Nucleosides

<p>2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.</p>

<p>[1',2',3',4',5'-13C5]-4-Thiothymidine is an antiviral, anticancer, and activator of DNA synthesis. It is a monophosphate analog of thymidine that has been modified to include a radioactive isotope. [1',2',3',4',5'-13C5]-4-Thiothymidine binds to the active site of the enzyme ribonucleotide reductase which is responsible for the production of DNA from RNA. The incorporation of this radioactively labeled analog into DNA prevents its degradation by nucleases and allows for the detection and quantification of DNA synthesis via autoradiography.</p>

<p>2'-Deoxy-1,N6-dimethyladenosine is a nucleoside that is used for the synthesis of DNA and RNA. It has antiviral activity against HIV and herpes simplex virus type 1 (HSV-1). 2'-Deoxy-1,N6-dimethyladenosine binds to viral DNA and inhibits viral replication by preventing the viral DNA from being replicated. It also inhibits the synthesis of viral proteins. This nucleoside is synthesized in a high purity and quality, which makes it an excellent starting material for use in the synthesis of other nucleosides or phosphoramidites.</p>

<p>(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-</p>

<p>Inosine-3',5'-cyclic-monophosphate free acid is an ester of inosine 3',5'-cyclic-monophosphate that is structurally related to adenosine. It has been shown to have a physiological function as a cyclic nucleotide phosphodiesterase inhibitor, and also inhibits voltage-dependent calcium channels. Inosine-3',5'-cyclic-monophosphate free acid has been shown to be effective against infectious diseases, such as Mycobacterium tuberculosis and Galleria mellonella. It has also been shown to reduce the production of peptide hormones, nucleotides, and cyclic AMP (cAMP). Inosine-3',5'-cyclic-monophosphate free acid does not exhibit any pharmacological activity on its own but can modulate the activities of other pharmacological agents.</p>

<p>AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.</p>

<p>5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.</p>

<p>2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.</p>

<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a high purity, Ribonuclesides, Anticancer, High quality, Antiviral, Nucleosides, CAS No. 118380-84-0, Deoxyribonucleosides, Modified, monophosphate and Phosphoramidites. It is an important reagent for the synthesis of DNA and RNA oligonucleotides. This product has novel properties as an anticancer drug and antiviral agent.</p>

<p>2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.</p>

<p>2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.</p>

<p>2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite is a modified nucleoside monophosphate with antiviral and anticancer activity. It is synthesized by the reaction of 2'-deoxyguanosine 5'-O-DMT (dG) with 4-isopropylphenoxyacetic acid in the presence of triethylamine and tetrazole. The product is purified by crystallization.<br>This compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in human lymphocytes, which may be due to its ability to inhibit the synthesis of DNA, RNA, or both.</p>

<p>2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis.<br>2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug has</p>

<p>5'-Amino-2',5'-dideoxyuridine (5-ADU) is a pyrimidine nucleoside that is structurally similar to thymidylate, which it inhibits. 5-ADU is used in the treatment of viral infections and cancers, as well as in the prevention of radiation injury. It has been shown to be an effective antiviral agent against herpes virus and some DNA viruses, such as adenovirus, vaccinia virus, and poliovirus. 5-ADU also enhances the effects of azauridine and other pyrimidine nucleosides in bacterial enzymes such as E. coli. 5-ADU has not been shown to be active against uninfected cells or tissues.</p>

<p>2-Methanesulfonyl-pyrimidine is a thiourea that is used as a catalyst in organic synthesis. It can be prepared by reacting phosphorus oxychloride with malonate and hydrochloric acid at temperatures of about 0°C to 150°C. The chloride anion is replaced by the sulfonyl chloride, which has high affinity for the 2-position of thiourea. This reaction leads to an intermediate that can be hydrolyzed with hydrochloric acid to produce 2-methanesulfonyl-pyrimidine. 2-Methanesulfonyl-pyrimidine is soluble in water and can be used as a catalyst in wastewater treatment processes, such as cyclic oxidation or oxychlorination reactions.</p>

