G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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SM-2470
CAS:99899-45-3
SM-2470 is an α1-adrenoceptor antagonist with antihypertensive activity and hypocholesterolemic activity that inhibits cholesterol absorption.
Formula:
C23H30ClN5O3
Purity:
99.05%
Color and Shape:
Liquid
Molecular weight:
459.97
Ref: TM-T62893
| 1mg | 439.00 € | ||
| 5mg | 1,017.00 € | ||
| 25mg | 2,023.00 € | ||
| 50mg | 2,642.00 € | ||
| 100mg | 3,345.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AP521
CAS:151227-08-6
AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).
Formula:
C20H19ClN2O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
402.89
Ref: TM-T10344
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BMY-25271
CAS:78441-82-4
BMY-25271 is an antagonist of histamine H2 receptor.
Formula:
C12H19N5O2S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
329.44
Ref: TM-T10575
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
L-161982
CAS:147776-06-5
L-161982 is a selective EP4 receptor antagonist that inhibits PGE2-induced ERK phosphorylation and cell proliferation …
Formula:
C32H29F3N4O4S2
Purity:
99.44% - 99.91%
Color and Shape:
Solid
Molecular weight:
654.72
Ref: TM-T15681
| 1mg | 79.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
RXFP3/4 agonist 2
CAS:2752378-78-0
RXFP3/4 agonist 2 is a nonpeptide bis-RXFP3/4 agonist used in the study of diseases caused …
Formula:
C22H22N6O2
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
402.45
Ref: TM-T61964
| 1mg | 284.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
EMD 56551
CAS:133109-86-1
EMD 56551 is a selective small molecule 5-HT1A receptor agonist with anxiolytic activity for the …
Formula:
C24H31N3O2
Purity:
95.07% - 99.39%
Color and Shape:
Liquid
Molecular weight:
393.522
Ref: TM-T61816
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
CP-809101
CAS:479683-64-2
CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
Formula:
C15H17ClN4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
304.77
Ref: TM-TQ0130
| 5mg | 221.00 € | ||
| 10mg | 346.00 € | ||
| 25mg | 815.00 € | ||
| 50mg | 1,510.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AS19
CAS:1000578-26-6
AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM).
Formula:
C18H25N3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
283.41
Ref: TM-T10380
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
N6-(2-Phenylethyl)adenosine
CAS:20125-39-7
N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values …
Formula:
C18H21N5O4
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
371.39
Ref: TM-T12163
| 10mg | 34.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 187.00 € | ||
| 200mg | 334.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AZD1940
CAS:881413-29-2
AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. …
Formula:
C20H29F2N3O2S
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
413.52
Ref: TM-T30252
| 1mg | 130.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 535.00 € | ||
| 25mg | 847.00 € | ||
| 50mg | 1,169.00 € | ||
| 100mg | 1,586.00 € | ||
| 1mL*10mM (DMSO) | 344.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Pimethixene maleate
CAS:13187-06-9
Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be …
Formula:
C23H23NO4S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
409.5
Ref: TM-T12489L
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Rp-cAMPS sodium
CAS:142439-94-9
Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that …
Formula:
C10H11N5NaO5PS
Purity:
99.71%
Color and Shape:
Liquid
Molecular weight:
367.25
Ref: TM-T36679
| 1mg | 284.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
WAY208466 dihydrochloride
CAS:1207064-61-6
WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.
Formula:
C17H20Cl2FN3O2S
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
420.33
Ref: TM-T23527
| 1mg | 65.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Bemesetron
CAS:40796-97-2
Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective …
Formula:
C15H17Cl2NO2
Purity:
97.37%
Color and Shape:
Solid
Molecular weight:
314.21
Ref: TM-T14526
| 10mg | 55.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 94.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
RS 42358-197
CAS:135729-55-4
RS 42358-197 (RS 25259-007) is a competitive 5-HT3 receptor antagonist.
Formula:
C19H23ClN2O
Purity:
98.23%
Color and Shape:
Solid
Molecular weight:
330.85
Ref: TM-T20739
| 1mg | 166.00 € | ||
| 5mg | 371.00 € | ||
| 10mg | 557.00 € | ||
| 25mg | 827.00 € | ||
| 50mg | 1,111.00 € | ||
| 100mg | 1,491.00 € | ||
| 200mg | 2,015.00 € | ||
| 1mL*10mM (DMSO) | 369.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SUN 1334H
CAS:607736-84-5
SUN 1334H is a potent, orally active, highly selective antagonist of H1 receptor(Ki of 9.7 …
Formula:
C23H28Cl2F2N2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
489.38
Ref: TM-T13040
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AM6545
CAS:1245626-05-4
AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.
Formula:
C26H23Cl2N5O3S
Purity:
97.03%
Color and Shape:
Solid
Molecular weight:
556.46
Ref: TM-T22563
| 1mg | 87.00 € | ||
| 5mg | 205.00 € | ||
| 10mg | 303.00 € | ||
| 25mg | 685.00 € | ||
| 50mg | 937.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
ICI 162,846
CAS:84545-30-2
ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion …
Formula:
C11H17F3N6O
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
306.29
Ref: TM-T22848
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 208.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
mPGES-1 Inhibitor-1
CAS:1381846-21-4
mPGES-1 Inhibitor-1 is an mPGES-1 inhibitor with anti-inflammatory and analgesic activity, which can be used …
Formula:
C16H19ClN4O2
Purity:
97.90% - 98.98%
Color and Shape:
Solid
Molecular weight:
334.8
Ref: TM-T28089
| 1mg | 187.00 € | ||
| 5mg | 418.00 € | ||
| 10mg | 683.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
GSK1521498
CAS:1426543-84-1
GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR).
Formula:
C24H23F2N4O4P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
500.43
Ref: TM-T11479
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
