Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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N6-Dibenzoyl-3-deaza-2'-deoxy-5'-O-DMT-3-methyladenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-3-deaza-2'-deoxy-5'-O-DMT-3-methyladenosine 3' is a nucleoside that has been modified to be resistant to the enzymatic degradation by ribonucleases. The phosphoramidite is used in the synthesis of DNA and can be used as an antiviral or anticancer drug. It also acts as a competitive inhibitor of adenosine deaminase, which is an enzyme involved in the metabolism of purines. N6-Benzoyl-3-deaza-2'-deoxy-5'-O-DMT-3 methyladenosine 3' can inhibit viral replication by inhibiting RNA polymerase activity, and it has been shown to have antifungal properties.Formula:C56H59N6O8PPurity:Min. 95%Molecular weight:870.99 g/mol4'-α-C-Methylcytidine
CAS:4'-a-C-Methylcytidine is a nucleoside that is synthesized from 4'-a-C-methyluridine. It has antiviral and anticancer properties, and has been shown to be a potent activator of the immune system. The modified nucleosides in this compound are thought to be less toxic than other cytotoxic agents. 4'-a-C-Methylcytidine is also used as a building block for the synthesis of DNA, RNA and phosphoramidites.Purity:Min. 95%Color and Shape:PowderMolecular weight:257.24 g/mol6-Methyluridine
CAS:Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.Formula:C10H14N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:258.23 g/mol2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine
CAS:2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.Formula:C9H10FN3O3Purity:Min. 95%Molecular weight:227.19 g/mol2'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.
Formula:C11H15N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:281.27 g/mol5-Bromo-2'-deoxycytidine
CAS:5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.Formula:C9H12BrN3O4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:306.11 g/mol2-O-Ethylthymidine
CAS:2-O-Ethylthymidine is a nucleoside that is used to study the structure and dynamics of DNA. It can be synthesized by reacting 1-β-D-arabinofuranosylbenzene with ethylmercury acetate. 2-O-Ethylthymidine can be used in kinetic studies as it is specific for dna. It has been shown to have a conformational change, which is stabilized by the presence of an aromatic ring such as phenanthrene. This compound was also found to inhibit neuroblastoma cell growth in vitro.
Formula:C12H18N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:270.28 g/molCaffeoyl-coenzym A
CAS:Please enquire for more information about Caffeoyl-coenzym A including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C30H42N7O19P3SPurity:Min. 95%Molecular weight:929.68 g/mol5-Iodocytidine 5'-triphosphate sodium salt - 100mM solution
CAS:5-Iodocytidine 5'-triphosphate sodium salt is a novel antiviral agent. It is the sodium salt of 5-iodocytidine 5'-triphosphate and is used to inhibit viral replication. It inhibits RNA synthesis by interfering with the incorporation of deoxyribonucleosides into the growing DNA chain, which blocks DNA synthesis. This inhibition prevents virus production and may be useful in treating cancer.Formula:C9H15IN3O14P3Purity:Min. 95%Molecular weight:609.05 g/molOleoyl coenzyme A lithium salt
CAS:Oleoyl coenzyme A lithium salt is a fatty acid that belongs to the class of organic compounds known as aliphatic acyl-coenzyme A. It is synthesized by the enzyme synthetase and can be used to diagnose cascading, linear response, and aldehyde synthesis in carbon nanotubes. Oleoyl coenzyme A lithium salt has been shown to bind to sephadex G-100 and immobilize it on a surface. This immobilization process aids in the diagnosis of various diseases such as diabetes mellitus, cancer, and cardiovascular problems. The chloride anion present in oleoyl coenzyme A lithium salt buffers and stabilizes the pH levels during this process. Oleoyl coenzyme A lithium salt also binds to multi-walled carbon nanotubes (MWNTs) due to its hydrophobic nature, which aids in the detection of markers such as lipids or proteins using immunological techniques.Formula:C39H68N7O17P3S·xLiPurity:Min. 95%Molecular weight:1,031.98 g/molMalonyl coenzyme A lithium salt - 90%
CAS:Malonyl coenzyme A lithium salt - 90% is a fatty acid that is involved in the biosynthesis of fats. It is also involved in the synthesis of prostaglandins, which are hormone-like substances that have a wide variety of effects on many different tissues. Malonyl coenzyme A lithium salt - 90% may be useful for the treatment of insulin resistance and obesity due to its ability to stimulate glucose uptake by fat cells and increase insulin sensitivity. The following product details are for a supplement:Formula:C24H38N7O19P3S·xLiPurity:Min. 95%Molecular weight:853.58 g/mol5'-o-DMT-N4-benzoyl-5-methyl-2'-o-methylcytidine 3'-ce phosphoramidite
CAS:5'-O-DMT-N4-benzoyl-5-methyl-2'-O-methylcytidine 3'-ce phosphoramidite is a high purity, diphosphate, CAS No. 166593-57-3, Modified, Anticancer, DNA. It is a novel activator monophosphate that can be used for the synthesis of phosphoramidites for oligonucleotide synthesis and as a novel building block for nucleosides and deoxyribonucleosides. 5'-O-DMT-N4-benzoyl-5-methyl-2'-O-methylcytidine 3'-ce phosphoramidite has been shown to have anticancer activity in vitro. The cytotoxic effect of this compound is mediated by its ability to inhibit DNA replication and induce apoptosis in human leukemia cells.Formula:C48H56N5O9PPurity:Min. 95%Molecular weight:878.00 g/molN2-Acetyl-5'-O-DMT-guanosine
CAS:N2-Acetyl-5'-O-DMT-guanosine is a novel anticancer nucleoside that has been synthesized to mimic the natural nucleotides found in DNA. It is phosphorylated to N2-acetyl-5'-O-DMT-guanosine monophosphate, which can be converted back to the active form of N2-acetyl-5'-O-DMT guanosine by phosphatases. This agent activates DNA synthesis and inhibits viral replication, including HIV and herpes simplex virus. The antiviral activity is due to its inhibition of viral DNA polymerase and diphosphate kinase.
