in fruits and berries. It is an antioxidant, protecting the cell against damage from SOD.<br>References Riihinen, K., et al.: Food Chem., 110, 156 (2008), Khanizadeh, S., et al.: J. Food Comp. Anal., 21, 396 (2008), Viskelis, P., et al.: J. Food Sci., 74, C157 (2009), Comeskey, D., et al.: J. Agric. Food Chem., 57, 2035 (2009),<br></p>Formula:C21H21O11·ClColor and Shape:Dark Brown SolidMolecular weight:484.84Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate
CAS:Controlled Product<p>Stability Temperature Sensitive<br>Applications Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate (cas# 1190403-86-1) is a compound useful in organic synthesis.<br></p>Formula:C19H30O10Color and Shape:NeatMolecular weight:418.44N,N-bis(1-naphthylmethyl)aminomethane
CAS:Controlled Product<p>Applications N-Methyl-N-(1-naphthalenylmethyl)-1-naphthalenemethanamine is a reagent used in the synthesis of Butenafine Hydrochloride (B690195) an anti-fungal.<br>References Maeda, T., et al.: Yakugaku Zasshi, 111, 126 (1991).<br></p>Formula:C23H21NColor and Shape:NeatMolecular weight:311.42Cinnamic Acid-13C3
CAS:<p>Applications Cinnamic Acid-13C3 is the labelled analogue of Cinnamic Acid which is rac-form of trans-Cinnamic Acid (P336185) that is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>Formula:C613C3H8O2Color and Shape:White To Off-WhiteMolecular weight:151.141,4-Naphthoquinone-d6
CAS:Controlled Product<p>Applications 1,4-Naphthoquinone-d6 (CAS# 26473-08-5) is a useful isotopically labeled research compound.<br></p>Formula:C10D6O2Color and Shape:NeatMolecular weight:164.194-Benzyloxyacetophenone
CAS:Controlled Product<p>Applications 4-Benzyloxyacetophenone is used in preparation of inhibitors of various proteins such as hepatitis C virus polymerase, glucosylceramide synthase and protein tyrosine phosphatase 1B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deng, Y., et al.: Bioorg. Med. Chem. Lett., 19, 5363 (2009); Lee, L., et al.: J. Biol. Chem., 274, 14662 (2009); Liu, Z., et al.: Bioorg. Med. Chem. Lett., 21, 3755 (2011)<br></p>Formula:C15H14O2Color and Shape:NeatMolecular weight:226.272-(Chloromethyl)naphthalene
CAS:Controlled Product<p>Applications 2-(CHLOROMETHYL)NAPHTHALENE (cas# 2506-41-4) is a useful research chemical.<br></p>Formula:C11H9ClColor and Shape:NeatMolecular weight:176.64N,N'-Bis[3-(trifluoromethyl-4-cyanophenyl]urea
CAS:Controlled Product<p>Applications N,N'-Bis[3-(trifluoromethyl-4-cyanophenyl]urea can be obtained from 5-Amino-2-cyanobenzotrifluoride (A603630) which can be used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.<br>References Xiao, H.-Y., et al.: Bioorg. Med. Chem. Lett., 20, 4491 (2010)<br></p>Formula:C17H8F6N4OColor and Shape:NeatMolecular weight:398.262Protoporphyrin-9
CAS:<p>Stability Light Sensitive<br>Applications Protoporphyrin-9 is the precursor to heme sites and chlorophyll.<br></p>Formula:C34H34N4O4Color and Shape:NeatMolecular weight:562.662-Ketoglutaric Acid-13C1
CAS:Controlled Product<p>Applications Labelled 2-Ketoglutaric Acid is used in enzymic preparation and conversion to radiolabeled isocitric acid<br>References Ehrlich, R.S. et al.: Biochemistry, 26, 3461 (1987);<br></p>Formula:CC4H6O5Color and Shape:NeatMolecular weight:147.09Tenofovir Monohydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Formula:C9H14N5O4P·H2OColor and Shape:NeatMolecular weight:305.23Homogentisic Acid
CAS:<p>Applications An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics.<br>References Knox, W.E., et al.: Biochem. J., 49, 686 (1951), LaDu, B.N., et al.: J. Biol. Chem., 217, 777 (1955)<br></p>Formula:C8H8O4Color and Shape:NeatMolecular weight:168.15N-Nitrososarcosine-d3
