Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 835 products of "Antifungals"
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Verazine
CAS:<p>(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral</p>Formula:C27H43NOColor and Shape:SolidMolecular weight:397.642-Dodecanol
CAS:<p>2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].</p>Formula:C12H26OColor and Shape:SolidMolecular weight:186.33Antifungal agent 49
CAS:<p>Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].</p>Formula:C15H12O4Color and Shape:SolidMolecular weight:256.25APX2039
CAS:<p>APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity</p>Formula:C20H15FN4O2Purity:98.72% - 99.07%Color and Shape:SolidMolecular weight:362.36Fenpropidin
CAS:<p>Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.</p>Formula:C19H31NPurity:98.58% - 99.54%Color and Shape:SolidMolecular weight:273.46Y18501
CAS:<p>Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.</p>Formula:C27H26F2N6O2SColor and Shape:SolidMolecular weight:536.6Dihydroaltenuene B
CAS:<p>Dihydroaltenuene B inhibits mushroom tyrosinase (IC50: 38.33µM) and binds His244, Met280, Gly281 via hydrogen bonds.</p>Formula:C15H18O6Color and Shape:SolidMolecular weight:294.3HDAC/HSP90-IN-3
CAS:<p>HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.</p>Formula:C26H33N5O6Color and Shape:SolidMolecular weight:511.57Antiproliferative agent-18
CAS:<p>Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].</p>Formula:C26H27FN2OSColor and Shape:SolidMolecular weight:434.57Antifungal agent 77
CAS:<p>Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, Helicoverpa</p>Formula:C21H18FN5O2Color and Shape:SolidMolecular weight:391.4Chitin synthase inhibitor 14
CAS:<p>Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant</p>Formula:C25H26ClN5O5Color and Shape:SolidMolecular weight:511.96Orysastrobin
CAS:<p>Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheath</p>Formula:C18H25N5O5Color and Shape:SolidMolecular weight:391.42Zoxamide
CAS:<p>Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [</p>Formula:C14H16Cl3NO2Color and Shape:SolidMolecular weight:336.64Inz-5
CAS:<p>Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.</p>Formula:C18H14F4N6Color and Shape:SolidMolecular weight:390.34Econazole
CAS:<p>Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.</p>Formula:C18H15Cl3N2OPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:381.68 g/molFengycin
CAS:<p>Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.</p>Formula:C72H110N12O20Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:1,463.71 g/mol2,4′-Dichloroacetanilide
CAS:<p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>Formula:C8H7Cl2NOPurity:99.36%Color and Shape:SolidMolecular weight:204.05Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formula:C22H21N4O6PPurity:98%Color and Shape:SolidMolecular weight:468.40Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formula:C24H26N4Se2Color and Shape:SolidMolecular weight:528.41CDA-IN-4
CAS:<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Formula:C10H9BrN4O2SColor and Shape:SolidMolecular weight:329.17