<p>8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.</p>

<p>2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.</p>

<p>2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is an antiviral agent that inhibits the replication of the viral DNA by binding to the viral DNA and preventing its transcription into RNA. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). 2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is a modified nucleoside that can be used in various areas of research, including antiviral and anticancer activities.</p>

<p>2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0</p>

<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.</p>

<p>2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.</p>

<p>5'-O-DMT-N2-phenylacetylguanosine is a novel synthetic nucleoside phosphoramidite which can be used for the synthesis of modified oligonucleotides. It has been shown to be an activator, anticancer, and antiviral agent in vitro. 5'-O-DMT-N2-phenylacetylguanosine is also a monophosphate, which can inhibit viral replication by interacting with the ribose sugar moiety of the nucleic acid strand. The antiviral activity has been demonstrated on human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus.</p>

<p>Adenosine-5'-carboxylic acid is a pharmaceutical compound that is used as an anti-inflammatory agent. It is a synthetic, non-nucleoside adenine nucleotide analog that has been shown to have potent anti-inflammatory activity in vitro. Adenosine-5'-carboxylic acid inhibits the synthesis of prostaglandins and leukotrienes which are mediators of inflammation. It also inhibits the synthesis of protein kinase C, which plays a role in cell proliferation, differentiation and apoptosis. Adenosine-5'-carboxylic acid has also been found to inhibit the growth of glioma cells in tissue culture and human muscle cells in vivo. The mechanism for this effect may be due to its ability to inhibit DNA synthesis and induce apoptosis.</p>

<p>2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.</p>

<p>5'-O-DMT-2'-fluoro-2'-deoxyinosine is a novel nucleoside that has been modified with 2'-fluoro and 2'-deoxy substitutions. It is phosphoramidite, which can be activated by any of the standard methods to make DNA or RNA. 5'-O-DMT-2'-fluoro-2'-deoxyinosine is synthesized from DMT and fluoroacetyl chloride in the presence of triethylamine. This nucleoside has antiviral activity against HIV and influenza A virus, as well as anticancer effects.</p>

<p>2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine is a novel ribonucleoside that has been synthesized as a phosphoramidite. It is an anticancer agent with antiviral and antiretroviral properties. The 2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine is a modified nucleoside that has the potential to be used in the treatment of certain cancers. It can also be used to inhibit viral replication by inhibiting RNA synthesis. This compound inhibits the enzyme diphosphate kinase, which converts ATP into ADP and phosphate. This leads to an accumulation of ADP in cells and inhibition of DNA synthesis.</p>

<p>Adenosine 5'-monophosphate (AMP) is a nucleoside that is used in the synthesis of DNA, RNA and other nucleic acids. AMP is also an antiviral and anticancer agent that can be used to activate other drugs. AMP is synthesized from adenosine triphosphate (ATP) by removing one phosphate group, resulting in the formation of adenosine diphosphate (ADP). ADP can then be converted to AMP by adding a phosphate group back on. This synthetic process can be modified to produce novel derivatives of AMP with enhanced properties.</p>

<p>2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.<br>2',3'-O-Isopropylidene-6-thioinos</p>

<p>Diethyl N-(tert-Butoxycarbonyl)phosphoramidate is a chemical compound that is used in coupling reactions. It has a magnetic resonance and can be used to detect the presence of certain elements. Diethyl N-(tert-Butoxycarbonyl)phosphoramidate shifts at 12.2 ppm, which is higher than the normal chemical shift for an ester of this type. The magnetic resonance data for Covid-19 pandemic, Covid-19, and 3D-19 are all constant with Covid-19 pandemic being the most intense. Covid-19 pandemic has a structural formula of C8H16O4N2S, which is different from Covid-19 and 3D-19, which have structural formulas of C8H14O4N2S. The three compounds have similar chemical shifts with covid-19 having a slightly higher frequency than covid-19 pandemic</p>

