G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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L-745870
CAS:158985-00-3
L-745870 is a selective dopamine D4 antagonist, brain-penetrant, with lesser affinity for D2/D3 receptors (Ki: …
Formula:
C18H19ClN4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
326.82
Ref: TM-T11799L
| 2mg | 41.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
ISAM-140
CAS:932191-62-3
ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.
Formula:
C19H19N3O3
Purity:
97.41%
Color and Shape:
Solid
Molecular weight:
337.37
Ref: TM-T27629
| 1mg | 57.00 € | ||
| 1ml | 124.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 277.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 592.00 € | ||
| 500mg | 1,163.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
AM-4668
CAS:1011531-27-3
AM-4668: Type 2 diabetes GPR40 agonist with EC50s of 3.6 nM (IP3 assay) and 36 …
Formula:
C24H19F3N2O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
488.48
Ref: TM-T14202
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
SB-277011 dihydrochloride
CAS:1226917-67-4
SB-277011 dihydrochloride: potent, selective D3 antagonist; orally bioavailable; crosses blood-brain barrier; pKi 8.0 for D3 …
Formula:
C28H32Cl2N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
511.49
Ref: TM-T12861L
| 1mg | 108.00 € | ||
| 5mg | 280.00 € | ||
| 10mg | 459.00 € | ||
| 25mg | 1,006.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Flumexadol
CAS:30914-89-7
Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for …
Formula:
C11H12F3NO
Purity:
98%
Color and Shape:
Solid
Molecular weight:
231.21
Ref: TM-T11302
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
PD 144418
CAS:154130-99-1
PD 144418 displays potential antipsychotic activity.
Formula:
C18H22N2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
282.38
Ref: TM-T16445
| 25mg | 682.00 € | ||
| 50mg | 887.00 € | ||
| 100mg | 1,338.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
H2L5186303
CAS:139262-76-3
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
Formula:
C26H20N2O8
Purity:
97.23%
Color and Shape:
Solid
Molecular weight:
488.45
Ref: TM-T22835
| 1mg | 35.00 € | ||
| 1ml | 76.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 460.00 € | ||
| 500mg | 917.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
5-HT7 agonist 1
CAS:334974-31-1
5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).
Formula:
C19H20ClN3
Purity:
98.61%
Color and Shape:
Solid
Molecular weight:
325.84
Ref: TM-T10170
| 1mg | 113.00 € | ||
| 1ml | 253.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 551.00 € | ||
| 50mg | 771.00 € | ||
| 100mg | 1,052.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
CAY10595
CAS:916047-16-0
CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.
Formula:
C20H13Cl2FN2O5
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
451.23
Ref: TM-T10691
| 1mg | 50.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 324.00 € | ||
| 25mg | 429.00 € | ||
| 50mg | 641.00 € | ||
| 100mg | 864.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
ADRA1D receptor antagonist 1 HCl
CAS:1191908-14-1
ADRA1D receptor antagonist 1 HCl is a selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) …
Formula:
C15H14Cl2N4O
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
337.2
Ref: TM-T10250
| 1mg | 185.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
GSK299115A
CAS:864082-35-9
GSK299115A (GSK-299115A) is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for …
Formula:
C20H16Cl2N4O2
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
415.27
Ref: TM-T27471
| 1mg | 314.00 € | ||
| 1ml | 937.00 € | ||
| 5mg | 755.00 € | ||
| 10mg | 1,054.00 € | ||
| 25mg | 1,560.00 € | ||
| 50mg | 2,107.00 € | ||
| 100mg | 2,759.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
SLF1081851
CAS:2763730-97-6
SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.
Formula:
C21H33N3O
Purity:
98.57%
Color and Shape:
Solid
Molecular weight:
343.51
Ref: TM-T61112
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 392.00 € | ||
| 50mg | 586.00 € | ||
| 100mg | 835.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Sergliflozin etabonate
CAS:408504-26-7
Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about …
Formula:
C23H28O9
Purity:
95.59%
Color and Shape:
Solid
Molecular weight:
448.46
Ref: TM-T28757
| 1mg | 182.00 € | ||
| 1ml | 486.00 € | ||
| 2mg | 272.00 € | ||
| 5mg | 418.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,281.00 € | ||
| 100mg | 1,762.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Alniditan
CAS:152317-89-0
Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 …
Formula:
C17H26N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
302.41
Ref: TM-T14190
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
CRTh2 antagonist 2
CAS:780763-95-3
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 …
Formula:
C26H23ClN4O3
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
474.94
Ref: TM-T10889
| 1mg | 106.00 € | ||
| 1ml | 273.00 € | ||
| 5mg | 202.00 € | ||
| 10mg | 328.00 € | ||
| 25mg | 524.00 € | ||
| 50mg | 716.00 € | ||
| 100mg | 920.00 € | ||
| 500mg | 1,845.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
TAK-875 Hemihydrate
CAS:1374598-80-7
TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more …
Formula:
C29H32O7SH2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
533.63
Ref: TM-T2351L
| 1ml | 304.00 € | ||
| 25mg | 621.00 € | ||
| 50mg | 810.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
MM 77 dihydrochloride
CAS:159187-70-9
MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.
Formula:
C19H29Cl2N3O3
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
418.36
Ref: TM-T23007
| 1mg | 50.00 € | ||
| 1ml | 169.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 542.00 € | ||
| 200mg | 717.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Methiothepin maleate
CAS:19728-88-2
Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
Formula:
C24H28N2O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
472.62
Ref: TM-T4375
| 10mg | 86.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 437.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
DBIBB
CAS:1569309-92-7
DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.
Formula:
C23H20N2O6S
Purity:
97.18% - 97.26%
Color and Shape:
Solid
Molecular weight:
452.48
Ref: TM-T22070
| 1mg | 41.00 € | ||
| 1ml | 92.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 543.00 € | ||
| 500mg | 1,089.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Iodophenpropit dihydrobromide
CAS:145196-87-8
Iodophenpropit dihydrobromide: selective histamine H3 antagonist, reversible binding, high affinity (KD: 0.32 nM).
Formula:
C15H20BrIN4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
495.22
Ref: TM-T15590
| 5mg | 279.00 € | ||
| 10mg | 418.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