CAS:Controlled Product<p>Applications N-Nitrososarcosine-d3 is a labelled carcinogen compound.<br>References Lu, S., et al.: Cancer Res., 46, 1485 (1986), Tricker, A., et al.: Eur. J. Cancer Prev., 6, 226 (1997),<br></p>Formula:C32H3H3N2O3Color and Shape:Light YellowMolecular weight:121.11Carboxymethyl Cellulose Ether Sodium Salt
CAS:Controlled Product<p>Applications Carboxymethyl Cellulose Ether is used as a thickener to enhance rigidity and composition of pharmaceutical compounds as well as the stability of electrode slurries in composite electrodes. Also provides ion-exchange for chromotography media.<br>References Salerno, C. et al.: AAPS PharmSciTech., 11, 986 (2010); Porcher, W. et al. J. Electrochem. Soc., 156, A133 (2009); Wang, H. et al.: Biochem. Biophys. Res. Comm., 342, 349 (2006);<br></p>Formula:C2H4O3•xUnspecified•xNaColor and Shape:Neat3-(4-Hydroxyphenyl)propionic Acid Methyl Ester
CAS:Controlled Product<p>Applications 3-(4-Hydroxyphenyl)propionic Acid Methyl Ester is a useful synthetic intermediate. It can be used to prepare potent and orally available G protein-coupled receptor 40 agonists as potential antidiabetic agents.<br>References Sasaki, S., et al.: J. Med. Chem., 54, 1365 (2011); Christiansen, E., et al.: ACS Med. Chem. Lett., 1, 345 (2010)<br></p>Formula:C10H12O3Color and Shape:NeatMolecular weight:180.2(2-Nitrophenyl)phosphoric Triamide
CAS:Controlled Product<p>Applications (2-Nitrophenyl)phosphoric triamide is used in the preparation of N-phenylphosphoric acid triamides derivatives as agents for regulating or inhibiting enzymatic urea hydrolysis.<br>References Benini, S., et al.: Eur. J. Biochem., 239, 61 (1996), Witte, C., et al.: Plant Physiol., 128, 1129 (2002), Krajewska, B., rt al.: Bioorg. Chem. 35, 355 (2007),<br></p>Formula:C6H9N4O3PColor and Shape:Yellow CrystallineMolecular weight:216.13Diacetyl Bis(2,4-dinitrophenylhydrazone)
CAS:Controlled Product<p>Applications 2,4-Dinitrophenylhydrazone (DNPH) derivative.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Formula:C16H14N8O8Color and Shape:NeatMolecular weight:446.33(R)-(-)-Carvone 4,4,6,6-d4
CAS:Controlled Product<p>Applications (R)-(-)-Carvone-d4 is an intermediate in synthesizing (+)-Limonene-d5 (L461742). It is present in blood oranges which show inhibition of angiogenesis in human colon cancer cells. Extracted from the oils of Mentha spicata it shows antimicrobial activity.<br>References Chidambara Murthy, K. et al.: Life Sci.,91, 429 (2012); Aggarwal, K. et al.: Flav. Frag. J., 17, 59 (2002)<br></p>Formula:C10D4H10OColor and Shape:NeatMolecular weight:154.242Isovaleric anhydride
CAS:Controlled Product<p>Applications Isovaleric anhydride<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C10H18O3Color and Shape:ColourlessMolecular weight:186.25Carboxybutyrolactone
CAS:Controlled Product<p>Applications Carboxybutyrolactone is a structural analog of (±)-Paraconic Acid (P191200) and is used as a reagent in the synthesis of methylenecarboxybutyrolactones which have antibacterial activity.<br>References Tonari, K., et al.: J. Oleo Sci., 51, 259 (2002)<br></p>Formula:C5H6O4Color and Shape:Off-WhiteMolecular weight:130.1Kinetin Riboside
CAS:Controlled Product<p>Applications Used as an anticancer and antiviral agent.<br>References Cancer Res., 20, 1362 (1960), Virology, 38, 26 (1969),<br></p>Formula:C15H17N5O5Color and Shape:NeatMolecular weight:347.332-Fluoroadenosine
CAS:Controlled Product<p>Applications 2-Fluoroadenosine is a fluorinated analog of Adenoside (A280400) nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>Formula:C10H12FN5O4Color and Shape:NeatMolecular weight:285.23Cesium Carbonate
