G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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SB-277011
CAS:215803-78-4
SB-277011A: dopamine D3 antagonist, pKi 8.0 (D3), 6.0 (D2), 5.0 (5-HT1D), <5.2 (5-HT1B).
Formula:
C28H30N4O
Purity:
98.61%
Color and Shape:
Solid
Molecular weight:
438.56
Ref: TM-T12861
| 1mg | 46.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 154.00 € | ||
| 50mg | 249.00 € | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 14 Jan 2025
GW-493838
CAS:253124-46-8
GW-493838 is a potent adenosine A1A receptor agonist for the treatment of dyslipidemia and neuropathic …
Formula:
C21H21ClFN7O4
Purity:
99.70% - 99.76%
Color and Shape:
Solid
Molecular weight:
489.89
Ref: TM-T27509
| 1mg | 148.00 € | ||
| 5mg | 358.00 € | ||
| 10mg | 508.00 € | ||
| 25mg | 763.00 € | ||
| 50mg | 1,031.00 € | ||
| 100mg | 1,393.00 € | ||
| 500mg | 2,730.00 € | ||
| 1mL*10mM (DMSO) | 419.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Lensiprazine
CAS:327026-93-7
Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake …
Formula:
C24H27FN4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
422.5
Ref: TM-T32633
| 1mg | 179.00 € | ||
| 5mg | 446.00 € | ||
| 10mg | 638.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,375.00 € | ||
| 100mg | 1,859.00 € | ||
| 500mg | 3,641.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Midaglizole hydrochloride
CAS:79689-25-1
Midaglizole hydrochloride (DG5128) is an α2-adrenoceptor antagonist with 7.4x more affinity than α1-adrenoceptors (pKi=6.28).
Formula:
C16H19Cl2N3
Purity:
100% - 98.73%
Color and Shape:
Solid
Molecular weight:
324.25
Ref: TM-T11015
| 1mg | 94.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 325.00 € | ||
| 25mg | 530.00 € | ||
| 50mg | 721.00 € | ||
| 100mg | 919.00 € | ||
| 500mg | 1,843.00 € | ||
| 1mL*10mM (DMSO) | 256.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Dimethindene maleate
CAS:3614-69-5
Dimethindene maleate (SU 6518) is a histamine H1 antagonist and can be used in studies …
Formula:
C24H28N2O4
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
408.49
Ref: TM-T21472
| 1mg | 36.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 246.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 425.00 € | ||
| 500mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Mianserin
CAS:24219-97-4
Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) …
Formula:
C18H20N2
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
264.36
Ref: TM-T21428
| 1mg | 369.00 € | ||
| 5mg | 900.00 € | ||
| 10mg | 1,198.00 € | ||
| 25mg | 1,811.00 € | ||
| 50mg | 2,448.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
NNC 63-0532
CAS:250685-44-0
NNC 63-0532 is a potentnociceptin receptor agonist, Ki=7.3 nM, EC50=305 nM.
Formula:
C27H29N3O3
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
443.54
Ref: TM-T23074
| 1mg | 49.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 277.00 € | ||
| 50mg | 439.00 € | ||
| 100mg | 626.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Darbufelone
CAS:139226-28-1
Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF2α and LTB4.
Formula:
C18H24N2O2S
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
332.46
Ref: TM-T10960
| 1mg | 44.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 551.00 € | ||
| 500mg | 1,098.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Ancarolol
CAS:75748-50-4
Ancarolol is a blocking agent of beta-adrenergic.
Formula:
C18H24N2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
332.39
Ref: TM-T14287
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Edonentan
CAS:210891-04-6
Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study …
Formula:
C28H32N4O5S
Purity:
98.78% - 99%
Color and Shape:
Solid
Molecular weight:
536.64
Ref: TM-T31605
| 1mg | 939.00 € | ||
| 5mg | 1,850.00 € | ||
| 25mg | 2,404.00 € | ||
| 50mg | 2,784.00 € | ||
| 100mg | 3,737.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Roxindole
CAS:112192-04-8
Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.
Formula:
C23H26N2O
Purity:
99.08% - 99.18%
Color and Shape:
Solid
Molecular weight:
346.47
Ref: TM-T26126
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,852.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
RXFP3/4 agonist 2
CAS:2752378-78-0
RXFP3/4 agonist 2 is a nonpeptide bis-RXFP3/4 agonist used in the study of diseases caused …
Formula:
C22H22N6O2
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
402.45
Ref: TM-T61964
| 1mg | 278.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Wy 49051
CAS:113418-56-7
Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).
Formula:
C28H33N5O3
Purity:
97.9%
Color and Shape:
Solid
Molecular weight:
487.59
Ref: TM-T13352
| 1mg | 144.00 € | ||
| 5mg | 273.00 € | ||
| 10mg | 397.00 € | ||
| 25mg | 621.00 € | ||
| 50mg | 835.00 € | ||
| 100mg | 1,080.00 € | ||
| 200mg | 1,446.00 € | ||
| 1mL*10mM (DMSO) | 362.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
MEDICA16
CAS:87272-20-6
MEDICA16: GPR40 agonist, GPR120 partial agonist, ATP-citrate lyase inhibitor, lowers TG, boosts insulin sensitivity in …
Formula:
C20H38O4
Purity:
99.13% - 99.85%
Color and Shape:
White Solid
Molecular weight:
342.51
Ref: TM-T22967
| 5mg | 63.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 434.00 € | ||
| 500mg | 905.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Faxeladol
CAS:433265-65-7
Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.
Formula:
C15H23NO
Purity:
99.11% - 99.13%
Color and Shape:
Solid
Molecular weight:
233.35
Ref: TM-T31750
| 1mg | 597.00 € | ||
| 5mg | 1,258.00 € | ||
| 25mg | 1,692.00 € | ||
| 50mg | 2,023.00 € | ||
| 100mg | 2,610.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
(R)-(-)-α-Methylhistamine dihydrobromide
CAS:868698-49-1
(R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective agonist of H3 histamine receptor( Kd of 50.3 …
Formula:
C6H13Br2N3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
287
Ref: TM-T12630
| 50mg | 1,783.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Thiethylperazine dimaleate
CAS:1179-69-7
Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor.
Formula:
C30H37N3O8S2
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
631.76
Ref: TM-T17072
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 319.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Fipamezole
CAS:150586-58-6
Fipamezole is a potent alpha2 adrenergic receptor antagonist that may be useful for studying autonomic …
Formula:
C14H15FN2
Purity:
100% - 99.32%
Color and Shape:
Solid
Molecular weight:
230.28
Ref: TM-T24064
| 1mg | 597.00 € | ||
| 5mg | 1,253.00 € | ||
| 25mg | 1,692.00 € | ||
| 50mg | 2,025.00 € | ||
| 100mg | 2,601.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
JNJ-39220675
CAS:959740-39-7
JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
Formula:
C21H24FN3O2
Purity:
97.95% - 99.78%
Color and Shape:
Solid
Molecular weight:
369.43
Ref: TM-T27678
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Ronacaleret HCl
CAS:702686-96-2
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and …
Formula:
C25H32ClF2NO4
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
483.98
Ref: TM-T34385
| 1mg | 271.00 € | ||
| 5mg | 666.00 € | ||
| 10mg | 917.00 € | ||
| 25mg | 1,380.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,536.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
