G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Ex26
CAS:1233332-37-0
Ex26 (S1P1-IN-Ex26) is an S1P1 antagonist used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.
Formula:
C28H28ClFN2O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
494.99
Ref: TM-T28643
| 1mg | 109.00 € | ||
| 5mg | 264.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 683.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,267.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Dicarbine
CAS:17411-19-7
Double carbene blocks dopamine receptors, aiding schizophrenia and alcoholism research; it maintains defense reflexes despite …
Formula:
C13H18N2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
202.3
Ref: TM-T13652
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
ESI-08
CAS:301177-43-5
ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively …
Formula:
C20H23N3OS
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
353.48
Ref: TM-T11234
| 1mg | 55.00 € | ||
| 1ml | 164.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 624.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
PNU-282987 free base
CAS:711085-63-1
PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for …
Formula:
C14H17ClN2O
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
264.75
Ref: TM-T60437
| 1mg | 55.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 201.00 € | ||
| 25mg | 392.00 € | ||
| 50mg | 727.00 € | ||
| 100mg | 1,020.00 € | ||
| 500mg | 2,039.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
A2AR-antagonist-1
CAS:2922920-71-4
Oral A2AR-antagonist-1, IC50 29 nM; anti-tumor, stable in mice (t1/2 86.1 min), boosts T cells, …
Formula:
C27H25N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
451.52
Ref: TM-T72626
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
SORT-PGRN interaction inhibitor 3
CAS:2691846-87-2
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as …
Formula:
C15H19Cl2NO3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
332.22
Ref: TM-T79106
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
CAY10786
CAS:1239987-91-7
CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 …
Formula:
C15H14OS
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
242.34
Ref: TM-T36036
| 1ml | 67.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 291.00 € | ||
| 100mg | 458.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
UCM-05194
CAS:2411412-36-5
UCM-05194: potent LPA1 agonist, best for neuropathic pain relief (Emax 118%, EC50 0.24 μM, KD …
Formula:
C19H30BrO6P
Purity:
90% - 98%
Color and Shape:
Solid
Molecular weight:
465.32
Ref: TM-T69647
| 1mg | 315.00 € | ||
| 5mg | 746.00 € | ||
| 10mg | 1,057.00 € | ||
| 25mg | 1,576.00 € | ||
| 50mg | 2,057.00 € | ||
| 100mg | 2,732.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
HSK0935
CAS:1638851-44-1
HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has …
Formula:
C22H25ClO7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
436.88
Ref: TM-T15505
| 25mg | 1,313.00 € | ||
| 50mg | 1,729.00 € | ||
| 100mg | 2,322.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
15-keto-Prostaglandin E2
CAS:26441-05-4
15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast …
Formula:
C20H30O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
350.45
Ref: TM-T78582
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
D4R agonist-1
CAS:2826198-44-9
D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be …
Formula:
C19H22N4S
Purity:
98.16%
Color and Shape:
Solid
Molecular weight:
338.47
Ref: TM-T78825
| 1mg | 326.00 € | ||
| 5mg | 907.00 € | ||
| 10mg | 1,115.00 € | ||
| 25mg | 1,478.00 € | ||
| 50mg | 1,850.00 € | ||
| 100mg | 2,336.00 € | ||
| 500mg | 4,563.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
LP-471756
CAS:413605-11-5
LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 …
Formula:
C19H23NO2S
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
329.46
Ref: TM-T27850
| 1ml | 82.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 554.00 € | ||
| 200mg | 782.00 € | ||
| 500mg | 1,170.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
LY2444296
CAS:1346133-11-6
LY2444296 (FP3FBZ) is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 …
Formula:
C24H22F2N2O2
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
408.44
Ref: TM-T11909
| 5mg | 46.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
PNU-142633
CAS:187665-65-2
PNU-142633: anti-migraine, selective 5-HT1D agonist, Ki=6 nM; >18,000 nM for 5-HT1B.
Formula:
C24H30N4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
422.52
Ref: TM-T16556
| 10mg | 771.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
TUG-469
CAS:1236109-67-3
TUG-469 is an agonist of free fatty acid 1(FFA) receptor.
Formula:
C23H23NO2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
345.43
Ref: TM-T34967
| 10mg | 46.00 € | ||
| 25mg | 80.00 € | ||
| 50mg | 114.00 € | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
Carboprost
CAS:35700-23-3
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect …
Formula:
C21H36O5
Purity:
98.18% - 99.31%
Color and Shape:
White Or Almost White Powder
Molecular weight:
368.51
Ref: TM-T22285
| 1mg | 69.00 € | ||
| 1ml | 205.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 278.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 994.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
EPAC 5376753
CAS:302826-61-5
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in …
Formula:
C15H8Cl2N2O3S
Purity:
90%
Color and Shape:
Solid
Molecular weight:
367.21
Ref: TM-T11212
| 1mg | 52.00 € | ||
| 1ml | 111.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 296.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
FL104
CAS:885672-81-1
FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.
Formula:
C24H25ClN2O
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
392.92
Ref: TM-T27328
| 1mg | 184.00 € | ||
| 1ml | 551.00 € | ||
| 5mg | 446.00 € | ||
| 10mg | 610.00 € | ||
| 25mg | 923.00 € | ||
| 50mg | 1,239.00 € | ||
| 100mg | 1,631.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
LY266097 hydrochloride
CAS:172895-39-5
LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression …
Formula:
C21H24Cl2N2O2
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
407.33
Ref: TM-T22947
| 1ml | 91.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 356.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
SR 2640 hydrochloride
CAS:146662-42-2
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be …
Formula:
C23H19ClN2O3
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
406.86
Ref: TM-T23390
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 447.00 € | ||
| 100mg | 644.00 € | ||
| 500mg | 1,374.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
