G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Befetupitant
CAS:290296-68-3
Befupupitant(Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of …
Formula:
C29H29F6N3O2
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
565.55
Ref: TM-T14524
| 1mg | 465.00 € | ||
| 5mg | 1,017.00 € | ||
| 10mg | 1,235.00 € | ||
| 25mg | 1,629.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Rilapine
CAS:79781-95-6
Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can …
Formula:
C22H20ClN3
Purity:
99% - 99.66%
Color and Shape:
Solid
Molecular weight:
361.87
Ref: TM-T26085
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Aminaftone
CAS:14748-94-8
Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to …
Formula:
C18H15NO4
Purity:
96.31% - 99.39%
Color and Shape:
Solid
Molecular weight:
309.32
Ref: TM-T14219
| 1mg | 333.00 € | ||
| 5mg | 922.00 € | ||
| 10mg | 1,140.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
SSR126768A
CAS:785048-28-4
SSR126768A is an oxytocin receptor antagonist that inhibits uterine contractions and may be used to …
Formula:
C33H31Cl2N3O4
Purity:
98.40%
Color and Shape:
Solid
Molecular weight:
604.52
Ref: TM-T28855
| 1mg | 333.00 € | ||
| 5mg | 922.00 € | ||
| 10mg | 1,140.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 500mg | 6,613.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Abt-288
CAS:948845-91-8
ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate …
Formula:
C23H24N4O
Purity:
98% - 98.84%
Color and Shape:
Solid
Molecular weight:
372.46
Ref: TM-T26526
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Friday 16 May 2025
RG-12915
CAS:136174-04-4
RG-12915 is a selective antagonist of 5-HT3(IC50 value of 0.16 nM).
Formula:
C20H25ClN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
360.88
Ref: TM-T12716
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Nelonicline
CAS:1026134-63-3
Nelonicline is a selective agonist of neuronal nicotinic receptors.
Formula:
C17H19N3OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
313.42
Ref: TM-T16281
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
CID-4785700
CAS:852935-07-0
CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase …
Formula:
C22H23ClFN3O3
Purity:
98.19%
Color and Shape:
Liquid
Molecular weight:
431.89
Ref: TM-T71740
| 1mg | 333.00 € | ||
| 5mg | 922.00 € | ||
| 10mg | 1,140.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 500mg | 4,664.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PSB-CB5
CAS:1627710-30-8
PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study …
Formula:
C20H17ClN2O2S
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
384.88
Ref: TM-T27019
| 1mg | 88.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 309.00 € | ||
| 25mg | 518.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Tedatioxetine
CAS:508233-95-2
Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.
Formula:
C18H21NS
Purity:
100% - 98.58%
Color and Shape:
Solid
Molecular weight:
283.43
Ref: TM-T34795
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
AP521
CAS:151227-08-6
AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).
Formula:
C20H19ClN2O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
402.89
Ref: TM-T10344
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Pavinetant
CAS:941690-55-7
Pavinetant (MLE-4901) is an orally available neurokinin-3 receptor (NK3R) antagonist used to improve menopausal symptoms.
Formula:
C26H25N3O3S
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
459.56
Ref: TM-T16114
| 1mg | 81.00 € | ||
| 2mg | 104.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 344.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 622.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Friday 16 May 2025
EMD 56551
CAS:133109-86-1
EMD 56551 is a selective small molecule 5-HT1A receptor agonist with anxiolytic activity for the …
Formula:
C24H31N3O2
Purity:
95.07% - 99.39%
Color and Shape:
Liquid
Molecular weight:
393.522
Ref: TM-T61816
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € |
Estimated delivery in United States, on Friday 16 May 2025
CP 316311
CAS:175139-41-0
CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be …
Formula:
C21H29NO2
Purity:
99.47% - 99.60%
Color and Shape:
Solid
Molecular weight:
327.46
Ref: TM-T15008
| 1mg | 279.00 € | ||
| 5mg | 507.00 € | ||
| 10mg | 648.00 € | ||
| 25mg | 882.00 € | ||
| 50mg | 1,198.00 € | ||
| 100mg | 1,596.00 € |
Estimated delivery in United States, on Friday 16 May 2025
CCX777
CAS:1226686-36-7
CCX777 is a partial agonist recruited to ACKR3 by β-arrestin-2 and is used in cancer …
Formula:
C31H43N7O3S
Purity:
98.73%
Color and Shape:
Solid
Molecular weight:
593.78
Ref: TM-T23866
| 1mg | 284.00 € |
Estimated delivery in United States, on Friday 16 May 2025
N6-(2-Phenylethyl)adenosine
CAS:20125-39-7
N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values …
Formula:
C18H21N5O4
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
371.39
Ref: TM-T12163
| 10mg | 34.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 187.00 € | ||
| 200mg | 334.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Rp-cAMPS sodium
CAS:142439-94-9
Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that …
Formula:
C10H11N5NaO5PS
Purity:
99.71%
Color and Shape:
Liquid
Molecular weight:
367.25
Ref: TM-T36679
| 1mg | 284.00 € |
Estimated delivery in United States, on Friday 16 May 2025
WAY208466 dihydrochloride
CAS:1207064-61-6
WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.
Formula:
C17H20Cl2FN3O2S
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
420.33
Ref: TM-T23527
| 1mg | 65.00 € |
Estimated delivery in United States, on Friday 16 May 2025
AM6545
CAS:1245626-05-4
AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.
Formula:
C26H23Cl2N5O3S
Purity:
97.03%
Color and Shape:
Solid
Molecular weight:
556.46
Ref: TM-T22563
| 1mg | 87.00 € | ||
| 5mg | 205.00 € | ||
| 10mg | 303.00 € | ||
| 25mg | 685.00 € | ||
| 50mg | 937.00 € |
Estimated delivery in United States, on Friday 16 May 2025
GSK1521498
CAS:1426543-84-1
GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR).
Formula:
C24H23F2N4O4P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
500.43
Ref: TM-T11479
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
