
Nucleosides
Found 3569 products of "Nucleosides"
5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a novel nucleoside and phosphoramidite activator. It is synthesized from 2'-deoxyadenosine, 5'-chloropurine riboside, and 1,1'-bis(diisopropylphosphino)ferrocene. This compound has been shown to be an effective antiviral and anticancer agent in vitro.Formula:C12H15ClN4O4Purity:Min. 95%Molecular weight:314.72 g/mol7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine
CAS:7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine is a novel modified ribonucleoside. It has the ability to activate DNA at the monophosphate level and can be used as a substrate for DNA polymerase and in the synthesis of deoxyribonucleosides. 7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine also has antiviral properties, which may be due to its inhibition of viral RNA synthesis. The compound is also used in anticancer treatment as it inhibits cellular proliferation by inhibiting DNA synthesis.
Purity:Min. 95%5'-O-tert-Butyldimethylsilyl-2'-deoxyuridine
5'-O-tert-Butyldimethylsilyl-2'-deoxyuridine (5'-O-TBDMSU) is a modified nucleoside that has antiviral, anticancer and novel activities. It is synthesized by the reaction of 5'-O-tert-butyldimethylsilyl-2'-deoxyuridine with methyl chloroformate. 5'-O-TBDMSU has been shown to inhibit viral replication in cell culture. The antiviral activity of 5'-O-TBDMSU may be due to its ability to inhibit DNA synthesis by inhibiting the incorporation of deoxyribonucleotide triphosphates into DNA or by inhibiting the activity of DNA polymerases. This compound also inhibits the replication of RNA viruses such as HIV and hepatitis C virus, which are dependent on deoxyribonucleosides for their replication.Formula:C15H26N2O5SiPurity:Min. 95%Molecular weight:342.47 g/mol5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine
5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine is a novel nucleoside that is synthesized from ribonucleosides. It is an inhibitor of the RNA polymerase enzyme, which prevents the transcription and replication of DNA. 5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine also inhibits viral DNA synthesis by preventing viral RNA from being translated into DNA. This product has been shown to be active against a wide range of viruses, including influenza A virus, herpes simplex virus type 1, and vaccinia virus.Formula:C16H15FN2O5Purity:Min. 95%Molecular weight:334.35 g/mol3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine
3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel antiviral drug with anticancer properties. This active compound has been shown to be an activator of ribonucleotide reductases, which are enzymes that catalyze the conversion of ribonucleotides to deoxyribonucleotides. 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is not cytotoxic at concentrations up to 40 mM, and it has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV) in tissue culture.Purity:Min. 95%1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine is a deoxyribonucleoside monophosphate with antiviral effects. It is a novel nucleotide analogue that contains an azido group and a 2,4,6-trifluorobenzene moiety. The 4′ position of the sugar is modified with an n-docosanoyl group. 1-(4’Azo-2′deoxy-2′fluoro-bDara)ribonucleosides are synthetic nucleotides that can be used to inhibit viral replication by inhibiting DNA polymerase and RNA polymerase.Purity:Min. 95%5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.Formula:C39H47N4O9PPurity:Min. 95%Molecular weight:746.79 g/mol8-Azidoadenosine
CAS:8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.
Formula:C10H12N8O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.25 g/mol2',3'-Dideoxy-5-methylcytidine
CAS:2',3'-Dideoxy-5-methylcytidine is a synthetic nucleoside analog based on cytidine, a natural building block of DNA and RNA. This molecule is chemically modified to interfere with nucleic acid synthesis, making it a potential tool in antiviral or anticancer therapy, or for studying epigenetics.Formula:C10H15N3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:225.25 g/molN2,N2,7-Trimethylguanosine
CAS:Trimethylguanosine is a hydrogen-bonded base that is found in the DNA of all living organisms. It has a diagnostic role in cancer and metabolic disorders, as well as in the study of cell culture. Trimethylguanosine can be used to identify cancer cells by measuring its fluorescence properties, which are different from those of healthy cells. This compound also has a role in the diagnosis of metabolic disorders, such as diabetes mellitus and renal disease. Trimethylguanosine is also involved in biological function, and is necessary for the synthesis of proteins and nucleic acids.Formula:C13H20N5O5Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:326.33 g/molAdenine
CAS:Adenine is a nucleobase found in DNA and RNA. It is an essential component of the human body and is used in the production of phosphoramidites, which are chemical compounds that can be converted into phosphodiester bonds. Adenine has been shown to have anticancer properties, and it may function as a novel activator for other anticancer drugs. Adenine is also used as a monophosphate in some cases. The purity of this compound exceeds 99% and the molecular weight ranges from 162 to 166.5 Daltons.