Purity:Min. 95%Uridine-3',5'-cyclic monophosphate sodium salt
CAS:Uridine-3',5'-cyclic monophosphate sodium salt is a phosphotriester that is an intermediate in the biosynthesis of nucleosides. It is also a phosphodiesterase inhibitor, which means it inhibits the breakdown of cyclic nucleotides and allows them to accumulate. This drug has been shown to increase platelet production and has anti-inflammatory effects. Uridine-3',5'-cyclic monophosphate sodium salt is a human metabolite that can be synthesized from uridine, which is present in DNA, RNA, and food sources such as meat, eggs, and milk. The synthesis of uridine-3',5'-cyclic monophosphate sodium salt requires phosphoramidite as a precursor.
Formula:C9H10N2O8P·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:328.2 g/mol2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite
CAS:2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite is a novel nucleoside analog that inhibits viral DNA replication and has antiviral properties. It is an effective inhibitor of HIV, HSV, and HCV. The drug works by binding to the viral DNA polymerase enzyme, thereby blocking the RNA-dependent DNA polymerase activity and inhibiting viral DNA synthesis. 2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite is a modified nucleoside with a fluorine atom at the 5' position of the sugar moiety, which prevents phosphodiester cleavage by phosphodiesterases in the cell's cytoplasm. This drug also has anticancer effects on human cancer cells by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase.Formula:C40H46FN6O7PPurity:Min. 95%Molecular weight:772.8 g/molZeatin riboside
CAS:Zeatin riboside is a naturally occurring compound that belongs to the group of nucleotides. It is synthesized in plants and bacteria, and has been shown to have physiological activities in both these organisms. Rootstocks are typically used as the optimum concentration for zeatin riboside. Zeatin riboside has been shown to be effective against bacterial strains that cause plant diseases, such as bacterial strain Xanthomonas campestris pv. corylina. Zeatin riboside also inhibits the growth of plant pathogens by increasing adenine nucleotide levels in root cells, which leads to an increase in photosynthetic activity and a decrease in the production of chemical pesticides. The optimum pH for zeatin riboside is 8-9.Formula:C15H21N5O5Purity:Min. 90%Color and Shape:PowderMolecular weight:351.36 g/molAdenosine 5′-O-(1-thiotriphosphate) sodium, mixture of R and S isomers
Please enquire for more information about Adenosine 5′-O-(1-thiotriphosphate) sodium, mixture of R and S isomers including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H16N5O12P3S•Na3Purity:Min. 95%Molecular weight:592.25 g/molStearoyl coenzyme A free acid hydrate
CAS:Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).Formula:C39H70N7O17P3S•H2OPurity:Min. 92 Area-%Color and Shape:White PowderMolecular weight:1,052.01 g/mol7-Deaza-2'-C-ethynyladenosine
CAS:7-Deaza-2'-C-ethynyladenosine (7DAA) is a research inhibitor that is classified as a polymerase inhibitor. It binds to the active site of the viral NS5B polymerase and inhibits RNA synthesis, which leads to virus replication. 7DAA has shown activity against hepatitis B virus (HBV) and hepatitis C virus (HCV). It also shows multifunctional properties in its inhibition of HBV genotypes A1, A3, and D1. In addition, 7DAA interacts with the RNA binding site on HCV polymerase protein and prevents binding of the viral RNA genome to this site. 7DAA also inhibits HIV replication by preventing assembly of the reverse transcriptase enzyme complex at an early stage.Formula:C13H14N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:290.27 g/mol2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite
2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite is a 5'-3’ “reverse” (or “inverse”) amidite.Formula:C44H54N7O8PPurity:Min. 95%Molecular weight:839.94 g/mol2-Methylamino-N6-methyladenosine
CAS:2-Methylamino-N6-methyladenosine is an activator that can inhibit the replication of DNA, RNA, and protein synthesis. It is a novel monophosphate nucleoside with antiviral and anticancer properties. 2-Methylamino-N6-methyladenosine has been shown to be effective against human cytomegalovirus and murine leukemia virus (MLV) in cell culture. Furthermore, it has been shown to be active against the herpes simplex virus type 1 (HSV1) in mice after oral administration. 2-Methylamino-N6-methyladenosine is a modified deoxyribonucleoside that contains an amino group at the 2' position of the ribose sugar moiety. It also contains an alkyl group at the 6 position of adenine. This modification confers increased stability to the molecule, which prevents degradation by intracellular nucleases.Purity:Min. 95%8-Nitroguanosine
CAS:8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.Formula:C10H12N6O7Purity:Min. 95%Molecular weight:328.24 g/molDMT-2′O-TC-rC(ac) Phosphoramidite
CAS:DMT-2²O-TC-rC(ac) Phosphoramidite is a novel nucleoside that has been modified with a 2,2'-O, TC-rC(ac) group. This compound is an analogue of the natural nucleoside cytidine and can be used in both DNA and RNA synthesis. DMT-2²O-TC-rC(ac) Phosphoramidite is phosphorylated by ATP to form diphosphate, which is then incorporated into DNA or RNA. The CAS number for this compound is 1219089-87-8.Formula:C46H57N6O11PS2Purity:Min. 95%Color and Shape:PowderMolecular weight:965.08 g/mol3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin
CAS:3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a nucleoside analog that is used as an activator of phosphoramidite. It can be used as a building block in the synthesis of modified phosphoramidites and it has antiviral, anticancer, and antiinflammatory properties. 3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a novel nucleoside analog that can be used to synthesize DNA or RNA. It is also an inhibitor of deoxyribonucleoside kinase, preventing the conversion of deoxyribonucleosides into diphosphate monophosphates.
