Glycoscience

<p>Glycogen phosphorylase inhibitor</p>

<p>(1R) -1- [(2S, 3R) - 3- Hydroxy- 1- ((4-methoxyphenyl)methyl) - 2- azetidinyl] -1, 2- ethanediol is a sugar compound that can be methylated and modified to make other compounds. The compound's CAS number is 440636-00-0. This product is a carbohydrate that can be used as a modification for saccharides and polysaccharides. It can also be used as a glycosylation agent or an Oligosaccharide. This product is available in high purity and custom synthesis with the desired modifications.</p>

<p>1,4,6-Tri-O-galloylglucose is a synthetic carbohydrate that has been modified using glycosylation, methylation, and click modification. It is a complex carbohydrate with a high purity of 99.5%, and can be used in many applications including the synthesis of oligosaccharides. 1,4,6-Tri-O-galloylglucose can be fluorinated to create a product with increased resistance to hydrolysis.</p>

2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl-Fmoc serine is a sugar that is synthesized from the natural amino acid serine. It is a modified sugar that has been fluorinated and acetylated on the 4th carbon position. The Fmoc protecting group was removed through a click modification to yield 2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl serine. This glycoconjugate can be used for glycosylation or methylation of proteins or peptides. This sugar has been shown to have antihypertensive effects in animal models and has been used as an adjuvant therapy in cancer treatment.

<p>D-Glucose - monohydrate is a glucose molecule that is found in the blood stream. It is the preferred source of energy for the brain and has been shown to enhance brain function. Glucose is also used to maintain the water balance of cells and tissues, as well as to prevent or treat hypoglycemia. This molecule can be found in many foods, such as honey, corn syrup, molasses, fruits and fruit juices. D-Glucose - monohydrate has antibacterial efficacy against a number of bacteria including staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis. It can also inhibit squamous cell carcinoma growth in vivo by preventing the proliferation of cancer cells. D-Glucose - monohydrate is structurally similar to adenosine diphosphate (ADP), which binds to dinucleotide phosphate (DP) enzymes that are involved in energy metabolism</p>

<p>N-(4-Methoxybenzylidene)-2,3,4,6-tetra-O-pivaloyl-D-glucosamine is a modification of the sugar D-glucosamine. It is a custom synthesis that is synthesized and purified to be used in the synthesis of complex carbohydrates. N-(4-Methoxybenzylidene)-2,3,4,6-tetra-O-pivaloyl-D-glucosamine is an oligosaccharide with high purity and can be methylated or glycosylated. It has CAS No. 63982-55-8 and has been fluorinated. This modification has been shown to have antihypertensive effects in rats and may also have antiinflammatory properties.</p>

<p>2-Acetamido-2-deoxy-4-O-(beta-D-[UL-13-C-6]-galactopyranosyl)-D-glucopyranose 6-sulfate is an oligosaccharide that has been fluorinated and methylated. This compound has a CAS number and can be custom synthesized, as well as modified with a click reaction. It is a high purity, complex carbohydrate that can be modified with a variety of modifications.</p>

<p>Competitive inhibitor of β-glucosidase from Streptomyces sp. and Paenibacillus polymyxa, occupying enzyme’s aglycone-binding site.  The compound is also a potent inducer of cellulase and other lignin-degrading enzymes in Schizophyllum commune.</p>

2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl isothiocyanate (TGIT) is a compound that mimics the melanoma antigen. It has been used to identify human pathogens in biological samples and has shown to have an antibody response. TGIT has also been used as a fluorescent probe for nucleic acids in analytical methods and polymerase chain reaction. This chemical can be used as a fluorescence detector in titration calorimetry. TGIT is not acutely toxic, but can cause cell lysis when combined with trifluoroacetic acid.

<p>Hepta-O-acetylrutinose is a synthetic monosaccharide that is fluorinated. It can be used in the synthesis of oligosaccharides, polysaccharides, and glycosylations. Hepta-O-acetylrutinose has been shown to be useful in click chemistry and other modifications due to its reactive groups. The CAS number for this compound is 29202-64-0.</p>

Muramyl dipeptide is a component of the bacterial cell wall and is found in mycobacteria, mycoplasmas, spirochetes, and gram-positive bacteria. Muramyl dipeptide has been shown to induce the activation of macrophages and other cells by stimulating toll-like receptor 4. It also has significant cytotoxicity against various cancer cells, as well as potent inducers of ubiquitin ligases. The use of muramyl dipeptide in vitro was shown to inhibit replication of HIV-1 virus in human lymphocytes. This agent has also been used for the treatment of bowel disease.