CAS:Controlled Product<p>Applications Cesium Carbonate is used in the preparation of prodrugs based upon phosphonooxymethyl as HIV-1 attachment inhibitors. Also used in the synthesis of dodecahedral nanocrystals as effective antibacterial agents.<br>References Leahy, D. et al.: Org. Proc. Res. Dev., 17, 1440 (2013); He, J. et al.: Dalton Trans., 42, 15637 (2013);<br></p>Formula:Cs2CO3Color and Shape:White To Off-WhiteMolecular weight:325.828-Bromo-2’-deoxyguanosine
CAS:Controlled Product<p>Applications 8-Bromo-2’-deoxyguanosine (cas# 13389-03-2) is a compound useful in organic synthesis.<br>References Chatgilialoglu, C., et al.: Chem. Res. Toxicol., 20, 1820 (2007),<br></p>Formula:C10H12BrN5O4Color and Shape:NeatMolecular weight:346.144-Hydroxy-3-nitrophenylacetic Acid
CAS:Controlled Product<p>Applications A metabolite of Nitrotyrosine (N597000), which is excreted in the urine.<br>References van der Vliet, A., et al.: J. Biol. Chem., 272, 7617 (1997), Tabrizi-Fard, M., et al.: Drug Metab. Dispos., 27, 429 (1999), Souza, J., et al.: Arch. Biochem. Biophys., 380, 360 (2000),<br></p>Formula:C8H7NO5Color and Shape:NeatMolecular weight:197.145-Chloro-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
CAS:Controlled Product<p>Applications Intermediate for synthesis of verapamil and analogs.<br></p>Formula:C16H22ClNO2Color and Shape:NeatMolecular weight:295.802-Naphthylacetic Acid
CAS:Controlled Product<p>Applications 2-Naphthylacetic acid can be used to synthesize hydrolase inhibitors. It can also be utilized for developing γ-dipeptide derivatives that can bind human somatostatin receptors.<br>References Tarzia, G., et al.: J. Med. Chem. 46, 2352 (2003); Seebach, D., et al.: Angew. Chem. Int. Ed. 42, 776 (2003)<br></p>Formula:C12H10O2Color and Shape:NeatMolecular weight:186.21(2E,4Z)-2,4-Decadienoic Acid Methyl Ester
CAS:Controlled Product<p>Applications (2E,4Z)-2,4-Decadienoic Acid Methyl Ester is used in the syntheses of Methyl (R,E)-2,4,5-tetradecatrienoate and Methyl (2E,4Z)-2,4-decadienoate, the pheromone components of the male dried bean beetle, Acanthoscelides obtectus (Say).<br>References Fujisawa, T., et al.: Tetrahedr. Lett., 25, 4007 (1984); Mori, K., et al.: Bioorg. Med. Chem., 15, 7505 (2007);<br></p>Formula:C11H18O2Purity:98%Color and Shape:NeatMolecular weight:182.263,5-Dinitrosalicylic Acid
CAS:Controlled Product<p>Applications 3,5-Dinitrosalicylic Acid (cas# 609-99-4) is a compound useful in organic synthesis.Dyes and metabolites.<br></p>Formula:C7H4N2O7Color and Shape:NeatMolecular weight:228.12trans,trans-2,4-Nonadienal (>90%)
CAS:<p>Applications trans,trans-2,4-Nonadienal is an unsaturated aldehyde that is responsible for the bean odour of soymilk. trans,trans-2,4-Nonadienal has also been identified as a potentially mutagenic substance by inducing oxidative DNA damage.<br>References Sjaastad, A. & Svendsen, K.: Ann. Occ. Hyg., 52, 739 (2008); Vara-Ubol, S., et al.: J. Sens. Stud., 19, 15 (2004); Yang, C., et al.: Chin. J. Physiol., 52, 151 (2009)<br></p>Formula:C9H14OPurity:>90%Color and Shape:YellowMolecular weight:138.21(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3
CAS:Controlled Product<p>Applications (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3 is an intermediate used in the synthesis of Nintedanib Demethyl-O-glucuronic Acid-d3 (N478297), which is an isotopic analog of Nintedanib Demethyl-O-glucuronic Acid (N478295), a metabolite of the drug Nintedanib (N478290).<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formula:C30D3H28N5O4Color and Shape:NeatMolecular weight:528.6172'-Nitroacetophenone
