G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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SB 611812
CAS:345892-71-9
SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about …
Formula:
C17H16Cl3F3N2O3S
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
491.74
Ref: TM-T23323
| 1mg | 45.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 434.00 € | ||
| 100mg | 609.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
P2Y2R/GPR17 antagonist 1
CAS:2395016-49-4
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: …
Formula:
C19H13ClN2O6S
Purity:
98.21%
Color and Shape:
Liquid
Molecular weight:
432.83
Ref: TM-T62420
| 5mg | 37.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 161.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Pipoxazole
CAS:91595-86-7
Pipoxazole, an adrenergic receptor antagonist, is used potentially for the treatment of depression.
Formula:
C14H20N4O
Purity:
97.88% - 99.19%
Color and Shape:
Solid
Molecular weight:
260.33
Ref: TM-T28419
| 1mg | 274.00 € | ||
| 5mg | 670.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,389.00 € | ||
| 50mg | 1,846.00 € | ||
| 100mg | 2,563.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
4-PPBP maleate
CAS:201216-39-9
4-PPBP maleate: potent σ1 agonist, selective NR1a/2B NMDA antagonist, neuroprotective.
Formula:
C25H31NO4
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
409.52
Ref: TM-T22513
| 5mg | 73.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,093.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
8-OH-Dpat
CAS:78950-78-4
8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects …
Formula:
C16H25NO
Purity:
98%
Color and Shape:
Solid
Molecular weight:
247.38
Ref: TM-T4305
| 5mg | 46.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 252.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
CGP 35949
CAS:111130-13-3
CGP 35949 is an LTD4 antagonist with phospholipase inhibitory activity.
Formula:
C23H25ClN5NaO5
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
509.92
Ref: TM-T30828
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,049.00 € | ||
| 500mg | 2,108.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
ORM-10921
CAS:610782-82-6
ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.
Formula:
C18H23NO2
Purity:
99.46% - 99.75%
Color and Shape:
Solid
Molecular weight:
285.38
Ref: TM-T28267
| 1mg | 371.00 € | ||
| 5mg | 900.00 € | ||
| 10mg | 1,198.00 € | ||
| 25mg | 1,810.00 € | ||
| 50mg | 2,434.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
U 99194 maleate
CAS:234757-41-6
U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced …
Formula:
C21H31NO6
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
393.47
Ref: TM-T23483
| 1mg | 91.00 € | ||
| 2mg | 121.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 467.00 € | ||
| 50mg | 678.00 € | ||
| 100mg | 926.00 € | ||
| 500mg | 1,846.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
SB 699551 dihydrochloride
CAS:864741-95-7
SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.
Formula:
C34H47Cl2N3O
Purity:
96.53%
Color and Shape:
Solid
Molecular weight:
584.66
Ref: TM-T23325
| 1mg | 51.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 440.00 € | ||
| 100mg | 603.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
F13714 fumarate
CAS:208109-39-1
F13714 fumarate is a 5-HT1A receptor-biased agonist.
Formula:
C25H29ClF2N4O5
Color and Shape:
Liquid
Molecular weight:
538.97
Ref: TM-T37622
| 1mg | 55.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 27 Jan 2025
(±)-AC 7954 hydrochloride
CAS:477313-09-0
(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.
Formula:
C19H21Cl2NO2
Purity:
99.42%
Color and Shape:
White Solid
Molecular weight:
366.28
Ref: TM-T22476
| 1mg | 88.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 671.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,850.00 € | ||
| 1mL*10mM (DMSO) | 201.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Elinogrel
CAS:936500-94-6
Elinogrel (PRT060128) is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 …
Formula:
C20H15ClFN5O5S2
Purity:
97.09%
Color and Shape:
Solid
Molecular weight:
523.95
Ref: TM-T11177
| 1mg | 56.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 388.00 € | ||
| 100mg | 543.00 € | ||
| 200mg | 775.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
2-Arachidonoylglycerol
CAS:53847-30-6
In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand
Formula:
C23H38O4
Purity:
95%
Color and Shape:
Liquid
Molecular weight:
378.55
Ref: TM-T14011
| 1mg (26.4mM*100μL in Acetonitrile) | 113.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
OPC-14523 hydrochloride
CAS:145969-31-9
OPC-14523 hydrochloride, an oral sigma/5-HT1A agonist, shows potent antidepressant activity with strong receptor affinity.
Formula:
C23H29Cl2N3O2
Purity:
99.70%
Color and Shape:
Liquid
Molecular weight:
450.4
Ref: TM-T62711
| 5mg | 889.00 € | ||
| 10mg | 1,181.00 € | ||
| 25mg | 1,483.00 € | ||
| 50mg | 1,814.00 € | ||
| 100mg | 2,290.00 € | ||
| 1mL*10mM (DMSO) | 942.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
GR 46611
CAS:185259-85-2
GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in …
Formula:
C23H27N3O2
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
377.48
Ref: TM-T22808
| 1mg | 52.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 425.00 € | ||
| 100mg | 620.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Litoxetine
CAS:86811-09-8
Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, …
Formula:
C16H19NO
Purity:
99.12%
Color and Shape:
Liquid
Molecular weight:
241.33
Ref: TM-T67956
| 1mg | 95.00 € | ||
| 5mg | 214.00 € | ||
| 10mg | 319.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 782.00 € | ||
| 100mg | 1,077.00 € | ||
| 500mg | 2,168.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
(R)-ZINC-3573
CAS:2089389-15-9
ZINC-3573: Potent, selective MRGPRX2 activator; triggers mast cell degranulation and calcium release.
Formula:
C18H21N5
Purity:
100%
Color and Shape:
Solid
Molecular weight:
307.39
Ref: TM-T29221
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Donitriptan
CAS:170912-52-4
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and …
Formula:
C23H25N5O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
403.48
Ref: TM-T11075
| 1mg | 55.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 627.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Radioprotectin-1
CAS:1622006-09-0
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 …
Formula:
C23H19ClN2O6S
Purity:
98.75% - 99.43%
Color and Shape:
Solid
Molecular weight:
486.92
Ref: TM-T12684
| 1mg | 79.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 253.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 754.00 € | ||
| 1mL*10mM (DMSO) | 182.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
L-745870
CAS:158985-00-3
L-745870 is a selective dopamine D4 antagonist, brain-penetrant, with lesser affinity for D2/D3 receptors (Ki: …
Formula:
C18H19ClN4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
326.82
Ref: TM-T11799L
| 2mg | 41.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
