G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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MK-2894
CAS:1006036-87-8
MK-2894 is a highly potent and selective antagonist of second generation EP4 .
Formula:
C25H22F3NO3S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
473.51
Ref: TM-T12061
| 1mg | 60.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 216.00 € | ||
| 25mg | 525.00 € | ||
| 50mg | 929.00 € | ||
| 100mg | 1,225.00 € | ||
| 500mg | 2,498.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Friday 16 May 2025
TUG-469
CAS:1236109-67-3
TUG-469 is an agonist of free fatty acid 1(FFA) receptor.
Formula:
C23H23NO2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
345.43
Ref: TM-T34967
| 25mg | 51.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 16 May 2025
SB-215505
CAS:162100-15-4
SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, …
Formula:
C19H16ClN3O
Purity:
98.33%
Color and Shape:
Solid
Molecular weight:
337.8
Ref: TM-T28680
| 1mg | 216.00 € | ||
| 5mg | 540.00 € | ||
| 10mg | 753.00 € | ||
| 25mg | 1,121.00 € | ||
| 50mg | 1,549.00 € |
Estimated delivery in United States, on Friday 16 May 2025
FL104
CAS:885672-81-1
FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.
Formula:
C24H25ClN2O
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
392.92
Ref: TM-T27328
| 1mg | 116.00 € | ||
| 5mg | 273.00 € | ||
| 10mg | 373.00 € | ||
| 25mg | 563.00 € | ||
| 50mg | 758.00 € | ||
| 100mg | 998.00 € | ||
| 200mg | 1,320.00 € | ||
| 1mL*10mM (DMSO) | 333.00 € |
Estimated delivery in United States, on Friday 16 May 2025
LY266097 hydrochloride
CAS:172895-39-5
LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression …
Formula:
C21H24Cl2N2O2
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
407.33
Ref: TM-T22947
| 5mg | 48.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 16 May 2025
SR 2640 hydrochloride
CAS:146662-42-2
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be …
Formula:
C23H19ClN2O3
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
406.86
Ref: TM-T23390
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 273.00 € | ||
| 100mg | 393.00 € | ||
| 200mg | 563.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Compound C108
CAS:15533-09-2
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).
Formula:
C15H14N2O3
Purity:
99.77%
Color and Shape:
Liquid
Molecular weight:
270.28
Ref: TM-T38387
| 1mg | 46.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 130.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 401.00 € | ||
| 100mg | 597.00 € | ||
| 500mg | 1,283.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Friday 16 May 2025
IPAG
CAS:193527-91-2
IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.
Formula:
C17H22IN3
Purity:
98.8%
Color and Shape:
Solid
Molecular weight:
395.28
Ref: TM-T22870
| 1mg | 46.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 655.00 € |
Estimated delivery in United States, on Friday 16 May 2025
IT1t dihydrochloride
CAS:1092776-63-0
IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist …
Formula:
C21H36Cl2N4S2
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
479.57
Ref: TM-T11693L
| 1mg | 42.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 510.00 € | ||
| 100mg | 740.00 € | ||
| 500mg | 1,510.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 16 May 2025
BMY-14802 hydrochloride
CAS:105565-55-7
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 …
Formula:
C18H23ClF2N4O
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
384.85
Ref: TM-T22612
| 5mg | 49.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 353.00 € | ||
| 200mg | 500.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Glemanserin
CAS:107703-78-6
Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM …
Formula:
C20H25NO
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
295.42
Ref: TM-T22964
| 1mg | 40.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 638.00 € | ||
| 500mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 16 May 2025
ORL1 antagonist 1
CAS:1174985-59-1
ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 …
Formula:
C20H22ClN5
Purity:
97.87%
Color and Shape:
Solid
Molecular weight:
367.88
Ref: TM-T12320
| 1mg | 77.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 475.00 € | ||
| 100mg | 638.00 € | ||
| 200mg | 845.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Amosulalol
CAS:85320-68-9
Amosulalol is a combined alpha and beta adrenoceptor antagonist.
Formula:
C18H24N2O5S
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
380.46
Ref: TM-T30027
| 1mg | 185.00 € | ||
| 2mg | 279.00 € | ||
| 5mg | 425.00 € | ||
| 10mg | 625.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,311.00 € | ||
| 100mg | 1,795.00 € | ||
| 1mL*10mM (DMSO) | 454.00 € |
Estimated delivery in United States, on Friday 16 May 2025
OMDM-6
CAS:616884-67-4
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 …
Formula:
C28H42N2O3
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
454.64
Ref: TM-T12307
| 1mg | 115.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 375.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 787.00 € | ||
| 100mg | 1,074.00 € | ||
| 200mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Friday 16 May 2025
VUF 5574
CAS:280570-45-8
VUF 5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 …
Formula:
C21H17N5O2
Purity:
97.63%
Color and Shape:
Solid
Molecular weight:
371.39
Ref: TM-T23518
| 5mg | 62.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 449.00 € |
Estimated delivery in United States, on Friday 16 May 2025
BW 245C
CAS:72814-32-5
BW 245C is a DP1 agonist with an inhibitory effect on the aggregation response of …
Formula:
C19H32N2O5
Purity:
≥99%
Color and Shape:
Solid
Molecular weight:
368.47
Ref: TM-T14842
| 1mg | 190.00 € |
Estimated delivery in United States, on Friday 16 May 2025
ML 10302 hydrochloride
CAS:186826-17-5
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of …
Formula:
C15H22Cl2N2O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
349.25
Ref: TM-T22992
| 2mg | 44.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 333.00 € | ||
| 200mg | 465.00 € |
Estimated delivery in United States, on Friday 16 May 2025
48740 RP
CAS:93363-11-2
48740 RP (RP 55779) is an antagonist of platelet-activating factor.
Formula:
C12H11N3OS
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
245.3
Ref: TM-T10159
| 1mg | 356.00 € | ||
| 5mg | 567.00 € | ||
| 10mg | 907.00 € | ||
| 25mg | 1,339.00 € | ||
| 50mg | 1,815.00 € | ||
| 100mg | 2,432.00 € | ||
| 1mL*10mM (DMSO) | 567.00 € |
Estimated delivery in United States, on Friday 16 May 2025
GRI977143
CAS:325850-81-5
GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.
Formula:
C22H17NO4S
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
391.44
Ref: TM-T22812
| 1mg | 39.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 638.00 € | ||
| 500mg | 1,359.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PPTN hydrochloride
CAS:1992047-65-0
PPTN hydrochloride is a potent, high-affinity, competitive, highly selective P2Y14 receptor antagonist (KB: 434 pM), …
Formula:
C29H25ClF3NO2
Purity:
99.94%
Color and Shape:
Liquid
Molecular weight:
511.96
Ref: TM-T63534
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 687.00 € | ||
| 500mg | 1,444.00 € |
Estimated delivery in United States, on Friday 16 May 2025