CAS:Controlled Product<p>Applications 2'-Nitroacetophenone (cas# 577-59-3) is a compound useful in organic synthesis.<br></p>Formula:C8H7NO3Color and Shape:NeatMolecular weight:165.15(6R)-6-Methyl-octanoic Acid
CAS:Controlled Product<p>Applications (6R)-6-Methyl-octanoic Acid is an intermediate in synthesizing Colistin A Sulfate Hydrate (C641510), used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.<br>References Wallace, S. et al.: J. Pharm. Sci., 102, 1578 (2013); Suzuki, T., et al.: J. Biochem., 54, 25 (1963); Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964); Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000); Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005); Tsubery, H. et al.: Antimicrob. Agents Chemother., 49, 3122 (2005)<br></p>Formula:C9H18O2Color and Shape:NeatMolecular weight:158.24Sodium Chlorite (Technical Grade)
CAS:<p>Applications Sodium Chlorite is used as a bleaching agent for cotton textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shenai, V.A., Pai, S.M.: Textile Dyer Printer, 3, 153 (1969)<br></p>Formula:ClO2·NaColor and Shape:NeatMolecular weight:90.44162-Methylnaphthalene
CAS:<p>Applications 2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH) that has been used as an indicator of smoke exposure in food and packaging materials. This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Johnston, J.J., et. al.: J. Agr. Food Chem., 42, 1954 (1994)<br></p>Formula:C11H10Color and Shape:WhiteMolecular weight:142.20N-Methyl-4-phenylpyridinium Iodide
CAS:<p>Applications Dopaminergic neurotoxin; a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marini, A.M. et al.: J, Nat. Cancer Inst., 84, 1582 (1992); Singh, M. et al.: Arch. Biochem. Biophys., 286, 138 (1991); Santiago, M. et al.: J. Neurosci. Meth., 108, 181 (2001);<br></p>Formula:C12H12N·IColor and Shape:NeatMolecular weight:297.13trans-Cinnamamide
CAS:Controlled Product<p>Applications trans-Cinnamamide is used in the used in the synthesis of U-77863 and U-77864 as it has antitumor activity.<br>References Harper, D.E., et al.: J. Antibiot., 45, 1827 (1992)<br></p>Formula:C9H9NOColor and Shape:NeatMolecular weight:147.17Iso Cytosine
CAS:Controlled Product<p>Applications A useful intermediate for chemical modifications of base and sugar moieties in natural nucleosides.<br>References Sashaki, T., et al.: J. Org. Chem., 40(1), 106 (1975)<br></p>Formula:C4H5N3OColor and Shape:NeatMolecular weight:111.10Isopilocarpic Acid Sodium Salt
CAS:Controlled Product<p>Impurity Pilocarpine Hydrochloride EP Impurity C<br>Stability Hygroscopic<br>Applications Isopilocarpic Acid is a degradation product of Pilocarpine (P441500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Szepesi, G. et al.: Pharmazie, 38, 94 (1983); Bundgaard, H. et al.: Int. J. Pharmac., 10, 281 (1982);<br></p>Formula:C11H17N2O3·NaColor and Shape:WhiteMolecular weight:248.258-anti-Ipratropium Bromide
CAS:Controlled Product<p>Impurity Ipratropium EP Impurity B<br>Applications 8-anti-Ipratropium Bromide (Ipratropium EP Impurity B) is a related compound to Ipratropium Bromide (I740500), nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.<br>References Groeben, H., et al.: Anesthesiology, 85, 867 (1996), Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999), Barnes, P. J., et al.: Chest, 117, 63S (2000),<br></p>Formula:C20H30NO3·BrColor and Shape:NeatMolecular weight:412.36N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5
CAS:Controlled Product<p>Applications N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5 is labelled N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine (D199030), a derivative of Mertansine (M257800) which is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.<br>References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)<br></p>Formula:C41D5H50ClN4O12SColor and Shape:White To Off-WhiteMolecular weight:868.4449-Nitroanthracene-d9