Formula:C12H15N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:309.28 g/mol2',3',5'-Tri-O-acetyl-8-bromoguanosine
CAS:2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.
Formula:C16H18BrN5O8Purity:Min. 95%Color and Shape:Off-White To Light (Or Pale) Yellow SolidMolecular weight:488.25 g/mol3'-O-Methylinosine
CAS:3'-O-Methylinosine is a synthetic nucleoside that inhibits the synthesis of viral DNA and RNA by interacting with the enzyme ribonucleotide reductase. This antiviral agent has been shown to be effective against a wide range of viruses, including human cytomegalovirus, herpes simplex virus type 1, varicella-zoster virus, and influenza A virus. 3'-O-Methylinosine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.
Formula:C11H14N4O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:282.25 g/molCiticoline sodium
CAS:Citicoline is a complex organic molecule, a form of B-vitamin choline that acts as an intermediate in many biosynthetic pathways, for example, in the biosynthesis of cell membrane phospholipids. As a dietary supplement, citicoline is a source of choline and cytidine, two components that are quickly absorbed in the intestine and across the blood-brain barrier. The neuroprotective properties of citicoline improves mental performance increasing the levels of other brain-related chemicals like dopamine and norepinephrine, helping with recovery in stroke patients, reducing memory loss due to aging and improving vision in patients with glaucoma.Formula:C14H26N4O11P2•NaPurity:Min. 98.0 Area-%Color and Shape:White To Off-White SolidMolecular weight:511.31 g/mol9-(beta-D-Xylofuranosyl)guanine
CAS:9-(β-D-xylofuranosyl)guanine (9XG) is a trifluoride. It is an antiviral agent that inhibits the growth of herpes virus, in particular by methylating guanosine to 9-methylguanosine in the viral DNA. 9XG binds to the viral DNA and prevents its replication through the inhibition of RNA synthesis. The drug is active against many different types of viruses and has been shown to be effective against tissue cultures infected with herpes virus. 9XG is synthesized from guanosine and boron trifluoride etherate, which are reacted at -78 degrees Celsius for three days. This yields a mixture of compounds with various peracylation groups, which are then separated by chromatography.
Purity:Min. 95%Guanosine5'-diphosphate
CAS:Pyruvate kinase substrateFormula:C10H15N5O11P2Purity:Min. 95%Color and Shape:PowderMolecular weight:443.2 g/molN6-Aminoadenosine
CAS:N6-Aminoadenosine is a purine nucleoside that is involved in the synthesis of adenosine. It can be found in a number of tissues and has been shown to have an agonist potency similar to 2-phenylaminoadenosine, but with a longer duration of action. N6-Aminoadenosine is also present as one of two stereoisomers, the other being N2-aminoadenosine. These two aminosides are hydrolyzed by triazol and sinoatrial enzymes. The affinity of N6-aminoadenosine for cellular receptors has been shown using high affinity assays on rat heart cells.Purity:Min. 95%3'-O-Propargyladenosine
CAS:3'-O-Propargyladenosine is a modified nucleoside that has antiviral and anti-inflammatory properties. It is a synthetic compound that is chemically related to adenosine. 3'-O-Propargyladenosine is an activator of the immune system and it inhibits viral DNA synthesis. The compound also has been shown to reduce inflammation in mice by inhibiting the production of prostaglandin E2 (PGE2). 3'-O-Propargyladenosine has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and cytomegalovirus (CMV).Formula:C13H15N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:305.29 g/mol5′-O-DMT-LNA N-Bz 5-Me cytidine
CAS:5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.Formula:C39H37N3O8Purity:Min. 95%Molecular weight:675.73 g/mol4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester
CAS:Focuses is a chemical compound that does not have any known commercial or industrial uses.Purity:Min. 95%2'-Deoxyuridine-5'-monophosphate disodium salt
CAS:2'-Deoxyuridine-5'-monophosphate disodium salt (2DUMP) is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase. 2DUMP is a covalent inhibitor of thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. This compound has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2DUMP is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus. It has been shown to bind to benzalkonium chloride (BAK) in biological samples such as serum or plasma. 2DUMP binds to BAK through a covalent linkage between the 3' hydroxyl group on BAK and the phosphate group on 2DUMPFormula:C9H11N2O8PNa2Purity:Min. 95%Color and Shape:PowderMolecular weight:352.15 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:Inhibitor of adenylyl and guanylyl cyclaseFormula:C10H15N4O15P3·xC6H15NPurity:Min. 95%Color and Shape:Colorless PowderMolecular weight:524.17 g/mol2'-Deoxyguanosine-[15N5] monohydrate
CAS:2'-Deoxyguanosine-[15N5] monohydrate is a chemical compound that has been shown to have anticancer activity in colorectal adenocarcinoma cells. The high-activity form of this compound is produced by the addition of a 15N isotope, which can be detected using an electrochemical detector. This compound inhibits the enzyme DNA methyltransferase, preventing the addition of methyl groups to DNA and thereby inhibiting cell growth. 2'-Deoxyguanosine-[15N5] monohydrate also has anti-inflammatory properties due to its ability to inhibit IL-2 receptor signaling.Formula:C10H13N5O4·H2OPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:285.26 g/mol3'-Deoxycytidine-5'-triphosphate
CAS:3'-Deoxycytidine-5'-triphosphate is a modified nucleoside that is the precursor for DNA synthesis. It is an activator of deoxyribonucleoside triphosphates, which are needed in the production of DNA. 3'-Deoxycytidine-5'-triphosphate has been shown to be active against cancer cells and antiviral agents. This chemical also inhibits viral RNA synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. 3'-Deoxycytidine-5'-triphosphate is novel and high purity, with a CAS number 69383-05-7.
