Pharmaceutical Standards
Pharmaceutical standards are a comprehensive set of reference materials essential for ensuring the safety, efficacy, and quality of pharmaceutical products. This category includes standards for active pharmaceutical ingredients (APIs), which are the core components responsible for therapeutic effects. Additionally, it covers compounds and metabolites relevant to both the pharmaceutical and veterinary industries, providing benchmarks for the accurate measurement and analysis of these substances. Nitrosamine control standards are crucial for detecting and mitigating potentially harmful nitrosamines in drug formulations. Toxicology standards help assess the safety and potential adverse effects of pharmaceutical compounds. Furthermore, enzyme activators and inhibitors standards are vital for research and development, enabling precise studies of biochemical pathways and drug mechanisms. These pharmaceutical standards are indispensable tools for regulatory compliance, quality control, and research, ensuring that pharmaceutical products meet stringent safety and effectiveness criteria.
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(274,923 products)
- Enzyme Activators and Inhibitors(2,827 products)
- Nitrosamines(2,606 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,873 products)
- Toxicology(13,652 products)
Found 7836 products of "Pharmaceutical Standards"
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(2'S)-Nicotine 1-oxide
CAS:(2'S)-Nicotine 1-oxide is a nicotinic acetylcholine receptor agonist that acts as an insecticide. It is used on plants to control aphids, thrips, and other pests. The effects of (2'S)-nicotine 1-oxide on animals are not well studied. This compound is marketed as a dietary supplement for weight loss, although there has been no validation of this claim. The matrix effect of this drug can cause interference in the analysis of urine samples. Nuclear DNA can be used to detect the presence of (2'S)-nicotine 1-oxide in cancer tissue. Analytical methods for quantifying (2'S)-nicotine 1-oxide include gas chromatography with mass spectrometry detection (GC/MS), liquid chromatography with tandem mass spectrometry detection (LC/MS/MS), and liquid chromatography with ultraviolet detection (LC/UV).Formula:C10H14N2OPurity:Min. 95%Color and Shape:PowderMolecular weight:178.23 g/molErythrosin B
CAS:Erythrosin B is a fluorescent dye that is used in biological research. It has been shown to have cytotoxic effects on human leukemia cells (HL-60) and cytotoxic effects on human lymphocytes. The toxicities of this compound are dependent on the concentration and the duration of exposure, as well as the type of biological sample. Erythrosin B can be used to detect DNA damage in cells by using an analytical method called matrix effect synchronous fluorescence. This dye appears to be genotoxic in vitro and in vivo, but its long-term toxicity is unknown. Erythrosin B has antimicrobial properties against gram-positive bacteria and fungi, but it does not have any activity against Gram negative bacteria or viruses.Formula:C20H8I4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:835.89 g/molTropinone
CAS:Tropinone is a polycyclic aromatic hydrocarbon that is found in plant cells. Tropinone exhibits enzyme activities, such as catalase and peroxidase activity, which are important for plant physiology. Tropinone has also been shown to have anti-cancer properties. Platinum-based chemotherapy drugs bind to the tropinone molecule, which inhibits the enzymes that allow cancer cells to grow and multiply. The specific antibody binds to the tropinone molecule by recognizing a carbohydrate group on the molecule's surface, while hydroxyl groups on the tropinones react with trifluoromethanesulfonic acid in water to form ester hydrochloride. This reaction is dependent on pH level and optimum ph is around 7-9.Formula:C8H13NOPurity:Min. 98%Color and Shape:White PowderMolecular weight:139.19 g/mol1-[(4-Nitrophenyl)methyl]-1H-1,2,4-triazole
CAS:1-[(4-Nitrophenyl)methyl]-1H-1,2,4-triazole (NPT) is a drug that is used to treat migraine. It is an effective and fast acting drug that has been shown to be more efficient than other triptans. NPT inhibits the uptake of serotonin by binding to its receptors in the brain and causing vasoconstriction. The compound has been found to be safe for use in humans. However, it may cause impurities such as genotoxic nitro groups which are harmful to cells if present at high concentrations. There are various techniques that can be used to measure the kinetics of NPT and determine whether it has been hydrogenated during synthesis or not. These include calibration curves, HPLC, and GC methods.Formula:C9H8N4O2Purity:Min. 95%Molecular weight:204.19 g/molO-tert-Butyl-D-tyrosine