CAS:Controlled Product<p>Applications 9-Nitroanthracene-d9 (CAS# 220381-38-4) is a useful isotopically labelled research compound. It could be useful for analytical studies that involve detecting nitrated polycyclic aromatic hydrocarbons.<br>References Siegmund, B., et al.: Anal. Bioanal. Chem., 375, 175 (2003)<br></p>Formula:C14D9NO2Color and Shape:NeatMolecular weight:232.297-Hydroxy-1,3-naphthalenedisulfonic Acid Dipotassium Salt
CAS:Controlled Product<p>Applications 7-Hydroxy-1,3-naphthalenedisulfonic acid is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Formula:C10H6O7S2·2KColor and Shape:Off White SolidMolecular weight:380.48Adenosine-13C5
CAS:<p>Stability Hygroscopic<br>Applications Labelled nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010), Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010),<br></p>Formula:C513C5H13N5O4Color and Shape:White To Off-WhiteMolecular weight:272.202,2'-((4-Aminophenyl)azanediyl)diethanol Sulfate
CAS:Controlled ProductFormula:C10H16N2O2·H2O4SColor and Shape:White To Off-WhiteMolecular weight:294.32472,3-Dibromoanthracene
CAS:Controlled Product<p>Applications 2,3-Dibromoanthracene is a useful synthetic intermediate. It is used to synthesize various acenes and acene derivatives such as Acenaphth[1,2-b]anthracene (A130745) which is mutagenic.<br>References Toyota, S., et al.: Sci. Syn., 45, 745 (2010); Durant, J., et al.: Mutat. Res-Genet. Tox., 371, 123 (1996)<br></p>Formula:C14H8Br2Color and Shape:NeatMolecular weight:336.023-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester
CAS:<p>Applications 3-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester is an intermediate in the synthesis of N-Ethyl Esmolol (E918045), which is an impurity of esmolol (E668000), which is a cardioselective β-adrenergic blocker. Antiarrhythmic.<br>References Gorczynski, R.J., et al.: J. Cardiovasc. Pharmacol., 5, 668 (1983), Yacobi, A., et al.: J. Pharm. Sci., 72, 711 (1983), Benfield, P., et al.: Drugs, 33, 392 (1987)<br></p>Formula:C13H16O4Color and Shape:NeatMolecular weight:236.26L-Homoserine Lactone Hydrobromide
CAS:Controlled Product<p>Applications L-Homoserine Lactone Hydrobromide is a reactant in the synthesis of tritium labeled and photoactivatable N-acyl-L-homoserine lactones.<br>References Jakubczyk, D., et. al.: Eur. J. Org. Chem., 592, 2014 (2014)<br></p>Formula:C4H7NO2·HBrColor and Shape:NeatMolecular weight:314.419Cyclamic Acid-d11
CAS:Controlled Product<p>Applications Labelled Cyclamic acid. A non-nutritive sweetener.<br>References Taylor, et al.: Food Cosmet. Toxicol., 6, 313 (1968), Brantom, et al.: Food Cosmet. Toxicol., 11, 735 (1973),<br></p>Formula:C6D11H2NO3SColor and Shape:NeatMolecular weight:190.31(S)-Ramelteon Metabolite M-II
CAS:Controlled Product<p>Applications S-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).<br>References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)<br></p>Formula:C16H21NO3Color and Shape:NeatMolecular weight:275.34Clocortolone Acetate
CAS:Controlled Product<p>Applications Clocortolone Acetate is an intermediate in the synthesis of Clocortolone (C583800), an corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses.<br>References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);<br></p>Formula:C24H30ClFO5Color and Shape:NeatMolecular weight:452.942,2,6,6-Tetramethyl-4-piperidyl Methacrylate
CAS:Controlled Product<p>Applications It is used as cholesterol-lowering agent.<br>References Bauer, D., et al.: Polym Deg. Stab., 48, 259 (1995), Nakahara, K., et al.: Chem. Physics Lett., 359, 351 (2002),<br></p>Formula:C13H23NO2Color and Shape:WhiteMolecular weight:225.33Betamethasone 17-Butyrate
