Backbone Sugars and Nucleobases
Found 1001 products of "Backbone Sugars and Nucleobases"
N2-Boc-guanine-9-acetic acid
CAS:N2-Boc-guanine-9-acetic acid is a versatile building block that is used as a reagent, speciality chemical and intermediate in the synthesis of complex compounds. It has shown high quality, high purity and usefulness as an intermediate in the synthesis of organic molecules. This compound can be used to generate large quantities of guanine derivatives which are important building blocks for many types of research chemicals. N2-Boc-guanine-9-acetic acid is also useful as a reaction component or scaffold in organic syntheses.Formula:C12H15N5O5Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:309.28 g/mol7-Cyano-7-deaza-2’-deoxyguanosine
CAS:7-Cyano-7-deaza-2’-deoxyguanosine is a pyrrole nucleoside analog that has been shown to inhibit the replication of herpes simplex virus type 1 and 2 in human cell lines. 7-Cyano-7-deaza-2’-deoxyguanosine is a synthetic nucleoside analog that is structurally similar to deoxyadenosine, but with a cyanide group instead of an oxygen atom. This compound has been shown to have the same biochemical properties as deoxyadenosine, including inhibiting the incorporation of uridine into RNA and DNA. In addition, 7-Cyano-7-deaza-2’-deoxyguanosine inhibits the synthesis of proteins from amino acids by competitive inhibition of ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides. The enzyme's functionFormula:C12H13N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:291.26 g/mol3-Benzyladenine
CAS:3-Benzyladenine is an alkylating agent that has been shown to inhibit the growth of certain bacteria. It has been used as a marker for epidemiological studies and in the production of monoclonal antibodies. 3-Benzyladenine binds to DNA by methylating the N7 position of guanine, which blocks DNA replication and transcription. 3-Benzyladenine also inhibits chloride transport in cells with a diet high in protein and prevents the growth of bacteria through hydrophobic interactions with cell membranes. The bactericidal activity of 3-benzyladenine can be increased by deuteration or base excision, which selectively destroys bacterial DNA.Formula:C12H11N5Purity:Min. 95%Color and Shape:PowderMolecular weight:225.25 g/mol3’-β-Amino-2’,3’-dideoxy-5-fluorouridine
CAS:Please enquire for more information about 3’-beta-Amino-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%Guanine
CAS:Guanine is a purine base that is found in the DNA and RNA of all living cells. It plays an important role as a component of the nucleic acid molecule, where it is paired with cytosine. Guanine is involved in many chemical reactions and biological processes, including protein synthesis and cell division. The lack of guanine can lead to deficiency symptoms such as hemolytic anemia or erythrocyte cytoplasmic inclusion bodies. Guanine has been shown to have chemiluminescent properties, which can be used to detect its presence in samples containing DNA or RNA. This reaction occurs when guanine reacts with hydrogen peroxide (H2O2) to form guanidine (HN=C(NH2)NH2). The reaction produces excited states that emit light at a wavelength of 395 nm when they return to their ground state. Guanidine also has electrochemical impedance spectroscopy properties, which can be used for analytical purposesFormula:C5H5N5OPurity:Min. 97.5 Area-%Color and Shape:PowderMolecular weight:151.13 g/molN6-(2-Isopentenyl)adenine
CAS:N6-(2-Isopentenyl)adenine is a component of some nucleic acid molecules and can be synthesized from adenosine. It is used in vitro as a matrix effect to enhance the production of enzymes that are involved in the synthesis of amino acids, peptides, and proteins. N6-(2-Isopentenyl)adenine has been shown to stimulate the activity of enzymes such as urease, glucose oxidase, and horseradish peroxidase. This compound has been found to inhibit the replication of infectious agents by binding to DNA or RNA. The enzyme activities that are stimulated by this substance are important for the synthesis of essential biochemical compounds such as proteins and amino acids. In addition, it has been shown that N6-(2-Isopentenyl)adenine can inhibit autoimmune diseases and cytokinin.Formula:C10H13N5Purity:Min. 95%Color and Shape:White PowderMolecular weight:203.24 g/mol3’-Azido-3’-deoxy-5-fluorouridine