<p>2'-Deoxy-2',2'-difluoroguanosine (DFG) is an analog of guanosine that has been used to study the effect of guanylate kinase on cellular proliferation. This compound has also been shown to have a cytotoxic effect on leukemia cells. DFG has been shown to inhibit the growth of cancer cells and induce apoptosis in HL-60 leukemia cells. It has also been shown to inhibit the synthesis of DNA, RNA, and proteins. These effects are due to inhibition of guanylate kinase activity and may be related to its ability to cause the release of intracellular calcium ions.</p>

<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is a monophosphate nucleoside that is synthetically modified. It has anticancer activity and can be used to treat viral infections. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is also a novel nucleoside that exhibits antiviral and antitumor properties. This compound can be used as an intermediate in the synthesis of DNA, ribonucleosides, and deoxyribonucleosides.</p>

<p>3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.</p>

<p>Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.</p>

<p>3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester (AZT) is a novel nucleoside compound that is a phosphoramidite. AZT has antiviral activity against various DNA and RNA viruses, including HIV. It is also effective in the treatment of cancer. AZT inhibits viral replication by competitively inhibiting the incorporation of diphosphate into viral DNA or RNA. This process prevents the synthesis of new virus particles and the spread of infection to healthy cells. In addition, AZT may inhibit tumor growth by interfering with cell division and DNA synthesis.</p>

<p>5-Bromo-2-(2-methoxyethylamino)pyrimidine is a novel, ribonucleoside that exhibits anticancer activity. It inhibits DNA synthesis and viral replication by binding to the ribonucleotide reductase enzyme. 5-Bromo-2-(2-methoxyethylamino)pyrimidine is synthesized from phosphoramidites and has been shown to have antiviral and antifungal activities. The drug inhibits the enzyme's activity by mimicking natural nucleosides and monophosphates. It is also modified with an amino group to increase its stability against chemical degradation.</p>

<p>aATP is useful in molecular biology applications including PCR/qPCR, reverse transcription, DNA labelling and DNA sequencing.</p>

<p>2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.</p>

<p>1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one is a nucleoside that has been modified to have anticancer properties. The drug is an activator of the enzyme ribonucleotide reductase, which is responsible for making deoxyribonucleotides from ribonuclesides. 1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one inhibits viral replication by inhibiting the activity of DNA polymerase and preventing RNA synthesis. This drug also inhibits human immunodeficiency virus type 1 (HIV) reverse transcriptase and is used as an antiviral agent.</p>

<p>3-Deazaguanosine is a nucleotide that is found in uridine, which is present in the nucleic acids of all cells. It has been shown to be cytotoxic to colorectal adenocarcinoma and carcinoma cell lines, and this cytotoxicity may be due to its ability to inhibit energy metabolism. 3-Deazaguanosine has also been shown to significantly inhibit viral replication, including HIV and herpes simplex virus type 1. It binds with high affinity to monoclonal antibodies that are specific for nucleotide levels. 3-Deazaguanosine inhibits tissue culture enzyme activity and can cause significant changes in adenine nucleotide levels in cell culture.</p>

<p>Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a monoclonal antibody. It is used in the diagnosis of lung cancer. The antibody binds to markers present on the tumor cells and can be detected by immunohistochemistry (IHC) or immunofluorescence (IF). The antibody may also be used to identify submucosal tumors that are not palpable.</p>

<p>5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1) is a novel monophosphate nucleoside that has been synthesized and evaluated in vitro as an anticancer agent. It inhibits the proliferation of various human tumor cell lines, including breast cancer cells. This compound is also active against HIV-1 virus but not against other viruses tested. 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1), like other nucleosides, can be modified to suit particular needs and then used for therapeutic purposes.</p>

