Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 908 products of "Antifungals"
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Byssochlamic Acid
CAS:Byssochlamic acid, a mycotoxin identified in the agricultural fungal pathogen B. fulva, exhibits lethality in mice with an LD50 of 94 mg/kg.Formula:C18H20O6Color and Shape:SolidMolecular weight:332.4Antifungal agent 50
CAS:Antifungal agent 50 exhibits minimum inhibitory concentrations (MICs) ranging from less than 0.063 to 1 μg/mL [1].Formula:C25H20ClN5O2SColor and Shape:SolidMolecular weight:489.98Eucalyptacid A
CAS:Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)Formula:C17H32O5Color and Shape:SolidMolecular weight:316.43FR194738 free base
CAS:FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.Formula:C27H37NO2SPurity:99.13%Color and Shape:SolidMolecular weight:439.65Ref: TM-T11321
1mg75.00€5mg164.00€1mL*10mM (DMSO)177.00€10mg234.00€25mg353.00€50mg487.00€100mg637.00€Fenpropidin
CAS:Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.Formula:C19H31NPurity:98.58% - 99.54%Color and Shape:SolidMolecular weight:273.46Inz-1
CAS:Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.Formula:C16H14N2O2Purity:99.55% - 99.88%Color and Shape:SolidMolecular weight:266.29Methyl 3,4-dimethoxycinnamate
CAS:Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].Formula:C12H14O4Color and Shape:SolidMolecular weight:222.24Antifungal agent 77
CAS:Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, HelicoverpaFormula:C21H18FN5O2Color and Shape:SolidMolecular weight:391.4N,O-Diacetyltyramine
CAS:N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].Formula:C12H15NO3Color and Shape:SolidMolecular weight:221.25Phenamacril
CAS:Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.Formula:C12H12N2O2Purity:99.52%Color and Shape:SolidMolecular weight:216.24Ref: TM-T24214
1mg138.00€1mL*10mM (DMSO)259.00€5mg303.00€10mg447.00€25mg713.00€50mg1,018.00€100mg1,369.00€500mg2,673.00€Antifungal agent 24
CAS:Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).Formula:C24H18F2N4OColor and Shape:SolidMolecular weight:416.42Laxifloran
CAS:Laxifloran possesses antibacterial and antifungal properties.Formula:C17H18O5Color and Shape:SolidMolecular weight:302.322-Dodecanol
CAS:2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].Formula:C12H26OColor and Shape:SolidMolecular weight:186.33Antiproliferative agent-33
CAS:Antiproliferative Agent-33 (Compound 2g) serves as an anti-proliferative, antifungal, and antibacterial agent, effectively inhibiting the proliferation of MDA-Formula:C21H26N2OColor and Shape:SolidMolecular weight:322.44TMTD (Tetramethylthiuram disulfide)
CAS:TMTD (Tetramethylthiuram disulfide) reduces the growth performance of chickens by reducing liver index, while increasing kidney, heart and spleen index. In addition, TMTD also induces tibial chondrodysplasia (TD) by regulating the expression of VEGF, HIF-1α and WNT4. As a super accelerator in rubber processing, TMTD plays an important role in the low-temperature vulcanization process and is a key pesticide in agriculture.Formula:C6H12N2S4Color and Shape:SolidMolecular weight:240.43Azaconazole
CAS:Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust.Formula:C12H11Cl2N3O2Color and Shape:SolidMolecular weight:300.144′-DTMP
CAS:4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.Formula:C13H16N4O3Purity:98%Color and Shape:SolidMolecular weight:276.29TMV-IN-5
CAS:TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by bindingFormula:C22H23N3SColor and Shape:SolidMolecular weight:361.5Alteconazole
CAS:Alteconazole is an antifungal drug.Formula:C17H12Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:380.66Prochloraz manganese
CAS:Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.Formula:C60H64Cl14MnN12O8Color and Shape:SolidMolecular weight:1632.51MoTPS1-IN-1
CAS:MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.Formula:C23H27F3N2O4Purity:99.76%Color and Shape:SoildMolecular weight:452.47Zoxamide
CAS:Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [Formula:C14H16Cl3NO2Color and Shape:SolidMolecular weight:336.64Inz-5
CAS:Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.Formula:C18H14F4N6Color and Shape:SolidMolecular weight:390.342,4′-Dichloroacetanilide
CAS:2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.Formula:C8H7Cl2NOPurity:99.36%Color and Shape:SolidMolecular weight:204.05Fengycin
CAS:Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.Formula:C72H110N12O20Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:1,463.71 g/molEconazole
CAS:Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.Formula:C18H15Cl3N2OPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:381.68 g/molAntifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Formula:C24H26N4Se2Color and Shape:SolidMolecular weight:528.41Antifungal agent 125
CAS:Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.Formula:C13H10BrNO4SColor and Shape:SolidMolecular weight:356.192CDA-IN-2
CAS:CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.Formula:C17H16N2O7Color and Shape:SolidMolecular weight:360.318Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formula:C17H20ClN3O2Purity:98%Color and Shape:SolidMolecular weight:333.81N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Formula:C11H9FN4OColor and Shape:SolidMolecular weight:232.21A25822B
CAS:A25822B is an antifungal agent.Formula:C28H45NOPurity:98%Color and Shape:SolidMolecular weight:411.66Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Formula:C22H20Cl2N4SeColor and Shape:SolidMolecular weight:490.29Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Formula:C24H24N4O8Color and Shape:SolidMolecular weight:496.47Yck2-IN-1
CAS:Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.Formula:C19H11FN4Color and Shape:SolidMolecular weight:314.316Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Formula:C21H23NO5Color and Shape:SolidMolecular weight:369.41SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formula:C30H37Cl2N5O3Color and Shape:SolidMolecular weight:586.55Fosmanogepix
CAS:Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.Formula:C22H21N4O6PPurity:98%Color and Shape:SolidMolecular weight:468.40Antifungal agent 100
CAS:Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].Formula:C23H21N3O4SColor and Shape:SolidMolecular weight:435.5Succinate dehydrogenase-IN-8
CAS:Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).Formula:C22H19Cl2F2N5O2Color and Shape:SolidMolecular weight:494.32Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Formula:C12H10N4SColor and Shape:SolidMolecular weight:242.3Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Formula:C27H21N5O2SColor and Shape:SolidMolecular weight:479.55WQ3810 TFA
WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity ofFormula:C24H23F6N5O5Purity:99.52%Color and Shape:SoildMolecular weight:575.46Antifungal agent 28
Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.Formula:C22H29N5OSColor and Shape:SolidMolecular weight:411.56Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Formula:C19H18F4O2Color and Shape:SolidMolecular weight:354.34Nikkomycin Z
CAS:Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,Formula:C20H25N5O10Purity:98%Color and Shape:SolidMolecular weight:495.44PKR-IN-1
CAS:PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).Formula:C9HCl5N4OS2Color and Shape:SolidMolecular weight:422.525Hyalodendrin
CAS:Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.Formula:C14H16N2O3S2Color and Shape:SolidMolecular weight:324.42CDA-IN-4
CAS:CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.Formula:C10H9BrN4O2SColor and Shape:SolidMolecular weight:329.17Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formula:C21H19F2N7O3S2Color and Shape:SolidMolecular weight:519.55