CAS:Controlled Product<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Formula:C26H35FO6Color and Shape:NeatMolecular weight:462.555-Oxorosuvastatin Methyl Ester
CAS:<p>Applications 5-Oxorosuvastatin methyl ester is an intermediate in the synthesis of Rosuvasatatin (calcium salt: R700500), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that decreases high-sensitivity C-reactive protein (hsCRP) and cholesterol concentrations in the blood.<br>References McTaggart, F., et al.: Am. J. Cardiol., 87, 28 (2001); Ridker, P., et al.: Lancet, 373, 1175 (2009)<br></p>Formula:C23H28FN3O6SColor and Shape:Yellow SolidMolecular weight:493.55Atorvastatin Ethyl Ester
CAS:Controlled Product<p>Applications Atorvastatin (A791750) impurity.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);<br></p>Formula:C35H39FN2O5Color and Shape:Off White SolidMolecular weight:586.69Polythiazide
CAS:Controlled Product<p>Applications Polythiazide is a thiazide diuretic. Polythiazide is used in the treatment of hypertension as well as nephrotic syndrome, cirrhosis of the liver, and nutritional edema.<br>References Kaur, J. et al.: J. Ind. Med. Assoc., 48, 13, (1967); Lund-Johansen, P.: Acta Med. Scand., 187, 509 (1970); O'Brien, E.T. et al.: Br. Heart J., 34, 1042 (1972);<br></p>Formula:C11H13ClF3N3O4S3Color and Shape:Off WhiteMolecular weight:439.88Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C31H38ClN7O7S2•xH2OColor and Shape:White To Off-WhiteMolecular weight:720.26Azelastine N-Oxide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Azelastine (A808250).<br>References Heinemann, U. et al.: J. Chrom. B Anal. Tech. Biomed. Life Sci., 793, 389 (2003); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979);<br></p>Formula:C22H24ClN3O2Color and Shape:NeatMolecular weight:397.90Pemetrexed acid
CAS:Controlled ProductFormula:C15H14N4O3Color and Shape:Off-WhiteMolecular weight:298.306β-Hydroxy Progesterone (Contains up to 20% 17α-Hydroxy Progesterone)
CAS:Formula:C21H30O3Purity:>80%Color and Shape:NeatMolecular weight:330.46Testololactone
CAS:Controlled Product<p>Applications Testololactone, is the derivative of Testolactone (T154800), which is an antineoplastic agent that is a derivative of progesterone and is used to treat advanced stage breast cancer.<br>References Dunkel, L.: Mol. Cell. Endocrinol., 254, 207 (2006); Eugster, E. A.: Treat. Endocrinol., 3, 141 (2004); Holbeck, S.L. et al.: Mol. Cancer Therap., 9, 1451 (2010);<br></p>Formula:C19H26O3Color and Shape:White To Light YellowMolecular weight:302.41Hydroxydehydro Nifedipine Carboxylate
CAS:Controlled ProductFormula:C16H14N2O7Color and Shape:NeatMolecular weight:346.295-Chloro Hydrochlorothiazide
CAS:Controlled Product<p>Impurity Hydrochlorothiazide 5-Chloro Impurity<br>Applications Hydrochlorothiazide derivative. Diuretic agent.<br>References Mayer, S.E., et al.: J. Pharmacol. Exp. Therap., 134, 18 (1961),<br></p>Formula:C7H7Cl2N3O4S2Color and Shape:Off White SolidMolecular weight:332.186α-Bromo Beclomethasone Dipropionate
CAS:Controlled Product<p>Impurity Beclomethasone Dipropionate EP Impurity F<br>Applications 6α-Bromo Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity F) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Formula:C28H36BrClO7Color and Shape:White SolidMolecular weight:599.947-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin
CAS:Controlled Product<p>Applications A major metabolite of Irinotecan.<br>References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),<br></p>Formula:C33H38N4O8Color and Shape:Light YellowMolecular weight:618.67686β-Hydroxy Betamethasone