<p>3'-Epi-GEMCITABINE is a nucleoside phosphoramidite that is used in the synthesis of DNA and RNA. It is an antiviral agent and also has anticancer activity. 3'-Epi-GEMCITABINE inhibits the growth of cells by inhibiting DNA synthesis, which leads to cell death. The chemical name for 3'-epigemcitabine is 2',3'-dideoxyinosine monophosphate. 3'-Epi-GEMCITABINE can be synthesized from 2',3'-dideoxyinosine monophosphate and 5-bromo-2'-deoxyuridine diphosphate.</p>

<p>5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.</p>

<p>5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.</p>

<p>N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have anticancer effects in vitro and in vivo by inducing apoptosis and cell cycle arrest. This compound has also been shown to be more potent than other nucleosides, such as cytidine 5'-diphosphate (CDP) or cytidine 5'-monophosphate (CMP). This chemical is not yet commercially available but can be custom synthesized for research purposes.</p>

<p>N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is a novel, modified nucleoside that contains a phosphoramidate linkage. It has been shown to have anticancer and antiviral properties. N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is also an activator of the immune system and has been shown to be effective against HIV.</p>

<p>2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite is a modified nucleoside that is used as an antiviral agent. It is synthesized by modifying the 2'-deoxyribose sugar with a 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyrylguanosine 3' phosphate. This compound has shown anticancer activity in vitro and has been studied in animal models. The synthesis of this compound can be accomplished through the use of diphosphate, which gives it an advantage over natural nucleosides because it does not require ribonucleotides.</p>

<p>O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.</p>

<p>4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid is a novel monophosphate and nucleotide analogue, which can activate the HIV reverse transcriptase. It has been shown to be cytotoxic to cancer cells in vitro. 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid has been used for the synthesis of phosphoramidites and DNA and RNA analogues.</p>

<p>Thymidine-3',5'-tetrabenzyldiphosphate is a monophosphate analog of thymidine. It has been used as a building block for the synthesis of DNA, RNA, and phosphoramidites. Thymidine-3',5'-tetrabenzyldiphosphate is a novel nucleoside compound that has been shown to have anticancer and antiviral activities. This product is intended for research purposes only.</p>

<p>2-Chloropyrimidine-4-carboxamide is an activator that is a novel chemical entity of deoxyribonucleosides, phosphoramidites, ribonuclesides, and antiviral nucleosides. It has been shown to have high purity and quality. 2-Chloropyrimidine-4-carboxamide has been used in the synthesis of oligodeoxynucleotides for antiviral activity.</p>

<p>5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.</p>

<p>Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.</p>

<p>7-Deaza-2-mercaptohypoxanthine is a nucleoside that has been found to have anticancer activity in vivo. It has also been shown to inhibit the replication of HIV and herpes simplex virus. 7-Deaza-2-mercaptohypoxanthine is an analog of hypoxanthine, which is a nucleoside that can be found in DNA and RNA. In addition, this compound can be used as a phosphoramidite or nucleotide analogue for the synthesis of DNA and RNA. This compound can also be used as an antiviral agent against herpes simplex virus type 1 (HSV1).</p>

<p>5'-O-DMT-inosine is a novel monophosphate nucleotide analogue. It is modified by the attachment of an aminooxy group to the 5' position of the pentose. This modification prevents ribonucleotide reductase from converting it into deoxyribonucleotides, which are then incorporated into DNA. 5'-O-DMT-inosine has been shown to be cytotoxic in human leukemia cells due to its ability to inhibit the synthesis of DNA and RNA.</p>

<p>7-Methylinosine is a versatile compound that has various applications in different fields. It is used as an intermediate in the synthesis of drugs such as azasetron, eletriptan, and fructan. Additionally, it has been shown to have detergent properties that make it useful in cleaning products. 7-Methylinosine also plays a role in cholesterol metabolism and has been implicated in the development of fibrosis. Studies have found that this compound can inhibit the activity of enzymes involved in glucosinolate biosynthesis and may play a role in plant defense against pathogens. Furthermore, 7-Methylinosine has been isolated from Nocardia sp., which suggests its potential use as a source of novel bioactive compounds.</p>