CAS:Please enquire for more information about 3’-Azido-3’-deoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%5-Ethyluracil
CAS:5-Ethyluracil is a nucleobase that is structurally similar to thymine. It inhibits the replication of human mitochondrial DNA and herpes simplex virus type-1 (HSV-1) by binding with the viral nucleic acid. 5-Ethyluracil has been shown to be an effective antiviral agent in clinical trials, where it was found to inhibit the replication of HSV-1 in both HIV-positive and HIV-negative patients. 5-Ethyluracil has also been shown to have an inhibitory effect on mammalian cells and has been used for treatment of certain types of cancer. This drug's low energy makes it useful as a topical analgesic. The glycosidic bond makes this drug water soluble, which allows for its use as an antiseptic or disinfectant. 5-Ethyluracil is metabolized by hydrochloric acid, which produces urate, ammonia, and carbon dioxide. This drug can be
Formula:C6H8N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:140.14 g/mol2-Thioxanthine
CAS:2-Thioxanthine is a hydrated form of xanthine, which is a purine base that occurs in all living cells. This compound has been shown to be able to inhibit the growth of resistant mutants and the formation of atherosclerotic lesions in mice. 2-Thioxanthine also inhibits the transfer reactions that are required for bacterial DNA synthesis. The stability of 2-thioxanthine can be increased by forming stable complexes with hydrochloric acid and by reducing the pH to less than 7. 2-Thioxanthine has been shown to have genotoxic effects on mouse liver cells and human fibroblasts, as well as pharmacological properties against cardiovascular disease.Formula:C5H4N4OSPurity:Min. 95%Color and Shape:PowderMolecular weight:168.18 g/mol2,6-Diaminopurine hemisulfate
CAS:2,6-Diaminopurine hemisulfate salt is a fine chemical that can be used as a building block for research chemicals, reagents, and specialty chemicals. It has been shown to be useful in the synthesis of various types of complex compounds. 2,6-Diaminopurine hemisulfate salt is also versatile in the sense that it can be used as an intermediate in reactions or as a scaffold for chemical synthesis. This product has CAS number 69369-16-0.Formula:C5H6N6•(H2O4S)0Purity:Min. 95%Color and Shape:PowderMolecular weight:398.36 g/mol5,6-Diamino-1,3-dipropyluracil
CAS:5,6-Diamino-1,3-dipropyluracil (DAU) is a synthetic drug that acts as an adenosine receptor antagonist. DAU binds to the adenosine receptors in the brain and inhibits the binding of adenosine, which may result in an anti-congestive effect. DAU has been found to be a potent inhibitor of the A2A adenosine receptor at nanomolar concentrations. This inhibition may be due to its ability to form covalent bonds with the receptor or its affinity for or blocking of agonist binding sites on the receptor. It also has been shown to have affinity for dopamine receptors, although it is not yet known if this activity contributes to its anti-congestive effects.Formula:C10H18N4O2Purity:Area-% Min. 95 Area-%Color and Shape:PowderMolecular weight:226.28 g/mol3’-Deoxy-3’-fluoro-6-azauridine
CAS:Please enquire for more information about 3’-Deoxy-3’-fluoro-6-azauridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%5-Hydroxymethyluridine
CAS:5-Hydroxymethyluridine is a nucleoside that is synthesized from uridine. It has shown to be effective in the treatment of inflammatory diseases, such as rheumatoid arthritis, and also has antiviral activity against herpes simplex virus. 5-Hydroxymethyluridine has been shown to have a high affinity for hydrophilic interaction chromatography (HIC) and can be used to purify glycosylases. This compound can also inhibit the formation of cancer cells by inhibiting the transcriptional activity of RNA polymerase II. 5-Hydroxymethyluridine has been found to demethylate DNA while maintaining its ability to bind with DNA-dependent RNA polymerase II. This process is catalyzed by glycosylases and hydroxylases that are found in the body.