CAS:Controlled Product<p>Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.<br>References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)<br></p>Formula:C22H29FO6Color and Shape:NeatMolecular weight:408.46Olodaterol Hydrochloride
CAS:Controlled Product<p>Applications Olodaterol is a long acting β-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD).<br>References Cazzola, M., et al.: Pharmacol. Rev., 64, 450 (2012); Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010);<br></p>Formula:C21H27ClN2O5Color and Shape:Off-White To Light BrownMolecular weight:422.90Boldenone 17-Sulfate TEA
CAS:Controlled Product<p>Applications The major metabolite of Boldenone, an anabolic steroid.<br>References Fotsis, T., et al.: J. Steroid Biochem., 28, 203 (1987), Song, Y., et al.: Arch. Pharm. Res., 23, 599 (2000), Buiarelli, F., et al.: Anal. Chim. Acta, 526, 113 (2004), Poelmans, S., et al.: Food Addit. Contam., 22, 808 (2005),<br></p>Formula:C19H26O5S•C6H15NColor and Shape:Off-White To BeigeMolecular weight:366.472-(9H-Carbazol-1-yl)acetic Acid
CAS:Controlled ProductFormula:C14H11NO2Color and Shape:NeatMolecular weight:225.243Gentiopicroside
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Gentiopicroside is an anticonvulsant agent present in plant extracts.<br>References Mahendran, G. et al.: Biomed. Res. Int., 2015, 542385 (2014);<br></p>Formula:C16H20O9Color and Shape:NeatMolecular weight:356.32(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester
CAS:Controlled Product<p>Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.<br>References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);<br></p>Formula:C17H17NO4Color and Shape:Off White PowderMolecular weight:299.32Simvastatin Hydroxy Acid Ethyl Ester
CAS:<p>Applications An impurity in Simvastatin (S485000).<br>References Sankar, D. et al.: Asian J. Chem., 21, 4294 (2009); Vuletic, M. et al.: J. Pharmac. Biomed. Anal., 37, 715 (2005);<br></p>Formula:C27H44O6Color and Shape:Off-WhiteMolecular weight:464.639-Chloro Triamcinolone Acetonide
CAS:<p>Applications Triamcinolone Acetonide (T767165) impurity.<br>References Laurent, H., et al.: J. Steroid Biochem., 6, 185 (1975),<br></p>Formula:C24H31ClO6Color and Shape:WhiteMolecular weight:450.95Roflumilast N-Oxide
CAS:Controlled Product<p>Applications Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Formula:C17H14Cl2F2N2O4Color and Shape:NeatMolecular weight:419.21Atropine Sulfate Monohydrate
CAS:Controlled Product<p>Applications Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H23NO3·H2O·H2O4SColor and Shape:White To Light YellowMolecular weight:694.83(S)-(-)-Dropropizine
CAS:<p>Applications S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.<br>References Noel, P.R.B., et al.: Arzneim.-Forsch., 19, 1246 (1969), Cartwright, K., et al.: J. Pharm. Pharmacol., 23, Suppl., 247S (1971), Moreo, GC., et al.: Gazz. Med. Ital., 140, 409 (1981),<br></p>Formula:C13H20N2O2Color and Shape:WhiteMolecular weight:236.312-Methyl Hippuric Acid-d2
CAS:Controlled Product<p>Applications The main labelled metabolite of o-xylene.<br>References Gregus, Z., et al.: Drug Metab. Dispos., 26, 1082 (1998), Gregus, Z., et al.: Xenobiotica, 29, 547 (1999), Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),<br></p>Formula:C10D2H9NO3Color and Shape:White To Off-WhiteMolecular weight:195.21Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate
CAS:Controlled Product<p>Applications Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate is an organophosphate nucleating agent.<br>References Li, J., et al.: Suliao, 43, 47-50 (2014);<br></p>Formula:C29H42O4P·NaColor and Shape:White PowderMolecular weight:508.60Methyl Benzilate
