Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 835 products of "Antifungals"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
(R)-(-)-2-Oxothiazolidine-4-carboxylic Acid
CAS:Controlled ProductFormula:C4H5NO3SColor and Shape:NeatMolecular weight:147.15Gibberellin A7 Methyl Ester
CAS:Controlled ProductFormula:C20H24O5Color and Shape:NeatMolecular weight:344.42-(1-(Allyloxy)-2-(1H-imidazol-1-yl)ethyl)-3,5-dichlorophenol
Controlled ProductFormula:C14H14Cl2N2O2Color and Shape:NeatMolecular weight:313.1795-Fluoro-2-mercaptobenzothiazole
CAS:Controlled Product<p>Applications 5-Fluoro-2-mercaptobenzothiazole is used as a reagent in the synthesis of [[(benzothiazolyl)thio]methyl]phenyl]furanone derivatives with agrochemical fungicidal activities.<br>References Zhao, P., et al.: Youji Huaxue, 30, 1567 (2010);<br></p>Formula:C7H4FNS2Color and Shape:NeatMolecular weight:185.24TH-302
CAS:Controlled Product<p>Applications TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell<br>References Meng, F. et al.: Mol. Cancer Ther., 11, 740 (2012); Liu, Q. et al.: Cancer Chemother. Pharmacol., 69, 1487 (2012); Sun, J.D. et al.: Clin. Cancer Res., 18, 758 (2012);<br></p>Formula:C9H16Br2N5O4PColor and Shape:NeatMolecular weight:449.04α-Butylpiperonyl Alcohol
CAS:Controlled Product<p>Applications Intermediate in the preparation of insecticides, fungicides, and other pesticides.<br>References Wilkinson, C., et al.: J. Agric. Food Chem., 14, 73 (1966), Zhong, W., et al.: J. Chem. Res., 6, 370 (2009),<br></p>Formula:C12H16O3Color and Shape:NeatMolecular weight:208.25cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Controlled Product<p>Applications cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol is an impurity in the synthesis of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazol.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)<br></p>Formula:C13H13Cl2N3O3Color and Shape:NeatMolecular weight:330.171-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole
CAS:Controlled Product<p>Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Formula:C16H12ClN3O3Color and Shape:NeatMolecular weight:329.74Nitrefazole
CAS:Controlled Product<p>Applications Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Klink, R. et al.: Arzneimittelforschung., 35, 1220 (1985); Koda L. et al.: Life Sci., 35, 1659 (1984);<br></p>Formula:C10H8N4O4Color and Shape:Light Yellow To YellowMolecular weight:248.195-Mercapto-1H-1,2,3-triazole Sodium Salt
CAS:Controlled Product<p>Applications 5-Mercapto-1H-1,2,3-triazole Sodium Salt is used as a reactant in the preparation of cephem derivatives as anti-Helicobacter pylori agents in relation to lability towards β-lactamase and potential for causing diarrhea.<br>References Yoshida, Y., et al.: Bioorg. Med. Chem., 8, 2317 (2000);<br></p>Formula:C2H2N3NaSColor and Shape:NeatMolecular weight:123.111-Methyl-4-nitroimidazole
CAS:Controlled Product<p>Applications 1-Methyl-4-nitroimidazole is a moiety of Azathioprine (A803350) and is predicted to have mutagenic potential.<br>References Rosenkranz, H. S., et al.: Mutat. Res-Fund. Mol. M., 251, 157 (1991); Kelly, G. E., et al.: Photochem. Photobiol., 49, 59 (1989)<br></p>Formula:C4H5N3O2Color and Shape:White To Light YellowMolecular weight:127.12-Methylbenzothiazole-6-carboxylic Acid (~90%)
CAS:Controlled Product<p>Applications 2-Methylbenzothiazole-6-carboxylic Acid (~90%) is a useful research chemical, a reagent for the synthetic studies on fungicidal agents.<br>References Saikachi, H., et al.: Yakugaku Zasshi, 78, 376 (1958); Bosco, M., et al.: Annali di Chimica, 58, 1148 (1968)<br></p>Formula:C9H7NO2SPurity:~90%Color and Shape:NeatMolecular weight:193.22(AlphaE)-2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester
CAS:Controlled Product<p>Applications (αE)-2-[(6-chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester is an intermediate in the synthesis of Azoxystrobin (A965150), an strobilurin fungicide.<br></p>Formula:C15H13ClN2O4Color and Shape:NeatMolecular weight:320.73[1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol
Controlled Product<p>Applications [1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol is an intermediate in synthesizing 2-Biphenylyl Sulfate-d5 Potassium Salt (B397897), which is the isotope labelled analog of 2-Biphenylyl Sulfate Potassium Salt. 2-Biphenylyl Sulfate Potassium Salt is a derivative of 2-Phenylphenol (P335870). 2-Phenylphenol is a agriculture fungicide and is no longer used as a food additive.<br>References Scheuhly, W., et al.: Chem. Biol., 18, 1053 (2011); Singh, H.P., et al.: Food. Chem. Toxicol., 48, 1040 (2010); Gouin, T., et al.: Envro. Pollu., 165, 208 (2012);<br></p>Formula:C41H32N2OColor and Shape:NeatMolecular weight:568.706Levofloxacin