Purity:Min. 95%Molecular weight:467.1 g/molWyosine
CAS:Wyosine is a glycosylated protein that is found in the mitochondria of eukaryotic cells. It has been shown to have an acidic pH and to be non-covalently bound to a molecule with a molecular weight of approximately 2,000 Da. Wyosine binds to the wild-type strain of the bacterium Mycobacterium tuberculosis, which may play a role in its biological properties. This molecule also reacts with antibodies and can be used as an antigen for antibody production. Wyosine is structurally similar to x-ray crystal structures and has been observed by X-ray crystallography at atomic resolution.Formula:C14H17N5O5Purity:Min. 95%Molecular weight:335.32 g/mol5-Bromo-2'-deoxy-4-thiouridine
CAS:5-Bromo-2'-deoxy-4-thiouridine is a high purity, diphosphate nucleoside with novel anticancer activity. It is a potent activator of the transcription factor NF-kappaB and inhibits the proliferation of cancer cells. 5-Bromo-2'-deoxy-4-thiouridine has been shown to be an effective antiviral agent against HIV and hepatitis B virus in vitro. This compound also inhibits the synthesis of DNA and RNA in human cells, which may be due to its ability to inhibit thymidylate synthase. 5-Bromo-2'-deoxy-4-thiouridine is not active against bacterial cells because they lack thymidylate synthase.Purity:Min. 95%N6-Acetyl-2'-deoxyadenosine
CAS:N6-Acetyl-2'-deoxyadenosine is an antiviral and anticancer nucleoside. It is a novel modified nucleoside that has been synthesized with a high degree of purity. N6-Acetyl-2'-deoxyadenosine is active against HIV, Hepatitis C, and other viruses, as well as cancer cells. It also inhibits the activity of bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. N6-Acetyl-2'-deoxyadenosine has a phosphoramidite structure and is synthesized from 2'-deoxyribonucleosides.Formula:C12H15N5O4Purity:Min. 95%Molecular weight:293.28 g/molN-Acetyl-2'-deoxy-2',2'-difluorocytidine
CAS:N-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside analog. It is phosphorylated at the 5' position and converted to a monophosphate by adenylyl cyclase, which is an enzyme that catalyzes the conversion of ATP to cyclic AMP. This nucleoside analog has antiviral activity in vitro and in vivo against HIV-1. It also has been shown to inhibit DNA replication of human cells infected with herpes simplex virus type 1 (HSV-1).Formula:C11H13F2N3O5Purity:Min. 95%Molecular weight:305.23 g/molAbacavir 5'-phosphate
CAS:Abacavir 5'-phosphate is a nucleoside analog that inhibits the replication of the herpes virus by covalently binding to the viral DNA polymerase and blocking its ability to polymerize dNTPs. Abacavir 5'-phosphate's anti-viral potency has been shown in vivo using a model with herpes simplex virus, and it has been shown to inhibit viral replication in cell culture. The drug also reacts with cellular components such as proteins, lipids, and nucleic acids, which may lead to drug reactions. Abacavir 5'-phosphate is chemically stable, so it can be subjected to analytical methods without degradation. It is an analog of zidovudine (AZT).
Formula:C14H19N6O4PPurity:Min. 95%Molecular weight:366.31 g/mol2'-O-Methyladenosine 5'-monophosphate triethylammonium salt
CAS:2'-O-Methyladenosine 5'-monophosphate triethylammonium salt is an antiviral nucleoside that is used in the treatment of hepatitis B and C. It is a modified nucleoside that inhibits the replication of RNA by binding to the enzyme ribonuclease, which plays a vital role in the synthesis of DNA. 2'-O-Methyladenosine 5'-monophosphate triethylammonium salt also has anticancer properties and can inhibit DNA synthesis. This compound is a novel phosphoramidite building block for oligonucleotide synthesis and has been shown to be an activator for deoxyribonucleosides.Formula:C11H16N5O7PPurity:Min. 95%Molecular weight:361.25 g/mol2'-Deoxyinosine-5'-triphosphate sodium
CAS:2'-Deoxyinosine-5'-triphosphate sodium is a nucleoside that is used as an antiviral, anticancer and novel drug. It inhibits viral replication by inhibiting DNA synthesis in the cell. 2'-Deoxyinosine-5'-triphosphate sodium binds to viral RNA polymerase, preventing the enzyme from creating new DNA strands. This prevents the virus from replicating and spreading to other cells in the body. 2'-Deoxyinosine-5'-triphosphate sodium has been shown to inhibit cancer growth by binding to DNA, which prevents it from dividing and creating new cells. This drug also has antiviral activity against HIV and Herpes Simplex Virus Type 1 (HSV1). 2'-Deoxyinosine-5'-triphosphate sodium is typically used as a buffer solution for peptide synthesis or as a chemical intermediate for various organic syntheses.Formula:C10H15N4O13P3·xNaPurity:Min. 95%Color and Shape:White PowderMolecular weight:492.17 g/molValopicitabine
CAS:Valopicitabine is a prodrug that is converted to its active form, 3'-deoxy-3'-methylvalopicitabine, in the body. Valopicitabine inhibits viral replication by a mechanism that is not yet fully understood. It has been shown to inhibit NS3 protease and induce an interferon response. Valopicitabine has also been shown to inhibit Toll-like receptor 4 (TLR4) activity and elicit an antiviral response. Valopicitabine has low bioavailability, which may be due to its high lipophilicity.Formula:C15H24N4O6Purity:Min. 95%Molecular weight:356.37 g/mol[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is an antiviral and anticancer nucleoside phosphoramidite. It is synthesized by reacting the purified 6-(N4-benzoylcydin-1-yl) morpholine with dimethyl phosphorochloridate in pyridine at room temperature. This novel monophosphate nucleoside has been shown to be efficacious against human immunodeficiency virus (HIV) and murine leukemia virus (MLV). The antiviral activity of [(2S,6R)-6-(N4-benzoylcydin-1-yl)-4-(tritylmorpholin]-2(1H)-yl]methyl dimethylphosphoramidochloridate is due to its ability
Formula:C37H37ClN5O5PPurity:Min. 95%Color and Shape:PowderMolecular weight:698.15 g/mol1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indole
CAS:Please enquire for more information about 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C13H14N2O5Purity:Min. 95%Molecular weight:278.26 g/mol5'-o-(4,4'-Dimethoxytrityl)-2'-deoxythymidine-3'-(methyl-N,N-diisopropyl)phosphoramidite
CAS:Please enquire for more information about 5'-o-(4,4'-Dimethoxytrityl)-2'-deoxythymidine-3'-(methyl-N,N-diisopropyl)phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C38H48N3O9PPurity:Min. 95%Molecular weight:721.8 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-monophosphate
CAS:10umol is approximately 5mg.2'-O-(2-Methoxyethyl)adenosine 5'-monophosphate is a nucleoside compound that has been phosphorylated in the 5'-position.Purity:Min. 95%2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine
CAS:2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine (DBBA) is a modified nucleoside with anticancer, antiviral, and synthetic properties. It can be used as a building block for the synthesis of DNA, RNA, or other nucleotide analogues. DBBA has shown activity against certain cancer cells and has been found to inhibit the replication of HIV and herpes simplex virus type 1 in cell culture. DBBA is also known as 2',3'-Dibenzoyl-N6-benzoyladenosine.Formula:C31H25N5O7Purity:Min. 95%Molecular weight:579.56 g/mol2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine
CAS:Please enquire for more information about 2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C14H19N5O4Purity:Min. 95%Molecular weight:321.33 g/mol4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution is thio-base modified thymidine nucleotideFormula:C10H17N2O13P3S·xLiPurity:Min. 95%Molecular weight:498.23 g/mol2',3'-Dehydro-5'-O-tritylthymidine
CAS:2',3'-Dehydro-5'-O-tritylthymidine is an anticancer compound, which is a novel nucleoside phosphoramidite. It is synthesized from thymidine in two steps: first, the 2',3'-dideoxyribose phosphate moiety is prepared by reacting 2',3'-dideoxyribose with chloroacetic acid in the presence of triethylamine, followed by reaction with trityl chloride to form the 5' position of the thymidine. 2',3'-Dehydro-5'-O-tritylthymidine has been shown to inhibit DNA synthesis and antiviral activity.Formula:C29H26N2O4Purity:Min. 95%Molecular weight:466.54 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease and
Formula:C11H17N4O13P3·xNaPurity:Min. 95%Molecular weight:506.19 g/mol5-Fluorouridine-5'-diphosphate sodium
CAS:5-Fluorouridine-5'-diphosphate sodium salt is a nucleoside analog that inhibits the synthesis of RNA and DNA. It is used to treat cancer, as well as opportunistic infections, such as cryptococcal disease. 5-Fluorouridine-5'-diphosphate sodium salt binds to the enzyme thymidylate synthase and prevents it from synthesizing dTMP, which is needed for DNA synthesis. This drug also has been shown to be effective against monoclonal antibodies in mice with cancer. 5-Fluorouridine-5'-diphosphate sodium salt may also be useful in gene therapy for cancer treatment. This drug can be taken up by cells where it is converted into uracil, which inhibits protein synthesis by competing with the natural substrate tRNA for binding sites on ribosomes.Formula:C9H13FN2O12P2•NaxPurity:Min. 95%Color and Shape:PowderMolecular weight:423.16 g/mol2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water
CAS:2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water is a nucleotide analog that inhibits the synthesis of RNA. It is used for the treatment of cancer. This agent binds to DNA and prevents the formation of RNA by inhibiting the enzyme ribonucleotide reductase. 2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water also has a perchloric acid component, which may be responsible for its haematopoietic effects.
Formula:C9H14FN2O14P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:486.13 g/molLauroyl coenzyme A potassium salt
CAS:Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymerFormula:C33H55N7O17P3SK3Purity:Min. 95%Color and Shape:PowderMolecular weight:1,064.11 g/molDoubler phosphoramidite
CAS:Please enquire for more information about Doubler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C64H79N4O10PMolecular weight:1,095.31 g/mol2,2'-Anhydro-L-thymidine
CAS:2,2'-Anhydro-L-thymidine is an antiviral, anticancer agent and a synthetic nucleoside. It is a monophosphate that was first synthesized in 1967 and has been used as a potential antiviral agent. 2,2'-Anhydro-L-thymidine has been shown to be effective against the herpes simplex virus type 1 (HSV1). However, it does not inhibit viral nucleic acid synthesis or viral protein synthesis. It also does not inhibit the growth of tumor cells in culture.Formula:C10H12N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:240.21 g/molThymidine 3'-monophosphate sodium salt
CAS:Thymidine 3'-monophosphate sodium salt (TMP) is a nucleoside that is involved in the synthesis of DNA. TMP has been shown to have minimal carcinogenic effects on the liver, with no effect on the rate of DNA synthesis or cell proliferation in vivo. It has been shown to be hepatotoxic and genotoxic in animal studies and can cause DNA strand breaks and chromosomal aberrations in liver cells. TMP also causes a specific adduct, crotonaldehyde, which is considered to be an indicator of hepatic injury. The detection method for this adduct uses gas chromatography-mass spectrometry, which identifies the presence of TMP by detecting its unique mass spectrum.Formula:C10H15N2O8P•xNaPurity:Min. 95%Color and Shape:Powder2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite is a DNA synthesis reagent that is used in the preparation of oligonucleotides, in particular for the synthesis of 2'-deoxyribonucleosides. It has been shown to be an activator and to have anticancer, antiviral, and antimalarial properties. This compound is synthesized by reacting 5'-O-DMT cytidine with 2',3' epoxypropyltrichlorophosphite. The product is purified by silica gel column chromatography and recrystallization from ethanol followed by vacuum drying. CAS No. 149989-66-2Formula:C57H76N5O10PSiPurity:Min. 95%Molecular weight:1,050.3 g/molCytidine 5'-diphosphoglycerol disodium salt
CAS:Cytidine 5'-diphosphoglycerol disodium salt is a modified nucleotide that belongs to the group of phosphoramidites. It is a cytidine derivative with a 2-hydroxymethylene bridge, which makes it resistant to degradation by cytidine deaminase and therefore enhances its anticancer activity. Cytidine 5'-diphosphoglycerol disodium salt has been shown to inhibit the growth of cancer cells in vitro and in vivo models, as well as inhibit viral replication. Cytidine 5'-diphosphoglycerol disodium salt is stable at high temperatures and can be used for activation of DNA synthesis in vitro. This product has not been tested on animals or humans and should not be taken internally.Formula:C12H19N3Na2O13P2Purity:Min. 95%Molecular weight:521.22 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite is a modified phosphoramidite that can be used to synthesize DNA oligomers. The nucleoside is an antiviral and antitumor agent. It is also used to inhibit the replication of RNA by inhibiting the activity of DNA polymerase. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite has novel properties that have not been seen in any other nucleosides. This product is for research use only, not for diagnostics or therapeutic purposes.
