Antivirals
Antivirals are compounds specifically designed to inhibit the replication and spread of viruses, playing a critical role in the treatment and prevention of viral infections. In this category, you will find a comprehensive selection of antiviral agents intended for laboratory research purposes only. These products are essential for studying viral mechanisms, developing new antiviral therapies, and understanding resistance patterns. Researchers can utilize these antivirals to investigate the efficacy and safety of potential treatments, contributing to the advancement of medical science and the development of innovative antiviral drugs. The availability of diverse antiviral agents supports cutting-edge research in virology and enhances our ability to combat viral diseases.
Found 762 products of "Antivirals"
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(S)-(5S,6S,8S)-5,8-Dibenzyl-12,12-dimethyl-3,10-dioxo-1-(thiazol-5-yl)-2,11-dioxa-4,9-diazatridecan-6-yl 2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate
CAS:Controlled Product<p>Applications (S)-(5S,6S,8S)-5,8-Dibenzyl-12,12-dimethyl-3,10-dioxo-1-(thiazol-5-yl)-2,11-dioxa-4,9-diazatridecan-6-yl 2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate is an protected prodrug of Ritonavir (R535000), which is a selective HIV protease inhibitor.<br></p>Formula:C42H56N6O7S2Color and Shape:NeatMolecular weight:821.06(R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic Acid Methyl Ester Trimethylamine
Controlled Product<p>Applications (R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic Acid Methyl Ester Trimethylamine is an intermediate in the synthesis of Tenofovir (T018500), is an acyclic phosphonate nucleotide analogue.<br>References Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C16H31N6O4PColor and Shape:NeatMolecular weight:402.431-Oxyl-2,2,5,5-tetramethyl-∆3-pyrrolinyl-4-pyridine Disulfide
Controlled Product<p>Applications A highly reactive thiol-specific spin-label. A specific conformational probe of thiol site structure by virtue of its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study.<br></p>Formula:C14H19N2OS2Color and Shape:NeatMolecular weight:295.443T-705RMP TEA Salt >80% (contain inorganics)
CAS:<p>Applications T-705RMP TEA Salt is a metabolite of T-705RMP (CAS# 356783-08-9), which is a reagent used for the preparation of pyrazine-ribofuranose derivatives as antiviral agents that are useful in the treatment of viral infections. T-705 (Favipiravir) [F103350] gets converted to T-705RMP by host cells, but T-705RMP has little inhibitory effect on the replication of the host cells based on biological studies.<br>References Zhong, B., et al.: Faming Zhuanli Shenqing, 2014:924257 (2014); Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005)<br></p>Formula:C10H13FN3O9P•xC6H15NColor and Shape:NeatMolecular weight:369.20 + x(101.19)Tenofovir diphosphate
CAS:<p>Tenofovir diphosphate is an antiviral compound, which is a key active metabolite derived from the prodrugs tenofovir disoproxil fumarate and tenofovir alafenamide, both originating from chemical synthesis. Its mode of action involves inhibiting the activity of HIV-1 reverse transcriptase by competing with the natural substrate, deoxyadenosine 5’-triphosphate, and causing chain termination after incorporation into viral DNA. This mechanism effectively prevents the replication of retroviral DNA, thus halting the progression of the infection.</p>Formula:C9H16N5O10P3Purity:Min. 95%Molecular weight:447.17 g/molFoscarnet sodium
CAS:<p>Foscarnet sodium is a pyrophosphate analog antiviral agent with action on viral DNA polymerase and is used for treating cytomegalovirus and herpes simplex virus infections.</p>Formula:CNa3O5PPurity:Min. 95%Color and Shape:White PowderMolecular weight:191.95 g/molAcetyl daclatasvir