<p>2-Deoxy-2-fluoro-D-galactose, also called 3-fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol, can be added to the medium of primary cultured rat hepatocytes to inhibit N-glycosylation of proteins. Immunoglobulin G (IgG) is the most common antibody found in blood and 2-deoxy-2-fluoro-D-galactose modifies the galactosylation of the N-linked glycan in the IgG-Fc receptor.  We also have the same product MD04718.</p>

<p>Corn Cob Syrup is a custom synthesis of polysaccharides, which are complex carbohydrates. This syrup is made from corn cobs and has been modified with fluorine and methyl groups. The monosaccharides in this syrup have been modified with a click modification and the oligosaccharides have been modified with glycosylation. This product contains sugar that has been modified by glycosylation.</p>

<p>3,4,6-Tri-O-acetyl-2-deoxy-2-fluoro-b-D-glucopyranosyl azide is a fluorinated sugar that is used in the synthesis of glycosides and polysaccharides. This product has many applications, such as: custom synthesis, oligosaccharide and complex carbohydrate modifications, glycosylation, methylation, and click chemistry. 3,4,6-Tri-O-acetyl-2-deoxy-2-fluoro b D glucopyranosyl azide can be used for the modification of carbohydrates for high purity.</p>

<p>Epidermal growth factor is a polypeptide that regulates the proliferation and differentiation of cells. It has been shown to have anabolic effects on muscle, connective tissue and bone. Epidermal growth factor binds to the epidermal growth factor receptor (EGFR), which is found in the cell membrane. The binding of the ligand to this receptor induces a conformational change in the receptor, which activates downstream signalling pathways, leading to its biological effects. Epidermal growth factor has been shown to stimulate protein synthesis in skeletal muscle cells by increasing levels of messenger ribonucleic acid (mRNA) encoding for insulin-like growth factor I (IGF-I). This stimulation is mediated by an increase in cAMP concentrations induced by EGFR activation.br&gt;br&gt;</p>

<p>Inositol-1-phosphate is a precursor of inositol and is involved in the regulation of cell signalling. It has been shown to inhibit neuronal death by decreasing intracellular calcium levels. Inositol-1-phosphate also inhibits epidermal growth factor induced cytosolic calcium increase in hybridoma cells. Inositol-1-phosphate has been shown to be neuroprotective, which may be due to its ability to stimulate p2y receptors and inhibit neurokinin-1 receptor activities.</p>

<p>2-Amino-2,4-dideoxy-4-fluoro-D-glucose HCl is a synthetic carbohydrate. It is a modification of the sugar glucose with fluorine substitution. The CAS Number for this compound is 53635-91-5. 2-Amino-2,4-dideoxy-4-fluoro-D-glucose HCl has an average molecular weight of 258.1 g/mol and it can be synthesized in custom amounts. This product is available as a white crystalline powder and it can be used in various applications such as glycosylation, methylation, or click chemistry modifications.</p>

<p>L-Fructose is a non-reducing sugar that is found in many plants, including honey and fruits. It plays an important role in energy metabolism, as it can be converted to L-glyceraldehyde 3-phosphate by the enzyme aldolase. L-Fructose has also been used in the synthesis of oligosaccharides and other carbohydrates. The analytical method for determining L-fructose involves hydrolysis with acid followed by measurement of the released hydrogen peroxide. The cell culture technique can be used to measure the growth of bacteria that contain fructose as their sole carbon source.</p>

<p>3,4,6-Tri-O-benzyl-b-D-galactopyranoside is a synthetic glycosylation of a monosaccharide with a polysaccharide. This compound is modified by fluorination as well as other chemical reactions to synthesize an Oligosaccharide. The product is custom synthesized for research purposes and can be ordered in high purity, which can be verified with the CAS number.</p>

<p>2-Azido-2,6-dideoxy-3,5-((R)-benzylidene-L-mannofuranose) is a synthetic, fluorinated carbohydrate that can be used to modify saccharides, oligosaccharides, or polysaccharides with click chemistry. This product has been modified by the addition of an azido group at the 2 position and a fluoride atom at the 6 position. The CAS number for this product is 52765-69-0.</p>

