G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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mPGES1-IN-3
CAS:1469976-70-2
mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .
Formula:
C24H16ClF5N4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.85
Ref: TM-T12100
| 25mg | 1,827.00 € | ||
| 50mg | 2,413.00 € | ||
| 100mg | 3,180.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
AR-08
CAS:226081-74-9
AR-08 is a potent α2-adrenergic receptor agonist for the study of ADHD and attention deficit.
Formula:
C12H12N6
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
240.26
Ref: TM-T10052
| 1mg | 650.00 € | ||
| 5mg | 1,671.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
BVFP
CAS:357158-20-4
BVFP exhibits affinity for the PGRN 588-593 peptide through binding with a dissociation constant (Kd) …
Formula:
C13H8BrF3N2O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
345.11
Ref: TM-T79105
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
AM-1638
CAS:1142214-62-7
AM-1638 is a full agonist of GPR40/FFA1 (EC50: 0.16 μM).
Formula:
C33H35FO4
Color and Shape:
Solid
Molecular weight:
514.63
Ref: TM-T14200
| 25mg | 829.00 € | ||
| 50mg | 1,086.00 € | ||
| 100mg | 1,629.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Omidenepag isopropyl
CAS:1187451-19-9
Omidenepag isopropyl (DE-117) is a prostaglandin EP2 receptor agonist used in the study of glaucoma …
Formula:
C26H28N6O4S
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
520.6
Ref: TM-T16388
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 734.00 € | ||
| 100mg | 1,198.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Tedalinab
CAS:916591-01-0
Tedalinab is an effective and selective cannabinoid receptor 2 agonist.
Formula:
C19H21F2N3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
345.39
Ref: TM-T17027
| 25mg | 1,055.00 € | ||
| 50mg | 1,411.00 € | ||
| 100mg | 2,198.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Deriglidole
CAS:122830-14-2
Deriglidole (SL 86-0715), an alpha2 receptor inhibitor, blocks colistin/Idazoxan but not prazosin/α2-adrenergic receptors.
Formula:
C16H21N3
Purity:
98.24% - 99.45%
Color and Shape:
Solid
Molecular weight:
255.36
Ref: TM-T10998
| 1mg | 427.00 € | ||
| 5mg | 991.00 € | ||
| 10mg | 1,327.00 € | ||
| 25mg | 1,950.00 € | ||
| 50mg | 2,396.00 € | ||
| 100mg | 3,158.00 € | ||
| 1mL*10mM (DMSO) | 748.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
(R)-Monlunabant
CAS:2765579-76-6
(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research …
Formula:
C26H22ClF3N6O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
591
Ref: TM-T83533
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
(±)-Prenalterol
CAS:57526-81-5
(±)-Prenalterol (H 80/62) is an agonist of beta-2- and beta-1-adrenergic receptors and is used to …
Formula:
C12H19NO3
Purity:
99.71%
Color and Shape:
Liquid
Molecular weight:
225.28
Ref: TM-T25984
| 1mg | 215.00 € | ||
| 2mg | 323.00 € | ||
| 5mg | 537.00 € | ||
| 10mg | 861.00 € | ||
| 25mg | 1,273.00 € | ||
| 50mg | 1,715.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Anti-inflammatory agent 49
CAS:851471-44-8
Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 …
Formula:
C21H22N8O3S
Purity:
99.62% - 99.74%
Color and Shape:
Liquid
Molecular weight:
466.52
Ref: TM-T83057
| 1mg | 96.00 € | ||
| 5mg | 201.00 € | ||
| 10mg | 328.00 € | ||
| 25mg | 656.00 € | ||
| 50mg | 1,029.00 € | ||
| 100mg | 1,397.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Calindol hydrochloride
CAS:729610-18-8
Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an …
Formula:
C21H21ClN2
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
336.86
Ref: TM-T21758
| 1mg | 52.00 € | ||
| 5mg | 148.00 € | ||
| 10mg | 243.00 € | ||
| 25mg | 511.00 € | ||
| 50mg | 812.00 € | ||
| 100mg | 1,301.00 € | ||
| 200mg | 1,754.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
5-HT2A antagonist 1
CAS:204643-75-4
5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.
Formula:
C26H28N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
428.53
Ref: TM-T10498
| 25mg | 1,406.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
AZD9898
CAS:2042347-69-1
AZD9898 inhibits leukotriene-C4 synthetase (IC50: 0.28 nM), aids asthma research, and reduces GABA binding, liver …
Formula:
C20H19ClF3N3O4
Purity:
98.27%
Color and Shape:
Solid
Molecular weight:
457.83
Ref: TM-T14387
| 1mg | 200.00 € | ||
| 5mg | 500.00 € | ||
| 10mg | 733.00 € | ||
| 25mg | 1,178.00 € | ||
| 50mg | 1,568.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
DPI-3290
CAS:182417-73-8
DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 …
Formula:
C30H34FN3O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
487.61
Ref: TM-T15165
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Sigma-1 receptor antagonist 1
CAS:1639220-19-1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor.
Formula:
C19H23Cl2N3O
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
380.31
Ref: TM-T12910
| 1mg | 62.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 365.00 € | ||
| 50mg | 519.00 € | ||
| 100mg | 703.00 € | ||
| 200mg | 903.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Celiprolol hydrochloride
CAS:57470-78-7
Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.
Formula:
C20H33N3O4·HCl
Color and Shape:
White Crystalline Solid
Molecular weight:
415.96
Ref: TM-T1244
| 2mg | 77.00 € | ||
| 1mL*10mM (DMSO) | 138.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Amauromine
CAS:88360-87-6
Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a …
Formula:
C32H36N4O2
Color and Shape:
Solid
Molecular weight:
508.65
Ref: TM-T36566
| 1mg | 500.00 € | ||
| 250µg | 181.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
PF-02575799
CAS:863491-70-7
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
Formula:
C42H37FN4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
680.77
Ref: TM-T16158
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
2-Methyl-5-HT
CAS:78263-90-8
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
Formula:
C11H14N2O
Purity:
95.64%
Color and Shape:
Solid
Molecular weight:
190.24
Ref: TM-T10075
| 5mg | 51.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
INT-777
CAS:1199796-29-6
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM.
Formula:
C27H46O5
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
450.65
Ref: TM-T11662L
| 1mg | 134.00 € | ||
| 2mg | 185.00 € | ||
| 5mg | 322.00 € | ||
| 10mg | 463.00 € | ||
| 25mg | 781.00 € | ||
| 50mg | 1,078.00 € | ||
| 100mg | 1,449.00 € | ||
| 1mL*10mM (DMSO) | 361.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
