Alpha blockers

<p>Applications Methyl 1,4-Benzodioxan-2-carboxylate is an intermediate used to prepare 2,3-dihydrobenzo[b|[1,4|dioxin- and indolealkylamine derivatives as potential antidepressants.<br>References Wang, S., et al.: Archiv der Pharmazie (Weinheim, Germany), 347, 32 (2014); Wang, S., et al.: Bioorg. Med. Chem. Lettt., 24, 1766 (2014)<br></p>

<p>Applications 2-Chloro-3-cyanopyridine (cas# 6602-54-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Dehydro Silodosin is an impurity of Silodosin (S465000).<br>References Moriyama., et al.: Eur. J. Pharmacol., 331, 39 (1997), Zhu, J., et al.: Br. J. Pharmacol., 131, 546 (2000),<br></p>

<p>Applications N-Formyl Cardevilol is an impurity of Carvedilol (C184625).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Carvedilol (C184625) derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Tamsulosin Ether is an impurity of is a Tamsulosin(CAS:106133-20-4) a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),<br></p>

<p>Applications A metabolite of the antihypertensive agent, Labetalol (L096500).<br>References Gal, J., et al.: Res. Comm. Chem. Pathol. Pharmacol., 62, 3 (1988),<br></p>

<p>Applications A Labelled metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.<br>References Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 958 (1998).<br></p>

<p>Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>

<p>Applications R-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects.<br>References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)<br></p>

<p>Applications 3,4-Dichloro Trazodone is the dichlorinated analogue and impurity of the antidepressant agent Trazodone (T718500).<br>References Pai, N.R. et al.: J. Chem. Pharmac. Res., 2, 458 (2010); Pai, N. et al.: Int. J. Pharmac. Sci. Rev. Res., 4, 180 (2010);<br></p>

<p>Stability Hygroscopic<br>Applications A possible metabolite of Trazodone-HCl (T718500).<br></p>

<p>Applications (αR)-4-Methoxy-α-methyl-N-[(1R)-1-phenylethyl]benzeneethanamine is used in the symthesis of Formoterol (F693400).<br>References Hett, R., et al.: Tetrahedron Lett., 38, 1125 (1997),<br></p>

<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity. [α]D= -18.7 (c= 0.1 methanol)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>