CAS:<p>Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.</p>Formula:C18H20FN3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:361.37 g/molBeauvericin
CAS:<p>Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.</p>Formula:C45H57N3O9Purity:Min. 95%Molecular weight:783.95 g/mol2-Methyl-4-isothiazolin-3-one
CAS:Controlled Product<p>2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.</p>Formula:C4H5NOSPurity:Min. 96%Color and Shape:Yellow PowderMolecular weight:115.15 g/molAureothin
CAS:<p>Aureothin is a bioactive compound, classified as a polyketide antibiotic, which is derived from the culture of the bacterium Streptomyces thioluteus. This compound operates primarily through the inhibition of protein synthesis by interfering with the aminoacylation of tRNA with specific amino acids. Its mode of action disrupts cellular protein synthesis, which is essential for cell growth and function, leading to its potent antibacterial and antifungal activities.</p>Formula:C22H23NO6Purity:Min. 95%Color and Shape:PowderMolecular weight:397.42 g/molCaerulomycin A
CAS:<p>Caerulomycin A is a bioactive compound classified as a natural broad-spectrum antibiotic, which is derived from various Streptomyces species found in soil. Its mode of action involves inhibiting fungal and bacterial growth by interfering with essential cellular processes, effectively curbing the proliferation of pathogenic microorganisms. This potent molecule achieves its effects by binding to specific cellular targets, thereby disrupting cell wall synthesis and other critical metabolic pathways.</p>Formula:C12H11N3O2Purity:Min. 95%Molecular weight:229.23 g/molSordarin sodium salt
CAS:<p>Sordarin sodium salt is an antifungal agent, characterized as a semisynthetic derivative produced from the fermentation products of filamentous fungi, specifically belonging to the phylum Ascomycota. This compound exerts its effects by selectively inhibiting fungal protein synthesis. It achieves this by obstructing the function of elongation factor 2 (EF-2), an essential component of fungal ribosomal activity, thereby disrupting the translational elongation step of protein synthesis.</p>Formula:C27H39NaO8Purity:Min. 95%Molecular weight:514.58 g/molFilipin III
CAS:<p>Filipin III is a polyene macrolide antibiotic, which is extracted from Streptomyces filipinensis. Known for its unique mode of action, Filipin III interferes with cholesterol-rich membranes by binding to ergosterol and cholesterol. This interaction disrupts the membrane structure, altering membrane permeability and ultimately affecting cell viability.</p>Purity:Min. 95%Naftifine N-Oxide
CAS:<p>Naftifine N-Oxide is an antifungal agent, which is derived from synthetic chemical processes. Its structure is based on the modification of the known antifungal, naftifine, by introducing an N-oxide functional group, which may enhance certain pharmacokinetic properties. As a synthetic derivative, Naftifine N-Oxide is specifically designed to interfere with the biosynthesis of ergosterol, an essential component of fungal cell membranes. By inhibiting squalene epoxidase, an enzyme crucial to the ergosterol pathway, Naftifine N-Oxide effectively disrupts the development and maintenance of the fungal cell membrane, compromising cell integrity and leading to antifungal activity.</p>Formula:C21H21NOPurity:Min. 95%Molecular weight:303.4 g/molNeoaureothin
CAS:<p>Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics.</p>Formula:C28H31NO6Purity:Min. 95%Molecular weight:477.5 g/mol21-Norrapamycin
CAS:<p>21-Norrapamycin is a macrocyclic lactone antibiotic, which is derived from the bacterium Streptomyces hygroscopicus. Its chemical structure is closely related to that of rapamycin, a well-known immunosuppressant. The mode of action of 21-Norrapamycin involves the inhibition of the mechanistic target of rapamycin (mTOR) signaling pathway. By binding to the FK506-binding protein 12 (FKBP12), it forms a complex that then inhibits mTOR, a crucial regulator of cell growth, proliferation, and survival.</p>Formula:C50H77NO13Purity:Min. 95%Molecular weight:900.1 g/molZelkovamycin
CAS:<p>Zelkovamycin is a novel antibacterial compound isolated from endophytic microorganisms, specifically Streptomyces sp. Endophytes are bacteria or fungi that reside within plant tissues, forming symbiotic relationships and often producing bioactive metabolites. The mode of action of Zelkovamycin involves the inhibition of bacterial cell wall synthesis, interfering with the biosynthesis pathways essential for maintaining the structural integrity and function of bacterial cell walls, particularly in Gram-positive strains.</p>Formula:C36H45N9O9SPurity:Min. 95%Color and Shape:PowderMolecular weight:779.86 g/molPropiconazole