CAS:<p>O-tert-Butyl-D-tyrosine is an organogelator. It is a low molecular weight organic liquid that can form a gel when mixed with a solvent. O-tert-Butyl-D-tyrosine is soluble in hydrophobic solvents such as butanol, and insoluble in water. The gelation properties of this substance are due to its ability to interact with the surface of the solvent droplet and form a network that holds other solute molecules in place. This interaction is called physisorption, which means that it does not need any chemical bonds to form the gel. Gels formed by O-tert-Butyl-D-tyrosine are stable at room temperature, but will melt when heated or exposed to pH extremes.</p>Formula:C13H19NO3Purity:Min. 95%Molecular weight:237.29 g/mol6-O-Methyl codeine
CAS:Controlled Product<p>6-O-Methyl codeine is a drug that belongs to the class of opioid analgesics. It is used to treat severe pain and coughing in patients with infectious diseases, such as pneumonia or bronchitis. 6-O-Methyl codeine may be administered by mouth, intravenously, or intramuscularly. The mechanism of action of this drug is not fully understood, but it has been shown to decrease respiratory rate in some animal studies. 6-O-Methyl codeine also has an effect on the central nervous system and may cause dizziness, drowsiness, nausea, vomiting and constipation. This drug is metabolized through oxidative reactions with oxygenated molecules like fluorine or hydrogenated aromatic hydrocarbons. 6-O-Methyl codeine is a prodrug that can be converted into morphine following cleavage by liver enzymes.</p>Formula:C19H23NO3Purity:Min. 95%Molecular weight:313.39 g/mol2-Cyclohexyl-4,6-dinitrophenol
CAS:2-Cyclohexyl-4,6-dinitrophenol is a chemical that inhibits the synthesis of viral DNA. It has been shown to have minimal toxicity in animal models and may be used for the treatment of metabolic disorders, such as hepatic steatosis or hepatitis. 2-Cyclohexyl-4,6-dinitrophenol has also been shown to inhibit the toll-like receptor (TLR) pathway and induce an antiviral state in vitro. In addition, it was found to have an effect on mitochondrial membrane potential, which may explain its antiviral activity. 2-Cyclohexyl-4,6-dinitrophenol has also been shown to inhibit viral replication in cells infected with HIV and other viruses such as Hepatitis C virus.Formula:C12H14N2O5Purity:Min. 95%Molecular weight:266.25 g/mol3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate
CAS:Controlled Product3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate is a short-acting intravenous anaesthetic that is used in surgical procedures. It has been shown to have antinociceptive properties and can be used as a potent analgesic. 3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate binds to the alpha1 adrenergic receptor and blocks the release of noradrenaline from nerve terminals in the brain. This prevents the activation of neurons in the spinal cord that transmit pain signals to the brain. The drug also inhibits the action of gamma aminobutyric acid on neurones and increases levels of cortisol concentration in blood plasma. The mechanism by which 3a,21 -dihydroxy 5a pregnane 11,20 dione 21 acetate produces its anaesthetic effects has not yet been elucidated.Formula:C23H34O5Purity:Min. 95%Molecular weight:390.51 g/molDecapreno-b-carotene
CAS:<p>Decapreno-b-carotene is a carotenoid extracted from the oil of the seeds of the plant, Schizochytrium limacinum. This product has been shown to be an effective antioxidant that can protect cells against oxidative damage. The high-performance liquid chromatography technique was used for quantification and separation. The extract was then injected onto a high performance liquid chromatograph, which separates it according to its chemical properties. Decapreno-b-carotene is found in almost all organisms and is a precursor for vitamin A production in animals.</p>Formula:C50H68Purity:Min. 95%Color and Shape:SolidMolecular weight:669.07 g/mol1,2-Dihydrobudesonide
CAS:<p>1,2-Dihydrobudesonide is a synthetic glucocorticosteroid that has a molecular structure similar to prednisolone. It is used for the treatment of inflammatory skin conditions such as eczema and psoriasis. 1,2-Dihydrobudesonide has been shown to have a high oral bioavailability and low systemic bioavailability. The molecule is metabolized in the liver to produce hydrocortisone, which accounts for its oral bioavailability. 1,2-Dihydrobudesonide is classified as an acetal because it contains an acetal linkage between the 16-carbon (C16) steroid nucleus and the 17-carbon (C17) side chain. This connection results in a more stable molecule than desonide, which is not acetalated. In vitro data indicates that 1,2-dihydrobudesonide has a lower binding affinity with human liver cytosolic receptors than des</p>Formula:C25H36O6Purity:Min. 95%Molecular weight:432.55 g/molδ9,11-Dehydro-17b-estradiol 17-valerate
CAS:Controlled ProductPlease enquire for more information about Delta9,11-Dehydro-17b-estradiol 17-valerate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C23H30O3Purity:Min. 96 Area-%Molecular weight:354.48 g/molall-trans-Retro retinol