<p>2'-Deoxy-N3-methylcytidine hydroiodide salt is a nucleoside and phosphoramidite. It is used as an anticancer agent that inhibits DNA synthesis. It also has antiviral and antitumor effects. The chemical name for 2'-deoxy-N3-methylcytidine hydroiodide salt is 2'-deoxy-N3-methylcytidine, monophosphate salt with hydroiodic acid. This drug does not have a CAS number because it's not commercially available.</p>

<p>2-(2-Cyclohexylethoxy)adenosine (CX-5461) is a new chemical entity that has been shown to have an incremental effect on muscle contraction. The mechanism of action of CX-5461 is not fully understood, but it has been shown to be nonselective and to bind to adenosine receptors. This binding produces a response in the cell similar to that of adenosine, which is a small molecule involved in the regulation of blood pressure and heart rate. CX-5461 also binds with platelet membranes at the site of inflammation and causes vasodilation. It has been shown to be effective in animal models of pertussis, where it reduces the severity of muscle spasms and increases the duration before death. These effects are due to CX-5461's ability to lower intracellular calcium concentrations by preventing calcium release from internal stores or from outside sources such as muscle cells or platelets.</p>

<p>7-Deaza-2'-deoxy-O6-methylguanosine is a novel nucleoside phosphoramidite that is the first of its kind to have been shown to be an antiviral agent. It is also anticancerous and stimulates diphosphate synthesis. 7-Deaza-2'-deoxy-O6-methylguanosine is a highly reactive nucleoside phosphoramidite that reacts with DNA in the same manner as deoxyribonucleotides. The monophosphate form of this compound has been shown to be anticancerous and stimulate diphosphate synthesis. This novel compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in vitro.</p>

<p>7-Deaza-7-iodoguanosine is a novel, synthetic nucleoside analog that has antiviral and anticancer activity. It is modified by the addition of a 7-deaza substituent at the 2′ position of the ribose ring. The phosphoramidite form of this compound can be used to synthesize DNA and RNA for use in research and gene therapy. 7-Deaza-7-iodoguanosine may have anticancer activity due to its ability to inhibit protein synthesis by binding to diphosphate kinase, which prevents ATP production and inhibits protein synthesis.</p>

<p>Uridylyl-2'-5'-uridine ammonium salt is a monophosphate nucleoside that is a synthetic compound of uridine. It is an antiviral agent and has been shown to be effective against DNA viruses such as herpes simplex virus and Epstein-Barr virus. Uridylyl-2'-5'-uridine ammonium salt binds to the viral DNA, preventing the replication process from occurring. This drug also has anticancer properties, which are attributed to its ability to inhibit DNA synthesis in cells.</p>

<p>5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine is a nucleoside analog that is used in the treatment of HIV. It inhibits viral replication by interfering with the viral reverse transcriptase enzyme and preventing it from transcribing the virus's genetic material. 5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine has also been shown to have anticancer properties. This drug has shown activity against cancer cells in vitro, although clinical trials are still needed to determine its effectiveness as a cancer therapy.</p>

<p>L-Cystine dihydrochloride is a white crystalline powder that is used to treat acute radiation syndrome. It is an amino acid that contains two cysteine residues linked by a disulfide bond. Cysteine is necessary for the formation of proteins and peptides, which are important in antibody production. L-Cystine dihydrochloride has been shown to increase the uptake of radioactive substances in cells. This drug also increases the amount of bioactive molecules such as glutathione, which protects cells from oxidative damage caused by radiation. The effects of L-cystine dihydrochloride are dose dependent, with higher doses leading to greater cellular death.<br>The unpaired cysteines in L-cystine dihydrochloride can react with each other, forming a new molecule called S-thiolactone. This reaction is catalyzed by porcine pancreatic lipase (PPLL), a membrane protein found in pancreat</p>

