G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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TC LPA5 4
CAS:1393814-38-4
TC LPA5 4 is a LPA5 receptor antagonist.
Formula:
C23H23ClN2O3
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
410.89
Ref: TM-T23438
| 1mg | 59.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 432.00 € | ||
| 50mg | 638.00 € | ||
| 100mg | 908.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Burixafor hydrobromide
CAS:1191450-19-7
Burixafor hydrobromide is an oral CXCR4 blocker with anti-angiogenic properties, potentially treating choroid neovascularization.
Formula:
C27H52BrN8O3P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
647.644
Ref: TM-T10635
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Friday 16 May 2025
CRTh2 antagonist 1
CAS:1379445-54-1
CRTh2 antagonist 1 is a CRTh2 antagonist (IC50: 89 nM).
Formula:
C23H25N3O5S
Purity:
97.39%
Color and Shape:
Solid
Molecular weight:
455.53
Ref: TM-T10084
| 1mg | 115.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 374.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 787.00 € | ||
| 100mg | 1,074.00 € | ||
| 500mg | 2,147.00 € | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Friday 16 May 2025
VA-K-14 hydrochloride
CAS:1171341-19-7
VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits …
Formula:
C18H16ClN3S
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
341.86
Ref: TM-T29087
| 1mg | 59.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 938.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Palonosetron
CAS:135729-61-2
Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and …
Formula:
C19H24N2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
296.41
Ref: TM-T22393
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
L748337
CAS:244192-94-7
L748337 is a β3-adrenoceptor antagonist that inhibits β3-, β2-, and β1-adrenoceptors and inhibits the protective …
Formula:
C26H31N3O5S
Purity:
99.67% - 99.67%
Color and Shape:
Solid
Molecular weight:
497.61
Ref: TM-T22905
| 1mg | 69.00 € |
Estimated delivery in United States, on Friday 16 May 2025
rac-NBI-74330
CAS:473722-68-8
rac-NBI-74330 is an effective and selective CXCR3 antagonist.
Formula:
C32H27F4N5O3
Purity:
97.85%
Color and Shape:
Solid
Molecular weight:
605.58
Ref: TM-T26035
| 1mg | 96.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 294.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 723.00 € | ||
| 100mg | 1,017.00 € |
Estimated delivery in United States, on Friday 16 May 2025
SKF83959
CAS:80751-85-5
SKF83959: dopamine D1 partial agonist, Ki: D1(1.18 nM), D5(7.56 nM), D2(920 nM), D3(399 nM); improves …
Formula:
C18H20ClNO2
Purity:
98.45%
Color and Shape:
Liquid
Molecular weight:
317.81
Ref: TM-T60835
| 1mg | 52.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 530.00 € | ||
| 100mg | 758.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PD 168568 dihydrochloride
CAS:1782532-06-2
PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 …
Formula:
C22H29Cl2N3O
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
422.39
Ref: TM-T12383
| 5mg | 48.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 248.00 € | ||
| 200mg | 348.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Friday 16 May 2025
MK-0249
CAS:862309-06-6
MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).
Formula:
C23H24F3N3O2
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
431.45
Ref: TM-T12054
| 1mg | 227.00 € | ||
| 5mg | 562.00 € | ||
| 10mg | 815.00 € | ||
| 25mg | 1,206.00 € | ||
| 50mg | 1,605.00 € | ||
| 100mg | 2,175.00 € | ||
| 200mg | 2,822.00 € |
Estimated delivery in United States, on Friday 16 May 2025
SCH 546738
CAS:906805-42-3
SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development …
Formula:
C23H31Cl2N7O
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
492.45
Ref: TM-T16863
| 2mg | 225.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PF2562
CAS:1609258-91-4
PF2562: Dopamine D1 ligand, agonist/partial agonist. Binds D1 receptor (Ki: 113 nM), active in cAMP …
Formula:
C19H17N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
331.37
Ref: TM-T16511
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
ROS 234 dioxalate
CAS:1781941-93-2
ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)
Formula:
C17H19N5O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
421.37
Ref: TM-T12756
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 16 May 2025
LY 272015 hydrochloride
CAS:172895-15-7
LY 272015 hydrochloride is a 5-HT2B receptor antagonist.
Formula:
C21H25ClN2O2
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
372.89
Ref: TM-T22948
| 1mg | 49.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 677.00 € | ||
| 100mg | 1,074.00 € | ||
| 200mg | 1,444.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Masupirdine mesylate
CAS:1791396-46-7
Masupirdine mesylate (SUVN-502 mesylate) is a 5-HT6 receptor antagonist.Masupirdine mesylate is used to study neurological …
Formula:
C23H32BrN3O9S3
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
670.61
Ref: TM-T11949
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 612.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Friday 16 May 2025
SR144528
CAS:192703-06-3
SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal …
Formula:
C29H34ClN3O
Purity:
99.6%
Color and Shape:
Solid
Molecular weight:
476.05
Ref: TM-T16928
| 1mg | 43.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 507.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Odapipam
CAS:131796-63-9
Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of …
Formula:
C19H20ClNO2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
329.82
Ref: TM-T12288
| 25mg | 1,159.00 € | ||
| 50mg | 1,510.00 € | ||
| 100mg | 2,308.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Sitaxsentan
CAS:184036-34-8
Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.
Formula:
C18H15ClN2O6S2
Purity:
97.99% - 99.34%
Color and Shape:
Solid
Molecular weight:
454.9
Ref: TM-T12924
| 1mg | 89.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 329.00 € | ||
| 25mg | 510.00 € | ||
| 50mg | 690.00 € | ||
| 100mg | 938.00 € | ||
| 500mg | 1,882.00 € |
Estimated delivery in United States, on Friday 16 May 2025
GR 89696 fumarate
CAS:126766-32-3
GR 89696 fumarate is a highly selective κ2 opioid receptor agonist (IC50 = 0.04nM) with …
Formula:
C23H29Cl2N3O7
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
530.4
Ref: TM-T22810
| 5mg | 64.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 334.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Crinecerfont
CAS:752253-39-7
Crinecerfont (SSR-125543) is a CRF1 antagonist, useful in congenital adrenal hyperplasia research.
Formula:
C27H28ClFN2OS
Purity:
98.01% - 99.10%
Color and Shape:
Solid
Molecular weight:
483.04
Ref: TM-T31095
| 1mg | 115.00 € | ||
| 2mg | 172.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 375.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 792.00 € | ||
| 100mg | 1,064.00 € | ||
| 500mg | 2,147.00 € |
Estimated delivery in United States, on Friday 16 May 2025