Formula:C51H51N6O7PS2Purity:Min. 95%Molecular weight:955.09 g/mol2-Amino-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-N2-(isobutyryl)-2'-O-methyladenosine
CAS:DMF functionalised 2'-O-methyladenosine
Formula:C39H45N7O7Molecular weight:723.82 g/mol7-Deaza-2'-deoxy-7-ethynyladenosine
CAS:7-Deaza-2'-deoxy-7-ethynyladenosine is a fluorescent analog of adenosine that has been synthesized to be used as an antimicrobial agent. This compound has shown to be effective against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus and Escherichia coli. 7DDAE is also able to inhibit the growth of fungus and yeast, such as Candida albicans. This drug has been shown to have no cytotoxic effects on mammalian cells at concentrations up to 50 μM. 7DDAE has been found to be very photostable in solution, which means it does not degrade when exposed to light.
Formula:C13H14N4O3Purity:Min. 95%Color and Shape:PowderMolecular weight:274.28 g/moldG-MGO
CAS:Methylglyoxal (MGO) is a reactive byproduct formed by several metabolic precursors notably glycolysis. dG-MGO is therefore a useful marker to in monitoring various glycation pathwaysFormula:C13H17N5O7Molecular weight:355.3 g/molGuanosine-2'(&3')-monophosphate disodium (mixed isomers)
CAS:Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is a synthetic nucleoside with antiviral and anticancer properties. It has been shown to activate the transcription of DNA in vitro by binding to the promoter region, resulting in higher levels of RNA synthesis. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) has been shown to inhibit the replication of viruses, such as herpes simplex virus type 1 (HSV-1), and it may have potential use in cancer therapy. The drug is also used as a precursor for other antiviral drugs and antibiotics. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is available in high purity, high quality, and at low cost.Formula:C10H14N5O8P•2NaPurity:Min. 95%Color and Shape:White PowderMolecular weight:407.18 g/molOctanoyl coenzyme A lithium salt hydrate
CAS:Octanoyl coenzyme A lithium salt hydrate (OCCA) is a metabolite of octanoic acid, which is formed by the oxidation of fatty acids. OCCA has been shown to have relevance in the metabolism of fatty acids, as it can be conjugated with other molecules and transported into cells. This compound has been detected in human liver tissues and was found to be metabolized by primary rat hepatocytes in vitro. The metabolic pathway of OCCA is not yet fully understood, but it has been investigated in vivo studies.Formula:C29H50N7O17P3S·xLi·yH2OPurity:Min. 95%Molecular weight:893.73 g/mol2'-O-Methylguanosine 5'-monophosphate sodium
CAS:2'-O-Methylguanosine 5'-monophosphate sodium is a nucleoside analog that has been shown to inhibit the growth of human cancer cells. It is a modified monophosphate nucleotide, which is synthesized by the chemical modification of guanosine with 2'-O-methylation at the 5' position and phosphorylation at the 3' position. This drug is not active against viruses and may be used as an anticancer agent. 2'-O-Methylguanosine 5'-monophosphate sodium has also been shown to be effective in treating hepatitis B virus infection. The drug may act as an antiviral agent by interfering with viral DNA synthesis, causing viral particles to aggregate, or by inhibiting viral DNA polymerase activity.Purity:Min. 95%5-Cyano-2'-deoxycytidine
CAS:Nucleobase functionalised deoxynucleosideFormula:C10H12N4O4Purity:Min. 95%Molecular weight:252.23 g/mol5'-O-DMT-8-Bromo-N6-(benzoyl)-2′-deoxyadenosine
CAS:Bromo substituted deoxyadenosineFormula:C38H34BrN5O6Molecular weight:736.61 g/mol2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite is a synthetic nucleoside analog. The chemical name for this product is 2'-O-tert-butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-dimethoxytritylguanosine 3'-cyanoethylphosphoramidite. The molecular formula is C28H34N2O8PSi, and the molecular weight is 812.59 g/mol. This product has an EC Number of 61317 - CAS Number of 149989 - 68 - 4 and a melting point of 232°C (238°F). This compound can be used in the synthesis of oligonucleotides that are used to bind to RNA andFormula:C58H76N7O10PSiPurity:Min. 95%Molecular weight:1,090.32 g/mol3'-O-Methylcytidine 5'-triphosphate lithium salt
CAS:3'-O-Methylcytidine 5'-triphosphate lithium salt is an antiviral agent that inhibits the synthesis of RNA by inactivating the enzyme ribonuclease. The compound has been shown to be effective against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). 3'-O-Methylcytidine 5'-triphosphate lithium salt is a novel nucleoside analogue that can be used as a phosphoramidite building block for DNA synthesis. It is also a high quality synthetic product with high purity and high purity.Formula:C10H14N3O14P3·Li4Purity:Min. 95%Molecular weight:520.92 g/mol2’-Deoxy-N2-DMF-2’-fluoroguanosine
Please enquire for more information about 2’-Deoxy-N2-DMF-2’-fluoroguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C13H17FN6O4Purity:Min. 95%Molecular weight:340.31 g/mol2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a novel nucleoside analogue with anticancer activity. It is synthesized from 2'-deoxy-5'-O-DMT-5-acetoxymethyluridine and 3'-chloroethyl phosphate. The compound has been shown to inhibit DNA, RNA, and protein synthesis in vitro, as well as to induce apoptosis in human cancer cell lines. 2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a modified nucleoside that can be used in the production of oligonucleotides for use in gene therapy.Formula:C42H51N4O10PPurity:Min. 95%Molecular weight:802.85 g/molLong trebler phosphoramidite