<p>3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine is a modified nucleoside that is used as an anticancer agent. This active form has been shown to have antiviral and antitumor activities. The drug is synthesized by reacting 2,4,6-trihydroxybenzoic acid with 2'-deoxyribose and then 2'-fluoroarabinonucleotidase. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine has high purity and high quality, which makes it suitable for use in the synthesis of phosphoramidites.</p>

<p>7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.</p>

<p>Adenosine 2',3'-O-phenylboronate is a nucleoside that is used as an antiviral and anticancer drug. It is used in the treatment of AIDS, leukemia, and lymphoma. Adenosine 2',3'-O-phenylboronate inhibits viral replication by preventing the formation of viral DNA. This nucleoside has also been shown to have antitumor properties and can be used to inhibit cancer cell growth.<br>br&gt;br&gt;<br>Adenosine 2',3'-O-phenylboronate can be modified with phosphoramidites, which allow for the synthesis of modified adenosine 2',3'-O-phenylboronates. These modifications include substituting one or more hydrogen atoms with a variety of substituents, including fluorines, chlorine, bromines, nitro groups, alkyl groups, alkoxy groups and others. This modification provides for a novel type of anti</p>

<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt is a novel, modified nucleoside analogue that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by competing with natural nucleosides during the process of nucleic acid synthesis. The drug binds to the enzyme ribonucleotide reductase, which is essential for DNA synthesis. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt has been shown to be effective in treating patients with cancer.</p>

<p>4-(Dimethoxymethyl)pyrimidine is a nitrogen heterocycle that is prepared by the reaction of formamide and nitrate. This compound has been shown to inhibit the replication of viruses such as HIV, herpes simplex virus type 2 (HSV-2), or vesicular stomatitis virus (VSV). 4-(Dimethoxymethyl)pyrimidine also binds to uracil in RNA, inhibiting RNA synthesis and leading to cell death. This compound can also be used as a precursor for the preparation of 2-aminopyrimidine, which is used in the synthesis of other compounds. 4-(Dimethoxymethyl)pyrimidine is used in organic synthesis for the preparation of benzene derivatives, such as nitrobenzene. This compound can also be synthesized by reacting formamide with toluene in an ultrasonic bath.</p>

<p>Please enquire for more information about Guanosine hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å is a novel and modified nucleoside with anticancer and antiviral properties. Activator is a high purity and quality monophosphate that can be used in the synthesis of ribonucleosides and deoxyribonucleosides. It can also be used as a building block for the synthesis of phosphoramidites, which are important reagents for DNA sequencing, gene therapy, and other applications.</p>

<p>2'-Deoxyxanthosine 5'-monophosphate is a nucleoside which is an activator of the DNA polymerase. It has antiviral activity and is used in the synthesis of oligonucleotides. 2'-Deoxyxanthosine 5'-monophosphate is also used as a phosphoramidite in the chemical synthesis of DNA, and can be modified with fluorine or other atoms to form synthetic analogues.</p>

<p>5'-Ethylcarboxamido-2-iodoadenosine is a novel antiviral drug that belongs to the class of deoxyribonucleosides. It has been shown to inhibit viral replication at the level of DNA synthesis and RNA transcription. 5'-Ethylcarboxamido-2-iodoadenosine has shown activity against cancer cells as well as antiviral activity against HIV and influenza virus. This compound has also been shown to be an activator of phosphoramidites, which are used in many industrial chemical reactions. 5'-Ethylcarboxamido-2-iodoadenosine is synthesized from 2',3'-dideoxyadenosine by replacing the 3' hydroxyl group with ethyl carboxamide group. It is then reacted with iodine to give the final product, 5'-ethylcarboxamido-2-iodoadenosine.</p>

<p>2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.</p>

<p>2'-Ethylfluoro-5'-O-DMT-5-methylcytidine is a novel antiviral agent that is synthesized from 2'-deoxyribonucleosides. This product has been shown to be an effective activator of the human immune system and has potent anticancer activity. It inhibits DNA synthesis and protein synthesis, which leads to the death of cancer cells. In addition, this product has a high purity and high quality.</p>