Formula:C5H5N5Purity:Min. 98.0 Area-%Molecular weight:135.13 g/molN4,3'-O-Dibenzoyl-2'-deoxycytidine
CAS:N4,3'-O-Dibenzoyl-2'-deoxycytidine is a nucleoside that functions as a base. It is a diester of the naturally occurring nucleoside cytidine and 2′,6′-dibenzoyl-deoxyribose. The compound has been shown to be an inhibitor of DNA polymerases and nuclease activity in vitro. N4,3'-O-Dibenzoyl-2'-deoxycytidine has been shown to inhibit the growth of certain strains of bacteria and can be used for the treatment of tuberculosis. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. !-- END OF PRODUCT DESCRIPTIONS -->Formula:C23H21N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:435.44 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine
CAS:2'-Deoxy-5'-O-DMT-5-iodouridine is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.Formula:C30H29IN2O7Purity:Min. 95%Color and Shape:PowderMolecular weight:656.48 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite
N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It is an analog of adenosine and inhibits the action of ribonucleotide reductase, which is an enzyme that converts ribonucleotides to deoxyribonucleotides. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite also inhibits the synthesis of DNA, which may be due to its inhibition of DNA polymerase. This compound has been shown to inhibit the growth of leukemia cells in culture and induce apoptosis in human tumor cells.
Formula:C47H51FN7O7PPurity:Min. 95%Molecular weight:875.92 g/mol6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.Formula:C10H12N4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:268.29 g/mol4-Hydroxy-6-methylpyrimidine
CAS:4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.
Formula:C5H6N2OPurity:Min. 95%Molecular weight:110.11 g/mol1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt
1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is an Activator for the synthesis of DNA and RNA. It is a novel synthetic nucleoside that has anticancer activity. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is used as an antiviral agent, inhibiting viral replication by blocking the RNA polymerase enzyme.Formula:C9H13FN2O14P3·C6H16NPurity:Min. 95%Molecular weight:587.32 g/mol2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt
2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt is a nucleoside that can be used in the synthesis of DNA and RNA. It is a synthetic, high quality, and novel compound that has been shown to have antiviral, anticancer, and anti-inflammatory properties. This compound has been shown to inhibit the growth of cancer cells by inhibiting the production of proteins vital for cell division. 2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt has also been shown to be an activator of nucleoside phosphorylase and deoxynucleotide kinase, which are enzymes that catalyze the conversion of nucleosides into their corresponding monophosphates.Purity:Min. 95%7-Deaza-2'-deoxyadenosine
CAS:7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.Formula:C11H14N4O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:250.26 g/molAdenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS:Adenosine-5'-O-(1-thiotriphosphate) lithium salt is an inhibitor of the guanine nucleotide-binding protein that is reversibly inhibited by adenosine triphosphate. It has been shown to inhibit HIV infection by binding to the Ryanodine receptor and blocking the release of calcium ions from intracellular stores. This prevents the activation of caspases, which are enzymes that cause cell lysis. Adenosine-5'-O-(1-thiotriphosphate) lithium salt also blocks transcription and polymerase chain reactions, and may inhibit the growth of cancer cells by inhibiting epidermal growth factor receptors on the cell surface.Formula:C10H12Li4N5O12P3SPurity:Min. 95%Color and Shape:PowderMolecular weight:546.98 g/molb-Nicotinamide adenine dinucleotide phosphate
CAS:Coenzyme and regenerating electron donor in catabolic processesFormula:C21H28N7O17P3Purity:Min. 80 Area-%Color and Shape:Off-White PowderMolecular weight:743.41 g/mol2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.Formula:C11H19N2O15P3Purity:Min. 95%Molecular weight:512.19 g/mol8-Chloro-2'-deoxyguanosine
CAS:8-Chloro-2'-deoxyguanosine is a reactive oxygen species that can cause oxidative damage to DNA. This compound is generated by the hypochlorous acid (HOCl) in cells and can be found in human tissues. 8-Chloro-2'-deoxyguanosine can also be generated by the HOCl in diabetic patients, where it has been shown to cause oxidative damage to DNA. 8-Chloro-2'-deoxyguanosine is a product of the reaction between hydrogen peroxide and catalase, and it is activated by HOCl. It has been shown to be carcinogenic in animal models, where it causes DNA damage that leads to cancer.Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol5-Amino-2’-deoxy-2’-O-methyluridine HCl