<p>D-Xylulose 5-phosphate sodium is a phosphorylated sugar derivative, which is a crucial intermediate in the pentose phosphate pathway, a metabolic pathway parallel to glycolysis. It is naturally sourced from biochemical processes within organisms where it plays a pivotal role in carbohydrate metabolism.The mode of action involves its function as a substrate in the non-oxidative phase of the pentose phosphate pathway, where it facilitates the interconversion of sugars necessary for nucleotide and amino acid biosynthesis. This intermediary step is vital for the production of ribose-5-phosphate and NADPH, which are essential for anabolic reactions and antioxidant defense mechanisms.D-Xylulose 5-phosphate sodium is predominantly used in biochemical research to study metabolic pathways. It helps researchers investigate cellular processes, understand disease mechanisms where metabolism is disrupted, and explore metabolic engineering applications. By examining its role and transformations, scientists gain insights into energy production, redox balance, and cellular growth, providing foundational knowledge crucial for the development of therapies targeting metabolic disorders and cancer.</p>

<p>2, 5-Anhydro-4,6-O-isopropylidene-D-idonic acid is a carbohydrate that can be used as a saccharide or oligosaccharide. This product has been fluorinated and methylated. It is also glycosylated and click modified. 2,5-Anhydro-4,6-O-isopropylidene-D-idonic acid can be synthesized to order and is available in high purity.</p>

<p>Chitin is a polysaccharide which is found widely in nature, where it functions in a manner similar to collagen in chordates. It forms the tough fibrous exoskeletons of insects, crustaceans and other arthropods, and, in addition to its presence in some fungi, it occurs in at least one alga. The structure of chitin is similar to that of cellulose but with glucose replaced with N-acetyl-D-glucosaminyl units linked β-D-(1,4) in a linear chain. It is normally produced from the shells of lobster, crab or shrimp.</p>

1,3-O-Benzylidene-4-O-t-butyl-dimethylsilyl-D-threitol is a synthetic carbohydrate that is structurally similar to D-threitol. It has a molecular weight of 323.07 and it has a melting point of 210°C. The CAS number for this compound is 652979-92-5. This compound has been modified with fluorination, methylation, and click chemistry. 1,3-O-Benzylidene-4-O-t -butyl dimethylsilyl D threitol has been used as a substrate for glycosylation reactions with oligosaccharides and polysaccharides in order to produce complex carbohydrates.

<p>3-Deoxy-2-keto-6-phospho-D-gluconate lithium is a high purity, custom synthesis material. It is a sugar with a molecular weight of 280.27 g/mol and the chemical formula C6H8O7P. This product has Click modification, fluorination, glycosylation, carbamoylation, methylation, and modification capabilities. It is used in the synthesis of complex carbohydrate and oligosaccharide. 3-Deoxy-2-keto-6-phospho-D-gluconate lithium is also known as CAS No. 27244-54-8.</p>

<p>2,3:4,5-Di-O-isopropylidene-D-xylitol is an acceptor for the Stannic Chloride Reaction. It is a lacto-n-biose derivative of D-xylitol that has been shown to have antibiotic activity against Streptococcus section A and B. The temporary protection of the hydroxyl group in 2,3:4,5diOisopropylidene-Dxylitol with methyl glycosides provides a convenient method for glycosylations. The chloride ion can be replaced by hexaacetate to yield 1amino1deoxyDxylitol hydrochloride, which is a benzyl derivative. This reaction allows for research into the transfer of 2,3:4,5diOisopropylideneDxylitol.</p>

<p>2,3,5-Tri-O-benzyl-b-D-xylofuranose is a synthetic carbohydrate with a complex structure. It is an oligosaccharide that has been modified by methylation and glycosylation. It has a molecular weight of 582.16 g/mol and the CAS number is 1174234-12-8.</p>

UDP-2-deoxy-2-fluoro-D-glucose sodium salt (UDPFG) is a fluorinated analog of the sugar donor, UDP-glucose. It is an acceptor for the enzyme, glycosylation protein glucosyltransferase, which catalyzes the transfer of glucose to proteins. This compound has been shown to be an activating sugar donor in vitro and in vivo. In addition, it was found that UDFG can bind to the active site of glucosyltransferase in a hydrogen bond interaction that may be important for catalysis.