CAS:Please enquire for more information about Long trebler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C89H107N2O15PMolecular weight:1,475.78 g/mol5'-O-DMT-S6-cyanoethyl-N2-TFA-2'-deoxyguanosine
CAS:Base labile TFA protected deoxyguanosineFormula:C36H33F3N6O6SMolecular weight:734.75 g/mol2'-Amino-2'-deoxycytidine-5'-triphosphate
CAS:2'-Amino-2'-deoxycytidine-5'-triphosphate is an inhibitor of viral RNA polymerase. It is a nucleoside analogue that mimics the natural substrate for the enzyme, 2'-deoxycytidine-5'-triphosphate. This compound binds to the active site of viral RNA polymerases and blocks their ability to synthesize RNA. The compound has been shown to inhibit the replication of norovirus and HIV in cell culture. 2'-Amino-2'-deoxycytidine-5'-triphosphate binds to metal ions in the active site of the enzyme, which prevents its binding with the template strand and prevents elongation of RNA synthesis.Formula:C9H17N4O13P3Purity:Min. 95%Molecular weight:482.17 g/mol2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleoside. This is an anticancer drug that inhibits the growth of cancer cells by inhibiting DNA synthesis and RNA synthesis. It is a novel compound that has been shown to be an activator of cellular proliferation in vitro. 2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is used as a monophosphate nucleoside synthase inhibitor in the treatment of cancer.Formula:C58H76N7O9PSiPurity:Min. 95%Molecular weight:1,074.33 g/mol3'-O-Methyladenosine 5'-triphosphate lithium salt
CAS:3'-O-Methyladenosine 5'-triphosphate lithium salt is a phosphoramidite that is used in the synthesis of DNA and RNA. This product has antiviral and anticancer properties. 3'-O-Methyladenosine 5'-triphosphate lithium salt is a novel nucleoside that is synthesized by modifying the phosphate group with a methyl group at the 3' position. It also has high purity, as well as high quality and modified nucleosides.Formula:C11H14N5O13P3·Li4Purity:Min. 95%Molecular weight:544.94 g/molIDA-dAMP
An iminodiacetic acid phophoramidite. This acts as a pyrophosphate mimic so behaves as a leaving group in the enzymatic polymerisation of deoxyribonucleic acids.Formula:C14H19N6PO9Molecular weight:446.31 g/mol2'-Deoxy-5-methyl-isocytidine
CAS:2'-Deoxy-5-methyl-isocytidine is an analog of cytidine that is used in the synthesis of oligodeoxynucleotides. It has shown to be complementary to dsDNA and to inhibit hepatitis B virus replication in cell culture. 2'-Deoxy-5-methyl-isocytidine is synthesized by solid phase chemistry on a polystyrene support with monomers, depyrimidination, and purification by column chromatography. The chemical stability of this compound has been shown by its ability to withstand heating at 100°C for 10 minutes without decomposition.Formula:C10H15N3O4Purity:Min. 95%Molecular weight:241.26 g/mol3'-Amino-2',3'-dideoxycytidine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics. The lithium salt ensures better handling and solubility.Formula:C9H17N4O12P3(freeacid)Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:466.17 g/molN4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine
CAS:N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine is a boron trifluoride etherate catalyst that catalyzes the synthesis of cytidine from uridine. This catalyst is stable and can be used for many reactions. It yields a trifluoromethanesulfonate as a byproduct. The trifluoromethanesulfonate can be converted to a boronic acid or ester by treatment with base or acid respectively. The etherate can also be converted to an alcohol using hydrogen chloride gas and methanol. N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine has been shown to catalyze the isomerFormula:C28H43N3O7Si2Purity:Min. 95%Color and Shape:PowderMolecular weight:589.83 g/molTrebler phosphoramidite
CAS:Please enquire for more information about Trebler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C86H101N2O14PMolecular weight:1,417.7 g/mol5-(Carboxyhydroxymethyl)uridine methyl ester
CAS:5-(Carboxyhydroxymethyl)uridine methyl ester is a modified form of uridine that is used in biochemical reactions. It is found in the ovary, where it interacts with acidic environments to produce the corresponding hydroxymethyl derivatives. The hydroxymethyl derivatives are then converted to the corresponding 5-carboxy-hydroxymethyl derivatives by conjugates and modifications, which can be analyzed using various assays. 5-(Carboxyhydroxymethyl)uridine methyl ester has also been shown to have epigenetic effects on cellular activity and cancer.Formula:C12H16N2O9Purity:Min. 95 Area-%Color and Shape:Slightly Yellow Clear LiquidMolecular weight:332.26 g/mol2-Methyladenosine-5'-triphosphate
CAS:2-Methyladenosine-5'-triphosphate (2-MeATP) is an inhibitor of the purinergic receptor P2X. It is a competitive antagonist of ATP at the P2X receptor, blocking ATP binding and inhibiting ATP-mediated signal transduction. 2-MeATP has been shown to inhibit angiotensin-mediated hyperpolarization in wild type and mutant strains of M. smegmatis, as well as m. tuberculosis perfusion in mesenteric lymph nodes and vasoconstriction in wildtype and mutant strains of AT1 receptors.Formula:C11H18N5O13P3Purity:Min. 95%Molecular weight:521.21 g/mol3'-Amino-2',3'-dideoxyguanosine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxyguanosine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics. The lithium salt ensures better handling and solubility.Formula:C10H17N6O12P3(freeacid)Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:506.2 g/mol3'-Amino-2',3'-dideoxyadenosine-5'-triphosphate lithium salt - 100 mM aqeous solution
