G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
Read more
KP136
CAS:76239-32-2
KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 …
Formula:
C16H18N4O3
Purity:
98.16% - 99.86%
Color and Shape:
Solid
Molecular weight:
314.34
Ref: TM-T15666
| 1mg | 275.00 € | ||
| 5mg | 676.00 € | ||
| 10mg | 924.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,847.00 € | ||
| 100mg | 2,331.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
BP14979
CAS:1000036-77-0
BP14979 is D3R-selective partial agonist.
Formula:
C23H34N4O2
Purity:
97.36% - 99.23%
Color and Shape:
Solid
Molecular weight:
398.54
Ref: TM-T26890
| 1mg | 275.00 € | ||
| 5mg | 676.00 € | ||
| 10mg | 924.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
AS-35
CAS:108427-72-1
AS-35, an oral selective leukotriene antagonist, counters ileum contractions with IC50: 8 nM (LTC4), 4 …
Formula:
C21H20N6O4
Purity:
98.68%
Color and Shape:
Solid
Molecular weight:
420.42
Ref: TM-T14326
| 1mg | 273.00 € | ||
| 2mg | 406.00 € | ||
| 5mg | 672.00 € | ||
| 10mg | 919.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Pridefine
CAS:5370-41-2
Pridefine: antidepressant, balances serotonin, dopamine, norepinephrine reuptake, weakly releases them.
Formula:
C19H21N
Purity:
99.05% - 99.23%
Color and Shape:
Solid
Molecular weight:
263.38
Ref: TM-T24661
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
CV-6209
CAS:100488-87-7
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor.
Formula:
C34H60ClN3O6
Purity:
100% - 100%
Color and Shape:
Solid
Molecular weight:
642.31
Ref: TM-T27102
| 1mg | 125.00 € | ||
| 5mg | 529.00 € | ||
| 10mg | 830.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Immethridine dihydrobromide
CAS:699020-93-4
Immethridine dihydrobromide is a histamine H3 receptor agonist.
Formula:
C9H11Br2N3
Purity:
97.49% - 98.16%
Color and Shape:
Solid
Molecular weight:
321.01
Ref: TM-T22864
| 1mg | 63.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 549.00 € | ||
| 50mg | 915.00 € | ||
| 100mg | 1,258.00 € | ||
| 500mg | 2,497.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
SK609 HCl
CAS:1092797-77-7
SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.
Formula:
C10H15Cl2N
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
220.14
Ref: TM-T24797
| 1mg | 87.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 459.00 € | ||
| 50mg | 641.00 € | ||
| 100mg | 907.00 € | ||
| 500mg | 1,800.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
JNJ-39220675
CAS:959740-39-7
JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
Formula:
C21H24FN3O2
Purity:
97.95% - 99.78%
Color and Shape:
Solid
Molecular weight:
369.43
Ref: TM-T27678
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Roxindole
CAS:112192-04-8
Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.
Formula:
C23H26N2O
Purity:
99.08% - 99.18%
Color and Shape:
Solid
Molecular weight:
346.47
Ref: TM-T26126
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,852.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Quinupramine
CAS:31721-17-2
Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.
Formula:
C21H24N2
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
304.43
Ref: TM-T60707
| 1mg | 431.00 € | ||
| 5mg | 998.00 € | ||
| 25mg | 1,985.00 € | ||
| 50mg | 2,591.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
E-3620
CAS:151213-86-4
E-3620 is a potent antagonist of the 5-HT3 receptor and can be used to study …
Formula:
C20H27Cl2N3O2
Purity:
98.88% - 98.88%
Color and Shape:
Solid
Molecular weight:
412.35
Ref: TM-T62107
| 1mg | 183.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Friday 22 Nov 2024
Parogrelil Free Base
CAS:139145-27-0
Parogrelil Free Base is a phosphodiesterase inhibitor, improves claudication-limited exercise performance in patients with peripheral …
Formula:
C19H18BrClN4O2
Purity:
98.48% - 99%
Color and Shape:
Solid
Molecular weight:
449.73
Ref: TM-T70793
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Pitolisant
CAS:362665-56-3
Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human …
Formula:
C17H26ClNO
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
295.85
Ref: TM-T60636
| 1ml | 52.00 € | ||
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 306.00 € | ||
| 500mg | 734.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
ADR-851 free base
CAS:138559-56-5
ADR-851 free base is an antagonist of the HT3 receptor.
Formula:
C14H18ClN3O2
Purity:
97.88% - 98.32%
Color and Shape:
Solid
Molecular weight:
295.77
Ref: TM-T23642
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Nemazoline Free Base
CAS:130759-56-7
Nemazoline Free Base: a long-lasting nasal decongestant, better than oxymetazoline, with no systemic effects or …
Formula:
C10H11Cl2N3
Purity:
99.03% - 99.18%
Color and Shape:
Solid
Molecular weight:
244.12
Ref: TM-T71012
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Pipoxazole
CAS:91595-86-7
Pipoxazole, an adrenergic receptor antagonist, is used potentially for the treatment of depression.
Formula:
C14H20N4O
Purity:
97.88% - 99.19%
Color and Shape:
Solid
Molecular weight:
260.33
Ref: TM-T28419
| 1mg | 274.00 € | ||
| 5mg | 670.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,389.00 € | ||
| 50mg | 1,846.00 € | ||
| 100mg | 2,563.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
OPC-14523 hydrochloride
CAS:145969-31-9
OPC-14523 hydrochloride, an oral sigma/5-HT1A agonist, shows potent antidepressant activity with strong receptor affinity.
Formula:
C23H29Cl2N3O2
Purity:
99.70%
Color and Shape:
Solid
Molecular weight:
450.4
Ref: TM-T62711
| 1ml | 942.00 € | ||
| 5mg | 889.00 € | ||
| 10mg | 1,181.00 € | ||
| 25mg | 1,483.00 € | ||
| 50mg | 1,814.00 € | ||
| 100mg | 2,290.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
(R)-ZINC-3573
CAS:2089389-15-9
ZINC-3573: Potent, selective MRGPRX2 activator; triggers mast cell degranulation and calcium release.
Formula:
C18H21N5
Purity:
100%
Color and Shape:
Solid
Molecular weight:
307.39
Ref: TM-T29221
| 1ml | 77.00 € | ||
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 462.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
ADRA1D receptor antagonist 1 HCl
CAS:1191908-14-1
ADRA1D receptor antagonist 1 HCl is a selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) …
Formula:
C15H14Cl2N4O
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
337.2
Ref: TM-T10250
| 1mg | 185.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
AVN-322
CAS:1194574-68-9
AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive …
Formula:
C17H20ClN5O2S
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
393.89
Ref: TM-T26691
| 1mg | 276.00 € | ||
| 5mg | 679.00 € | ||
| 10mg | 928.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
