G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Dothiepin
CAS:113-53-1
Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing
Formula:
C19H21NS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
295.44
Ref: TM-T78126
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
5-HT2 agonist-1 free base
CAS:2708279-77-8
Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C …
Formula:
C19H22N2O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
310.39
Ref: TM-T79805
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
Selvigaltin
CAS:1978336-95-6
Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the …
Formula:
C19H16BrF3N4O4S
Purity:
99.97%
Color and Shape:
Liquid
Molecular weight:
533.32
Ref: TM-T63751
| 1mg | 269.00 € | ||
| 5mg | 642.00 € | ||
| 10mg | 1,097.00 € | ||
| 25mg | 2,314.00 € | ||
| 50mg | 3,671.00 € | ||
| 100mg | 5,538.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
JNJ-37822681 dihydrochloride
CAS:2108806-02-4
JNJ-37822681 dihydrochloride: a selective, fast-dissociating dopamine D₂ antagonist with moderate D2L affinity (Ki 158 nM).
Formula:
C17H19Cl2F5N4
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
445.26
Ref: TM-T11722
| 5mg | 37.00 € | ||
| 10mg | 52.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
XL413 hydrochloride
CAS:2062200-97-7
XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 …
Formula:
C14H13Cl2N3O2
Purity:
98.81% - 99.82%
Color and Shape:
Solid
Molecular weight:
326.18
Ref: TM-T6735
| 1mg | 52.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 694.00 € | ||
| 200mg | 917.00 € | ||
| 500mg | 1,417.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
(±)-N-Methylcoclaurine
CAS:1472-62-4
N-Methylcoclaurine (±) acts as a selective antagonist at the α2-adrenoceptor [1].
Formula:
C18H21NO3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
299.36
Ref: TM-T79641
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
BLT2 antagonist-1
CAS:2069220-61-5
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis …
Formula:
C26H26FNO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
435.49
Ref: TM-T79418
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Didesmethyl cariprazine
CAS:839712-25-3
Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.
Formula:
C19H28Cl2N4O
Purity:
99.70%
Color and Shape:
Solid
Molecular weight:
399.36
Ref: TM-T15117
| 1mg | 143.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 513.00 € | ||
| 25mg | 806.00 € | ||
| 50mg | 1,095.00 € | ||
| 100mg | 1,475.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
S1P1 agonist 6 hemicalcium
CAS:2941310-03-6
Compound I (S1P1 agonist 6 hemicalcium) is an S1P1 agonist that diminishes autoimmune activity by …
Formula:
C25H26F3NO3Ca
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
465.51
Ref: TM-T79817
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
RS 100329 hydrochloride
CAS:1215654-26-4
RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.
Formula:
C20H26ClF3N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
462.89
Ref: TM-T23253
| 1mg | 36.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 461.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
Ogremorphin
CAS:352563-21-4
Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is …
Formula:
C21H17N3OS
Purity:
99.65% - 99.65%
Color and Shape:
Liquid
Molecular weight:
359.44
Ref: TM-T79209
| 1mg | 377.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
5-HT2A receptor agonist-3
CAS:1391499-52-7
5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting …
Formula:
C21H26BrNO3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
420.34
Ref: TM-T79155
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
MOR agonist-1
CAS:2305781-14-8
MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and …
Formula:
C22H26ClFN2O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
404.91
Ref: TM-T79060
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
Gepirone
CAS:83928-76-1
Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater …
Formula:
C19H29N5O2
Purity:
99.35% - 99.77%
Color and Shape:
Solid
Molecular weight:
359.47
Ref: TM-T19917
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 201.00 € | ||
| 100mg | 276.00 € | ||
| 500mg | 684.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
LTB4 antagonist 3
CAS:2929239-87-0
Compound 24e, a leukotriene B4 (LTB4) antagonist, exhibits an inhibitory concentration 50 (IC50) of 477 …
Formula:
C29H27NO6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
485.53
Ref: TM-T78678
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
KFM19
CAS:133058-72-7
KFM19 is a potent and selective adenosine receptor (A1-receptor) antagonist (IC50 : 50 nM) for …
Formula:
C16H22N4O3
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
318.37
Ref: TM-T15655
| 1mg | 65.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 514.00 € | ||
| 100mg | 731.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
SB 216641 hydrochloride
CAS:193611-67-5
SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.
Formula:
C28H31ClN4O4
Purity:
98.40%
Color and Shape:
Solid
Molecular weight:
523.02
Ref: TM-T23315
| 1mg | 74.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 235.00 € | ||
| 25mg | 395.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 817.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
LTB4 antagonist 1
CAS:2929239-84-7
LTB4 Antagonist 1, a carboxamide-acid derivative, potently inhibits Leukotriene B4 (LTB4) activity with an IC50 …
Formula:
C26H23NO6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
445.46
Ref: TM-T72625
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
CXCR2-IN-1
CAS:1873376-49-8
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous …
Formula:
C19H20Cl2FN3O4S
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
476.35
Ref: TM-T10905
| 1mg | 79.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 743.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
PZ-1190
CAS:1852517-78-2
PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents …
Formula:
C27H30N4O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
506.68
Ref: TM-T81336
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