CAS:<p>All-trans-retinol is a form of vitamin A that is found in many animal tissues and some plant oils. It acts as a hormone, binding to the retinoic acid receptors (RARs) in the nucleus and activating gene transcription. All-trans-retinol has been shown to be effective against hyperproliferative diseases such as cancer, both by inducing apoptosis and by inhibiting cell growth. All-trans-retinol may also have therapeutic potential for other diseases, such as intestinal cancers and prostatic hypertrophy. This compound has been shown to induce messenger RNA (mRNA) production in cells that express RARs.</p>Formula:C20H30OPurity:Min. 95%Molecular weight:286.45 g/mol2,2’,3,3’,4,4’,5,5’,6-Nonabromobiphenyl
CAS:Controlled Product<p>Please enquire for more information about 2,2’,3,3’,4,4’,5,5’,6-Nonabromobiphenyl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C12HBr9Purity:Min. 95%Molecular weight:864.27 g/mol3-(4'-Methoxy-3'-sulfonamidophenyl)-2-propylamine, hydrochloride
CAS:Controlled ProductPlease enquire for more information about 3-(4'-Methoxy-3'-sulfonamidophenyl)-2-propylamine, hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H16N2O3S•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:280.77 g/mol2,2'-Dipyridylamine
CAS:<p>2,2'-Dipyridylamine is a compound that belongs to the group of low-energy compounds. It has been shown to have antimicrobial activity against bacteria and fungi and has been demonstrated to be effective in treating cancer cells. 2,2'-Dipyridylamine is a molecule with two nitrogen atoms, which are bound by hydrogen bonds. This compound also contains methoxy groups that are coordinated by the nitrogen atoms. The structural analysis shows that there are three open coordination sites for metal ions that can bind with the nitrogen atoms. The x-ray diffraction data show that 2,2'-dipyridylamine crystallizes in a monoclinic system with an orthorhombic unit cell.</p>Formula:C10H9N3Purity:Min. 95%Molecular weight:171.2 g/mol4β-Hydroxy cholesterol 4-acetate
CAS:Controlled Product<p>4b-Hydoxy cholesterol 4-acetate is a pleiotropic drug with a wide range of pharmacological activities. It is an inhibitor of the sirtuin family of proteins and may have anti-cancer effects. It has also been shown to be effective in the treatment of depression and myelodysplastic syndrome. The mechanism of action for this agent is not well understood, but it may be due to its ability to inhibit DNA methyltransferases, which would lead to a change in DNA methylation patterns. 4b-Hydroxy cholesterol 4-acetate has also been shown to decrease lipid levels in the blood and increase the activity of liver enzymes that metabolize fatty acids. This drug can also modify lamellar bodies and short-chain fatty acids by inhibiting the enzyme ATP citrate lyase, which catalyzes citrate cleavage into acetyl CoA and oxaloacetate.</p>Formula:C29H48O3Purity:Min. 95%Molecular weight:444.69 g/molCodeine Impurity F
CAS:Controlled Product<p>Codeine Impurity F is a biochemical that is an impurity of codeine. Codeine Impurity F is a byproduct of the enzymatic reaction with morphine and the bacterial strain Pseudomonas putida. Codeine Impurity F has been shown to inhibit the growth of gram-negative bacteria, including Escherichia coli and Salmonella enterica, by binding to cellular membranes and inhibiting their function. It also binds to RNA in vitro and prevents translation of mRNA from its ribosome complex. The hydroxyl group on Codeine Impurity F binds to aluminium ions, which may interfere with the absorption of other drugs such as ampicillin or tetracycline. This impurity has been shown to have an effect on biological products such as immunoglobulins and albumin.</p>Formula:C18H21NO4Purity:Min. 95%Molecular weight:315.36 g/mol22α-Hydroxy cholesterol
CAS:Controlled Product<p>22a-Hydroxycholesterol is a naturally occurring, oxygenated cholesterol metabolite. It binds to the transcriptional coactivator retinoid X receptor (RXR) and inhibits the activity of certain liver enzymes. 22a-Hydroxycholesterol has been shown to have toxic effects on mouse tumors and to inhibit the production of ATP in vitro. 22a-Hydoxycholesterol also inhibits the function of ATP binding cassette (ABC) transporter proteins, which are involved in cholesterol transport from cells. The long-term toxicity of 22a-hydroxycholesterol is not well understood, although it has been shown that this metabolite can induce autoimmune diseases in rats.</p>Formula:C27H46O2Purity:Min. 95%Molecular weight:402.65 g/mol5,5'-Dinitro-2H,2'H-3,3'-bi-1,2,4-triazole
CAS:Controlled Product<p>Please enquire for more information about 5,5'-Dinitro-2H,2'H-3,3'-bi-1,2,4-triazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C4H2N8O4Purity:Min. 95%Molecular weight:226.11 g/mol(3β,5β,17α)-19-Norpregnane-3,17-diol
CAS:Controlled Product<p>Please enquire for more information about (3β,5β,17α)-19-Norpregnane-3,17-diol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C20H34O2Purity:Min. 95%Color and Shape:PowderMolecular weight:306.48 g/mol
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