G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Nalmefene
CAS:55096-26-9
Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used in the study …
Formula:
C21H25NO3
Color and Shape:
Liquid
Molecular weight:
339.43
Ref: TM-T86954
| 5mg | 61.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 179.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
PF-4693627
CAS:1312815-93-2
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).
Formula:
C26H29Cl2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
502.43
Ref: TM-T16504
| 1mg | 167.00 € | ||
| 5mg | 757.00 € | ||
| 10mg | 1,413.00 € | ||
| 500µg | 92.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Orvepitant maleate
CAS:579475-24-4
Orvepitant maleate, a selective NK-1 receptor antagonist (pKi 10.2), may treat depression and CRC; crosses …
Formula:
C35H39F7N4O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
744.7
Ref: TM-T16406
| 25mg | 639.00 € | ||
| 50mg | 854.00 € | ||
| 100mg | 1,271.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Vofopitant dihydrochloride
CAS:168266-51-1
Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for …
Formula:
C21H25Cl2F3N6O
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
505.36
Ref: TM-T13329L
| 1mg | 96.00 € | ||
| 5mg | 229.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 695.00 € | ||
| 50mg | 1,039.00 € | ||
| 100mg | 1,419.00 € | ||
| 500mg | 2,753.00 € | ||
| 1mL*10mM (DMSO) | 260.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Dersimelagon
CAS:1835256-48-8
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.
Formula:
C36H45F4N3O5
Purity:
97.35% - 98.23%
Color and Shape:
Solid
Molecular weight:
675.75
Ref: TM-T25310
| 1mg | 78.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 260.00 € | ||
| 25mg | 444.00 € | ||
| 50mg | 638.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
GnRH-R antagonist 1
CAS:2826273-90-7
Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.
Formula:
C31H28F5N7O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
721.65
Ref: TM-T72492
| 25mg | 2,245.00 € | ||
| 50mg | 2,972.00 € | ||
| 100mg | 4,019.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
BAY 38-7271
CAS:212188-60-8
BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM …
Formula:
C20H21F3O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
430.44
Ref: TM-T14504
| 25mg | 2,384.00 € | ||
| 50mg | 3,161.00 € | ||
| 100mg | 4,302.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
(S)-Bucindolol
CAS:91548-61-7
(S)-Bucindolol is an enantiomer of bucindolol, specifically a β1-adrenergic receptor antagonist. It is primarily utilized …
Formula:
C22H25N3O2
Color and Shape:
Liquid
Molecular weight:
363.45
Ref: TM-T200285
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
CS-003 Free base
CAS:191672-52-3
CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats …
Formula:
C34H38Cl2N2O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
673.65
Ref: TM-T10892
| 25mg | 2,384.00 € | ||
| 50mg | 3,159.00 € | ||
| 100mg | 4,299.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
TAAR1 agonist 2
CAS:1804128-38-8
TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), …
Formula:
C9H11NO
Color and Shape:
Liquid
Molecular weight:
149.19
Ref: TM-T200140
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Rodatristat ethyl
CAS:1673571-51-1
Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low …
Formula:
C29H31ClF3N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
590.04
Ref: TM-T16779
| 25mg | 2,233.00 € | ||
| 50mg | 3,615.00 € | ||
| 100mg | 5,781.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Norbinaltorphimine dihydrochloride
CAS:113158-34-2
Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses …
Formula:
C40H45Cl2N3O6
Purity:
99%
Color and Shape:
Solid
Molecular weight:
734.71
Ref: TM-T12241
| 1mg | 40.00 € | ||
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
AM9405
AM9405: peripheral CB1/5-HT3 agonist, suppresses gut motility, relieves GI disorder symptoms in mice.
Formula:
C24H33BrN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
461.44
Ref: TM-T10294
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
BQ-788
CAS:173326-37-9
BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation …
Formula:
C34H51N5O7
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
641.8
Ref: TM-T10595
| 1mg | 134.00 € | ||
| 2mg | 184.00 € | ||
| 5mg | 327.00 € | ||
| 10mg | 467.00 € | ||
| 25mg | 746.00 € | ||
| 50mg | 1,006.00 € | ||
| 100mg | 1,363.00 € | ||
| 500mg | 2,674.00 € | ||
| 1mL*10mM (DMSO) | 358.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Pexacerfont
CAS:459856-18-9
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for …
Formula:
C18H24N6O
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
340.42
Ref: TM-T16475
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Befiradol hydrochloride
CAS:2436760-81-3
Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 …
Formula:
C20H23Cl2F2N3O
Purity:
99.1%
Color and Shape:
Solid
Molecular weight:
430.32
Ref: TM-T62385
| 1mg | 149.00 € | ||
| 2mg | 213.00 € | ||
| 5mg | 357.00 € | ||
| 10mg | 522.00 € | ||
| 25mg | 841.00 € | ||
| 50mg | 1,160.00 € | ||
| 100mg | 1,556.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
(R)-SCH 546738
CAS:2181148-54-7
(R)-SCH 546738, the R-isomer of SCH 546738, is a non-competitive, orally active antagonist targeting the …
Formula:
C23H31Cl2N7O
Color and Shape:
Liquid
Molecular weight:
492.45
Ref: TM-T200169
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Mar 2025
SB 243213 hydrochloride
CAS:200940-23-4
SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi …
Formula:
C22H20ClF3N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
464.87
Ref: TM-T12859
| 25mg | 2,106.00 € | ||
| 50mg | 2,785.00 € | ||
| 100mg | 3,739.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
SB-224289 hydrochloride
CAS:180084-26-8
SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.
Formula:
C32H33ClN4O3
Purity:
97.82% - 98.09%
Color and Shape:
Solid
Molecular weight:
557.08
Ref: TM-T12841
| 5mg | 52.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
Sulamserod
CAS:219757-90-1
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study …
Formula:
C19H28ClN3O5S
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
445.96
Ref: TM-T13021
| 1mg | 650.00 € | ||
| 5mg | 1,671.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