CAS:Controlled Product<p>Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.<br>References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)<br></p>Formula:C15H14O3Color and Shape:Off White PowderMolecular weight:242.272-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid
CAS:Controlled Product<p>Applications 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid is a potential metabolite of Chlorthalidone.<br>References Salado C., et al.: J. Chromatography. Biomed. App., 690, 195 (1997);<br></p>Formula:C14H10ClNO5SColor and Shape:NeatMolecular weight:339.7522-Hydroxy Mifepristone
CAS:Controlled Product<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formula:C29H35NO3Color and Shape:NeatMolecular weight:445.591,3-Diacetyl Aloe-emodin
CAS:Controlled Product<p>Applications 1,3-Diacetyl Aloe-emodin is an intermediate in the synthesis of Aloe Emodin 8-Glucoside which is a anthraquinone glycoside that was investigated for antioxidant activities and neuroprotective properties.<br>References El-Toumy, S.A., et al.: Carb. Res. 360, 47 (2012); Xiang, L., et al: TsingHua. Sci. Tech., 10, 426 (2005); Shi, Y.Q., et al: Anticancer. Res., 21, 2847 (2001);<br></p>Formula:C10H17BO2Color and Shape:NeatMolecular weight:180.052Boldenone Propionate
CAS:Controlled Product<p>Applications Boldenone Propionate is a metabolite of Boldenone (B675100), which is an anabolic steroid.<br>References Watanabe, K., et al.: J. Appl. Bacteriol., 62, 151 (1987) ; Liu, W., et al.: J. Ind. Microbiol., 13, 167 (1994) ; Barthakur, S., et al.: J. Basic Microbiol., 36, 383 (1996); Grinenko, G., et al.: Pharmaceut. Chem. J., 36, 510 (2002) ; de Brabander, H., et al.: Food Addit. Contam., 21, 515 (2004); Le Bizec, B., et al.: Steroids, 71, 1078 (2006);<br></p>Formula:C22H30O3Color and Shape:Off-WhiteMolecular weight:342.47Triacetin-d5
CAS:Controlled Product<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>Formula:C9D5H9O6Color and Shape:NeatMolecular weight:218.2525-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
CAS:Controlled Product<p>Applications 5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide is a photodegradation product of Atorvastatin (A791750).<br>References Cermola, F., et al.: Tetrahedron., 62, 7390 (2006);<br></p>Formula:C33H33FN2O5Color and Shape:NeatMolecular weight:556.62Flurandrenolone Acetate
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formula:C26H35FO7Color and Shape:NeatMolecular weight:478.55Ouabain-d3 (Major)
CAS:Controlled Product<p>Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);<br></p>Formula:C29H41D3O12Color and Shape:White To Off-WhiteMolecular weight:587.675-Formyltetrahydropteroic Acid
CAS:Controlled Product<p>Impurity Calcium Folinate Hydrate EP Impurity E<br>Stability Unstable in Basic Solution<br>Applications 5-Formyltetrahydropteroic Acid is an impurity of Folic Acid (F680300); a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. It also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)<br></p>Formula:C15H16N6O4Color and Shape:NeatMolecular weight:344.332',7'-Difluorofluorescein
CAS:Controlled Product<p>Applications 2',7'-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases.<br>References Pomorski, A., et. al.: Org. Biomol. Chem., 13, 1395 (2015)<br></p>Formula:C20H10F2O5Color and Shape:NeatMolecular weight:368.287Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H22N4O3Color and Shape:NeatMolecular weight:330.385α-Pregnane-3β,20(S)-diol
CAS:Controlled Product<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Formula:C21H36O2Color and Shape:NeatMolecular weight:320.51
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