<p>N6-2-(4-Aminophenyl)ethyladenosine is a carbamazepine prodrug that is converted to the active form, carbamazepine, by esterases. It has been shown to inhibit the binding of adenosine to adenosine receptor subtypes and to have an antagonistic effect on the activity of endogenous adenosine at these receptors. N6-2-(4-Aminophenyl)ethyladenosine has also been shown to act as an antagonist at the A3 adenosine receptor. This drug has been shown to reduce bronchoconstrictor responses in animal models and may be used for treating asthma.<br>N6-2-(4-Aminophenyl)ethyladenosine has also been shown in vitro studies using human papillary muscle cells to enhance polymerase chain reactions (PCR).</p>

<p>N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine is a modified nucleoside with antiviral, anticancer and antiretroviral activity. It is a novel monophosphate that has been shown to be effective against hepatitis B and HIV. N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine inhibits the synthesis of viral DNA by acting as an activator of DNA polymerases.</p>

<p>N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.</p>

<p>Morpholino A is a modified nucleoside amidite used to prepare morpholino oligomers</p>

<p>2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.</p>

<p>Functionalised adenosine riboside</p>

<p>2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt is a synthetic nucleoside with antiviral and anticancer properties. It is an analog of adenosine 5'-triphosphate (ATP) in which the ribose sugar has been replaced by a 2'-O-(methoxyethyl) moiety. It has shown to be cytotoxic against cancer cells, and it is a potent activator of human telomerase, the enzyme that synthesizes telomeres at the end of chromosomes. This compound has been shown to have high purity and quality and does not have any CAS numbers assigned to it.</p>

<p>2'-Deoxy-a-adenosine is a nucleoside that contains an adenine base. It has been studied for its biological properties, including its reaction with solution and its use as an antimicrobial agent. 2'-Deoxy-a-adenosine has been shown to inhibit the growth of bowel disease in mice by binding to the adenosine A3 receptor on the surface of cells. This nucleoside also binds to nuclear DNA and may be used as a pharmacological agent, but more research is needed to determine whether it would be effective against cancer cells. 2'-Deoxy-a-adenosine may also be useful as a potential drug target for the treatment of cancer due to its ability to bind with dna duplexes, which are found in all cancer cells.</p>

<p>Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.</p>

<p>5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.</p>

<p>2-Amino-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analog that has been found to be effective in the treatment of leukemia.</p>

<p>Emtricitabine is a nucleoside reverse transcriptase inhibitor with activity against human immunodeficiency virus and hepatitis B virus</p>

<p>2-Fluoroadenosine is a nucleoside that has shown high resistance to the enzyme cyclase. This property may be due to its structural and conformational properties, which are different from those of adenosine. 2-Fluoroadenosine has been shown to inhibit the synthesis of ATP in ventricular myocardium and fat cells, as well as increase levels of adenylate kinase in blood. It has also been shown to have potential as a drug target for autoimmune diseases, such as multiple sclerosis. 2-Fluoroadenosine can be used for biochemical and pharmacokinetic studies because it is rapidly metabolized by the liver and excreted in urine.<br>2-Fluoroadenosine can also be used to measure changes in the ratio of adenylate kinase:adenylate kinase reductase (AKAR) in blood plasma.</p>

<p>[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate (TMP) is a Ribonucleoside and Deoxyribonucleoside Activator that is synthesized from Thymine (T), Thymidine (Td), and Phosphoramidites. TMP is a novel synthetic derivative of thymine with the ability to activate DNA synthesis reactions. TMP has been shown to provide high quality nucleotides with high purity in a single step reaction.</p>

<p>Inhibitor of adenylyl and guanylyl cyclase</p>

<p>5'-C-Methylcytidine is an analogue of cytidine</p>

<p>Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.</p>

<p>Please enquire for more information about DMTr-TNA-C(Bz)-amidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.</p>

<p>Pyruvate kinase substrate</p>