G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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CB-25
CAS:869376-63-6
CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in …
Formula:
C25H41NO3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
403.6
Ref: TM-T78083
| 2mg | 94.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
4-Chloro-L-phenylalanine
CAS:14173-39-8
4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases …
Formula:
C9H10ClNO2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
199.63
Ref: TM-T78228
| 5g | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-HT2 agonist-1
CAS:2708279-78-9
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values …
Formula:
C19H23ClN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
346.85
Ref: TM-T79804
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tradipitant
CAS:622370-35-8
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
Formula:
C28H16ClF6N5O
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
587.9
Ref: TM-T17156
| 1mg | 59.00 € | ||
| 1ml | 156.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 323.00 € | ||
| 50mg | 479.00 € | ||
| 100mg | 684.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ST-1006
CAS:1196994-11-2
ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.
Formula:
C16H20Cl2N6
Purity:
98.31% - 99.56%
Color and Shape:
Solid
Molecular weight:
367.28
Ref: TM-T34709
| 1mg | 186.00 € | ||
| 1ml | 531.00 € | ||
| 2mg | 277.00 € | ||
| 5mg | 468.00 € | ||
| 10mg | 750.00 € | ||
| 25mg | 1,217.00 € | ||
| 50mg | 1,500.00 € | ||
| 100mg | 1,867.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
JNJ-37822681 dihydrochloride
CAS:2108806-02-4
JNJ-37822681 dihydrochloride: a selective, fast-dissociating dopamine D₂ antagonist with moderate D2L affinity (Ki 158 nM).
Formula:
C17H19Cl2F5N4
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
445.26
Ref: TM-T11722
| 1mg | 39.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 154.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Crisdesalazine
CAS:927685-43-6
Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1).
Formula:
C16H14F3NO3
Purity:
95.95%
Color and Shape:
Solid
Molecular weight:
325.28
Ref: TM-T27084
| 1mg | 136.00 € | ||
| 2mg | 187.00 € | ||
| 5mg | 328.00 € | ||
| 10mg | 508.00 € | ||
| 25mg | 807.00 € | ||
| 50mg | 1,085.00 € | ||
| 100mg | 1,462.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CXCR2-IN-1
CAS:1873376-49-8
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous …
Formula:
C19H20Cl2FN3O4S
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
476.35
Ref: TM-T10905
| 1mg | 79.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 743.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CCG-63802
CAS:620112-78-9
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.
Formula:
C26H18N4O2S
Purity:
90%
Color and Shape:
Solid
Molecular weight:
450.51
Ref: TM-T14897
| 2mg | 42.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 176.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Brilaroxazine
CAS:1239729-06-6
Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.
Formula:
C22H25Cl2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
450.36
Ref: TM-T14782
| 1mg | 68.00 € | ||
| 1ml | 213.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 236.00 € | ||
| 25mg | 405.00 € | ||
| 50mg | 582.00 € | ||
| 100mg | 796.00 € | ||
| 200mg | 1,062.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NMI 8739
CAS:129024-87-9
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.
Formula:
C30H41NO3
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
463.65
Ref: TM-T11079
| 1mg | 40.00 € | ||
| 1ml | 92.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 296.00 € | ||
| 100mg | 438.00 € | ||
| 500mg | 993.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
2-Methyl-5-HT
CAS:78263-90-8
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
Formula:
C11H14N2O
Purity:
95.64%
Color and Shape:
Solid
Molecular weight:
190.24
Ref: TM-T10075
| 1ml | 53.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 516.00 € | ||
| 500mg | 1,133.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dothiepin
CAS:113-53-1
Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing
Formula:
C19H21NS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
295.44
Ref: TM-T78126
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-HT2 agonist-1 free base
CAS:2708279-77-8
Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C …
Formula:
C19H22N2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
310.39
Ref: TM-T79805
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(Rac)-Modipafant
CAS:122956-68-7
(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.
Formula:
C34H29ClN6O3
Purity:
97.82% - 98.09%
Color and Shape:
Solid
Molecular weight:
605.09
Ref: TM-T28081
| 1mg | 205.00 € | ||
| 5mg | 511.00 € | ||
| 10mg | 739.00 € | ||
| 25mg | 1,138.00 € | ||
| 50mg | 2,250.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Vatinoxan hydrochloride
CAS:130466-38-5
Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.
Formula:
C20H27ClN4O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
454.97
Ref: TM-T13285
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RS 100329 hydrochloride
CAS:1215654-26-4
RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.
Formula:
C20H26ClF3N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
462.89
Ref: TM-T23253
| 1mg | 36.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 461.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A2B receptor antagonist 1
CAS:531506-36-2
A2B receptor antagonist 1 (EXAMPLE 9B) is a potent A2B adenosine receptor antagonist.
Formula:
C21H24N6O2
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
392.45
Ref: TM-T10058
| 1mg | 361.00 € | ||
| 1ml | 838.00 € | ||
| 5mg | 719.00 € | ||
| 10mg | 917.00 € | ||
| 25mg | 1,439.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PZ-1190
CAS:1852517-78-2
PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents …
Formula:
C27H30N4O2S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
506.68
Ref: TM-T81336
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-HT2C agonist-3
CAS:2104810-18-4
5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits …
Formula:
C19H23ClFNO2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
351.84
Ref: TM-T79802
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