5-Amino-2’-deoxy-2’-O-methyluridine HCl is a novel nucleoside analog that has been modified with an O-methyl group at the 5′ position of the ribose moiety. This modification inhibits phosphorylation by inhibiting DNA polymerase and thus, preventing DNA synthesis. 5-Amino-2’-deoxy-2’-O-methyluridine HCl has also been shown to inhibit viral replication by inhibiting viral RNA and protein synthesis, while not affecting human RNA and protein synthesis. 5AADMUT is an activator of diphosphate metabolism in cells which may be due to its ability to inhibit enzymes involved in nucleotide metabolism (e.g., adenosine kinase).Purity:Min. 95%Ribavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.Formula:C8H15N4O14P3·Na4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:576.1 g/molN6-Carbamoylthreonyladenosine sodium salt
CAS:N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.Formula:C15H19N6O8·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:434.34 g/mol2’-Deoxy-N4-dimethylcytidine
CAS:2’-Deoxy-N4-dimethylcytidine is a synthetic nucleoside analog that is used to inhibit viral replication in the treatment of AIDS and cancer. It is phosphorylated by adenosine kinase to form deoxydimethylcytidine monophosphate (dDMP), which inhibits viral DNA synthesis by inhibiting the activity of reverse transcriptase, an enzyme involved in the production of viral DNA. 2’-Deoxy-N4-dimethylcytidine has also been shown to inhibit cancer cell growth by interrupting mitosis and inducing apoptosis.Purity:Min. 95%3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine
3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that inhibits DNA synthesis by competitively inhibiting the activity of deoxycytidine kinase. 3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is an antiviral agent and has been shown to be effective against herpes simplex virus type 1 and varicella zoster virus. It has also been shown to have anticancer properties, which may be due to its ability to inhibit the growth of human breast cancer cells in culture.Formula:C24H24N4O6Purity:Min. 95%Molecular weight:464.47 g/mol2-Azidoadenosine
CAS:2-Azidoadenosine is a nucleoside analog of adenosine, where the 2'-hydroxyl group of the ribose sugar is replaced with an azido group (–N₃). This substitution imparts unique chemical properties, notably enabling molecules to undergo bioorthogonal reactions, such as click chemistry, which involves the cycloaddition of the azide group with alkynes.
Formula:C10H12H8O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.25 g/mol2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine
2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.Purity:Min. 95%Trifluorothymidine
CAS:Treats herpes-associated keratitis and keratoconjunctivitis; antineoplasticFormula:C10H11F3N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:296.2 g/molUridine 5'-monophosphate
CAS:Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.Formula:C9H13N2O9PPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:324.18 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a novel modified ribonucleoside that has been synthesized to mimic the natural nucleotide. It has been shown to activate DNA synthesis, inhibit cancer cell division and proliferation, and inhibit viral replication. 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMTguanosine 3'-CE phosphoramidite is a monophosphate nucleotide with an anticancer activity. It has also showed antiviral effects against HIV and Hepatitis B virus. This novel modified ribonucleoside is highly pure and can be used for the synthesis of high quality DNA, RNA, or phosphoramidites.Formula:C49H66N7O8PSiPurity:Min. 95%Molecular weight:940.17 g/molb-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)
CAS:b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathioneFormula:C21H30N7O17P3·4C6H13NPurity:Min. 90 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:1,142.12 g/mol5'-O-p-Anisoyl-2,2'-anhydrouridine
5'-O-p-Anisoyl-2,2'-anhydrouridine is a novel nucleoside. It is an activator of ribonucleosides and deoxyribonucleosides. This compound has antiviral activity against HIV and DNA synthesis inhibitory activity against cancer cells. 5'-O-p-Anisoyl-2,2'-anhydrouridine is also a modified nucleoside that can be used for the synthesis of phosphoramidites for the chemical synthesis of oligodeoxynucleotides (ODN).Formula:C17H16N2O7Purity:Min. 95%Molecular weight:360.32 g/mol3-Deaza-2'-O-methyluridine
CAS:3-Deaza-2'-O-methyluridine is a nucleoside that is used as an antiviral agent and in the treatment of leukemia. It has been shown to inhibit the growth of L1210 cells in a dose-dependent manner. 3-Deaza-2'-O-methyluridine also inhibits the synthesis of DNA, RNA, and proteins. The compound is eliminated by renal excretion with a plasma elimination half life of 9 hours. This drug can be administered intramuscularly or intravenously at a dosage of 10 mg/kg every 8 hours, but should not be given more than 5 days without interruption due to accumulation in tissues.