CAS:<p>Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.</p>Formula:C15H17Cl2N3O2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:342.22 g/molMalformin C
CAS:<p>Malformin C is a cyclic pentapeptide, which is a secondary metabolite derived from certain strains of the fungus Aspergillus. Its mode of action involves disrupting cellular processes by interfering with cell division. Specifically, it is thought to affect mitotic spindle formation, leading to abnormal cell cycle progression.</p>Formula:C23H39N5O5S2Purity:Min. 95%Color and Shape:PowderMolecular weight:529.72 g/molMiconazole
CAS:<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>Formula:C18H14Cl4N2OPurity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:416.13 g/mol41-Oxo-rapamycin
CAS:<p>41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.</p>Formula:C51H77NO13Purity:Min. 95%Molecular weight:912.2 g/molHexamide
CAS:<p>Hexamide is a protein inhibitor.</p>Formula:C13H17NOColor and Shape:SolidMolecular weight:203.28SSF-109
CAS:<p>SSF-109 is a broad-spectrum fungicide, has protective activity against plant disease.</p>Formula:C15H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:291.78Kayahope
CAS:<p>Kayahope is a novel antifungals.</p>Formula:C15H14ClNO3SPurity:98%Color and Shape:SolidMolecular weight:323.79Fenhexamid
CAS:<p>Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus.</p>Formula:C14H17Cl2NO2Purity:99.56%Color and Shape:SolidMolecular weight:302.20Fosravuconazole
CAS:<p>Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.</p>Formula:C23H20F2N5O5PSPurity:98%Color and Shape:SolidMolecular weight:547.47Prochloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Formula:C15H16Cl3N3O2Purity:99.75% - 99.79%Color and Shape:Colorless SolidMolecular weight:376.67Antifungal agent 67
CAS:<p>Compound 9 (Antifungal agent 67), an imidazole class antifungal, exhibits efficacy against Candida and possesses a CC50 value of 33.6 μM in neonatal rat</p>Formula:C23H25ClN2O3Color and Shape:SolidMolecular weight:412.91Fuberidazole
CAS:<p>Fuberidazole is an antifungal agent.</p>Formula:C11H8N2OPurity:98.95%Molecular weight:184.19Silthiofam
CAS:<p>Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.</p>Formula:C13H21NOSSiPurity:98%Color and Shape:SolidMolecular weight:267.46Fungicide4
CAS:<p>Fungicide4 exhibits the high activity against the P. infestans strain.</p>Formula:C14H11N3OColor and Shape:SolidMolecular weight:237.26Chitin synthase inhibitor 10
CAS:<p>Chitin Synthase Inhibitor 10: potent antifungal with 0.11 mM IC50, effective against resistant C. albicans and C. neoformans. Used in IFI research.</p>Formula:C24H23Br2N3O6Color and Shape:SolidMolecular weight:609.26Isobellidifolin
CAS:<p>Isobellidifolin, a xanthone compound, serves as a free radical scavenger and antioxidant. It exhibits a potent antifungal effect.</p>Formula:C14H10O6Color and Shape:SolidMolecular weight:274.23Cercosporamide
CAS:<p>Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.</p>Formula:C16H13NO7Purity:98%Color and Shape:SolidMolecular weight:331.289-OxoOTrE
CAS:<p>9-OxoOTrE, made by oxidizing 9-HpOTrE, has antimicrobial effects on plant pathogens like bacteria and fungi.</p>Formula:C18H28O3Color and Shape:SolidMolecular weight:292.41BHBM
CAS:<p>BHBM, an acylhydrazone antifungal, halts C. neoformans growth (MIC80 = 1 μg/ml) by blocking glucosylceramide synthesis.</p>Formula:C15H13BrN2O2Color and Shape:SolidMolecular weight:333.18Ametoctradin
CAS:<p>Ametoctradin is a Qo-site inhibitor of mitochondrial respiratory complex III and is used in the study of oomycete diseases.</p>Formula:C15H25N5Purity:99.65%Color and Shape:SolidMolecular weight:275.39NB-598 hydrochloride
CAS:<p>NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.</p>Formula:C27H32ClNOS2Purity:98%Color and Shape:SolidMolecular weight:486.13Antifungal agent 33
CAS:<p>Antifungal 33 (4e) strongly inhibits Candida albicans. MIC: 16 μg/ml; IC50: 0.19 μg/ml.</p>Formula:C21H14ClN5O3Color and Shape:SolidMolecular weight:419.82Antifungal agent 22
CAS:<p>Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.</p>Formula:C21H26Cl3NOSColor and Shape:SolidMolecular weight:446.86P163-0892
CAS:<p>P163-0892: potent, specific antifungal for Cryptococcus; moderate blood-brain barrier penetration.</p>Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:356.44
![1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC877880.webp&w=3840&q=75)
![(AlphaE)-2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC380240.webp&w=3840&q=75)
![[1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB398705.webp&w=3840&q=75)