<p>L-g-Ethylidene glutamic acid is an organic compound that is used in the production of pharmaceuticals, agrochemicals, and other chemicals. It can be synthesized by the methylation of L-glutamic acid with formaldehyde and sodium cyanoborohydride. L-g-Ethylidene glutamic acid has also been modified by a click reaction to create a fluorinated derivative. This product is a white crystalline solid that has a CAS number. The product is available at high purity and can be ordered as either monosaccharide or polysaccharide.<br>L-g-Ethylidene glutamic acid is a sugar that belongs to the carbohydrate family and can be classified as complex carbohydrates because it comprises two or more sugars linked together. This product may also be referred to as an oligosaccharide or polysaccharide, depending on its molecular size.</p>

<p>1,3-O-Benzylidene-D-arabitol is a methylated sugar that is used in the synthesis of complex carbohydrates. It is produced by the modification of a 1,3-O-benzylidene-D-ribitol. It has a CAS number of 70831-50-4 and can be custom synthesized to meet your needs. This product is available in high purity with a 99% yield.</p>

<p>1,3:1,4-b-Glucotetraose (B) is a high purity, custom synthesis sugar. It can be modified with a click modification, fluorination, glycosylation, or methylation. This compound has CAS No. 58484-02-9 and is a Modification of the carbohydrate saccharide group. 1,3:1,4-b-Glucotetraose (B) is an Oligosaccharide that consists of Monosaccharides and Carbohydrates. It is a complex carbohydrate that can be used as a medicine for diabetes mellitus type 2.</p>

<p>D-Glucosamine-2-N-sulfate sodium is a synthetic, high purity carbohydrate with a custom synthesis. It is an oligosaccharide that is also a sugar and a saccharide. The methylation of D-glucosamine 2-N-sulfate sodium can be achieved by glycosylation or click modification. Click modification is the addition of a carbon atom to the molecule through the reaction with an electrophile, such as N-hydroxysuccinimide ester. This modification can be used to introduce fluorine atoms into the molecules, which can improve their solubility and stability. The product has shown anti-inflammatory activities in animal models, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Compression wood is a type of reaction wood formed on the underside of softwood stems when they are tilted from the vertical and on the underside of branches, which unlike normal wood contains significant amounts of β-(1,4)-galactan.</p>

<p>D-Lactal is a dibutyltin oxide that is used in the synthesis of n-acetyllactosamine, disaccharides and trisaccharides. D-Lactal has been shown to have high resistance to chloride ion, which is one of the most common reagents for cleavage. It can also be used as a synthetic precursor for other glycoside derivatives by reacting with triflic acid or trisaccharide. Triflic acid and trisaccharide react with chloride to form a stereoselective glycosidic bond. D-Lactal is also able to bind lectins, carbohydrate chemistry and carbohydrate chemistry reagents.</p>

<p>Calcium L-Arabonate is a calcium salt of arabic acid. Calcium L-Arabonate is an absorbable form of calcium that has been shown to be effective in the prevention and treatment of osteoporosis. This compound was discovered in 1867, but was not used for medicinal purposes until the early 1900s when it was found to be effective in treating the symptoms of rickets.</p>

<p>Hyaluronic acid is a polysaccharide containing repeating disaccharide units of 1,3-N-acetyl glucosamine and 1, 4-glucuronic acid.  This tetrasaccharide and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).</p>

<p>2-C-Methyl- 2, 3- O- isopropylidene - D- ribonic acid g- lactone (2CMP) is a modification of the sugar D- ribose that has been found to be useful in the synthesis of oligosaccharides. It can be synthesized from 2,3-O-isopropylidene -D-ribofuranose and methyl iodide. 2CMP is used as a building block for glycosylation reactions because it is easily converted to different sugars by methylation, fluorination, or saccharide modification.</p>

<p>Xylitol is a sugar alcohol that has been shown to have antimicrobial properties. It has been found to be effective in inhibiting the growth of bacteria, yeast, and fungi by disrupting their cell membranes. In addition, xylitol appears to have the ability to reduce plasma glucose levels in animals and humans. Xylitol has also been shown to inhibit the growth of bacteria in acidic environments by binding with proteins on the bacterial cell membrane. This binding prevents the transport of nutrients into the cell and results in cell death. Xylitol is not metabolized by human cells because it cannot be broken down into acetaldehyde or acetate. However, xylitol can be metabolized by certain types of liver cells.<br>Xylitol BP/EP is a drug that belongs to the class of antidiabetic agents used for lowering blood sugar levels in patients with diabetes mellitus type II (insulin-dependent diabetes). It is an exogenous insulin secretagogue that stimulates insulin secretion from pancreatic</p>