CAS:3'-Amino-2',3'-dideoxycytidine-5'-triphosphate lithium salt is a chain-terminating nucleotide analog for DNA synthesis, similar to ddCTP but with a 3'-amino group. While its role in traditional Sanger sequencing might be limited compared to standard ddCTP, the 3'-amino modification offers potential advantages for specialized sequencing techniques, post-synthetic labeling, and as a research tool to study DNA polymerases. The lithium salt ensures better handling and solubility.Formula:C10H17N6O11P3(freeacid)Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:490.2 g/mol5-Carboxymethyl-2-thiouridine
CAS:5-Carboxymethyl-2-thiouridine is a modified form of uridine that has been synthesized by the reaction of 5-carboxymethyluracil with thiourea. It is used in chemical biology to study protein synthesis and to analyze the structural changes that occur during this process. 5-Carboxymethyl-2-thiouridine has also been shown to be effective as a viral RNA polymerase inhibitor, preventing the synthesis of viral proteins and thus reducing viral replication. This drug is also used in chromatographic methods for separating amino acids, peptides, and proteins.Formula:C11H14N2O7SPurity:Min. 95%Molecular weight:318.3 g/molUDP-N-azidoacetylglucosamine
CAS:UDP-N-azidoacetylglucosamine is a UDP sugar with an azide functional handle on the glucosamine making it suitable for modification via click chemistry.Formula:C17H26N6O17P2Purity:Min. 95%Color and Shape:PowderMolecular weight:648.37 g/mol3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution is the sodium salt of the monophosphate ester of 3'-amino-2',3'-dideoxy-5'-thiacytidine. It is used as an antiviral and antineoplastic agent. 3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution has been shown to be an activator of RNA polymerase II and DNA polymerase, which are enzymes that synthesize proteins and DNA, respectively. This drug also inhibits the synthesis of deoxyribonucleosides, diphosphates, and nucleosides. END>Formula:C10H18N3O13P3(freeacid)Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:481.18 g/molLysidine
CAS:Derivative of cytidine found in tRNA which enhances translation fidelityFormula:C15H25N5O6Purity:Min. 95%Molecular weight:371.39 g/mol5-Carbamoylmethyl-2'-O-methyluridine
CAS:5-Carbamoylmethyl-2'-O-methyluridine is a nucleoside analog that inhibits the synthesis of proteins by inhibiting the translation process. It has been shown to be effective against tuberculosis and other mycobacterial diseases. 5-Carbamoylmethyl-2'-O-methyluridine binds to the ribosomal RNA, preventing protein synthesis and causing cell death. This drug has pleiotropic effects on cells, including inhibition of frameshifting, which is a mechanism used by some viruses to avoid immune responses. 5-Carbamoylmethyl-2'-O-methyluridine also interacts with cellular genes in response to stress (e.g., ultraviolet radiation). The mechanism of action for this drug is similar to that of 5-methoxycarbonylmethyl 2'-thiouridine (5MMCU), which inhibits protein synthesis by binding to the 30S ribosomal subunit and blocking the formation ofFormula:C12H17N3O7Purity:Min. 95%Color and Shape:PowderMolecular weight:315.28 g/mol7-Deaza-3'-deoxyadenosine
CAS:7-Deaza-3'-deoxyadenosine is a synthetic nucleoside that is used in the synthesis of DNA. It has antiviral activity and is effective against HIV, herpes simplex virus and hepatitis B. 7-Deaza-3'-deoxyadenosine also has anticancer activity and can be used as a chemotherapeutic agent for leukemia, lymphoma, and breast cancer. This drug has been shown to inhibit the growth of cultured human tumor cells by inhibiting DNA synthesis through inhibition of DNA polymerase alpha and beta.Formula:C11H14N4O3Purity:Min. 95%Molecular weight:250.25 g/mol[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbomoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbamoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is a novel antiviral agent that is structurally related to the nucleoside analogues. It is synthesized by reacting an N2-(isobutyryl)O6-(diphenylcarbamoyl)guanin with 2,6-bis(trityl)morpholine and methyl dimethyl phosphite in dichloromethane. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), HSV type 2 (HSV2), and cytomegalovirus (CMV). [(2S,6R)-6-{N2-(Isobutyryl)-OFormula:C48H48ClN8O6PPurity:Min. 95%Molecular weight:899.37 g/mol5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Formula:C9H14N4O5Purity:95%Color and Shape:SolidMolecular weight:258.23135'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside that can be used as an antiviral and anticancer agent. It has shown to be more potent than other nucleosides in inhibiting the synthesis of viral DNA and RNA, which makes it a potential candidate for treating HIV infection and cancer. This drug can also act as an activator by stimulating the production of deoxyribonucleotides and ribonucleotides. 5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine has been shown to have high purity and quality, making it a good candidate for use in various fields of research.
Formula:C11H13F2N3O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:305.23 g/molRef: 3D-NA10690
Discontinued productN6-Benzoyl-2'-O-(2-methoxyethyl)adenosine
CAS:N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.
Formula:C20H23N5O6Purity:Min. 95%Molecular weight:429.43 g/mol
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