CAS:<p>Acetyl daclatasvir is a direct-acting antiviral agent, which is chemically derived from a series of small-molecule inhibitors. The source of this compound lies in rational drug design, focusing on targeting specific viral proteins involved in the replication of hepatitis C virus (HCV). Its mode of action involves inhibiting the NS5A protein, a non-structural protein essential for HCV RNA replication and virion assembly. By binding to NS5A, acetyl daclatasvir disrupts the replication complex, effectively halting the virus's ability to multiply within the host cells.</p>Purity:Min. 95%Vidarabine monohydrate
CAS:<p>Vidarabine monohydrate is an antiviral agent with action on viral DNA polymerase to inhibit replication and is used for treating herpes simplex virus infections and varicella-zoster virus infections.</p>Formula:C10H13N5O4·H2OPurity:(¹H-Nmr) Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:285.26 g/molHCV-IN-30
CAS:<p>HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).</p>Formula:C36H44N6O4Purity:99.6%Color and Shape:SolidMolecular weight:624.77Stavudine-α,α,α,6-d4
CAS:Controlled Product<p>Applications Stavudine-alpha,alpha,alpha,6-d4 (CAS# 1219803-67-4) is a useful isotopically labeled research compound.<br></p>Formula:C10H8D4N2O4Color and Shape:NeatMolecular weight:228.242'-Fluoro-2'-deoxyuridine-5,6-d2
CAS:Controlled Product<p>Applications 2'-Fluoro-2'-deoxyuridine-5,6-d2 (CAS# 362049-50-1) is a useful isotopically labeled research compound.<br></p>Formula:C9H9D2FN2O5Color and Shape:NeatMolecular weight:248.215S-2-Amino-5-dibenzylamino-4-oxo-1,6-diphenylhex-2-ene
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Ritonavir.<br>References Sham, H., et al.: Bioorg. Med. Chem. Lett., 12, 3101 (2002),<br></p>Formula:C32H32N2OColor and Shape:NeatMolecular weight:460.61Tenofovir-O-((R)-9-(2-Hydroxypropyl)adenine)-phosphate ester
CAS:Controlled ProductFormula:C17H23N10O4PColor and Shape:Off-WhiteMolecular weight:462.43,4-Difluoroaniline-2,6-d2
CAS:Controlled Product<p>Applications 3,4-Difluoroaniline-2,6-d2 (CAS# 1061566-62-8) can be used in its derivative form as an antiviral agent for Hepatitis B.<br>References Qiu, Y.L., et.al., U.S. Pat. Appl. Publ., 187,(2019);<br></p>Formula:C6H3D2F2NColor and Shape:NeatMolecular weight:131.121-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine
CAS:Controlled Product<p>Impurity Atazanavir Impurity B<br>Applications An intermediate for the preparation of antiviral protease inhibitors. Atazanavir Impurity B<br>References Fassler, A., et al.: J. Med. Chem., 39, 3203 (1996), Bold, G., et al.: J. Med. Chem., 41, 3387 (1998).<br></p>Formula:C17H21N3O2Color and Shape:NeatMolecular weight:299.37Baloxavir-d4
CAS:Controlled ProductFormula:C25D4H16F2N2O4SColor and Shape:NeatMolecular weight:486.5244-(2-Pyridinyl)benzaldehyde
CAS:Controlled Product<p>Impurity Atazanavir Impurity (Pyridinyl Benzaldehyde)<br>Applications Reactive metabolite of atazanavir. Atazanavir Impurity; Pyridinyl Benzaldehyde impurity<br>References F. Li et al., Drug Metabolism and Disposition 39, 294 (2011)<br></p>Formula:C12H9NOColor and Shape:NeatMolecular weight:183.21(2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate
CAS:Controlled ProductFormula:C22H28O4SSiColor and Shape:NeatMolecular weight:416.615,6,7,8-Tetrahydro-1-naphthalenol
CAS:Controlled Product<p>Applications 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.<br>References Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);<br></p>Formula:C10H12OColor and Shape:NeatMolecular weight:148.2(S)-Methyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
CAS:Controlled ProductFormula:C17H21F2NO3Color and Shape:NeatMolecular weight:325.35
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