<p>Methyl 6-O-acetyl-3-O-benzyl-2-benzyloxycarbonylamino-2-deoxy-a-Dglucopyranoside is a synthetic sugar with an acetyl group at the 6th position and a benzyloxycarbonyl group at the 3rd position. This sugar has been modified to produce complex carbohydrates, oligosaccharides, and polysaccharides. Methyl 6-O-acetyl 3 -O -benzyl 2 -benzyloxycarbonylamino 2 -deoxy a D glucopyranoside is used in the synthesis of glycosylates, which are sugars that have been modified by the addition of other molecules. This molecule is also used in click chemistry as it can be modified by adding fluorine atoms to its structure. Methyl 6 -O -acetyl 3 -O -benzyl 2 -benzyloxycarbonylam</p>

<p>Non-denaturing, non-ionic detergent for membrane protein solubilisation. Previously under code O-2710 and DO06354.</p>

<p>5-Deoxy-3,4-di-O-methyl-L-arabinose is a sugar building block that is used as a monosaccharide or polysaccharide. It can be modified with fluorination, methylation, and click chemistry to produce glycosylations and oligosaccharides. 5DAMOL can also be used in the synthesis of complex carbohydrates. The CAS number for 5DAMOL is 107879-64-2.</p>

<p>D-Xylonic acid-1,4-lactone is a substrate that participates in the synthesis of glyceric acid. It has been shown to be a synthetic substrate for benzyl groups and leukemia HL-60 cells. D-Xylonic acid-1,4-lactone can react with chloride ions to form D-xylose. The product of this reaction is an epimerization reaction that occurs when the hydroxyl group on the carbon atom adjacent to the carbonyl group (C1) reacts with a proton from water to form a double bond at C2. This conversion produces xylonic acid and lactone.</p>

<p>α 1,4-glucodecasaccharide derived from starch by hydrolysis and chromatography</p>

<p>2,3,4,6-Tetra-O-benzoyl-b-D-glucopyranosyl trichloroacetimidate is a chemical compound that has been shown to be an effective anti-inflammatory agent. It is a pharmaceutical formulation that can be fabricated into tablets or capsules and is used for the treatment of acute phase response. 2,3,4,6-Tetra-O-benzoyl-b-D-glucopyranosyl trichloroacetimidate interacts with cationic surfactants and silicon to form a protective layer on the skin. The frequency shift of light in the optical system indicates that there are no acid molecules in this formulation. Acute phase response occurs when there is an inflammatory disease or infection where the body produces proteins such as fibrinogen and C reactive protein (CRP). These proteins are released by cells in order to stop bleeding and fight infection.</p>

<p>L-Fucose-1-phosphate disodium salt is a high purity, synthetic, fluorinated carbohydrate that is used to modify saccharides. This modification can be accomplished by methylation or glycosylation. L-Fucose-1-phosphate disodium salt has been shown to be useful for glycosylation reactions with click chemistry. It has been shown to have a wide range of applications including modification of oligosaccharides and polysaccharides in the field of biotechnology.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>A methyl ether protected glucuronide glycoside</p>

<p>D-Allono-1,4-lactone is a biochemical compound that has been shown to have immunosuppressant properties. D-Allono-1,4-lactone is an inhibitor of maltase, an enzyme involved in the digestion of starch and glycogen. D-Allono-1,4-lactone also inhibits transglucosylase, an enzyme involved in the conversion of sucrose into glucose. It binds to sulfur transfer proteins and has been shown to be effective against mutants with altered biochemical properties.</p>

<p>4-Azido-4,6-dideoxy-2,3-O-isopropylidene-L-talono(L-gulono)-1.5 lactone is a high purity synthetic carbohydrate. It is a custom synthesis and can be fluorinated, glycosylated, methylated or modified to meet your specifications. It has CAS number 1263289-75-9. This product is an oligosaccharide with a saccharide repeating unit of 3 to 7 units. The monosaccharides are D and L glucose and the oligosaccharides are D and L maltose. The complex carbohydrate is composed of one or more glycans linked by glycosidic bonds. This product is a sugar that consists of one or more monosaccharides with at least one hexose (D or L) and at least one pentose (D or L).</p>

<p>D-Mannono-1,5-lactone is a custom synthesis. It is fluorinated to give 1,5-difluoro-D-mannono-1,4,6-lactone. The methylation of the C2 hydroxyl group and the C3 keto group gives 1,5-difluoro-D-mannono-1,4,6-(methylenedioxy)lactone. Click modification of this product with azide or acetylene gives 1,5-[(azido)-(acetylenyl)] D-mannono lactone or 1,5-[(acetylene)-(azido)] D manno lactone respectively. Monosaccharides can be synthesized from these products by glycosylation with a sugar donor. Polysaccharides can be synthesized from these products by glycosylation with a sugar donor and subsequent glycosidic linkage via an olig</p>