Formula:C11H15NO6Purity:Min. 95%Molecular weight:257.24 g/mol5'-O-DMT-α-thymidine
5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.
Formula:C31H32N2O7Purity:Min. 95%Molecular weight:544.6 g/mol2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine
CAS:2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine is an adenosine analog for potential use in research into antiviral drug development or nucleoside analogs.Formula:C39H33N5O7Purity:Min. 95%Color and Shape:PowderMolecular weight:683.71 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
CAS:2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.Purity:Min. 95%3'-Deoxythymidine
CAS:3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.Formula:C10H14N2O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:226.23 g/mol3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine
CAS:Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt
CAS:N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is a novel modified nucleoside with anticancer activity. The compound is a monophosphate, which activates DNA and RNA synthesis. This agent also has antiviral and antifungal effects. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is synthesized from diphosphate and deoxyribonucleosides. It was first patented in 1979 and has been approved by the US Food and Drug Administration (FDA) for use as a pharmaceutical agent. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt can be used to produce phosphoramidites, which are synthetic DNA building blocks that are used in the production of DNA and RNA synthesis.Formula:C13H16N4O9Na2Purity:Min. 95 Area-%Color and Shape:Off-White PowderMolecular weight:418.27 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS:N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.
Formula:C20H21N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:411.41 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine
CAS:2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine is a modified nucleoside that is used as an anticancer drug. It is synthesized from 2’,3’,5’triphosphate and 2’C-methyl-5-methoxyuridine. This compound is used to treat leukemia and other cancers by inhibiting the synthesis of DNA. Inhibiting DNA synthesis prevents the reproduction of cancer cells. The chemical structure of this compound was first published in 2007.Purity:Min. 95%2'-Deoxyadenosine 3'-O-L-valinyl ester
2'-Deoxyadenosine 3'-O-L-valinyl ester is a novel nucleoside phosphoramidite that is synthesized by activating the 2'-deoxyribose phosphate with an L-valyl chloride. This synthetic nucleoside analog can be used as a substitute for dATP in DNA synthesis and has antiviral as well as anticancer activities.Purity:Min. 95%5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is a modified nucleoside that is synthesized by reacting 5'-O-tert-butyldimethylsilyl guanosine with 2'-deoxyisobutyryl chloride in the presence of triethylamine. The resulting 5'-O-tert-butyldimethylsilyl-2'-deoxyisobutyrylguanosine 3'-CE phosphoramidite has been shown to be cytotoxic to tumor cells without affecting normal cells.Formula:C29H50N7O6PSiPurity:Min. 95%Molecular weight:651.82 g/mol1-(b-L-Threonyl)uracil
1-(b-L-Threonyl)uracil is a novel anticancer drug that has been synthesized with the aim of increasing the efficacy of DNA synthesis. The incorporation of this nucleoside in the DNA chain prevents the formation of ribonuclesides, which are inhibitory to DNA synthesis. It also inhibits viral replication and can be used as a treatment for HIV infection. 1-(b-L-Threonyl)uracil is synthesized by reacting b-L-threonyl chloride with uracil in the presence of a base and a catalytic amount of thiourea. This product is used in biotechnology as an activator for phosphoramidites and modified nucleosides.Purity:Min. 95%3’-Azido-3’-deoxy-b-L-adenosine
CAS:3’-Azido-3’-deoxy-b-L-adenosine is a novel nucleoside that has been synthesized to be used as an antiviral agent. It is phosphorylated, which allows it to be activated by adenosine kinase, and is thus able to inhibit viral replication and spread. 3’-Azido-3’-deoxy-b-L-adenosine is effective against various viruses, including HIV, herpes simplex virus type 1 (HSV1), and hepatitis C virus (HCV). This nucleoside also has anticancer activity due to its ability to inhibit the synthesis of DNA and RNA. It has been modified from the natural nucleosides with the addition of a 2′,3′ azido group at the 3 position on the ribose sugar. The modification prevents viral resistance because it does not require activation by cellular kinases or phosphorylation in order to be active.Purity:Min. 95%3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine
CAS:Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%N6-Benzoyl-2'-C-methyladenosine
N6-Benzoyl-2'-C-methyladenosine is synthetic and has antiviral properties. It is a nucleoside that belongs to the group of modified nucleosides. This compound can be used as an activator for DNA synthesis and as a novel monophosphate, diphosphate, or triphosphate. N6-Benzoyl-2'-C-methyladenosine is also available in high purity, with CAS No., and at a competitive price.Purity:Min. 95%
