G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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IPAG
CAS:193527-91-2
IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.
Formula:
C17H22IN3
Purity:
98.8%
Color and Shape:
Solid
Molecular weight:
395.28
Ref: TM-T22870
| 1mg | 45.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 449.00 € | ||
| 100mg | 647.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
IT1t dihydrochloride
CAS:1092776-63-0
IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist …
Formula:
C21H36Cl2N4S2
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
479.57
Ref: TM-T11693L
| 1mg | 41.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 279.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 730.00 € | ||
| 500mg | 1,483.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
BMY-14802 hydrochloride
CAS:105565-55-7
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 …
Formula:
C18H23ClF2N4O
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
384.85
Ref: TM-T22612
| 5mg | 49.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 487.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Glemanserin
CAS:107703-78-6
Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM …
Formula:
C20H25NO
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
295.42
Ref: TM-T22964
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 625.00 € | ||
| 500mg | 1,327.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Ipsapirone
CAS:95847-70-4
Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 …
Formula:
C19H23N5O3S
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
401.48
Ref: TM-T22871
| 1mg | 52.00 € | ||
| 2mg | 75.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 387.00 € | ||
| 100mg | 548.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Amosulalol
CAS:85320-68-9
Amosulalol is a combined alpha and beta adrenoceptor antagonist.
Formula:
C18H24N2O5S
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
380.46
Ref: TM-T30027
| 1mg | 182.00 € | ||
| 2mg | 272.00 € | ||
| 5mg | 416.00 € | ||
| 10mg | 615.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,287.00 € | ||
| 100mg | 1,761.00 € | ||
| 1mL*10mM (DMSO) | 452.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
OMDM-6
CAS:616884-67-4
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 …
Formula:
C28H42N2O3
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
454.64
Ref: TM-T12307
| 1mg | 111.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 362.00 € | ||
| 25mg | 542.00 € | ||
| 50mg | 758.00 € | ||
| 100mg | 1,034.00 € | ||
| 200mg | 1,391.00 € | ||
| 1mL*10mM (DMSO) | 272.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Atopaxar
CAS:751475-53-3
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.
Formula:
C29H38FN3O5
Purity:
98.25% - 98.5%
Color and Shape:
Solid
Molecular weight:
527.63
Ref: TM-T1986
| 1mg | 73.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 240.00 € | ||
| 25mg | 435.00 € | ||
| 50mg | 640.00 € | ||
| 100mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
VUF 5574
CAS:280570-45-8
VUF 5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 …
Formula:
C21H17N5O2
Purity:
97.63%
Color and Shape:
Solid
Molecular weight:
371.39
Ref: TM-T23518
| 1g | 1,491.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 148.00 € | ||
| 25mg | 256.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 530.00 € | ||
| 500mg | 1,096.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
BW 245C
CAS:72814-32-5
BW 245C is a DP1 agonist with an inhibitory effect on the aggregation response of …
Formula:
C19H32N2O5
Purity:
≥99%
Color and Shape:
Solid
Molecular weight:
368.47
Ref: TM-T14842
| 1mg | 189.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
ML 10302 hydrochloride
CAS:186826-17-5
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of …
Formula:
C15H22Cl2N2O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
349.25
Ref: TM-T22992
| 2mg | 43.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 76.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 264.00 € | ||
| 100mg | 324.00 € | ||
| 200mg | 453.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
48740 RP
CAS:93363-11-2
48740 RP (RP 55779) is an antagonist of platelet-activating factor.
Formula:
C12H11N3OS
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
245.3
Ref: TM-T10159
| 1mg | 349.00 € | ||
| 5mg | 556.00 € | ||
| 10mg | 888.00 € | ||
| 25mg | 1,312.00 € | ||
| 50mg | 1,778.00 € | ||
| 100mg | 2,382.00 € | ||
| 1mL*10mM (DMSO) | 564.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
GRI977143
CAS:325850-81-5
GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.
Formula:
C22H17NO4S
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
391.44
Ref: TM-T22812
| 1mg | 39.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 625.00 € | ||
| 500mg | 1,333.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
PPTN hydrochloride
CAS:1992047-65-0
PPTN hydrochloride is a potent, high-affinity, competitive, highly selective P2Y14 receptor antagonist (KB: 434 pM), …
Formula:
C29H25ClF3NO2
Purity:
99.94%
Color and Shape:
Liquid
Molecular weight:
511.96
Ref: TM-T63534
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 671.00 € | ||
| 500mg | 1,412.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
LAS38096
CAS:851371-22-7
LAS38096 is an A2B adenosine receptor antagonist (Ki : 17 nM) that is potent, selective …
Formula:
C17H12N6O
Purity:
98.71% - 99.16%
Color and Shape:
Solid
Molecular weight:
316.32
Ref: TM-T27800
| 1mg | 325.00 € | ||
| 5mg | 772.00 € | ||
| 10mg | 1,049.00 € | ||
| 25mg | 1,483.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,321.00 € | ||
| 500mg | 4,568.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
WAY 163909
CAS:428868-32-0
WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).
Formula:
C14H18N2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
214.31
Ref: TM-T17253
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
UNC0006
CAS:1354030-14-0
UNC0006 is a β-arrestin-biased dopamine D2 ligand.
Formula:
C24H29Cl2N3O2
Purity:
98.48% - 99.83%
Color and Shape:
Solid
Molecular weight:
462.41
Ref: TM-T29061
| 1mg | 277.00 € | ||
| 5mg | 682.00 € | ||
| 10mg | 932.00 € | ||
| 25mg | 1,435.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Org41841
CAS:301847-37-0
Org41841 is an agonist of luteinising hormone/chorionic gonadotropin receptor and thyroid stimulating hormone receptor and …
Formula:
C19H22N4O2S2
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
402.53
Ref: TM-T16403
| 1mg | 185.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Clemastine
CAS:15686-51-8
Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.
Formula:
C21H26ClNO
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
343.89
Ref: TM-T19966
| 10mg | 66.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 151.00 € | ||
| 100mg | 220.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Falintolol
CAS:90581-63-8
Falintolol is a novel beta-adrenergic antagonist with antihypertensive effects and can be used to study …
Formula:
C12H24N2O2
Purity:
100% - 100%
Color and Shape:
Liquid
Molecular weight:
228.33
Ref: TM-T68402
| 1mg | 277.00 € | ||
| 5mg | 682.00 € | ||
| 10mg | 932.00 € | ||
| 25mg | 1,351.00 € | ||
| 50mg | 1,823.00 € | ||
| 100mg | 2,462.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