Formula:C10H14N2O7Purity:Min. 95%Color and Shape:PowderMolecular weight:274.23 g/mol6-Chlorouracil
CAS:Intermediate in the synthesis of alogliptinFormula:C4H3ClN2O2Color and Shape:White Slightly Yellow PowderMolecular weight:146.53 g/mol8-Aminopurine
CAS:8-Aminopurine is an aminopurine that is used as a research tool in magnetic resonance spectroscopy. The proton magnetic resonance spectrum of 8-aminopurine shows two characteristic peaks at 3.0 and 4.2 ppm, which are assigned to the aminopurine tautomers (3-HPA, 4-HPA). The kinetic stability of 8-aminopurine in water is pH dependent and has been shown to be strongly dependent on the presence of aldehyde oxidase (AO) activity. AO activity can be inhibited by the addition of dimethylformamide or other non-specific inhibitors such as 2,6-dichloroisonicotinic acid.
Formula:C5H5N5Purity:Min. 95%Color and Shape:White PowderMolecular weight:135.13 g/molN9-Benzyladenine
CAS:N9-Benzyladenine is a drug that regulates the activity of adenosine receptors. It is an endogenous substance found in plants and animals, but can also be synthesized chemically. N9-Benzyladenine has been shown to inhibit protein synthesis by binding to cyclic nucleotide phosphodiesterases, resulting in the accumulation of cyclic AMP and activation of adenylate cyclase. This leads to an increase in intracellular cAMP levels that is mediated by Gs protein coupled receptors. N9-Benzyladenine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the release of tumor necrosis factor-α (TNF-α).
Formula:C12H11N5Purity:Min. 95%Color and Shape:PowderMolecular weight:225.25 g/mol6-Methyluracil
CAS:6-Methyluracil is an antimetabolite that inhibits protein synthesis and is therefore used in the treatment of infectious diseases. 6-Methyluracil has two hydroxyl groups, which are located in adjacent positions on the ring. The optimum concentration for this drug is 3-10 μM, which can be achieved with a malonic acid buffer solution at pH 7.4. 6-Methyluracil reacts with sodium succinate to form an acid complex, which may have antiinflammatory activity. 6-Methyluracil has been shown to inhibit prostaglandin synthesis and exhibits a reaction with radiation to produce photoproducts that can be detected by analytical chemistry.Formula:C5H6N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:126.12 g/mol5-Aminouracil
CAS:5-Aminouracil is a pyrimidine nucleoside that is used in the treatment of cancer, psoriasis and other autoimmune disorders. 5-Aminouracil is a prodrug that undergoes intracellular transformation to become an inhibitor of DNA synthesis. It promotes apoptosis by inhibiting the production of RNA and protein synthesis, leading to cell death. 5-Aminouracil has been shown to be effective against malignant cells in tissue culture as well as various types of cancer cells. A study using hydrogen bonding interactions showed that 5-aminouracil binds to the ribosomal protein L10 and inhibits its function in the polymerase chain reaction (PCR). Molecular docking studies have also shown that this drug can bind with redox potentials in both the active site and ligand binding site of human topoisomerase II alpha, which may lead to inhibition of enzyme activity or cell death.Formula:C4H5N3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:127.1 g/molN2,9-Diacetylguanine
CAS:N2,9-Diacetylguanine is a synthetic molecule that can be used to inhibit the replication of herpes simplex virus. It has been found to inhibit the growth of viruses in vitro by binding to the viral DNA and inhibiting viral RNA synthesis. N2,9-Diacetylguanine is also a substrate for acetylation and may undergo this reaction with acetyl coenzyme A to form N4,9-diacetylguanine. The acetylated form of guanine inhibits the virus by blocking its ability to replicate DNA. The potential mechanism for this drug's anti-viral activity includes inhibition of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides.Formula:C9H9N5O3Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:235.2 g/mol3’-Azido-3’-deoxyguanosine
CAS:Please enquire for more information about 3’-Azido-3’-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C10H12N8O4Purity:Min. 95%Molecular weight:308.09815
