Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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2'-Deoxyguanosine 3'-O-L-valinyl ester
2'-Deoxyguanosine 3'-O-L-valinyl ester is a synthetic nucleoside obtained from 2'-deoxyguanosine and valine. It has antiviral activity against DNA viruses, such as herpes simplex virus and vaccinia virus, and anticancer activity. 2'-Deoxyguanosine 3'-O-L-valinyl ester is an analog of guanosine that has been modified to contain an L-valyl group at the 3' position. This modification increases the stability of this nucleoside in aqueous solutions and provides potent antiviral and anticancer activity.Purity:Min. 95%5-Hydroxymethylcytidine
CAS:5-Hydroxymethylcytidine is a nucleoside that has been shown to inhibit the activity of RNA polymerase by forming hydrogen bonds with the enzyme. It is used in vitro to study the role of messenger RNA in regulating gene expression, and also as a probe for transcriptase activity. 5-Hydroxymethylcytidine has also been shown to have a biological function in solid tumours and may be an analytical method for detecting cancer.Formula:C10H15N3O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:273.24 g/molN4-Acetyl-3'-deoxy-3'-C-methylcytidine
N4-Acetyl-3'-deoxy-3'-C-methylcytidine is a novel antiviral drug that is modified from cytidine. It is an activator of the monophosphate pathway of DNA synthesis, which causes the incorporation of N4-acetyl-3'-deoxy-3'-C-methylcytidine into ribonucleosides and deoxyribonucleosides. This compound has been shown to be active against a variety of cancers, including leukemia, colon cancer, breast cancer, and prostate cancer.Formula:C12H17N3O5Purity:Min. 95%Molecular weight:283.28 g/mol2',3'-Dideoxyinosine
CAS:2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversionFormula:C10H12N4O3Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:236.23 g/mol5'-O-Pixylthymidine
5'-O-Pixylthymidine is a modified nucleoside that has been shown to have anticancer and antiviral activity. It is an analog of thymidine, which is a deoxynucleoside. 5'-O-Pixylthymidine can be converted into diphosphate form by addition of phosphoramidites or ribonucleosides. This nucleotide can also be used as a building block for the synthesis of oligonucleotides, which are synthetic DNA molecules with therapeutic applications.Formula:C29H26N2O6Purity:Min. 95%Molecular weight:498.53 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS:2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applicationsFormula:C15H20ClN5O4H2OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:378.81 g/mol8-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.Formula:C10H13N5O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:283.25 g/molN6-Benzyladenosine 5'-monophosphate sodium salt monohydrate
CAS:N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.
Formula:C17H18N5Na2O7P·H2OPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:499.32 g/mol3'-O-Methylguanosine 5'-triphosphate lithium
CAS:3'-O-Methylguanosine 5'-triphosphate lithium is a nucleotide that has been synthesized and characterized. It is a biochemical regulatory molecule that is involved in the synthesis of DNA, RNA, and proteins. 3'-O-Methylguanosine 5'-triphosphate lithium binds to the guanine nucleotide binding protein G, which acts as an allosteric activator of the enzyme ribonucleotide reductase. The reconstituted enzyme system containing 3'-O-methylguanosine 5'-triphosphate lithium has demonstrated a high level of fidelity in the replication of dna templates.
Formula:C11H18N5O14P3•Li4Purity:Min. 95%Color and Shape:PowderMolecular weight:564.97 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is a novel modified nucleoside. It is an antiviral and anticancer agent that has been shown to inhibit the replication of DNA in vitro. It also inhibits the synthesis of RNA and protein, which may contribute to its anti-cancer properties. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is synthesized from 2,6,8 trichloroquinoline and 2,3,4 trimethoxybenzaldehyde via a novel process with high purity.Formula:C51H62N7O6PSiPurity:Min. 95%Molecular weight:928.17 g/mol3'-O-Methyl-5-methylcytidine
CAS:3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.Formula:C11H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:271.27 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFormula:C38H52N5O8PSiPurity:Min. 95%Molecular weight:765.93 g/mol6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.Purity:Min. 95%2-Chloro-2',3'-O-isopropylideneadenosine
CAS:2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.Formula:C13H16ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:341.75 g/molBBQ-650-DT CEP
CAS:BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.Formula:C76H89N12O15PPurity:Min. 95%Molecular weight:1,441.6 g/mol8-Bromoinosine
CAS:8-Bromoinosine is a potent chemical probe that can be used to study the molecular mechanism of cGMP-dependent protein kinase (PKG). 8-Bromoinosine reacts with the acceptor site in PKG, which is located at the base of the active site cleft. Electrons from hydrogen bond donor sites on 8-bromoadenosine are transferred to chloride ion and the resulting 8-bromoinosine chloride complex is an effective inhibitor of PKG. It has been shown that stereoselectivity plays a role in this reaction mechanism.
Formula:C10H11BrN4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:347.13 g/mol2'-Deoxy-2'-fluoroadenosine
CAS:2’-Deoxy-2’-fluoro nucleosides and nucleotides have been shown to demonstrate anti-viral activity against influenza, SARS and HIV. More specifically the phosphonate of 2'-Deoxy-2'-fluoroadenosine has been evaluated as an inhibitor of Hepacivirus C (HCV).Formula:C10H12FN5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:269.24 g/mol6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine
CAS:6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to be an efficient activator of the transcription factor NFκB in vitro. 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is synthesized by phosphoramidite chemistry and purified by HPLC. It has been demonstrated to inhibit the replication of human immunodeficiency virus (HIV) in a dose dependent manner, which may be due to its ability to inhibit the synthesis of viral DNA and RNA. This product is highly pure and can be used for many purposes, including as a synthetic building block for DNA or as an antiviral drug.Formula:C11H12ClN3O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.69 g/mol5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine
5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine is a compound that inhibits DNA synthesis and viral replication. It is an antiviral agent that inhibits the activation of virus by blocking the incorporation of deoxyribonucleotide triphosphates into viral DNA chains. This compound also has anticancer activity, which may be due to its ability to inhibit RNA synthesis in tumor cells.Formula:C17H17N5O6Purity:Min. 95%Molecular weight:387.35 g/mol2,3'-Anhydrouridine 5'-CE phosphoramidite
2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.Formula:C18H27N4O6PPurity:Min. 95%Molecular weight:426.41 g/mol
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