G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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SAR-114137
CAS:537706-31-3
SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and …
Formula:
C25H34N4O7S
Purity:
100% - 99.57%
Color and Shape:
Solid
Molecular weight:
534.63
Ref: TM-T28658
| 1mg | 444.00 € | ||
| 5mg | 1,023.00 € | ||
| 10mg | 1,386.00 € | ||
| 25mg | 2,117.00 € | ||
| 50mg | 2,779.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
L-371,257
CAS:162042-44-6
L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of …
Formula:
C28H33N3O6
Purity:
100%
Color and Shape:
Solid
Molecular weight:
507.58
Ref: TM-T15682
| 1mg | 40.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 367.00 € | ||
| 100mg | 523.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
GnRH-R antagonist 1
CAS:2826273-90-7
Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.
Formula:
C31H28F5N7O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
721.65
Ref: TM-T72492
| 25mg | 2,245.00 € | ||
| 50mg | 2,972.00 € | ||
| 100mg | 4,019.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
SCH 563705
CAS:473728-58-4
SCH 563705 is a CXCR2 and CXCR1 antagonist used in the study of acute respiratory …
Formula:
C23H27N3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
425.48
Ref: TM-T16864
| 1mg | 309.00 € | ||
| 5mg | 738.00 € | ||
| 10mg | 1,154.00 € | ||
| 25mg | 1,716.00 € | ||
| 50mg | 2,326.00 € | ||
| 1mL*10mM (DMSO) | 828.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
KAG-308
CAS:1215192-68-9
KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, …
Formula:
C24H30F2N4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
460.52
Ref: TM-T15642
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 25 Feb 2025
16,16-Dimethyl prostaglandin E2
CAS:39746-25-3
16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.
Formula:
C22H36O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
380.52
Ref: TM-T10046
| 1mg | 204.00 € | ||
| 5mg | 947.00 € | ||
| 10mg | 1,783.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Norbinaltorphimine dihydrochloride
CAS:113158-34-2
Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses …
Formula:
C40H45Cl2N3O6
Purity:
99%
Color and Shape:
Solid
Molecular weight:
734.71
Ref: TM-T12241
| 1mg | 40.00 € | ||
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Sulamserod
CAS:219757-90-1
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study …
Formula:
C19H28ClN3O5S
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
445.96
Ref: TM-T13021
| 1mg | 650.00 € | ||
| 5mg | 1,671.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Befiradol hydrochloride
CAS:2436760-81-3
Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 …
Formula:
C20H23Cl2F2N3O
Purity:
99.1%
Color and Shape:
Solid
Molecular weight:
430.32
Ref: TM-T62385
| 1mg | 149.00 € | ||
| 2mg | 213.00 € | ||
| 5mg | 357.00 € | ||
| 10mg | 522.00 € | ||
| 25mg | 841.00 € | ||
| 50mg | 1,160.00 € | ||
| 100mg | 1,556.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
BMS-986141
CAS:1478711-48-6
BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an …
Formula:
C27H23N5O5S2
Purity:
98.36% - 99.11%
Color and Shape:
Solid
Molecular weight:
561.63
Ref: TM-T63966
| 1mg | 736.00 € | ||
| 5mg | 1,476.00 € | ||
| 10mg | 1,840.00 € | ||
| 25mg | 2,634.00 € | ||
| 50mg | 3,531.00 € | ||
| 100mg | 4,792.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Vofopitant
CAS:168266-90-8
Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for …
Formula:
C21H23F3N6O
Purity:
97.61%
Color and Shape:
Solid
Molecular weight:
432.44
Ref: TM-T13329
| 1mg | 97.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 342.00 € | ||
| 25mg | 554.00 € | ||
| 50mg | 802.00 € | ||
| 100mg | 1,079.00 € | ||
| 500mg | 2,157.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
VA012
CAS:885898-58-8
VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. …
Formula:
C21H19N3
Color and Shape:
Liquid
Molecular weight:
313.4
Ref: TM-T200241
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 25 Feb 2025
TAAR1 agonist 3
CAS:1804129-70-1
TAAR1 agonist 3 is a potent agonist of Trace Amine-Associated Receptor 1 (TAAR1) with a …
Formula:
C10H13NO
Color and Shape:
Liquid
Molecular weight:
163.22
Ref: TM-T200046
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 25 Feb 2025
AZD5462
CAS:2787501-83-9
AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart …
Formula:
C30H41FN2O6
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
544.65
Ref: TM-T63838
| 1mg | 355.00 € | ||
| 5mg | 836.00 € | ||
| 10mg | 1,207.00 € | ||
| 25mg | 1,882.00 € | ||
| 50mg | 2,642.00 € | ||
| 100mg | 3,268.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
LSN3318839
CAS:2764704-18-7
LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled …
Formula:
C26H23Cl2N3O2
Purity:
99.43%
Color and Shape:
Liquid
Molecular weight:
480.39
Ref: TM-T63166
| 1mg | 199.00 € | ||
| 5mg | 502.00 € | ||
| 10mg | 725.00 € | ||
| 25mg | 1,095.00 € | ||
| 50mg | 1,476.00 € | ||
| 100mg | 2,014.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Tonapofylline
CAS:340021-17-2
Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure …
Formula:
C22H32N4O4
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
416.51
Ref: TM-T17117
| 1mg | 43.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 387.00 € | ||
| 100mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
PF-07258669
CAS:2755890-53-8
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia …
Formula:
C25H27FN6O2
Purity:
99.90%
Color and Shape:
Liquid
Molecular weight:
462.52
Ref: TM-T69526
| 1mg | 789.00 € | ||
| 5mg | 1,578.00 € | ||
| 10mg | 2,567.00 € | ||
| 25mg | 5,068.00 € | ||
| 50mg | 8,110.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
F 14679
CAS:208109-38-0
F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to …
Formula:
C21H25ClF2N4O
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
422.9
Ref: TM-T62269
| 25mg | 1,234.00 € | ||
| 50mg | 1,604.00 € | ||
| 100mg | 2,419.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
SB 243213 hydrochloride
CAS:200940-23-4
SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi …
Formula:
C22H20ClF3N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
464.87
Ref: TM-T12859
| 25mg | 2,106.00 € | ||
| 50mg | 2,785.00 € | ||
| 100mg | 3,739.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
LY2794193
CAS:2173037-97-1
LY2794193 is a highly effective and selective agonist of the mGlu3 receptor (hmGlu3 Ki=0.927 nM,EC50=0.47 …
Formula:
C16H18N2O6
Color and Shape:
Solid
Molecular weight:
334.32
Ref: TM-T15807
| 5mg | 490.00 € | ||
| 25mg | 1,679.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 3,061.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
